Category: Nevin Manimala

Int J Prosthodont. 2021 Mar 3. doi: 10.11607/ijp.6983. Online ahead of print.

ABSTRACT

PURPOSE: To investigate the effect of monolithic zirconia-based occlusal surfaces on signs and symptoms of temporomandibular disorders (TMD) after short-term clinical service.

MATERIALS AND METHODS: Patients were supplied with multi-unit fixed dental prostheses (FDP) featuring monolithic zirconia-based occlusal surfaces. Prior to prosthetic treatment and 1 year after insertion anamnestic facial pain, pain with palpation of muscles/joints and joint sounds were examined.

RESULTS: Of the 50 patients, 43 were re-examined after 1 year. Perceived facial pain was not present, pain with palpation occurred in 2 patients, and TMJ sounds decreased; differences were not statistically significant (P ≥ .058).

CONCLUSION: Single tooth-supported multiunit FDPs featuring monolithic zirconia-based occlusal surfaces did not affect TMD-associated signs and symptoms.

PMID:33662060 | DOI:10.11607/ijp.6983

Int J Prosthodont. 2021 Mar 3. doi: 10.11607/ijp.6345. Online ahead of print.

ABSTRACT

PURPOSE: To measure the retrieval force required to remove 1.5-mm-thick CAD/CAM zirconia copings cemented on zirconia (Zr) and titanium (Ti) stock implant abutments after a single application of erbium-doped yttrium scandium gallium garnet (Er:YSGG) laser.

MATERIALS AND METHODS: A total of 60 monolithic Zr copings were cemented on Zr and Ti implant abutments with either a resin-modified glass-ionomer (RelyX Luting Plus Cement, 3M ESPE; Rx) or a zinc oxide eugenol cement (Temp-Bond, Kerr; Tb). These abutment-coping specimens were randomly divided into 12 groups based on laser application (vs control [C]), abutment type (Zr vs Ti), cement (Rx vs Tb), and storage condition (dry [D] vs saline water [W]). Er:YSGG laser was applied at 6 W, 30% water-60% air, and 20 Hz (300 mJ/pulse energy) postcementation following a defined pattern. The force required to remove all the cemented copings from their abutments was measured on a universal testing machine (Instron model 4204). Descriptive statistics, multi-factor analysis of variance, and post hoc Tukey honest significant difference tests (α = .05) were performed.

RESULTS: The mean peak force values at removal of the Zr abutment groups were 470.3 ± 151.33 N (ZrRxC), 161.7 ± 19.29 N (ZrRxD), 316.03 ± 95.24 N (ZrRxW), 103.27 ± 24.53 N (ZrTbC), 39.33 ± 6.21 N (ZrTbD), and 20.33 ± 6.45 N (ZrTbW); and for the Ti abutment groups were 349.80 ± 106.82 N (TiRxC), 84.63 ± 14.02 N (TiRxD), 177 ± 62.57 N (TiRxW), 54.77 ± 9.10 N (TiTbC), 22.67 ± 4.32 N (TiTbD), and 11.57 ± 2.30 N (TiTbW).

CONCLUSION: Within the limitations of this study, it can be concluded that Er:YSGG laser allows for easier removal of cemented Zr copings with lower removal forces, with Ti abutment groups requiring lower forces than Zr abutment specimens. No significant difference was seen between laser and control groups for Tb compared to Rx. Er:YSGG laser shows great clinical promise for predictable retrievability of cemented, monolithic Zr implant crowns, especially with stronger resin-based cement such as Rx. With further clinical evidence, this could be very useful for clinicians managing cement-retained implant crown complications.

PMID:33662063 | DOI:10.11607/ijp.6345

Phys Chem Chem Phys. 2021 Mar 4. doi: 10.1039/d1cp00031d. Online ahead of print.

ABSTRACT

Lanthanide elements have well-documented similarities in their chemical behavior, which make the valuable trivalent lanthanide cations (Ln3+) particularly difficult to separate from each other in water. In this work, we apply ab initio molecular dynamics simulations to compare the free energies (ΔGads) associated with the adsorption of lanthanide cations to silica surfaces at a pH condition where SiO- groups are present. The predicted ΔGads for lutetium (Lu3+) and europium (Eu3+) are similar within statistical uncertainties; this is in qualitative agreement with our batch adsorption measurements on silica. This finding is remarkable because the two cations exhibit hydration free energies (ΔGhyd) that differ by >2 eV, different hydration numbers, and different hydrolysis behavior far from silica surfaces. We observe that the similarity in Lu3+ and Eu3+ ΔGads is the result of a delicate cancellation between the difference in Eu3+ and Lu3+ hydration (ΔGhyd), and their difference in binding energies to silica. We propose that disrupting this cancellation at the two end points, either for adsorbed or completely desorbed lanthanides (e.g., via nanoconfinment or mixed solvents), will lead to effective Ln3+ separation.

PMID:33662085 | DOI:10.1039/d1cp00031d

Int J Prosthodont. 2021 Mar 3. doi: 10.11607/ijp.7367. Online ahead of print.

ABSTRACT

PURPOSE: To compare patient adaptation to and satisfaction with new complete dentures fabricated with a duplication construction protocol (DCP) using two different occlusal schemes, bilateral balanced (BBO) and lingualized (LO).

MATERIALS AND METHODS: Twenty complete denture wearers who received replacement DCP dentures participated in this study. Ten participants received complete dentures with a BBO scheme, and the other 10 received DCP dentures with an LO scheme. All of them evaluated their prostheses subjectively through the Oral Health Impact Profile-20 (OHIP-20) and the Complete Denture Satisfaction (CDS) questionnaires before treatment and at 3- and 6-month posttreatment intervals. The new prostheses were also normatively evaluated by recording the location and number of sore spots present at the scheduled early adjustment visits. Data were analyzed with nonparametric tests to identify differences in patient responses between groups and within each group at each evaluation interval point (α = .05).

RESULTS: The within-group comparisons revealed statistically significant improvement for both denture groups (P < .05), while the between-group comparisons did not record statistically significant differences at the overall evaluation period (P > .05). Significant within-group differences were recorded in the pain, functional limitation, and psychologic disability domains of the OHIP-20 questionnaire and the comfort, esthetics, and stability domains of the CDS questionnaire.

CONCLUSION: The patients’ adaptation to and satisfaction with newly constructed DCP dentures improved significantly for both BBO and LO denture groups throughout the evaluation period. The mean number of early adjustment visits was equal for both the BBO and LO denture groups.

PMID:33662056 | DOI:10.11607/ijp.7367

Int J Prosthodont. 2021 Mar 3. doi: 10.11607/ijp.7061. Online ahead of print.

ABSTRACT

PURPOSE: To assess the survival rate of 3 mol % yttria-stabilized tetragonal zirconia polycrystal (3Y-TZP) minimally invasive anterior and posterior single and double partial retainer fixed dental prostheses (PRFDPs).

MATERIALS AND METHODS: Twenty-three patients (18 women and 5 men, age range: 20 to 66 years) with single-tooth gaps received 28 3Y-TZP PRFDPs. Eight PRFDPs had two partial retainers and one pontic, two PRFDPs had two partial retainers and one pontic with a mesial cantilever, and 18 PRFDPs had one retainer and one cantilever. The abutment teeth were prepared following specific guidelines for all-ceramic restorations, considering existing direct restorations, carious processes, and occlusal conditions. The restorations were made of 3Y-TZP using CAD/CAM technology. Cementation was performed either conventionally, using resin-modified glass-ionomer (n = 6), or adhesively, using dual-polymerized resin cement (n = 22). Kaplan-Meier survival analysis was conducted. A P value of .05 was considered statistically significant.

RESULTS: During the observation period (5.92 ± 1.74 years, minimum = 2 years, maximum = 10 years), three debondings occurred, all in the two-retainer group and the mandible. The survival rates for the two types of intervention were different, with 100% for a single retainer and 70% for a double retainer, but without a significant difference (log-rank test χ²(1) = 0.200, P = .655).

CONCLUSION: The 3Y-TZP PRFDPs presented in this study showed no failure when bonded and not conventionally cemented. Therefore, they can be used in cases where implant therapy is not possible or indicated.

PMID:33662049 | DOI:10.11607/ijp.7061

Int J Prosthodont. 2021 Mar 3. doi: 10.11607/ijp.7193. Online ahead of print.

ABSTRACT

PURPOSE: To assess the retention and adaptation of milled and printed denture bases and to compare them to conventional ones.

MATERIALS AND METHODS: A total of 24 completely edentulous patients were selected. For each patient, three maxillary denture bases were constructed. Three groups were defined according to fabrication technique: group I = denture bases were constructed by a conventional technique; group II = denture bases were milled from prepolymerized blocks of polymethyl methacrylate; and group III = denture bases were fabricated by a 3D printing technique. A digital force gauge was used for measuring the retention of the denture bases intraorally, while Geomagic Control X 64 software was used to evaluate the adaptation of the denture bases with their corresponding master casts. Analysis of variance for repeated measures was used for comparison among the groups, followed by pairwise comparison with Bonferroni correction as a post hoc test. The significance level was set at α = .05.

RESULTS: Statistical analysis showed significant differences among the three groups regarding retention and adaptation. The highest values of retention and adaptation of denture bases were found in group II (milling group).

CONCLUSION: Within the limitations of this study, the following could be concuded: milled denture bases demonstrated better retention and adaptation than the conventional heat-polymerized and the printed denture bases; and printed denture bases showed better adaptation but similar retention to conventional heat-polymerized denture bases.

PMID:33662053 | DOI:10.11607/ijp.7193

Int J Prosthodont. 2021 Mar 3. doi: 10.11607/ijp.7280. Online ahead of print.

ABSTRACT

PURPOSE: To evaluate the efficacy of manual and machine-aided cleaning to remove matured plaque from removable partial dentures (RPD).

MATERIALS AND METHODS: A total of 32 patients with bilateral free-end saddle RPDs were included. The plaque was stained, and the RPD was photographed on all sides. One saddle was randomly allocated to manual cleaning, while the other was allocated to no cleaning. The patient manually cleaned the saddle by applying a denture brush and gel. The whole RPD was then cleaned with the aide of a machine using a rotating needle device. After each step, plaque dyeing and photographing were repeated. The plaque proportions (% pixel) were measured using special software. For statistical analysis, mixed models were used to adjust for baseline covariates, including plaque and surfaces, and to cover all time points.

RESULTS: The mean plaque area without cleaning at the fitting surface was higher than at the buccal/lingual surfaces (32.8% [95% CI: 28.1% to 36.4%] vs 15.3% [13.1% to 17.4%], respectively). Manual cleaning was not substantially better than no cleaning (4.6% [-0.1% to 9.2%] for the difference at fitting surfaces; disclaiming a substantial difference of > 10%; the difference found was even smaller at buccal/lingual surfaces). Machine-aided cleaning was substantially better than manual cleaning (16.1% [12.0% to 20.2%] for the difference at fitting surfaces and 7.3% [4.6% to 10.0%] at buccal/lingual surfaces). The combination of manual and machine-aided cleaning was not better than machine-aided cleaning alone (-0.2% [-2.6% to 2.1%] difference at fitting surface).

CONCLUSION: Manual cleaning is insufficient in removing matured denture plaque. Machine-aided cleaning is clearly superior to manual cleaning, especially at fitting surfaces.

PMID:33662054 | DOI:10.11607/ijp.7280

PLoS One. 2021 Mar 4;16(3):e0247700. doi: 10.1371/journal.pone.0247700. eCollection 2021.

ABSTRACT

INTRODUCTION: Chronic Respiratory Diseases (CRDs) are some of the most prevailing non-communicable diseases (NCDs) worldwide and cause three times higher morbidity and mortality in low- and middle-income countries (LMIC) than in developed nations. In Bangladesh, there is a dearth of data about the quality of CRD management in health facilities. This study aims to describe CRD service availability and readiness at all tiers of health facilities using the World Health Organization’s (WHO) Service Availability and Readiness Assessment (SARA) tool.

METHODS: A cross-sectional study was conducted from December 2017 to June 2018 in a total of 262 health facilities in Bangladesh using the WHO SARA Standard Tool. Surveys were conducted with facility management personnel by trained data collectors using REDCap software. Descriptive statistics for the availability of CRD services were calculated. Composite scores for facility readiness (Readiness Index ‘RI’) were created which included four domains: staff and guideline, basic equipment, diagnostic capacity, and essential medicines. RI was calculated for each domain as the mean score of items expressed as a percentage. Indices were compared to a cutoff of70% which means that a facility index above 70% is considered ‘ready’ to manage CRDs at that level. Data analysis was conducted using SPSS Vr 21.0.

RESULTS: It was found, tertiary hospitals were the only hospitals that surpassed the readiness index cutoff of 70%, indicating that they had adequate capacity and were ready to manage CRDs (RI 78.3%). The mean readiness scores for the other hospital tiers in descending order were District Hospitals (DH): 40.6%, Upazila Health Complexes (UHC): 33.3% and Private NGOs: 39.5%).

CONCLUSION: Only tertiary care hospitals, constituting 3.1% of sampled health facilities, were found ready to manage CRD. Inadequate and unequal supplies of medicine as well as a lack of trained staff, guidelines on the diagnosis and treatment of CRDs, equipment, and diagnostic facilities contributed to low readiness index scores in all other tiers of health facilities.

PMID:33661982 | DOI:10.1371/journal.pone.0247700

PLoS One. 2021 Mar 4;16(3):e0247958. doi: 10.1371/journal.pone.0247958. eCollection 2021.

ABSTRACT

BACKGROUND: Recently, the use of Yttrium-90 transarterial radioembolization in non-surgical hepatocellular carcinoma was suggested but the evidence supporting its use is unclear.

METHODS: We searched Medline, Embase, Web of Science and Cochrane CENTRAL from inception up to April 14, 2020 for randomized controlled trials comparing Y90-TARE to standard of care in non-surgical HCC patients. Our primary outcome was overall survival (OS). Our secondary outcomes were progression-free survival, time to progression, disease control rate, grade ≥3 adverse events and rates of gastro-intestinal ulcers. Hazard ratios (HR) and risk ratios (RR) with random-effects model were used for our analyses. The risk of bias of the included studies was assessed using Cochrane’s RoB 2 tool.

RESULTS: Of 1,604 citations identified, eight studies (1,439 patients) were included in our analysis. No improvement in overall survival were noted when Yttrium-90 transarterial radioembolization was compared to standard treatments (HR 0.99 [95% CI 0.81-1.21], 6 studies, I2 = 77.6%). However, Yttrium-90 transarterial radioembolization was associated with fewer grade ≥3 adverse events (RR 0.64 [95% CI 0.45-0.92], 7 studies, I2 = 66%). No difference was observed on other secondary outcomes.

DISCUSSION: In non-surgical HCC patients, Yttrium-90 transarterial radioembolization was not associated with significant effect on survival, progression-free survival, time to progression, disease control rate and the incidence of gastro-intestinal ulcers but was however associated with significantly lower rates of grade ≥3 adverse events. Further randomized controlled trials are warranted to better delineate optimal treatment.

PMID:33662011 | DOI:10.1371/journal.pone.0247958

PLoS One. 2021 Mar 4;16(3):e0246245. doi: 10.1371/journal.pone.0246245. eCollection 2021.

ABSTRACT

PURPOSE: To investigate the comparative efficacy of intense pulsed light (IPL) therapy alone with that of IPL plus meibomian gland expression (MGX) for meibomian gland dysfunction (MGD).

METHODS: This is a prospective randomized crossover clinical trial. Sixty patients were enrolled and randomly assigned to two groups. All of patients underwent four treatment sessions in total, which were two weeks apart. Group 1 underwent two sessions of IPL therapy with MGX, as well as two sessions of IPL alone. Group 2 received two sessions of IPL therapy alone, and two sessions of IPL therapy with MGX. The following parameters were measured at baseline (BL), 2 weeks after the second treatment session (FU1), and 2 weeks after the fourth treatment session (FU2): tearfilm break-up time (BUT), Oxford grade for corneal staining, meibomian gland expressibility (MGE), meibum quality (MQ), and ocular surface disease index (OSDI). The separate effect of MGX on improvement of MGD parameters was evaluated using generalized estimating equation (GEE).

RESULTS: The mean age of the participants was 57.52 ± 10.50 years. The BUT, Oxford grade, MGE, MQ, and OSDI of both groups improved significantly (from baseline) by the end of four treatment sessions (FU2 compared to BL; all p-values <0.05). The MGE and MQ significantly improved after the first and second treatment sessions (FU1 compare to BL; all p-values < 0.001). However, the improvement was not statistically significant after the third and fourth treatment sessions (FU2 compared to FU1; p-value of 0.388 for MGE and 0.645 for MQ in group 1, 0.333 for MGE and 0.333 for MQ in group 2). The IPL plus MGX therapy produced greater improvements in the BUT scores than did IPL therapy alone (p = 0.003 by GEE). In contrast, the Oxford grade, MGE, MQ, and OSDI were not influenced by the addition of MGX to IPL (p = 0.642, 0.663, 0.731, and 0.840, respectively by GEE).

CONCLUSION: IPL therapy effectively improves the subjective symptoms and objective ocular findings of MGD. MGX enhanced the improvement of BUT driven by IPL therapy. The meibomian gland function (MGE and MQ) recovers faster in response to IPL therapy than did the other parameters.

PMID:33662017 | DOI:10.1371/journal.pone.0246245