Category: Statistics

Phys Rev Lett. 2024 Jun 7;132(23):237401. doi: 10.1103/PhysRevLett.132.237401.

ABSTRACT

Continuous-state network spreading models provide critical numerical and analytic insights into transmission processes in epidemiology, rumor propagation, knowledge dissemination, and many other areas. Most of these models reflect only local features such as adjacency, degree, and transitivity, so can exhibit substantial error in the presence of global correlations typical of empirical networks. Here, we propose mitigating this limitation via a network property ideally suited to capturing spreading. This is the network correlation dimension, which characterizes how the number of nodes within range of a source typically scales with distance. Applying the approach to susceptible-infected-recovered processes leads to a spreading model which, for a wide range of networks and epidemic parameters, can provide more accurate predictions of the early stages of a spreading process than important established models of substantially higher complexity. In addition, the proposed model leads to a basic reproduction number that provides information about the final state not available from popular established models.

PMID:38905697 | DOI:10.1103/PhysRevLett.132.237401

Phys Rev Lett. 2024 Jun 7;132(23):238202. doi: 10.1103/PhysRevLett.132.238202.

ABSTRACT

Absorbing phase transitions (APTs) are widespread in nonequilibrium systems, spanning condensed matter, epidemics, earthquakes, ecology, and chemical reactions. APTs feature an absorbing state in which the system becomes entrapped, along with a transition, either continuous or discontinuous, to an active state. Understanding which physical mechanisms determine the order of these transitions represents a challenging open problem in nonequilibrium statistical mechanics. Here, by numerical simulations and mean-field analysis, we show that a quasi-2D vibrofluidized granular system exhibits a novel form of APT. The absorbing phase is observed in the horizontal dynamics below a critical packing fraction, and can be continuous or discontinuous based on the emergent degree of synchronization in the vertical motion. Our results provide a direct representation of a feasible experimental scenario, showcasing a surprising interplay between dynamic phase transition and synchronization.

PMID:38905681 | DOI:10.1103/PhysRevLett.132.238202

Phys Rev Lett. 2024 Jun 7;132(23):230401. doi: 10.1103/PhysRevLett.132.230401.

ABSTRACT

The combination of optical tweezer arrays with strong interactions-via dipole exchange of molecules and Van der Waals interactions of Rydberg atoms-has opened the door for the exploration of a wide variety of quantum spin models. A next significant step will be the combination of such settings with mobile dopants. This will enable one to simulate the physics believed to underlie many strongly correlated quantum materials. Here, we propose an experimental scheme to realize bosonic t-J models via encoding the local Hilbert space in a set of three internal atomic or molecular states. By engineering antiferromagnetic (AFM) couplings between spins, competition between charge motion and magnetic order similar to that in high-T_{c} cuprates can be realized. Since the ground states of the 2D bosonic AFM t-J model we propose to realize have not been studied extensively before, we start by analyzing the case of two dopants-the simplest instance in which their bosonic statistics plays a role-and compare our results to the fermionic case. We perform large-scale density matrix renormalization group calculations on six-legged cylinders, and find a strong tendency for bosonic holes to form stripes. This demonstrates that bosonic, AFM t-J models may contain similar physics as the collective phases in strongly correlated electrons.

PMID:38905661 | DOI:10.1103/PhysRevLett.132.230401

Phys Rev Lett. 2024 Jun 7;132(23):231003. doi: 10.1103/PhysRevLett.132.231003.

ABSTRACT

In this Letter, we demonstrate how to use the generalized δN formalism, which enables us to compute the evolution of all the large-scale fluctuations, including gravitational waves, solely by solving the evolution of the background homogeneous Universe. Using the Noether charge density, we derive an analytic formula which describes the mapping between the fluctuations at the horizon crossing and the sourced gravitational waves at the end of inflation. This formula can apply also to an inflation model with an anisotropic background. Using this formula, we discuss the condition for the nonvanishing linear polarization and the qualitative difference between single- and multigauge field models.

PMID:38905658 | DOI:10.1103/PhysRevLett.132.231003

Nurs Res. 2024 Jul-Aug 01;73(4):328-336. doi: 10.1097/NNR.0000000000000731. Epub 2024 Apr 13.

ABSTRACT

BACKGROUND: Chinese American immigrants have been underrepresented in health research partly due to challenges in recruitment.

OBJECTIVES: This study aims to describe recruitment and retention strategies and report adherence in a 7-day observational physical activity study of Chinese American immigrants with prior gestational diabetes during the COVID-19 pandemic.

METHODS: Foreign-born Chinese women aged 18-45 years, with a gestational diabetes index pregnancy of 0.5-5 years, who were not pregnant and had no current diabetes diagnosis were recruited. They wore an accelerometer for 7 consecutive days and completed an online survey. Multiple recruitment strategies were used: (a) culturally and linguistically tailored flyers, (b) social media platforms (e.g., WeChat [a popular Chinese platform] and Facebook), (c) near-peer recruitment and snowball sampling, and (d) a study website. Retention strategies included flexible scheduling and accommodation, rapid communications, and incentives. Adherence strategies included a paper diary and/or automated daily text reminders with a daily log for device wearing, daily email reminders for the online survey, close monitoring, and timely problem-solving.

RESULTS: Participants were recruited from 17 states; 108 were enrolled from August 2020 to August 2021. There were 2,479 visits to the study webpage, 194 screening entries, and 149 inquiries about the study. Their mean age was 34.3 years, and the mean length of U.S. stay was 9.2 years. Despite community outreach, participants were mainly recruited from social media (e.g., WeChat). The majority were recruited via near-peer recruitment and snowball sampling. The retention rate was 96.3%; about 99% had valid actigraphy data, and 81.7% wore the device for 7 days. The majority of devices were successfully returned, and the majority completed the online survey on time.

DISCUSSION: We demonstrated the feasibility of recruiting and retaining a geographically diverse sample of Chinese American immigrants with prior gestational diabetes during the COVID-19 pandemic. Recruiting Chinese immigrants via social media (e.g., WeChat) is a viable approach. Nonetheless, more inclusive recruitment strategies are needed to ensure broad representation from diverse socioeconomic groups of immigrants.

PMID:38905624 | DOI:10.1097/NNR.0000000000000731

Nurs Res. 2024 Jul-Aug 01;73(4):320-327. doi: 10.1097/NNR.0000000000000735. Epub 2024 Apr 13.

ABSTRACT

BACKGROUND: Research involvement and engagement is a vital aspect of nursing practice. However, research in dementia care remains limited compared to research focused on finding a cure, presenting a significant gap that specialist dementia nurses (Admiral Nurses) can help bridge by participating in research themselves and facilitating recruitment to research.

OBJECTIVES: This study aimed to assess the research involvement and support needs of Admiral Nurses and identify factors affecting their participation in research. This research is particularly timely as Dementia UK has launched its first research strategy, which necessitates strengthening research capacity within Admiral Nursing.

METHODS: We used a mixed methods convergent parallel synthesis design, simultaneously collecting quantitative and qualitative data. An online survey was conducted in January 2023, targeting current Admiral Nurses across the United Kingdom. The survey included questions addressing demographics, research experience, goals, barriers, facilitators, and support needs. Data analysis involved descriptive statistics, frequencies, univariate analyses, and thematic analysis.

RESULTS: A positive relationship was found between the highest level of academic achievement and current or previous research involvement, as well as interest in becoming involved in research in the future. Although most nurses recognized the importance of research, only half reported current or past research involvement, indicating a need for increased support. A lack of access and opportunities for peer discussion hindered engagement with research findings. Time constraints, lack of support, and low confidence were major barriers to research involvement. Support needs varied but included mentorship, coaching, and the potential for a community of practice for research.

DISCUSSION: This survey of Admiral Nurses sheds light on their research involvement, support needs, and barriers to participation. Recognizing the significance of research while identifying challenges and support requirements is crucial for enhancing research capacity among these specialized nurses. This study contributes valuable insights into the world of specialist dementia nursing and lays the foundation for future strategies to increase research engagement in this field.

PMID:38905623 | DOI:10.1097/NNR.0000000000000735

Nurs Res. 2024 Jul-Aug 01;73(4):278-285. doi: 10.1097/NNR.0000000000000743.

ABSTRACT

BACKGROUND: Hypertension rates have increased worldwide, with the most significant increase in morbidity and mortality observed among African Americans. Resilience is a potential factor influencing how individuals manage health-related challenges or self-management tasks for hypertension. Research is scarce related to resilience and self-management frameworks in African Americans with hypertension.

OBJECTIVES: We aimed to describe a conceptualized resilience framework and preliminary findings of the association among resilience precursors, stress response, hypertension self-management behaviors, and health outcomes in African Americans with hypertension.

METHODS: This cross-sectional, descriptive-correlational study included African American adults with hypertension, aged 25 years and older, recruited from an academic university and surrounding urban communities in the Midwest. Participants completed standardized, validated questionnaires to examine the association among resilience precursors, stress response, hypertension self-management behaviors, health-related quality of life (HRQOL), and blood pressure at baseline. Descriptive statistics were used to describe the sample demographic characteristics, whereas Pearson’s correlational and multiple regression analyses were conducted to determine the associations among the variables.

RESULTS: African Americans with hypertension (N = 30) were included in this preliminary study, with a mean age of 59.17 years; 66.7% were female. The mean systolic blood pressure was 136 (SD = 16.8) mmHg; the mean diastolic blood pressure was 78.1 (SD = 13) mmHg. Pearson’s correlation analysis revealed significant relationships between resilience precursors, stress response, hypertension self-management behaviors and capability, and health outcome components. Multiple regression analysis showed that poor perceived resilience significantly predicted depression. Low dispositional optimism and low perceived resilience were significant predictors of stress. Higher perceived resilience significantly predicted self-efficacy. Perceived stress was negatively and significantly associated with HRQOL. Finally, higher self-efficacy significantly predicted better HRQOL.

DISCUSSION: This study underscores the significant association between resilience, stress, self-management behaviors, and health outcomes in African Americans with hypertension. Further research with larger sample sizes and longitudinal designs is warranted to confirm and expand upon these findings.

PMID:38905621 | DOI:10.1097/NNR.0000000000000743

Rom J Intern Med. 2024 Jun 21. doi: 10.2478/rjim-2024-0022. Online ahead of print.

ABSTRACT

Introduction: Hepatocellular carcinoma (HCC) is a leading global cause of cancer-related deaths. Thermal ablation techniques, especially radiofrequency ablation (RFA) and microwave ablation (MWA), have become pivotal treatments for HCC. This systematic review and meta-analysis aim to compare these modalities, highlighting their efficacy, strengths, and limitations in treating HCC. Methods: A comprehensive literature search was conducted across major databases (PubMed, MEDLINE, Springer, ProQuest, EBSCOhost, Cochrane, and EMBASE) targeting studies on hepatocellular carcinoma with RFA and MWA. Heterogeneity analyses and pooled outcomes using random-effect models with were evaluated to compare both thermal ablation methods. Results: Nine studies, which consists of 368 patients underwent RFA and 387 patients underwent MWA, were included in review. The findings showed no significant differences in pooled analysis of volume of ablation, complete ablation rate, local tumor progression, survival rates, major complications, and adverse events. Subgroup analysis showed significantly higher risk of local tumor progression in RFA in African populations. Conclusion: No statistically significant difference was seen between outcomes across studies. MWA may offer a potential for longer therapeutic response with comparable risk of complications and adverse outcomes.

PMID:38905615 | DOI:10.2478/rjim-2024-0022

Gen Dent. 2024 Jul-Aug;72(4):62-71.

ABSTRACT

In this prospective pilot study, 84 patients with a history of poor oral hygiene were enrolled in an open-label, interventional, randomized controlled clinical trial. The aim was to provide preliminary clinical data on a new line of oral hygiene products containing a prebiotic and a paraprobiotic based on Lactobacillus plantarum. The recruitment rate and patient satisfaction were analyzed to estimate resources for the future primary study, and descriptive data on rebalancing of the oral microbiota were collected. The population was divided into 5 groups based on the products assigned to the patients: 1, delicate mint toothpaste (n = 20); 2, mint toothpaste (n = 12); 3, mint mouthwash (n = 20); 4, delicate mint toothpaste, mint mouthwash, and an antimicrobial toothbrush (n = 20); and 5, continued use of their usual oral care products and routine (control group; n = 12). The study duration was 28 days. All patients tolerated the products well, and there were no adverse events. The recruitment capability and procedures allowed for a realistic estimation for the future main trial. The products did not cause any changes in tooth color. The participants in group 4, who completed the treatment consisting of delicate mint toothpaste, mint mouthwash, and an antimicrobial toothbrush, reported the greatest reduction in gingival sensitivity (P ≤ 0.000; Wilcoxon signed rank test). Analysis with the Wilcoxon signed rank test revealed that all products induced a statistically significant decrease in plaque (P ≤ 0.002) and a reduction in gingival sensitivity (delicate mint toothpaste, P ≤ 0.005; mint toothpaste, P ≤ 0.015; and mint mouthwash, P ≤ 0.015). All products were effective in stabilizing the oral microbiota. The tested products showed an optimal safety profile and a statistically significant efficacy in reducing gingival sensitivity and plaque. They also stabilized the biodiversity of the oral microbiota, making it less susceptible to microbial fluctuations than the control group. Trial registration: ClinicalTrials.gov (NCT05999175).

PMID:38905608

Gen Dent. 2024 Jul-Aug;72(4):37-42.

ABSTRACT

The aim of this study was to identify and quantify artifacts produced by commonly used dental restorative materials in both standard and high-resolution cone beam computed tomographic imaging. In this in vitro study, 25 different dental materials were placed in holes (3 mm in diameter × 2 mm thick) prepared in the center of 10 × 10-mm polymethyl methacrylate plates. The specimens, along with a control plate prepared with an unfilled hole, were scanned at standard and high resolutions. The gray values (GVs) of the specimens were measured at 1-, 2-, 4-, and 8-mm distances from the material surfaces, and in 8 different directions, resulting in 32 measurements per specimen. The absolute value of the difference (ΔGV) between the GV of each measurement point on the specimen disc and the GV of the corresponding point on the control disc was considered to be the number of artifacts at that point. The median ΔGV of each material was calculated, and the materials were then ranked in terms of artifact formation using the Kruskal-Wallis test. At standard resolution, the greatest numbers of artifacts were caused by AH 26 root canal sealer and Heraenium S nickel-chromium alloy, and the fewest were caused by Whitepost DC #3 glass fiber post and ChemFil Superior glass ionomer cement. At high resolution, the greatest numbers of artifacts were found in amalgam (admix; SDI) and Heraenium S, and the fewest in Whitepost DC and GC Initial enamel porcelain. The median ΔGV values at standard and high resolutions were 46.0 and 57.0, respectively. High and standard resolutions were significantly different in terms of artifact formation (P = 0.001; Wilcoxon test). AH 26 sealer was the only material that demonstrated a statistically significant reduction in artifact formation at high resolution compared with standard resolution (P = 0.05; Wilcoxon test). The number of artifacts produced by dental materials at both resolutions decreased with an increasing distance from the surface of the material.

PMID:38905603