Category: Nevin Manimala

Int J Oral Maxillofac Implants. 2022 Jan-Feb;37(1):114-119. doi: 10.11607/jomi.9116.

ABSTRACT

PURPOSE: The stability and density of the grafted bone in the maxillary sinus are essential for dental implant survival. This study aimed to compare bone density following mineralized allogeneic bone and deproteinized bovine bone and evaluate the volumetric changes as the secondary outcome.

MATERIALS AND METHODS: In this prospective cohort study, subjects were randomly allocated into two groups of mineralized bone and deproteinized bone to augment the maxillary sinus. Subjects underwent CBCT immediately after augmentation and 9 months later. The relative bone density was the primary outcome, and the volumetric change after 9 months was the secondary outcome of the study. The authors used an independent t test for assessing the bone density and volumetric change between the two groups.

RESULTS: Fifty patients were studied (n = 25 in each group). At 9 months after sinus elevation, the mean bone density was 237.20 ± 55.72 Hounsfield units (HU) in group 1 (mineralized bone) and 634.8 ± 166.11 HU in group 2 (deproteinized bone). There was a substantial difference statistically for the mean of HU between groups 1 and 2 (P < .001). The mean volume change was 0.25 ± 0.13 cm³ in group 1 (mineralized bone) and 0.06 ± 0.05 cm³ in group 2 (deproteinized bone). Assessment of the data showed a substantial difference in the mean volume change at 9 months after sinus elevation between groups 1 and 2 (P < .001).

CONCLUSION: Considering the results of this study, the deproteinized bone was associated with higher relative bone density than the mineralized bone 9 months after sinus elevation. The volume change of the deproteinized bone was less than the mineralized bone in the study time.

PMID:35235629 | DOI:10.11607/jomi.9116

Int J Oral Maxillofac Implants. 2022 Jan-Feb;37(1):135-142. doi: 10.11607/jomi.9064.

ABSTRACT

PURPOSE: Primary stability is the most important prognostic index for predicting osseointegration. It is generally thought that to achieve high primary stability, it is necessary to insert an implant with a high insertion torque (IT). To date, it has not yet been determined whether IT and implant stability quotient (ISQ) values are correlated. The primary aim of the study was to determine the correlation between IT and ISQ values at the time of implant insertion (T0); at 2 months, the time of healing (T1); and at 6 (T2) and 12 months (T3) after loading. The secondary aims were to determine the influence of different macroscopic implant designs and of a different insertion arch on this correlation; and to assess whether implants inserted with a high IT, that is, > 50 Ncm, had higher levels of implant stability at 2-, 6-, and 12-month follow-ups.

MATERIALS AND METHODS: STROBE guidelines were followed. Partially or monoedentulous patients were randomly assigned to receive taper thread on straight-body implants with microthreads (group A) or without microthreads (group B). At implant insertion, IT and ISQ values were recorded. At 2-, 6-, and 12-month follow-ups, the ISQ values were recorded. A spring-style torque wrench was used to assess the IT. The Osstell device was used to determine the ISQ values. Descriptive statistics, Pearson correlation, and t test were used. P was set at ≤ .005.

RESULTS: Two hundred fifty subjects were assessed; 142 were included. Two hundred sixty-eight implants were inserted (group A, 137 implants; group B, 131 implants). No subject dropped out, and no implant failed. A statistically significant correlation between ISQ and IT was determined at the time of implant insertion (T0; P = .000). The implant morphology and arch did not influence the correlation. An IT > 50 did not determine a higher secondary stability.

CONCLUSION: There is a strong correlation between IT and primary stability, but IT is not correlated with the secondary stability. A different implant macroscopic design and a different arch of insertion did not influence this correlation. Moreover, implants inserted with IT > 50 Ncm do not result in greater secondary stability.

PMID:35235632 | DOI:10.11607/jomi.9064

Int J Oral Maxillofac Implants. 2022 Jan-Feb;37(1):e29-e40. doi: 10.11607/jomi.9098.

ABSTRACT

PURPOSE: To investigate whether titanium mesh exposure is influenced by the type of titanium mesh, the type of bone graft material, or the associated employment of absorbable membranes.

MATERIALS AND METHODS: Electronic literature searches were conducted using four databases: PubMed, EMBASE, Web of Science, and Cochrane. Articles reporting titanium mesh exposure rates were included, and exposure rates in different subgroups were compared to determine whether a factor significantly influenced titanium mesh exposure. The review protocol was registered in the PROSPERO registry (CRD42020210187).

RESULTS: Twenty and 12 articles were included in the qualitative and quantitative synthesis, respectively. The weighted exposure rates of employing conventional titanium mesh or 3D-customized titanium mesh were 19.9% and 15.2% (P = .34). When employing autogenous bone combined with anorganic bovine bone material as bone graft material, the weighted exposure rate was 21.7%, whereas when using other bone graft material, the exposure rate was 23.5% (P = .74). The weighted exposure rate of using titanium mesh associated with absorbable membranes is 23.9%, while the weighted exposure rate of using titanium mesh without absorbable membranes is 20.2% (P = .36). Meta-regression showed that when analyzing one factor, the other two confounding factors did not influence the result (P = .28).

CONCLUSION: It seemed that the type of titanium mesh, the type of bone graft material, or the combined employment of absorbable membranes did not statistically significantly influence the titanium mesh exposure rate in guided bone regeneration.

PMID:35235627 | DOI:10.11607/jomi.9098

Int J Oral Maxillofac Implants. 2022 Jan-Feb;37(1):67-75. doi: 10.11607/jomi.9209.

ABSTRACT

PURPOSE: Investigate the effects of three different complete-arch digital implant scanning techniques used with a combined healing abutment-scan body (CHA-SB) system on the accuracy (trueness and precision) and scan time.

MATERIALS AND METHODS: A poly(methyl methacrylate) master model simulating an edentulous maxilla was fabricated with four parallelly inserted dental implants. A CHA-SB system was attached to each implant. The model surface was scanned using a structured blue light industrial extraoral scanner to achieve a reference model standard tessellation language file (MRM-STL). Three different scanning techniques-(1) conventional technique with unmodified master model, (2) scan body splinting technique using orthodontic elastic ligatures and plastic splint materials, and (3) land-marking technique using pyramid-shaped glass-ceramic markers-were performed. Fourteen consecutive digital scans were made by using an intraoral scanner (IOS) for each technique, converted to an STL file, and superimposed on the MRM-STL. Trueness and precision were calculated for each technique. The scan time was also recorded. The data were analyzed with one-way analysis of variance (ANOVA) and Tukey honest significant difference (HSD) tests (α = .05).

RESULTS: Effects of different scanning techniques on the trueness (distance and angular deviations; P < .001) and scan time (P = .002) were statistically significant. For precision, different scanning techniques had only a significant effect on the distance deviation (P < .001).

CONCLUSION: Regarding trueness and precision, none of the scanning techniques was superior to others. The scan body splinting technique led to significantly less scan time.

PMID:35235622 | DOI:10.11607/jomi.9209

Int J Oral Maxillofac Implants. 2022 Jan-Feb;37(1):e13-e27. doi: 10.11607/jomi.9088.

ABSTRACT

PURPOSE: To summarize the methodologic quality and outcome measures from systematic reviews and meta-analyses evaluating the efficacy of different nonsurgical therapies for the treatment of peri-implant diseases.

MATERIALS AND METHODS: Two review authors independently searched for systematic reviews and meta-analyses evaluating the efficacy of different nonsurgical therapies for treatment of peri-implant diseases in three different databases: MEDLINE, Embase, and the Cochrane Library. In addition, journals with a high impact factor in the fields of periodontics, prosthodontics, oral maxillofacial surgery, and implant dentistry were analyzed for potential reviews. The search was implemented from January 2010 through August 2020. Eligible reviews were screened and assessed to determine the characteristics and outcome measures. Furthermore, two review authors independently evaluated the methodologic quality by using the AMSTAR tool and the checklist proposed by Glenny et al. The interrater agreement was assessed by using the Cohen kappa coefficient. The assessment of correlation between the findings of the AMSTAR tool and Glenny et al checklist was performed by using the Spearman correlation.

RESULTS: Fifteen systematic reviews and 12 meta-analyses were evaluated based on the inclusion criteria. One review investigated the efficacy of growth factors and another investigated glycine powder air polishing, 5 evaluated the role of antimicrobial photodynamic therapy, 8 assessed the effect of laser therapy, and 13 compared the different nonsurgical therapies with the surgical therapies for the treatment of peri-implant diseases. The quality assessment score evaluated by the AMSTAR checklist ranged from 5 to 11 with a mean of 7.5 ± 1.8, whereas the score evaluated by the Glenny et al checklist ranged from 3 to 14 with a mean of 9.7 ± 2.8. Spearman correlation analysis between these two tools reported a high correlation (r = 0.91) that was statistically significant (P < .001).

CONCLUSION: The summarized evidence of this overview shows that the different nonsurgical therapies are effective for the treatment of peri-implant mucositis. The lack of sufficient long-term data involving large datasets results in their inconclusive efficacy in the treatment of peri-implantitis. However, the summary is determined from the moderate quality of evidence. Hence, future well-designed high-quality trials are encouraged to reassess the findings.

PMID:35235624 | DOI:10.11607/jomi.9088

PLoS One. 2022 Mar 2;17(3):e0264650. doi: 10.1371/journal.pone.0264650. eCollection 2022.

ABSTRACT

BACKGROUND: Salt impairs endothelial function and increases arterial stiffness independent of blood pressure. The mechanisms are unknown. Recent evidence suggests that there is a possible link between salt consumption and sodium buffering capacity and cardiovascular disease but there is limited evidence in the populations living in Sub-Saharan Africa. The aim of our study was to explore the relationship between erythrocyte sodium buffering capacity and sociodemographic, clinical factors, and self-reported salt consumption at Livingstone Central Hospital.

METHODS: We conducted a cross sectional study at Livingstone Central hospital among 242 volunteers accessing routine medical checkups. Sociodemographic and dietary characteristics were obtained along with clinical measurements to evaluate their health status. Sodium buffering capacity was estimated by erythrocyte sodium sensitivity (ESS) test. We used descriptive and inferential statistics to describe and examine associations between erythrocyte sodium sensitivity and independent variables.

RESULTS: The median age (interquartile range) of the study sample was 27 (22, 42) years. 54% (n = 202) and 46% (n = 169) were males and females, respectively. The majority (n = 150, 62%) had an ESS of >120%. High salt intake correlated positively with ESS or negatively with vascular sodium buffering capacity.

CONCLUSIONS: Self-reported high salt intake was associated with poor vascular sodium buffering capacity or high ESS in the majority of middle-aged Zambians living in Livingstone. The poor vascular sodium buffering capacity implies a damaged vascular glycocalyx which may potentially lead to a leakage of sodium into the interstitium. This alone is a risk factor for the future development of hypertension and cardiovascular disease. However, future studies need to validate vascular function status when using ESS testing by including established vascular function assessments to determine its pathophysiological and clinical implications.

PMID:35235593 | DOI:10.1371/journal.pone.0264650

Int J Oral Maxillofac Implants. 2022 Jan-Feb;37(1):39-48. doi: 10.11607/jomi.9172.

ABSTRACT

PURPOSE: The aim of this study was to compare the trueness and precision of four intraoral scanners (IOSs) and splinted open-tray conventional implant impression (SOCI) in partial and total edentulism.

MATERIALS AND METHODS: Four gypsum models (Model A-implants at mandibular right second molar, right second premolar, and right canine; Model B- implants at mandibular right canine, left central incisor, and left canine; Model C-implants at mandibular right second molar, right second premolar, right canine, left central incisor, and left canine; and Model D-implants at mandibular right second molar, right second premolar, right canine, left central incisor, left canine, left second premolar, and left second molar) were prepared, and four different IOSs (Aadva IOS, CS 3600, Trios 3, and Emerald) and one polyvinyl siloxane (PVS) were used. Reference models were digitized with a high-resolution industrial scanner, and data were superimposed. Root mean square (RMS) values were calculated by software and defined as deviation values after superimposition. The oneway analysis of variance (ANOVA) test and Tukey honest significant difference (HSD) test were performed to analyze the data (P < .05).

RESULTS: For Models A and B, the truest impressions were made with Aadva, followed by CS 3600, PVS, Trios 3, and Emerald, respectively, while for Model C, the truest impressions were made with CS 3600, followed by Aadva, PVS, Trios 3, and Emerald, and for Model D, the truest impressions were made with Aadva, followed by CS 3600, PVS, Emerald, and Trios 3 (P < .05). There was no statistical difference between groups for precision in Models A, B, and C (P > .05); however, PVS showed lower precision values than other groups in Model D (P < .05).

CONCLUSION: In partial edentulism, IOSs are true and precise as SOCI except Emerald. However, the trueness of IOSs is not favorable in total edentulism cases. SOCI with PVS in total edentulism treated with implants is less precise than IOSs.

PMID:35235619 | DOI:10.11607/jomi.9172

PLoS One. 2022 Mar 2;17(3):e0264163. doi: 10.1371/journal.pone.0264163. eCollection 2022.

ABSTRACT

BACKGROUND: Food service in hospital is one of the essential parts of the treatment process that determines recovery length and a hospital stay of patients. Even though many researches have been conducted on patients’ satisfaction with healthcare services, there is a lack of studies that specifically address the satisfaction with food service at healthcare facilities in Ethiopia. This study aimed to assess patient satisfaction with regular hospital food service and associated factors among adults admitted to in-patient departments of hospitals.

METHODS: A hospital-based cross-sectional study design was conducted to interview 423 patients admitted to three randomly selected hospitals namely Wolaita Sodo University Referral and Teaching Hospital, Dubo St. Catholic Hospital and Sodo Christian Hospital. Participants were recruited based on probability proportional to the number of clients in each hospital. After data entry using EpiInfo v7.2.2.6, the data were exported to SPSS v23 software for further analysis. Bivariate and multivariate logistic regressions were undertaken to see the association between variables. Statistically significant variables were declared using an adjusted odds ratio with a 95% confidence interval.

RESULT: Among the total participants 33.6% (95%CI: [29.1, 38.3]) of patients were satisfied with regular hospital food services. Multivariate analysis revealed that residence (AOR = 2.16; 95%CI: [1.28, 3.63]), monthly income (AOR = 5.64; 95%CI: [2.30, 8.28]), flavour of meal, (AOR = 2.63; 95%CI: [1.34, 5.56]), and provision of easily chewable food (AOR = 7.50; 95%CI: [2.00, 12.82]) were influencing factors for satisfaction on hospital foodservices.

CONCLUSION: This research ascertained a low patient satisfaction with regular hospital meal service. The identified factors need to be addressed giving attention for each foodservice dimension to scale up the patient satisfaction with hospital food services.

PMID:35235592 | DOI:10.1371/journal.pone.0264163

PLoS One. 2022 Mar 2;17(3):e0264461. doi: 10.1371/journal.pone.0264461. eCollection 2022.

ABSTRACT

BACKGROUND: Globally, the burden of overweight and obesity is a major cardiovascular disease risk factor and is even higher among patients with psychiatric disorders compared to the general population. This is mainly due to the deleterious lifestyles characterized by physical inactivity, excessive substance use, and unhealthy diets common among patients with psychiatric disorders, as well as the negative metabolic effects of psychotropic medications. Despite these conditions being a high burden among patients with psychiatric illness, little attention is given to them during routine reviews in psychiatric clinics in most African nations, including Ethiopia. Therefore, this study aimed to estimate and compare the prevalence of and associated risk factors for overweight and obesity among patients with psychiatric illnesses.

METHODS: A comparative cross-sectional study was conducted between severely ill psychiatric patients and non-psychiatric patients in Dire Dawa, Eastern Ethiopia. The study included 192 study participants (96 psychiatric patients and 96 non-psychiatric controls). Weight and height were measured for 192 study participants. Baseline demographic and clinical characteristics of psychiatric and non-psychiatric patients were described. The data were cleaned and analyzed using the Statistical Package for Social Sciences, Version 21. The intergroup comparisons were performed using an independent sample t-test and Chi-square tests. Logistic regression analysis was used to identify the association between overweight/obesity and the associated variables.

RESULTS: The magnitude of overweight/obesity was significantly higher in the severely ill psychiatric groups (43.8%) than in the non-exposed controls (20.80%). The prevalence of overweight/obesity was highest in major depressive disorders (40%), followed by schizophrenia (32%), and bipolar disorder (28%).

CONCLUSIONS: There was a high prevalence of obesity/overweight among psychiatric patients. Educational status, unemployment, and late stages of the disease were significant predictors of overweight/ obesity. Clinicians should be aware of the health consequences of overweight/obesity, and considering screening strategies as a part of routine psychiatric care is strongly recommended.

PMID:35235579 | DOI:10.1371/journal.pone.0264461

PLoS One. 2022 Mar 2;17(3):e0264076. doi: 10.1371/journal.pone.0264076. eCollection 2022.

ABSTRACT

INTRODUCTION: Urologic malignancies are the major causes of morbidity and mortality in men over 40 years old, accounting for more than 20% of all malignant tumors. Several meta-analyses are shown that statin exposure can reduce the morbidity and mortality of various urologic cancers. The adjuvant roles of statin in tumor prevention and anti-tumor activity are now being gradually recognized and have gained attention. Nevertheless, to date, multiple clinical studies and meta-analyses found inconsistent results of their anti-cancer effects. This study aims to evaluate the credibility of the published systematic reviews and meta-analyses that assessed the effects of statin exposure for the incidence and mortality of urologic cancers through an umbrella review.

METHODS AND ANALYSIS: The guidance of overviews of systematic reviews reported in the Cochrane Handbook for Systematic Reviews of interventions will be followed while performing and reporting this umbrella review. This project was registered in PROSPERO with the registration number of CRD42020208854. PubMed, Embase and Cochrane Library will be searched for systematic reviews to identify and appraise systematic reviews or meta-analyses of interventional and observational studies examining statin use and the risks of urologic cancer incidence and mortality without language restriction. The search will be carried out on 10 February 2022. Systematic reviews based on qualitative, quantitative or mixed-methods studies will be involved and critically evaluated by two authors using the Assessment of Multiple Systematic Reviews 2 (AMSTAR2, an updated version of AMSTAR) tool. We will determine the level of evidence using the GRADE (Grading of Recommendations, Assessment, Development, and Evaluations) tool. The summary effect estimates will be calculated using random-effects models. Between- study heterogeneity will be assessed using the I2 statistic. Furthermore, we will also assess the evidence of excess significance bias and evidence of small study effects.

ETHICS AND DISSEMINATION: Ethics approval is not required as we will search and gather data based on the published systematic reviews and meta-analyses. We plan to publish the results of this umbrella review in a peer-reviewed journal and will be presented at a urological disease conference. All the relevant additional data will also be uploaded to the online open access databases.

PROSPERO REGISTRATION NUMBER: CRD42020208854.

PMID:35235590 | DOI:10.1371/journal.pone.0264076