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Factors associated with the occurrence of COVID-19 in the pediatric population in hospital settings: a case-control study

Rev Esc Enferm USP. 2025 Nov 17;59:e20250211. doi: 10.1590/1980-220X-REEUSP-2025-0211en. eCollection 2025.

ABSTRACT

OBJECTIVE: To analyze factors associated with the occurrence of COVID-19 in the pediatric population in hospital settings.

METHOD: This was a paired case-control study conducted with medical records of children under 14 years of age. The pediatric population with a positive COVID-19 test was considered a case, and the pediatric population with a negative COVID-19 test was considered a control. For each case, a control was used, totaling 486 medical records. Descriptive analysis, bivariate analysis, and logistic regression were performed.

RESULTS: The variables associated with the occurrence of COVID-19 were brown, black, yellow, and indigenous children, emergency room and Intensive Care Unit admission, use of mask and oxygen catheter, antimicrobials, and corticosteroids. Fever, anorexia, non-eupneic respiratory pattern with saturation between 90% and 95%, cough, runny nose, and comorbidities were associated with the outcome.

CONCLUSION: Advances by providing information on factors associated with COVID-19 in the hospitalized population under 14 years of age, including place of hospitalization, anorexia, runny nose, comorbidity, and corticosteroid use.

PMID:41313640 | DOI:10.1590/1980-220X-REEUSP-2025-0211en

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