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Spatio-temporal analysis of human visceral leishmaniasis in the Central-West region of Brazil from 2010 to 2019

Trans R Soc Trop Med Hyg. 2025 Sep 16:traf092. doi: 10.1093/trstmh/traf092. Online ahead of print.

ABSTRACT

BACKGROUND: Visceral leishmaniasis (VL) is considered a neglected tropical disease with high lethality. This study aimed to analyze the spatio-temporal dynamics of VL in the Central-West region of Brazil, from 2010 to 2019.

METHODS: Using data obtained from the Sistema de Informação de Agravos de Notificações (SINAN) from Brazil and spatio-temporal analysis tools, an ecological study of VL cases was carried out considering each federated unit in the Central-West region from 2010 to 2019.

RESULTS: It was observed that state of Mato Grosso do Sul had the majority of municipalities with high incidence in all temporal series analyzed. A heterogeneous distribution of VL with spatial clustering in the state of Mato Grosso do Sul was observed. Furthermore, Goiás and Mato Grosso also presented high-risk municipalities, with clusters of higher relative risk (RR) observed from 2013 to 2017 in Goiás and from 2010 to 2013 in Mato Grosso.

CONCLUSIONS: Therefore, it is observed that the states of Goiás, Mato Grosso and Mato Grosso do Sul need greater attention to support the adoption of effective measures to control VL in the Brazilian Central-West region.

PMID:40971974 | DOI:10.1093/trstmh/traf092

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