Med Princ Pract. 2021 Jun 23. doi: 10.1159/000517976. Online ahead of print.
ABSTRACT
OBJECTIVE: The aim of the study was to ascertain the effect of nasal polyposis on cardiac functions.
MATERIAL AND METHODS: A prospective randomized interventional open-label endpoint-controlled study was conducted in an academic tertiary care hospital. Thirty-one patients with chronic rhinosinusitis with nasal polyposis were enrolled and administered fluticasone furoate nasal spray for 3 weeks before randomly segregation into surgical or medical group. The treatment continued for 3 months in both groups. The SNOT-22 (Sino-Nasal Outcome Test-22) score, polyp grade, and right ventricular and pulmonary arterial functions were recorded in both groups before and after 3 months of the intervention.
RESULTS: Both groups had significant improvement in SNOT-22 scores after 3 months of intervention. Both groups showed improvement in cardiac functions, but statistical significance was found only in subjects who underwent surgery.
CONCLUSION: Nasal polyp affects cardiac functions, and this needs further evaluation and research through studies on large samples.
PMID:34348323 | DOI:10.1159/000517976
