Yi Chuan. 2026 Feb 20;48(2):158-176. doi: 10.16288/j.yczz.25-214.
ABSTRACT
Codon usage bias (CUB) refers to the non-random usage of synonymous codons during protein translation. It holds significant value for understanding species evolution, environmental adaptation, gene expression regulation, and population genetic diversity. In this review, we summarize the biological significance of codon usage bias, outline commonly used statistical approaches for its analysis, and provide a comprehensive overview of recent advances in codon usage research within the field of entomology. This work aims to offer new perspective and methodologies insights to support further in-depth studies of codon usage patterns in insects.
PMID:41669808 | DOI:10.16288/j.yczz.25-214
