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Nevin Manimala Statistics

Suitability of determining percentage hearing loss for monitoring cochlear implant rehabilitation

HNO. 2023 Jan 2. doi: 10.1007/s00106-022-01257-8. Online ahead of print.

ABSTRACT

BACKGROUND: Calculation of percentage hearing loss (pHV) from the pure-tune audiogram according to Röser in 1973 or from the speech audiogram according to Boenninghaus and Röser in 1973 is a method still applied for quantitative assessment of hearing. However, this is not common for the evaluation of postoperative results of implantable hearing systems. During the regular work-up after cochlear implantation (CI) in Germany, all necessary parameters are available for calculation of pHV either from categorical loudness scaling (pHVKLS) or speech-recognition threshold (pHVFB).

OBJECTIVE: The parameters pHVKLS and pHVFB are introduced and calculated from data available from clinical routine. Their potential applicability for assessment of the result of CI is evaluated.

MATERIALS AND METHODS: This study comprises retrospective chart review of audiological parameters from 66 CI procedures in one tertiary referral center. pHVKLS was calculated from the equal loudness curve 5 CU, pHVFB from the Freiburg speech test in free field.

RESULTS: While pHVKLS shows small variation, the variation in pHVFB is initially larger but decreases over time. Furthermore, starting from initial fitting, the mean pHV shows convergence over time. The difference between pHVFB and pHVKLS is positive and statistically significant.

CONCLUSION: It is possible to calculate pHVKLS and pHVFB from routine data. A correlation of the difference between pHVFB and pHVKLS with successful CI performance seems plausible.

PMID:36592183 | DOI:10.1007/s00106-022-01257-8

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The association between cold exposure and musculoskeletal disorders: a prospective population-based study

Int Arch Occup Environ Health. 2023 Jan 2. doi: 10.1007/s00420-022-01949-2. Online ahead of print.

ABSTRACT

OBJECTIVES: The aim of the study was to determine the association between occupational ambient cold exposure and neck-shoulder pain (NSP), low back pain (LBP), and radiating LBP.

METHODS: The study cohort comprised of 3,843 working subjects in northern Sweden who answered a baseline (spring 2015) and a follow-up questionnaire (spring 2021). NSP, LBP, and radiating LBP were assessed in both surveys. Occupational cold exposure was assessed at baseline, on a whole number numerical rating scale (NRS) and categorized in quartiles. Binary logistic regression determined the association between cold exposure at baseline and incident NSP, LBP, and radiating LBP, adjusted for age, gender, body mass index, smoking, mental stress, and physical workload.

RESULTS: There were statistically significant associations between high occupational ambient cold exposure (NRS 5-7 and NRS 8-10) and NSP (1.59; 95% CI 1.08-2.33 and OR 1.50; 95% CI 1.03-2.19); NRS 8-10 and LBP (OR 1.61; 95% CI 1.13-2.29); and NRS 5-7 and radiating LBP (OR 1.87; 95% CI 1.12-3.16). Gender-stratified analyses showed statistically significant associations between high occupational ambient cold exposure (NRS 5-7 and NRS 8-10) and NSP (OR 1.97; 95% CI 1.07-3.61 and OR 1.97; 95% CI 1.06-3.67) for men and between NRS 8-10 and LBP (OR 1.82; 95% CI 1.14-2.91) and NRS 5-7 and radiating LBP (OR 2.20; 95% CI 1.15-4.24) for women.

CONCLUSIONS: Occupational ambient cold exposure was associated with NSP, LBP, and radiating LBP, and should be recognised as a possible occupational risk factor.

PMID:36592178 | DOI:10.1007/s00420-022-01949-2

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Nevin Manimala Statistics

The effect of M technique massage on behavioral state and weight gain in preterm neonates: A randomized controlled trial

J Child Health Care. 2023 Jan 2:13674935221147714. doi: 10.1177/13674935221147714. Online ahead of print.

ABSTRACT

This study aimed to investigate the effect of M technique massage on behavioral state and weight gain in preterm neonates admitted to neonatal intensive care unit (NICU). This was a randomized controlled trial study in which a total of 64 preterm neonates were randomly allocated to intervention and control group. Intervention group received M technique massage and control group received routine care. Neonatal weight and behavioral state were measured for two weeks. After intervention, no statistically significant difference was found between groups in terms of neonatal weight (mean difference: 44.03, 95% CI [-180.66, 268.74]). At baseline, the mean score for behavioral state response was 5.84 ± 2.20 (mean ± SD) in control group and 5.68 ± 2.15 (mean ± SD) in intervention group and the difference was not significant (mean difference: 0.16, 95% CI [-1.21, 1.52]), but 2 weeks later, and also, after intervention, a statistically significant difference was found between groups (mean difference: 2.16, 95% CI [1.19, 3.17]) and (mean difference: 3.03, 95% CI [2.15, 3.91]), respectively, meaning that it was significantly lower in intervention group compared with control group. According to the findings, massage with M technique in premature neonates can have a positive effect on behavioral state, but no effect on their weight gain.

PMID:36592155 | DOI:10.1177/13674935221147714

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Nevin Manimala Statistics

Validity and Reliability of the Turkish Version of the Munich Chronotype Questionnaire

Turk Psikiyatri Derg. 2022 Winter;33(4):274-279. doi: 10.5080/u26079.

ABSTRACT

OBJECTIVE: The Morningness-Eveningness Questionnaire (MEQ) has been widely used to determine chronotype. The Munich Chronotype Questionnaire (MCTQ) was developed as an alternative measurement tool to the MEQ, focusing on different sleep behaviors on work and free days. The aim of this study was to adapt the MCTQ to the Turkish language and to validate the questionnaire on young and healthy adult members of the Turkish population.

METHOD: This study was conducted with total of 214 (161 Female, 53 Male) healthy young adult volunteers between the ages of 18-30 (M=20.72, SD=2.33) from Hacettepe University. After adaptation to the Turkish language to form the MCTQ-TR, the psychometric properties were compared with the MEQ-TR. The test retest reliability of the MCTQ-TR was investigated on 25 participants (19 Female, 6 Male), 4 months after the first application.

RESULTS: The test-retest reliability coefficient of the MCTQ-TR was calculated as r=0.643 (p<0.05). The validity and reliability results indicated a negative and statistically significant correlation between the MEQ-TR and MCTQ-TR scores (r=-0.627; p<0.001).

CONCLUSION: The MCTQ-TR is a valid and reliable measurement tool that can be used to determine chronotype in healthy Turkish young adult population.

PMID:36592106 | DOI:10.5080/u26079

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Comparison of Formal Thought Disorder in the Acute Episode of Schizophrenia and Manic Episode of Bipolar Affective Disorder

Turk Psikiyatri Derg. 2022 Winter;33(4):223-232. doi: 10.5080/u25886.

ABSTRACT

OBJECTIVE: The aim of this study was to compare the formal thought disorder (FTD) in the acute episode of schizophrenia (SCHZ) and bipolar affective disorder (BPAD), and to determine the FTD dimensions associated with BPAD.

METHOD: The study included a total of 34 SCHZ patients not meeting the standardized remission criteria and 20 patients in BPAD manic episode. The patients completed the Positive and Negative Syndrome Scale (PANSS), the Clinical Global Impression Scale (CGI), the Young Mania Rating Scale (YMRS), the Hamilton Depression Rating Scale (HAM-D) and the Thought and Language Disorder Scale (TALD) in order to assess FTD. The association of FTD with the diagnoses was analyzed by a logistic regression model including the TALD factors and the SCHZ and BPAD groups.

RESULTS: Statistically significant differences were not determined between the demographic features, the CGI scores and the TALD objective positive factor scores of the SCHZ and BPAD groups. The objective negative and subjective negative factors (p<0.001 for all) were higher in SCHZ group and the subjective positive factor were significantly higher in BPAD group (p=0.028). In the logistic regression model, the TALD subjective positive factor was associated with BPAD diagnosis, and the objective negative factor was associated with SCHZ diagnosis. In the BPAD group, the TALD total score correlated positively with the manic episode severity, and the scores on the subjective negative and subjective positive factors correlated negatively with disease duration.

CONCLUSION: The study results show that FTD is common to the acute episodes of both SCHZ and BPAD and that assessment of the subjective positive FTD symptoms and objective negative FTD symptoms may be useful to differentiate the acute episode of SCHZ from the BPAD manic episode.

PMID:36592101 | DOI:10.5080/u25886

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Nevin Manimala Statistics

What are the benefits of using self-management plans for COPD patients in the community: a critical review of the literature

Br J Community Nurs. 2023 Jan 2;28(1):22-32. doi: 10.12968/bjcn.2023.28.1.22.

ABSTRACT

AIM: To critically appraise the literature to assess the benefits of self-management plans in COPD patients in the community setting.

DISCUSSION: A total of eight papers were included in this review: three qualitative and five randomised control trials (RCT), with one being a pilot study. The statistical significance of using COPD self-management plans was minimal. However, when exploring subsections of some of the trials, there was some data suggesting there was some health-related quality of life improvement.

CONCLUSION: Further research is required to gain a valuable perspective from individual patients in regards to what they want to be included in a management plan and how this can be implemented into practice.

PMID:36592089 | DOI:10.12968/bjcn.2023.28.1.22

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Nevin Manimala Statistics

Vitamin C Status of US Adults Assessed as Part of the National Health and Nutrition Examination Survey Remained Unchanged between 2003-2006 and 2017-2018

J Appl Lab Med. 2023 Jan 2:jfac093. doi: 10.1093/jalm/jfac093. Online ahead of print.

ABSTRACT

BACKGROUND: We compared serum vitamin C (VIC) status of the adult (≥20 y) US population in the National Health and Nutrition Examination Survey (NHANES) 2017-2018 with combined data from 2003-2004 and 2005-2006.

METHODS: VIC was measured using HPLC with electrochemical detection. Mean data were stratified by age, sex, race/Hispanic origin, income, body mass index, dietary intake, supplement use, and smoking status. Prevalence of VIC deficiency (<11.4 μmol/L) was calculated.

RESULTS: In NHANES 2017-2018, the mean VIC was 8 μmol/L higher in people ≥60 y compared with those 20-59 y of age, 10 μmol/L lower in men vs women, 8 μmol/L lower in low vs high income, 11 μmol/L lower in obese vs healthy weight, and 15 μmol/L lower in smokers vs nonsmokers. Differences in mean VIC across race/Hispanic origin groups ranged from 2 to 7 μmol/L. Mean VIC was 27 μmol/L higher with vitamin C-containing supplement use and positively associated (Spearman ρ = 0.33; P < 0.0001) with increasing dietary intake. The associations between mean VIC and the investigated covariates were generally consistent and the prevalence of deficiency was not significantly different between survey periods (6.8% vs 7.0%; P = 0.83). However, a few subgroups had double the risk. We found no significant survey differences in mean VIC (51.2 vs 54.0 μmol/L; P = 0.09).

CONCLUSIONS: Overall VIC status of the US adult population has remained stable since last assessed in the NHANES 2005-2006 survey. Vitamin C deficiency remained high for those with low dietary intake and who smoke.

PMID:36592081 | DOI:10.1093/jalm/jfac093

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Nevin Manimala Statistics

Severe and Moderate Primary Graft Dysfunction in Adult Heart Recipients

Braz J Cardiovasc Surg. 2022 Dec 19. doi: 10.21470/1678-9741-2022-0107. Online ahead of print.

ABSTRACT

INTRODUCTION: The aims of this study were to determine the incidence of severe and moderate primary graft dysfunction (PGD) in our center, to identify, retrospectively, donors’ and recipients’ risk factors for PGD development, and to evaluate the impact of PGD within 30 days after heart transplantation.

METHODS: Donors’ and recipients’ medical records of 64 consecutive adult cardiac transplantations performed between January 2016 and June 2017 were reviewed. The International Society for Heart and Lung Transplantation (ISHLT) criteria were used to diagnose moderate and severe PGD. Associations of risk factors for combined moderate/severe PGD were assessed with appropriate statistical analyses.

RESULTS: Sixty-four patients underwent heart transplantation in this period. Twelve recipients (18.7%) developed severe or moderate PGD. Development of PGD was associated with previous donor cardiopulmonary resuscitation and a history of prior heart surgery in the recipient (P=0.01 and P=0.02, respectively). The 30-day in hospital mortality was similar in both PGD and non-PGD patients.

CONCLUSION: The use of the ISHLT criteria for PGD is important to identify potential risk factor. The development of PGD did not affect short-term survival in our study. More studies should be done to better understand the pathophysiology of PGD.

PMID:36592073 | DOI:10.21470/1678-9741-2022-0107

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Proposed Risk Score in Patients with Aortic Stenosis Submitted to Valve Replacement Surgery

Braz J Cardiovasc Surg. 2022 Dec 19. doi: 10.21470/1678-9741-2022-0254. Online ahead of print.

ABSTRACT

INTRODUCTION: Due to Brazilian population aging, prevalence of aortic stenosis, and limited number of scores in literature, it is essential to develop risk scores adapted to our reality and created in the specific context of this disease.

METHODS: This is an observational historical cohort study with analysis of 802 aortic stenosis patients who underwent valve replacement at Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul, from 1996 to 2018. With the aid of logistic regression, a weighted risk score was constructed based on the magnitude of the coeficients β of the logistic equation. Two performance statistics were obtained: area under the receiver operating characteristic curve and the chi-square (χ2) of Hosmer-Lemeshow goodness-of-fit with Pearson’s correlation coeficient between the observed events and predicted as a model calibration estimate.

RESULTS: The risk predictors that composed the score were valve replacement surgery combined with coronary artery bypass grafting, prior renal failure, New York Heart Association class III/IV heart failure, age > 70 years, and ejection fraction < 50%. The receiver operating characteristic curve area was 0.77 (95% confidence interval: 0.72-0.82); regarding the model calibration estimated between observed/predicted mortality, Hosmer-Lemeshow test χ2 = 3,70 (P=0.594) and Pearson’s coeficient r = 0.98 (P<0.001).

CONCLUSION: We propose the creation of a simple score, adapted to the Brazilian reality, with good performance and which can be validated in other institutions.

PMID:36592072 | DOI:10.21470/1678-9741-2022-0254

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Comparison of Surgical Techniques Used in Ventricular Septal Defect Closure

Braz J Cardiovasc Surg. 2022 Dec 19. doi: 10.21470/1678-9741-2022-0059. Online ahead of print.

ABSTRACT

INTRODUCTION: We compared transatrial closure, tricuspid valve septal detachment, and tricuspid valve chordal detachment techniques for ventricular septal defect (VSD) closure.

METHODS: Patients who had VSD closure with three different techniques in our clinic between September 2016 and December 2020 were retrospectively reviewed. A total of 117 patients were included in the study. The patients were divided into three groups: group 1, classical transatrial closure; group 2, closure with tricuspid valve septal detachment; and group 3, closure with tricuspid valve chordal detachment. The groups were evaluated by serial transthoracic echocardiography (preoperative, postoperative 1st day, postoperative 1st month). Cardiac rhythm checks and recordings were performed.

RESULTS: No residual VSD was observed in early or late periods in any of the groups whose VSD closure was performed with the three different techniques. No severe tricuspid regurgitation (TR) was detected during the early and late postoperative periods of all operating procedures. When the groups were compared in terms of early/late TR after the operation (without TR+trace amount of TR and mild TR+moderate TR were compared), no statistically significant difference was found (P>0,05; P=0,969 and P>0,05; P=0,502).

CONCLUSION: In this study, we found no statistically significant difference between three VSD closure techniques in terms of early TR, late TR, residual VSD, and permanent atrioventricular complete block during postoperative period. We hope that our results will be supported by the results of researches that are being made about this subject in large series.

PMID:36592069 | DOI:10.21470/1678-9741-2022-0059