Category: Statistics

Sports (Basel). 2022 Jun 29;10(7):103. doi: 10.3390/sports10070103.

ABSTRACT

Organizational initiatives and researchers have argued for the importance of the natural outdoor environment (NOE) for promoting wellbeing. The main aim of this meta-analysis was to synthesize the existing literature to examine the effects of physical activity (PA) in the NOE on wellbeing in adults. The secondary aim was to explore whether wellbeing reported by adults differs as a function of PA context. Electronic databases (PubMed, ProQuest Nursing and Allied Health, PsycINFO, SPORTDiscus and Embase) were searched for English peer-reviewed articles published before January 2019. Inclusion criteria were: (1) healthy adults; (2) PA in the NOE; (3) the measurement of wellbeing; and (4) randomized control trials, quasi-experimental designs, matched group designs. To address the secondary aim, PA in the NOE was compared with that performed indoors. Risk of bias was assessed through the Effective Public Health Practice Project (EHPP) Quality Assessment Tool for Quantitative Studies. Primary studies meeting inclusion criteria for the main (n_studies = 19) and secondary (n_studies = 5) aims were analyzed and interpreted. The overall effect size for the main analysis was moderate (d = 0.49, p < 0.001; 95% CI = 0.33, 0.66), with the magnitude of effect varying depending on wellbeing dimension. Wellbeing was greater in PA in the NOE subgroup (d = 0.53) when compared with the indoor subgroup (d = 0.28), albeit not statistically significant (p = 0.15). Although physical activity in the NOE was associated with higher wellbeing, there is limited evidence to support that it confers superior benefits to that engaged indoors. Researchers are encouraged to include study designs that measure markers of wellbeing at multiple time points, greater consideration to diverse wellbeing dimensions and justify decisions linked to PA and NOE types.

PMID:35878114 | DOI:10.3390/sports10070103

Sports (Basel). 2022 Jun 28;10(7):101. doi: 10.3390/sports10070101.

ABSTRACT

(1) The purpose of this study was to examine the prevalence of the relative age effect (RAE) in the best young (10 to 15 years old) track and field athletes. (2) Hypothesis: The prevalence of the RAE in the best young track and field athletes of both genders will be evident in all age groups from 10 to 15 years old, which may be associated with the significant relationship between biological maturity, chronological age, and the development of physical qualities. (3) Materials and methods: In total, 1778 athletes volunteered for this study. The sample was based on the results of the best young athletes who participated in the final tournaments of the national competition “Shipovka Yunykh”(“Running spikes for young athletes”), which have been held since 1981. The sample group consisted of male and female athletes classified into specific age groups: 10 to 11 years old (n = 579), 12 to 13 years old (n = 600), and 14 to 15 years old (n = 599). Analysis was performed using Jamovi 1.8.1. The Chi-square test was used to compare the RAE between different groups. (4) Results: A wide distribution of the RAE was revealed both in the general sample and in boys and girls. The percentage of “early-born” athletes was 37.6% while only 12.3% were “late-born” athletes. The difference in the severity of the RAE may reflect the small sample of athletes from the fourth quartile, which was significantly less than the sample of boys from the fourth quartile (p = 0.04, OR 1.68, 95% CI 1.02-2.78). The RAE was also evident in all age groups of boys and girls, without any statistically significant differences in the severity (p > 0.05, Chi = 2.135, V = 0.02). In the 14- to 15-year-old male athletes group, the number of early-born compared to late-born athletes peaked. The RAE was most common amongst the most successful track and field athletes. Among the competition medalists during the analyzed time period, more than 50% of athletes were born in the first quarter and no athletes were born in the fourth quarter.

PMID:35878112 | DOI:10.3390/sports10070101

Law Hum Behav. 2022 Aug;46(4):313-323. doi: 10.1037/lhb0000489.

ABSTRACT

OBJECTIVE: In 2007, Congress changed the military’s sexual assault laws as part of an effort to improve sexual assault case processing. This study looked at the U.S. Army law enforcement investigative finding for every sexual assault reported to the Army from 2004 through June 2012, along with every nonsexual assault. Our objective was to measure whether the legal intervention affected the investigative findings made by Army law enforcement officers in sexual assault cases (penetrative, nonpenetrative, and combined) as compared to assault cases (aggravated, simple, and combined).

HYPOTHESES: We hypothesized that we would not find evidence that the legal intervention affected the rate of sexual assault cases labeled as “founded” by Army law enforcement, such that for the best-fitting time-series models, any difference in the residuals of the means before and after the intervention would not be statistically significant.

METHOD: We received data from the U.S. Army on all sexual assaults and nonsexual assaults from 2004 through June 2012. The data comprised 47,058 observations. We used time-series analysis with autoregressive integrated moving average modeling. The variable tracked over time was the ratio of the proportion of founded sexual assault cases to the proportion of founded nonsexual assault cases. We then conducted t tests of the means of the residuals before and after the legal intervention.

RESULTS: The difference in the means of the residuals before and after the intervention was not statistically significant for combined sexual assaults versus combined assaults, penetrative sexual assaults versus aggravated assaults, or nonpenetrative sexual assaults versus simple assaults.

CONCLUSIONS: This reform to sexual assault laws does not appear to have affected sexual assault case processing by U.S. Army law enforcement. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

PMID:35878107 | DOI:10.1037/lhb0000489

Gels. 2022 Jul 18;8(7):447. doi: 10.3390/gels8070447.

ABSTRACT

Industrial dye wastewater is one of the major water pollution problems. Adsorbent materials are promising strategies for the removal of water dye contaminants. Herein, we provide a statistical and artificial intelligence study to evaluate the adsorption efficiency of graphene oxide-based hydrogels in wastewater dye removal by applying Principal Component Analysis (PCA). This study aims to assess the adsorption quality of 35 different hydrogels. We adopted different approaches and showed the pros and cons of each one of them. PCA showed that alginate graphene oxide-based hydrogel (without polyvinyl alcohol) had better tolerance in a basic medium and provided higher adsorption capacity. Polyvinyl alcohol sulfonated graphene oxide-based hydrogels are suitable when higher adsorbent doses are required. In conclusion, PCA represents a robust way to delineate factors affecting hydrogel selection for pollutant removal from aqueous solutions.

PMID:35877532 | DOI:10.3390/gels8070447

Dent Traumatol. 2022 Jul 25. doi: 10.1111/edt.12776. Online ahead of print.

ABSTRACT

BACKGROUND/AIM: It is not known whether the mechanism of facial trauma influences the associated length of hospitalization. The aim of this study was to determine whether the mechanism of injury influenced the length of hospital stay (LOS) among pediatric patients who sustained facial fractures.

MATERIALS AND METHODS: This retrospective cohort study was completed using the Kids’ Inpatient Database (KID). The primary predictor variable was the mechanism of injury. The primary outcome variable was LOS. Linear regression was used to determine independent predictors of increased/decreased length of stay. A p-value of less than .05 was considered statistically significant.

RESULTS: The final sample consisted of 2865 subjects aged 12 years or younger who had suffered facial fractures. The most common mechanism of injury was motor vehicle accidents (MVA) (58.6%). Facial fractures due to MVA added 1.20 days (95% CI, 0.02, 2.38; p < .05) when compared to those due to a fall.

CONCLUSIONS: MVA significantly prolonged the LOS among young pediatric patients who sustained facial fractures, reflecting the exceptional amount of force involved. Having a chronic condition was also a significant factor for longer LOS. Four or more fractures also led to a longer LOS.

PMID:35877474 | DOI:10.1111/edt.12776

Eur J Investig Health Psychol Educ. 2022 Jul 21;12(7):870-881. doi: 10.3390/ejihpe12070063.

ABSTRACT

To make possible the inclusion of children with autism spectrum disorder (ASD) in mainstream settings, parental knowledge and attitudes towards the disorder play a key role between the home and the school setting. However, prior literature has not carried out an in-depth analysis of parents’ knowledge about ASD and their attitudes toward the inclusion of children with this diagnosis. This study examined the parental attitudes towards inclusion and knowledge about ASD. Participants were parents of children with ASD (n = 75), parents of children without ASD whose children had prior or current contact with peers with ASD (n = 44), and parents of children with no previous interactions with a peer with ASD (n = 51). The Attitudes of Regular Educators Towards Inclusion for Students with Autism Survey and the Autism Knowledge Questionnaire were filled out. Nonparametric statistical tests were used. Results showed that parents of children with ASD have better knowledge about this disorder and hold more favorable attitudes towards the inclusion of children with ASD than the other parents. These findings suggest that the benefits of inclusive schooling are limited to the school setting and do not appear to affect families of children without ASD.

PMID:35877463 | DOI:10.3390/ejihpe12070063

Eur J Investig Health Psychol Educ. 2022 Jul 13;12(7):802-813. doi: 10.3390/ejihpe12070059.

ABSTRACT

Background: Polycystic ovary syndrome (PCOS) is closely related to various adverse cardiovascular manifestations and increased cardiovascular risk. However, atrial fibrillation (AF) development and atrial conduction abnormalities have not been thoroughly studied in patients with PCOS. Methods: This meta-analysis (CRD42021261375) was conducted in accordance with the PRISMA guidelines. Our aim was to investigate associations between PCOS and disorders in atrial conduction parameters linked with an increased risk for AF occurrence. Results: Five cohort studies with aggregate data on 406 adult women (229 with PCOS and 177 age-matched without PCOS) were included in this analysis. Our results showed a significantly increased mean difference in P-wave maximum duration (+7.63 ± 7.07 msec; p &lt; 0.01) and P-wave dispersion (+11.42 ± 5.22 msec; p = 0.03) of patients with PCOS compared to healthy women. The mean difference in P-wave minimum duration (-2.22 ± 2.68 msec; p = 0.11) did not reach the statistical threshold between the compared groups. Echocardiographic measurements of atrial electromechanical delay (AED) also indicated a statistically significant mean difference in favour of the PCOS group in all assessed parameters, except for atrial electromechanical coupling (PA) in the tricuspid annulus. Particularly, PCOS was associated with increased lateral PA, septal PA, inter- and intra-AED durations (mean difference: +17.31 ± 9.02 msec; p &lt; 0.01, +11.63 ± 7.42 msec; p &lt; 0.01, +15.31 ± 9.18 msec; p &lt; 0.01, +9.31 ± 6.85 msec; p &lt; 0.01, respectively). Conclusions: PCOS is strongly associated with alterations in several electrocardiographic and echocardiographic parameters indicating abnormal atrial conduction. Therefore, PCOS could be considered as a causal or triggering factor of AF. Larger studies are needed to confirm these results and investigate direct associations between PCOS and AF.

PMID:35877459 | DOI:10.3390/ejihpe12070059

Curr Issues Mol Biol. 2022 Jul 5;44(7):3053-3074. doi: 10.3390/cimb44070211.

ABSTRACT

The aim of the study was to determine the metabolic characteristics of saliva depending on the molecular biological subtype of breast cancer, as well as depending on the expression levels of HER2, estrogen receptors (ER), and progesterone receptors (PR). The study included 487 patients with morphologically verified breast cancer and 298 volunteers without breast pathologies. Saliva samples were obtained from all patients strictly before the start of treatment and the values of 42 biochemical indicators were determined. It has been established that the saliva of healthy volunteers and patients with various molecular biological subtypes of breast cancer differs in 12 biochemical indicators: concentrations of protein, urea, nitric oxide, malondialdehyde, total amino acid content, and activity of lactate dehydrogenase, alkaline phosphatase, gamma-glutamyltransferase, catalase, amylase, superoxide dismutase, and peroxidases. The saliva composition of patients with basal-like breast cancer differs from other subtypes in terms of the maximum number of indicators. Changes in biochemical indicators indicated an increase in the processes of lipid peroxidation and endogenous intoxication and a weakening of antioxidant protection, which correlates with the severity of the disease and the least favorable prognosis for this subtype of breast cancer. An analysis was made of the individual contribution of the expression level of HER2, estrogen, and progesterone receptors to changes in the biochemical composition of saliva. The HER2 (-)/HER2 (+) group, which should be considered as a single group, as well as ER-positive breast cancer, differ statistically significantly from the control group. For ER/PR-positive breast cancer, a more favorable ratio of saliva biochemical indicators was also noted compared to ER/PR-negative breast cancer.

PMID:35877435 | DOI:10.3390/cimb44070211

Curr Issues Mol Biol. 2022 Jun 29;44(7):2903-2914. doi: 10.3390/cimb44070200.

ABSTRACT

There are multiple lines of evidence for the existence of communication between the central nervous system (CNS), gut, and intestinal microbiome. Despite extensive analysis conducted on various neurological disorders, the gut microbiome was not yet analyzed in neuroinfections. In the current study, we analyzed the gut microbiome in 47 consecutive patients hospitalized with neuroinfection (26 patients had viral encephalitis/meningitis; 8 patients had bacterial meningitis) and in 20 matched for age and gender health controls. Using the QIIME pipeline, 16S rRNA sequencing and classification into operational taxonomic units (OTUs) were performed on the earliest stool sample available. Bacterial taxa such as Clostridium, Anaerostipes, Lachnobacterium, Lachnospira, and Roseburia were decreased in patients with neuroinfection when compared to controls. Alpha diversity metrics showed lower within-sample diversity in patients with neuroinfections, though there were no differences in beta diversity. Furthermore, there was no significant change by short-term (1-3 days) antibiotic treatment on the gut microbiota, although alpha diversity metrics, such as Chao1 and Shannon’s index, were close to being statistically significant. The cause of differences between patients with neuroinfections and controls is unclear and could be due to inflammation accompanying the disease; however, the effect of diet modification and/or hospitalization cannot be excluded.

PMID:35877424 | DOI:10.3390/cimb44070200

Curr Issues Mol Biol. 2022 Jun 29;44(7):2879-2886. doi: 10.3390/cimb44070198.

ABSTRACT

Chronic inflammation and cancer stem cells are known risk factors for tumorigenesis. The aetiology of hepatocellular carcinoma (HCC) involves a multistep pathological process that is characterised by chronic inflammation and hepatocyte damage, but the correlation between HCC, inflammation and cancer stem cells remains unclear. In this study, we examined the role of hepatic progenitor cells in a mouse model of chemical-induced hepatocarcinogenesis to elucidate the relationship between inflammation, malignant transformation and cancer stem cells. We used diethylnitrosamine (DEN) to induce liver tumour and scored for H&E and reticulin staining. We also scored for immunohistochemistry staining for OV-6 expression and analysed the statistical correlation between them. DEN progressively induced inflammation at week 7 (40%, 2/5); week 27 (75%, 6/8); week 33 (62.5%, 5/8); and week 50 (100%, 12/12). DEN progressively induced malignant transformation at week 7 (0%, 0/5); week 27 (87.5%, 7/8); week 33 (100%, 8/8); and week 50 (100%, 12/12). The obtained data showed that DEN progressively induced high-levels of OV-6 expression at week 7 (20%, 1/5); week 27 (37.5%, 3/8); week 33 (50%, 4/8); and week 50 (100%, 12/12). DEN-induced inflammation, malignant transformation and high-level OV-6 expression in hamster liver, as shown above, as well as applying Spearman’s correlation to the data showed that the expression of OV-6 was significantly correlated to inflammation (p = 0.001) and malignant transformation (p &lt; 0.001). There was a significant correlation between the number of cancer stem cells, inflammation and malignant transformation in a DEN-induced model of hepatic carcinogenesis in the hamster.

PMID:35877422 | DOI:10.3390/cimb44070198