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Influencing factors of medication discrepancy in patients with coronary heart disease during hospital-family transition period

Medicine (Baltimore). 2025 May 16;104(20):e42473. doi: 10.1097/MD.0000000000042473.

ABSTRACT

Patients with coronary heart disease may have a higher risk of medication discrepancy during hospital-family transition period because of the complexity of their diseases, the diversity of medicines brought out of hospital and the sensitivity of medicine taking time. This study aims to analyze the influencing factors of medication discrepancy in patients with coronary heart disease during hospital-family transition period. Patients admitted to the department of cardiovascular medicine from July 1, 2023 to June 30, 2024 in a hospital in Ningbo City, Zhejiang Province, China. Electronic medical record system and patients themselves before discharge collected the baseline data of patients with coronary heart disease. Within 2 weeks after discharge, the patients were investigated by telephone follow-up with the medication discrepancy tool. Logistic regression was used to determine the influencing factors of patients’ medication discrepancy. The incidence of medication discrepancy in 107 patients within 2 weeks after discharge was 23.4%. The main discrepancy type is “medication omission.” The causes of patient-induced medication discrepancy are relatively high, and the most common reason is “forgetting to take medicine.” Logistic regression analysis showed that aspirin medication history and family APGAR index were the influencing factors of medication discrepancy. The incidence of medication discrepancy in patients with coronary heart disease in hospital-family transition period is high, among which omission is the most common. Aspirin medication history and family function are the key to identify patients’ medication discrepancy. Medical staff should pay attention to the management of medication discrepancy in patients with coronary heart disease.

PMID:40388747 | DOI:10.1097/MD.0000000000042473

By Nevin Manimala

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