Intern Emerg Med. 2025 Aug 6. doi: 10.1007/s11739-025-04072-5. Online ahead of print.
ABSTRACT
In cardiac arrest (CA) patients, arterial blood gas parameters, such as pH values, lactate concentrations, and base deficit (BD), are routinely evaluated in the emergency department (ED). We examined the relationship between BD and successful cardiopulmonary resuscitation (CPR), return of spontaneous circulation (ROSC), neurological surveys, and intensive care unit (ICU) hospitalization length for in-and out-of-hospital CA (IHCA and OHCA, respectively) patients. We included non-traumatic adult CA patients in the present study. Age, gender, arterial blood gas (ABG) test results, CPR duration, ROSC, ICU hospitalization length, 30-day surveys, and neurological surveys were obtained for each patient. We included 448 CA patients. The mean age of the study group was 62.80 ± 17.64 years. The number of OHCA patients was 251 (56%), and IHCA patients consisted of 197 (44%). Mean BD values of the non-surviving OHCA patients was – 16.67 ± 6.72. This corresponding value in survival patients value was – 14.89 ± 6.62, but the difference was not statistically significant (p = 0.420). In the IHCA group, a weak negative correlation between BD levels and CPR duration (p < 0.001, r = – 0.247) was found. A weak positive correlation between BD and ICU hospitalization length (p < 0.001, r = 0.342) was also found. CPR duration correlated weakly and negatively with BD in the OHCA group (p = 0.03, r = – 0.192). In the IHCA group, BD was related to both ROSC (p < 0.001) and 30-day survival (p < 0.001). In the OHCA group, BD was related to ROSC (p = 0.020) and 30-day surveys (p = 0.042). In the IHCA group, a weak negative correlation between BD levels and CPR duration in addition to a weak positive correlation between BD and ICU hospitalization length was found. CPR duration negatively correlated with BD in the OHCA group.
PMID:40768124 | DOI:10.1007/s11739-025-04072-5
