Plast Aesthet Nurs (Phila). 2025 Jul-Sep 01;45(3):163-172. doi: 10.1097/PSN.0000000000000609. Epub 2025 Jul 9.
ABSTRACT
This real-world data evaluation assesses the effectiveness of a hyaluronic acid-based product (Profhilo®, IBSA Farmaceutici Italia, Lodi, Italy) for improving neck skin laxity, firmness, tone, and texture in a satisfaction survey involving 26 patients from Malaysia (n = 9), Singapore (n = 9), and Indonesia (n = 8). Each patient received two treatments: the first at baseline, and the second on Day 30. Using the IBSA Neck Skin Laxity Scale (IBSA NSLS), physicians evaluated photographs of the patients’ necks at baseline, Day 30, and Day 90. Before treatment on Day 30 and at the follow-up visit on Day 90, physicians and patients assessed clinical improvement and satisfaction related to skin laxity, firmness, and texture. After each treatment, the patients recorded their pain level using a visual analogue scale. The mean IBSA NSLS grades for all patients significantly decreased from 3.08 at baseline to 2.12 at follow-up (p < .0001). At Day 90, the most frequent response from all participants was that their neck laxity and skin firmness and tone was either improved or much improved and their skin texture was very much improved. Following the injections, the patients reported low to moderate pain levels. In this real-world satisfaction survey involving patients from Malaysia, Singapore, and Indonesia, the physicians concluded that Profhilo® was an effective and well tolerated treatment for improving neck skin laxity, firmness, tone, and texture in patients of varying ages, genders, and baseline skin laxity and wrinkle severity.
PMID:40627798 | DOI:10.1097/PSN.0000000000000609
