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Nevin Manimala Statistics

Predicting Medication Adherence in Schizophrenia: The Role of Reminiscence Functions and the Moderating Effect of Metacognitive Beliefs on the Effect of Insight on Medication Adherence

Issues Ment Health Nurs. 2026 Mar 6:1-13. doi: 10.1080/01612840.2026.2636099. Online ahead of print.

ABSTRACT

In the context of schizophrenia, it has been previously held that the more insight a patient has about their condition, the more likely they are to adhere to their medication regimen more closely. However, insight alone may not be enough. Metacognitive beliefs (ideas and assumptions about their own cognitive processes, such as thinking, memory, and attention) serve as a critical factor impacting this relationship, given their association with both improved medication adherence and increased insight. Another key component of insight is one’s ability to reminisce. However, no existing studies have explored the link between reminiscence and medication adherence, which could inform the development of appropriate patient interventions. This study aimed to examine the moderating effect of metacognitive beliefs on the relationship between insight and medication adherence and assess the prediction of medication adherence based on reminiscence functions in a sample of patients hospitalized for schizophrenia. This cross-sectional study employed a convenience sampling method to collect data from 224 patients hospitalized for schizophrenia, as administered through interviews with clinical staff. While reminiscence functions were not directly associated with improved medication adherence, this could be due to their relationship with other sociodemographic predictors in the model. It was shown, however, that higher levels of metacognitive beliefs, dominated by dysfunctional metacognitive beliefs, were significantly associated with a reduced effect of insight on medication adherence (p = 0.016). Patients with high levels of dysfunctional metacognitive beliefs struggle with connecting awareness of their condition with the necessity of adhering to medication. Mental health nurses should consider overarching assessments of metacognitive beliefs to further understand medication adherence and its relationship with patient insight.

PMID:41790431 | DOI:10.1080/01612840.2026.2636099

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Nevin Manimala Statistics

Safety and feasibility of tubeless PCNL without urinary catheter or retrograde intubation under paravertebral block

Int Urol Nephrol. 2026 Mar 6. doi: 10.1007/s11255-026-05082-8. Online ahead of print.

ABSTRACT

OBJECTIVE: To evaluate the feasibility and safety of omitting postoperative urinary catheter placement in patients undergoing percutaneous nephrolithotomy (PCNL) under paravertebral block (PVB) anesthesia without retrograde catheterization.

METHODS: This retrospective study analyzed 197 eligible patients selected from an initial cohort of 248. All patients received PCNL under PVB. They were divided into two groups based on postoperative catheterization: Group 1 (without urinary catheter, n = 97) and Group 2 (with urinary catheter, n = 100). To minimize confounding factors, propensity score matching was performed based on the number of access tracts, resulting in two groups: Group A (without urinary catheter, n = 90) and Group B (with urinary catheter, n = 90). Preoperative baseline characteristics, perioperative parameters, and postoperative complications were compared between the groups.

RESULTS: No significant differences were observed in age, gender, body mass index (BMI), comorbidities, stone characteristics, or preoperative laboratory findings between the two groups (P > 0.05), indicating comparability. Regarding surgical efficacy and safety, there were no statistically significant differences in operative time, blood loss, number of access tracts, postoperative hemoglobin drop, inflammatory marker changes, or initial stone-free rate (P > 0.05). Group A showed superior outcomes in several aspects: lower visual analog scale (VAS) pain scores (P < 0.001), shorter postoperative hospital stay [3.00 (3.00, 4.00) vs. 4.00 (3.00, 4.00) days, P < 0.001], lower incidence of postoperative urinary tract infection (2/90 vs. 10/90, P = 0.017), and lower overall postoperative complication rate (9/90 vs. 25/90, P < 0.002).

CONCLUSION: For appropriately selected patients undergoing PCNL under PVB without retrograde catheterization, omitting the postoperative urinary catheter is a safe practice. This approach is associated with reduced postoperative pain, shorter hospitalization, and merits clinical consideration under standardized perioperative management.

PMID:41790419 | DOI:10.1007/s11255-026-05082-8

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Nevin Manimala Statistics

Beyond the snellen chart: exploring the clinical potential of sweep visual evoked potentials for visual acuity measurement

Doc Ophthalmol. 2026 Mar 6. doi: 10.1007/s10633-026-10091-0. Online ahead of print.

ABSTRACT

PURPOSE: To evaluate the agreement between Snellen visual acuity (VA) and sweep visual evoked potential (sVEP) VA in individuals with normal vision and assess sVEP variability and reproducibility across multiple test sessions.

METHODS: Thirty-nine healthy participants (78 eyes) underwent Snellen and sVEP VA testing. Ten participants (20 eyes) also underwent sVEP testing twice daily (morning and afternoon) on three separate days (120 total recordings). and Snellen VA measurements showed strong agreement, with a mean absolute difference of 0.03 LogMAR (less than one Snellen line). Forty of 78 eyes had differences within one Snellen line, while the largest discrepancy reached four lines. Statistical analysis (P = 0.201) indicated no significant difference between the two methods. sVEP reproducibility was also high, with no significant variation between morning and afternoon recordings (P = 0.67), confirming its stability as a clinical tool.

CONCLUSION: sVEP provides objective and reproducible VA measurements comparable to Snellen VA, suggesting its potential as an alternative clinical assessment tool, particularly for patients with communication challenges, cognitive impairments, or suspected malingering vision loss.

PMID:41790402 | DOI:10.1007/s10633-026-10091-0

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Nevin Manimala Statistics

Duolingo-inspired pretesting with words and pictures improves vocabulary learning

Cogn Res Princ Implic. 2026 Mar 6;11(1):20. doi: 10.1186/s41235-026-00708-y.

ABSTRACT

Contemporary language learning applications such as Duolingo and Rosetta Stone often introduce vocabulary through guessing-with-feedback exercises in which learners match words and pictures. We investigated whether that process might yield a pretesting effect-that is, the phenomenon where guessing with correct answer feedback (pretesting) enhances memory. Across four experiments, adult online learners engaged in multiple-choice pretesting to learn Spanish word translations shown in word-image (Experiments 1-2) or image-word (Experiments 3-4) format. Relative to a read-only condition, pretesting yielded statistically significant performance improvements on subsequent cued recall (Cohen’s d = 0.18-0.40) and, in most cases, multiple-choice tests (d = 0.25-0.67), regardless of whether test formats were separately presented or intermixed. Participants also reported preferring pretesting over reading for learning second-language vocabulary, especially for word-image learning. Together, these findings extend the pretesting effect to visual and verbal materials, offering theoretical insights and substantiating word-image and image-word guessing-based approaches of language learning.

PMID:41790401 | DOI:10.1186/s41235-026-00708-y

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Nevin Manimala Statistics

How is mental health associated with dental health in refugee children?

Eur Arch Paediatr Dent. 2026 Mar 6. doi: 10.1007/s40368-026-01188-w. Online ahead of print.

ABSTRACT

BACKGROUND: Refugee families often arrive in Europe full of hope after facing many challenges. It is known that a significant proportion of them suffer from post-traumatic stress disorder (PTSD) and that this is associated with bad health status, including oral health in adults. While it is known that refugee children have poor dental health, it remains unclear if this is related to their mental health. We aimed to find out if children’s PTSD status was associated with their dental health. We further examined if parental mental health is associated with children’s dental health.

METHODS: The study is part of the German INterCuLtUral Child DevelopmEnt Studies (INCLUDE). Dental and psychological examination of n = 44 children between 1.5 and 6 years was conducted. Dental health was assessed with dmft value and O’Leary Plaque Index (PI). The Child and Adolescent Trauma Screening was applied to test for PTSD symptoms in children. Parental mental health was assessed with the refugee health screener (RHS). Descriptive analyses and multiple linear regression were performed to test the association between child’s PTSD and dental health with parental mental health.

RESULTS: Mean dmft value was 4.98 (± 3.69), mean PI was 40.92 (± 14.76). PTSD was detected in 30% of the children. There were no statistically significant differences between children with and without PTSD symptoms pertaining dental health. Linear regression yielded child’s age and parental RHS score to be positively associated with child’s dmft value.

CONCLUSIONS: Children’ had poor dental health status, regardless of the presence of PTSD. Parental mental health was associated with child dental health. Interventions and programs for refugee children should consider parental mental health as well.

PMID:41790396 | DOI:10.1007/s40368-026-01188-w

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Nevin Manimala Statistics

Systematic data analysis of inpatient acute geriatric wards in Austria in 2024

Wien Med Wochenschr. 2026 Mar 6. doi: 10.1007/s10354-026-01134-x. Online ahead of print.

ABSTRACT

BACKGROUND AND OBJECTIVE: Inpatient acute geriatric wards provide care for older patients with multiple morbidities who require treatment due to acute events, with a focus on maintaining or restoring independence. Geriatric patients need treatment that takes into account medical, functional, psychological, and social aspects. In 2005, the Association for Quality in Geriatrics and Gerontology (QiGG) developed a uniform documentation standard for process control and quality assurance in acute geriatric inpatient care, which is used by many acute geriatric wards in Austria. Aim of this study was to conduct a reliable, systematic analysis of data collected in 2024 from acute geriatric wards in Austria, taking into account gender-specific differences, in order to provide transparency on the geriatric care situation and thereby generate a basis for scientific analysis, evidence-based planning, and managing of future care structures.

METHODS: Patient characteristics, therapeutic services, length of stay, and geriatric assessment parameters (self-care ability, mobility, social history, polypharmacy) were analyzed from data of 7545 patients from 15 acute geriatric wards in Austria in 2024. Data were collected using the digital Benchmarking and Reporting System CDS-BARS, and analyzed using descriptive statistics.

RESULTS: More than 50% of the patients were admitted to acute geriatric wards within 2 weeks of the acute event. Overall, almost twice as many women as men were admitted. On average, patients had around 7.6 functional impairments upon admission. Most patients remained in the acute geriatric ward for 15 to 21 days and achieved a demonstrable and quantifiable improvement in their self-care abilities and mobility during their stay. A total of 90.5% of patients who lived at home before their stay returned home afterwards.

CONCLUSION: This study underscores the importance of acute geriatric wards in an aging society and the need for continuous development of acute geriatric structures.

PMID:41790386 | DOI:10.1007/s10354-026-01134-x

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Nevin Manimala Statistics

Prognostic drivers beyond anatomy: towards tailored surgical management in descending necrotizing mediastinitis

Updates Surg. 2026 Mar 6. doi: 10.1007/s13304-026-02592-z. Online ahead of print.

ABSTRACT

The management of descending necrotizing mediastinitis (DNM) is challenging due to diagnostic delays and a lack of consensus on optimal therapeutic. While the Endo classification describes anatomical extent, its link to patient outcomes remains unclear. This study aimed to evaluate the prognostic utility of the Endo classification and identify key factors predictive 90-day mortality and prolonged hospitalization. We performed a retrospective, single-center cohort study spanning 2015-2025 that included 52 consecutive patients with descending necrotizing mediastinitis who were managed surgically. Demographic characteristics, clinical features, Endo classification, operative approaches, and postoperative outcomes were systematically evaluated. Univariable regression and correlation analyses were applied to determine factors associated with 90-day mortality and length of postoperative hospital stay. The cohort (median age 54 years, 65.4% male) had an 11.5% 90-day mortality rate. The Endo classification guided surgical approach but was not significantly associated with mortality or hospital stay. Instead, preoperative hypoalbuminemia (odds ratio (OR) 1.29 per 1 g/L decrease, p = 0.032), postoperative white blood cell count (OR 1.40 per × 109 decrease, p = 0.046) and odontogenic of infection (OR 0.122, p = 0.026) were significant risk factors for mortality. A shorter symptom-to-diagnosis interval (r = – 0.386, p = 0.008) and the presence of empyema (median stay 34.5 vs. 25.5 days, p = 0.020) were independently associated with a longer postoperative hospital stay. In lower mediastinitis (Types IIA-C), a thoracic approach was associated with a lower incidence of the composite outcome (reoperation/death) compared to a transcervical approach (9.1% vs. 33.3%), though this difference was not statistically significant (p = 0.227). In DNM, physiological reserve and disease tempo are more powerful prognostic indicators than anatomical extent alone. A fulminant presentation and nutritional status are key prognostic indicators. These findings support a management paradigm that integrates early physiological optimization with tailored surgical intervention and postoperative care based on disease extent.

PMID:41790373 | DOI:10.1007/s13304-026-02592-z

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Nevin Manimala Statistics

Correction: Assessing the Use of Medical Insurance Claims and Electronic Health Records to Measure COVID‑19 Vaccination During Pregnancy

Drug Saf. 2026 Mar 6. doi: 10.1007/s40264-026-01661-x. Online ahead of print.

NO ABSTRACT

PMID:41790353 | DOI:10.1007/s40264-026-01661-x

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Nevin Manimala Statistics

Environmental metal exposure and autism spectrum disorder: spatial analysis of exposure patterns and associated risk among children in Alabama

Environ Sci Pollut Res Int. 2026 Mar 6. doi: 10.1007/s11356-026-37566-6. Online ahead of print.

ABSTRACT

Autism spectrum disorder (ASD) is a neurodevelopmental condition with increasing rates of diagnosis and potential links to environmental exposures. Metals are known neurotoxicants that may exacerbate ASD symptom presentation. Our study focused on children aged 3-10 years clinically diagnosed with ASD who have lived in Alabama since birth. Spatial analysis assessed metal distribution and clustering patterns, and Spearman correlation was used to evaluate associations between air toxic metals and ASD symptom presentation. Spatial analysis of airborne metals across Alabama showed considerable spatial variability and hot spots, mostly in central Alabama and surrounding counties. ASD symptom presentation showed moderate positive correlation with cadmium, chromium, and lead, weak positive correlation with manganese, and weak negative correlation with mercury. Proximity and statistical analysis showed 73% of the participants lived within 5 km of an industrial site; those living more than 10 km away had much lower ASD scores, and proximity was a strong predictor of ASD symptoms. Our findings show that children in Alabama may be exposed to multiple air toxic metals at different exposure windows, and industrial emissions and residential proximity to pollution sources are potential environmental contributors to increased ASD symptom presentation.

PMID:41790349 | DOI:10.1007/s11356-026-37566-6

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Nevin Manimala Statistics

Spatial and temporal assessment of heavy metal contamination in urban soils of Mosul post war (2022-2023): environmental implications and risk evaluation

Environ Sci Pollut Res Int. 2026 Mar 6. doi: 10.1007/s11356-026-37536-y. Online ahead of print.

ABSTRACT

Soil contamination with heavy metals remains a major environmental concern in post-conflict Mosul City, posing risks to agriculture, ecosystems, and human health. This study investigated seasonal and interannual variations in cadmium (Cd), lead (Pb), zinc (Zn), chromium (Cr), and nickel (Ni), along with key soil properties (pH, electrical conductivity, and salinity), across urban soils during 2022-2023 by applying multivariate statistics and ArcGIS-based spatial analysis. Severe contamination was identified in 39.47% of the study area (S3, S4, and S7), while high contamination affected an additional 40.09% (S6 and S8); the remaining 20.43% (S1, S2, and S5) showed moderate contamination. Soil pH remained relatively stable, whereas electrical conductivity, salinity, and heavy metals particularly Pb, Zn, Cr, and Ni exhibited higher variability. Strong inter-metal correlations and principal component analysis indicated dominant anthropogenic influences, with heavy metals forming one principal component and EC-salinity another. Seasonal variations were evident in 2022, most likely associated with rainfall-driven leaching, but were negligible in 2023 under drier conditions. Spatial patterns reflected the combined influence of soil properties, climatic conditions, and human activities. These findings highlight the persistence of soil contamination in post-conflict Mosul and underscore the need for immediate remediation in high-risk zones, continued monitoring in moderately contaminated areas, and adaptive land management practices to reduce environmental and health risks. The integrated multivariate-spatial framework offers a transferable approach for assessing soil contamination in conflict-affected urban environments.

PMID:41790348 | DOI:10.1007/s11356-026-37536-y