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Five-Item Modified Frailty Index Score is Associated With Increased Postoperative Complications Following Ankle Fracture ORIF

Foot Ankle Spec. 2025 Nov 1:19386400251383440. doi: 10.1177/19386400251383440. Online ahead of print.

ABSTRACT

BackgroundThis study aims to analyze the effect of preoperative 5-factor modified frailty index (mFI-5) on 30-day complication, readmission, reoperation, and mortality rates following ankle fracture open reduction and internal fixation (ORIF).MethodsThe American College of Surgeons (ACS NSQIP) database was queried to identify 44 838 patients undergoing ankle fracture ORIF. Patients were stratified into groups based on preoperative mFI-5 scores.ResultsThe cohort was predominantly male (59.0%), and the mean age was 49.52 (range = 16-89) years. The mFI-5 score was statistically significantly predictive of any complication (P < .001), serious medical complication (P < .001), surgical site infection (P <.001), readmission (P <.001), reoperation (P <.001), mortality (P <.001), adverse discharge (P <.001), and increased hospital length of stay (LOS) (P <.001).ConclusionOur results indicate that mFI-5 score is a useful predictive measure for postoperative complications, adverse discharge, readmission, reoperation, mortality, and increased LOS in patients undergoing ankle fracture ORIF.Levels of Evidence:Level III, Retrospective cohort study.

PMID:41175018 | DOI:10.1177/19386400251383440

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