Zh Nevrol Psikhiatr Im S S Korsakova. 2025;125(11):111-116. doi: 10.17116/jnevro2025125111111.
ABSTRACT
OBJECTIVE: To study the risk factors for a slowed intra-atrial conduction in patients with schizophrenia.
MATERIAL AND METHODS: One hundred twenty-two electrocardiograms of patients with schizophrenia who took antipsychotics were analyzed. The components of the metabolic syndrome, as well as anthropometric parameters, were identified as potential risk factors.
RESULTS: Slowed intra-atrial conduction (P >0.10 s) was found in 21 (17.2%) patients. Therefore, the patients were divided into two groups depending on the presence or absence of slowed intra-atrial conduction. Male sex (p=0.031), the duration of basic therapy (p<0.001), hypertriglyceridemia (p=0.043), the presence of metabolic syndrome (p=0.015), and hypersthenic body type (p<0.001) were statistically significant risk factors for slowed intra-atrial conduction in patients with schizophrenia.
CONCLUSION: If these risk factors are identified in patients with schizophrenia, continuous monitoring of the electrocardiogram and pharmacological interventions are recommended for the identified indications.
PMID:41362983 | DOI:10.17116/jnevro2025125111111