Int J Environ Res Public Health. 2025 Jul 23;22(8):1165. doi: 10.3390/ijerph22081165.
ABSTRACT
In the original publication […].
PMID:40838296 | DOI:10.3390/ijerph22081165
An Sist Sanit Navar. 2025 Aug 21;48(2):e1109. doi: 10.23938/ASSN.1109.
ABSTRACT
BACKGROUND: This study aimed to evaluate the effects of nursing quality control combined with intensified psychological care on negative emotions and health outcomes in patients undergoing blood purification.
METHODS: Patients who underwent blood purification at the Affiliated Hospital of Jiangnan University (China) from January 2021 to December 2023 were enrolled and assigned to either a control or an intervention group using a random number table. Both groups received standard care, while the intervention group additionally received nursing quality control and intensified psychological care. Outcomes compared between groups included negative emotions (assessed by the Hamilton Anxiety Scale and Hamilton Depression Scale scores), quality of life (SF-36), treatment adherence, and complication rates.
RESULTS: Prior to the treatment, both groups (150 patients in each) were comparable in the Hamilton Anxiety Scale, the Hamilton Depression Scale, and SF-36 scores. After the treatment, the intervention group showed significantly greater reduction in the Hamilton Anxiety Scale (15.89 vs. 7.19) and Hamilton Depression Scale (12.22 vs. 4.74) scores, and greater improvements in SF-36 scores, particularly in physical functioning (37.99 vs. 22.61and) and mental health (34.48 vs. 18.95). Moreover, treatment adherence was significantly higher in the intervention group (98.67% vs 70%), while the complication rate was markedly lower (10% vs. 35.33%). All differences were statistically significant (p < 0.001).
CONCLUSIONS: Nursing quality control combined with intensified psychological care significantly improves negative emotional states and quality of life in patients undergoing blood purification, while also enhancing treatment adherence and reducing the incidence of complications.
PMID:40838287 | DOI:10.23938/ASSN.1109
Spine (Phila Pa 1976). 2025 Aug 21. doi: 10.1097/BRS.0000000000005464. Online ahead of print.
ABSTRACT
STUDY DESIGN: Modified Delphi consensus survey.
OBJECTIVE: To survey expert opinion on postoperative return-to-sport (RTS) decisions in athletes requiring cervical spine surgery.
SUMMARY OF BACKGROUND DATA: Postoperative sport participation recommendations for athletes requiring cervical spine surgery are lacking, and management of these athletes remains challenging.
METHODS: A cross-sectional, modified Delphi consensus survey investigating RTS decisions in athletes requiring various cervical spine operations was undertaken. A panel of neurosurgery/orthopedic spine surgeons with sport expertise was identified from the United States and Australia. Single and multi-level cervical spine surgical conditions studied included: anterior cervical discectomy and fusion (ACDF), cervical laminectomy and laminoplasty, posterior cervical fusion, occipito-cervical fusion, C1 fracture, and C1-C2 fusion. A 2×2 scheme was used to classify sport risk based on impact forces and frequency: low impact/low frequency, low impact/high frequency, high impact/low frequency, and high impact/high frequency. Consensus was a-priori defined at ≥70%. Descriptive statistics were performed.
RESULTS: Of the 34 sports spine surgeons invited (56% neurosurgeons and 44% orthopedic surgeons), survey completion was 100%. Consensus was achieved to recommend return to high impact/high frequency sport for individuals with 1-level ACDF, 1-level cervical laminectomy, 1-level posterior cervical fusion, and for a healed C1 fracture treated with open reduction and internal fixation. For individuals with a healed occipito-cervical fusion, consensus was achieved to recommend return to low impact/low frequency sport.
CONCLUSIONS: Consensus was achieved to recommend return to high impact/high frequency sport after surgical treatment of a variety of cervical pathologies in athletes. Certain situations received consensus recommendations to return to low impact/low frequency sport, while many others did not reach a consensus. These results provide useful data that can help spine surgeons navigate challenging postoperative RTS decisions.
PMID:40838273 | DOI:10.1097/BRS.0000000000005464
Front Psychiatry. 2025 Aug 5;16:1636838. doi: 10.3389/fpsyt.2025.1636838. eCollection 2025.
ABSTRACT
BACKGROUND: The prevalence of late-life depression (LLD) is high, and its most dangerous, serious, and fatal comorbidity is suicide. Therefore, the present study systematically investigates the risk factors for suicide in individuals with LLD, offering empirical support for the development of preventive interventions against suicidal behavior.
METHODS: PubMed, Web of Science, the Cochrane Library, PsycInfo, CNKI, Wan Fang Data, VIP, and CBM databases were searched from the inception of each database to February 2025 to identify observational studies of risk factors for suicide in LLD patients. The Newcastle-Ottawa Scale (NOS) and the Agency for Healthcare Research and Quality (AHRQ) were used to ensure study quality. Stata 18.0 software was used to perform a meta-analysis and sensitivity analysis to compute the pooled odds ratio.
RESULTS: A total of 12 studies (eight case-control, two cross-sectional, and two longitudinal studies), with a quality level of medium or above, were included in the analysis. Depression severity (OR = 3.485, 95% CI: 1.385 to 8.769, P = 0.008) was identified as a significant risk factor for suicide in LLD. The age of onset (OR = 0.969, 95% CI: 0.905 to 1.039, P = 0.378) was not statistically significant for the risk of suicide in LLD. The descriptive analysis revealed that suicidal ideation, educational level, N3 sleep duration, odor identification dysfunction, alcohol drinking history, cognitive function, history of major trauma, history of suicide attempts, and high-density lipoprotein were associated with an increased suicide risk in LLD.
CONCLUSION: Our meta-analysis has revealed a variety of factors influencing suicide risk in LLD patients. Clinical staff should strengthen the assessment and screening of risk factors and take timely intervention and targeted treatment to reduce the risk of suicide in LLD.
SYSTEMATIC REVIEW REGISTRATION: https://www.crd.york.ac.uk/prospero/, identifier CRD420251040029.
PMID:40838257 | PMC:PMC12362716 | DOI:10.3389/fpsyt.2025.1636838
Front Psychiatry. 2025 Aug 5;16:1548282. doi: 10.3389/fpsyt.2025.1548282. eCollection 2025.
ABSTRACT
OBJECTIVE: Depression is a significant global public health issue, and Breakfast habits may be related to its onset. This study conducted a meta-analysis of previous studies to analyze the correlation between breakfast and depression, comprehensively evaluated the association between skipping breakfast and the risk of depression, and explored the potential sources of heterogeneity.
METHODS: PubMed, Embase, and Web of Science databases were searched(the retrieval time limit for all was from the establishment of the databases to September 1, 2024), English documents were selected from the databases(the research type was observational study), and then the data was extracted and the Newcastle-Ottawa Scale(NOS) was evaluated for data analysis of the selected studies. This study followed the guidelines of the Preferred Reporting Project (PRISMA) and Prospero Registration Agreement. The mixed-effects model combines the maximum adjusted estimates and measures heterogeneity using the I2 statistic. Sensitivity analysis verified the robustness of the analysis and assessed publication bias.
RESULTS: A meta-analysis of 12 literatures showed that skipping breakfast was positively correlated with the incidence of depression (RR=1.83, [95%CI 1.52-2.20], τ2: 0.09, I2: 96.37%). Egger test was conducted on the relationship between skipping breakfast and depression, P=0.067 > 0.05, and the result suggested that there was no significant publication bias. Subgroup analysis indicates that current studies in different regions still have deficiencies, and the analysis shows that the occurrence of depression is associated with gender and the sample size of the study.
CONCLUSIONS: Skipping breakfast can increase the risk of depression. It suggests that we should pay attention to having a regular and standardized breakfast to reduce the risk of depression. High heterogeneity may stem from differences in dietary culture and assessment methods. In the future, more research is needed to explore the mechanism and increase studies in different regions.
SYSTEMATIC REVIEW REGISTRATION: https://www.crd.york.ac.uk/prospero/, identifier PROSPERO CRD42024583486.
PMID:40838254 | PMC:PMC12362717 | DOI:10.3389/fpsyt.2025.1548282
Front Psychiatry. 2025 Aug 5;16:1590850. doi: 10.3389/fpsyt.2025.1590850. eCollection 2025.
ABSTRACT
OBJECTIVES: This study aimed to evaluate the utility of P300 event-related potentials (ERPs) as neurophysiological biomarkers for diagnosing attention deficit hyperactivity disorder (ADHD) and to establish preliminary diagnostic thresholds for their use.
METHODS: A total of 106 children diagnosed with ADHD and 66 healthy controls were enrolled. Using a visual Oddball paradigm, P300 parameters were recorded at Fz, Cz, and Pz zones. Key metrics analyzed included P300 amplitude and latency as well as reaction time and correct responses. Statistical tests and logistic regression analysis identified significant group differences, while receiver operating characteristic (ROC) analysis determined the diagnostic performance of these parameters.
RESULTS: Children with ADHD exhibited significantly lower P300 amplitudes and longer latencies across all electrode sites compared to controls. Logistic regression identified Cz amplitude (p = 0.001), Pz amplitude (p = 0.011), maximum reaction time (p = 0.037), and correct response count (p < 0.001) as significant predictors of ADHD. ROC analysis showed that Cz amplitude, Pz amplitude, maximum reaction time, and correct responses achieved AUCs of 0.81, 0.75, 0.72, and 0.86, respectively, with sensitivities ranging from 66% to 80% and specificities from 61% to 95%. These results underscore the diagnostic potential of both electrophysiological and behavioral markers in ADHD assessment.
CONCLUSIONS: Cz and Pz amplitude, maximum reaction time, and correct responses each demonstrated strong diagnostic utility for distinguishing ADHD from typically developing children. The use of these neurophysiological and behavioral indicators as objective complements to traditional clinical assessments.
PMID:40838253 | PMC:PMC12362261 | DOI:10.3389/fpsyt.2025.1590850
North Clin Istanb. 2025 Feb 4;12(1):111-120. doi: 10.14744/nci.2024.61224. eCollection 2025.
ABSTRACT
OBJECTIVE: Medical students try to cope with challenging emotional experiences caused by stress factors specific to medical education during their education. In this process, students’ cognitive emotion regulation (CER) strategies and psychological resilience (PR) act as protective mechanisms to alleviate the impact of challenging emotions. Therefore, it is important for medical students to use adaptive emotion regulation strategies and demonstrate psychological resilience in the face of challenging emotional experiences. This study aimed to reveal the effects of CER strategies and PR on the emotional well-being (EWB) of medical students and the mediating effect of PR in the relationship between CER strategies and EWB.
METHODS: In this study, Structural Equation Modeling (SEM) was used to determine the mediating effect of PR in the relationship between CER strategies and EWB. The sample of the study consisted of 210 students who were randomly selected from the 1st and 4th year medical students and volunteered to participate in the study. Cognitive Emotion Regulation Scale, Psychological Resilience Scale and Emotional Well-Being Scale, which are the data collection tools of the study, were administered to the participants face-to-face by the researchers. Descriptive statistics and correlations were analyzed with SPSS 26. The SEM was analyzed with Jamovi 2.3.19 SEM module and R 4.1.1 Iavaan package.
RESULTS: 54.8% (n=115) of the participants were 1st-grade and 45.2% (n=95) were 4th-grade students; 54.8% were male and 45.2% were female. The results of SEM analysis showed that the relationship between adaptive CER strategies in the two sub-scales (refocusing on plan; β=0.088, p=0.011 and positive reappraisal; β=0.175, p<0.001) and EWB was found to be mediated by the commitment sub-scale of PR.
CONCLUSION: This study showed that the relationship between positive reappraisal and refocusing on a plan, which are adaptive CER strategies, and EWB was mediated by PR-commitment. These results indicate that CER and PR stand out as concepts that support students’ EWB in medical education.
PMID:40838246 | PMC:PMC12364463 | DOI:10.14744/nci.2024.61224
North Clin Istanb. 2025 Feb 3;12(1):12-20. doi: 10.14744/nci.2023.66891. eCollection 2025.
ABSTRACT
OBJECTIVE: The purpose of this study is to analyze the situation of Methicillin-Resistant Staphylococcus aureus (MRSA) in TRNC by examining the prevalence of Community-acquired Methicillin-Resistant Staphylococcus aureus (CA-MRSA)/Hospital-acquired Methicillin-Resistant Staphylococcus aureus (HA-MRSA) cases, the acceleration of CA-MRSA/HA-MRSA patients from past to present, the impact of pandemic, gender and age on MRSA cases.
METHODS: In order to analyze the trend of MRSA cases and the effects of selected parameters on MRSA cases, statistical tests are employed to the obtained data including ANOVA test, regression analysis tests and Post-hoc Tukey test.
RESULTS: Incidence rate of MRSA carriage in the community has increased over the years to 45.6%. p-value of the relationship between community-acquired MRSA cases and hospital-acquired MRSA cases is less than 0.05. The results also revealed that the p-value of both the relationship between COVID-19 and MRSA cases and the relationship between 50+ age and MRSA cases are significant. On the other hand, p-value of the relationship between gender and MRSA cases is found to be greater than 0.05.
CONCLUSION: It is concluded that MRSA carriage in the community has increased over the years and CA-MRSA and HA-MRSA cases are related since p<0.05. Moreover, it’s revealed that there is an effect of COVID-19 pandemic and 50+ age (66% of the cases) on MRSA cases because of p<0.05 while the gender is not an effect for MRSA cases in the country, since p-value for gender comparison is greater than 0.05.
PMID:40838240 | PMC:PMC12364480 | DOI:10.14744/nci.2023.66891
North Clin Istanb. 2025 Feb 4;12(1):55-61. doi: 10.14744/nci.2023.84770. eCollection 2025.
ABSTRACT
OBJECTIVE: To investigate the effects of methylenetetrahydrofolate reductase (MTHFR) gene C677T/A1298C polymorphisms on serum homocysteine levels and hypertension.
METHODS: Venous blood samples were collected in EDTA tubes from patients and controls (80 hypertensive patients and 67 healthy controls) and genomic DNA was isolated. The polymorphisms of MTHFR C677T and A1298C were identified using the polymerase chain reaction (PCR) and restriction fragment length polymorphisms (RFLP) technique. The enzyme-linked immunosorbent assay (ELISA) method was used to determine serum homocysteine levels. ANOVA, Student’s t-test, chi-square test and logistic regression analysis tests used in the evaluation of statistical analysis between patient and control groups were performed with SPSS 21.0 program.
RESULTS: A statistically significant difference was observed between the patient group, which were hypertension-diagnosed patients, and control group for C677T polymorphism (p<0.001), but not for the A1298C polymorphism (p=0.058). When serum homocysteine levels were compared between the patient and control groups, no significant difference was observed (p=0.065). A significant difference was observed between C677T allele frequency (TT + CT versus CC) and homocysteine levels in both groups (p=0.027), whereas no significant difference was observed between A1298C allele frequency (CC + AC versus AA) and homocysteine levels (p=0.996).
CONCLUSION: The MTHFR C677T polymorphism is more common in hypertensive patients. T allele frequencies (CT and TT genotypes) and TT genotypes might increase the risk of hypertension and homocysteine levels. Although the A1298C C allele frequency (AC and CC genotypes) might increase the risk of hypertension, CC genotype distributions and homocysteine levels show no statistical significance on hypertension. C677T polymorphism is associated with hypertension thus it may be used as a potential biomarker.
PMID:40838236 | PMC:PMC12364473 | DOI:10.14744/nci.2023.84770
North Clin Istanb. 2025 Feb 3;12(1):1-11. doi: 10.14744/nci.2023.40799. eCollection 2025.
ABSTRACT
OBJECTIVE: In our study, our aim was to compare the clinical outcomes of utilizing a 6-stranded hamstring autograft (HAG) lacking tibial attachment site separation in Anterior Cruciate Ligament Reconstruction (ACLR), an approach previously unreported in literature, with alternative methodologies.
METHODS: A total of 85 patients admitted to our Orthopedics and Traumatology clinic between April 2019 and July 2022 with Anterior Cruciate Ligament (ACL) rupture, who underwent surgical treatment, were retrospectively analyzed. ACLR was initiated using HAG in all patients. The surgical procedure was determined based on the length of the HAG used during ACLR. In all cases, femoral fixation was performed with an adjustable loop endobutton. 3 methods were applied to all patients. These are: repair with a 6-strand hamstring tendon graft without severing the tibial insertion (new method), repair with 4-strand hamstring tendon graft without severing the tibial insertion and repair with 4-strand hamstring tendon graft without protecting the tibial insertion. Preoperative and postoperative International Knee Documentation Committee (IKDC) subjective evaluation score, Lysholm score and Tegner activity score were used in the evaluation of the patients. Comparisons between groups were made according to these scores.
RESULTS: 78 patients were included in the study. There were 31 patients in Group 1, 23 in Group 2 and 24 in Group 3. The mean age of the patients was 29 (19-40) in Group 1, 32 (16-49) in Group 2 and 31 (18-54) in Group 3. In the comparison of the groups, there was a significant increase in tendon thickness in Group 1 (p<0.001) and a significant decrease in the rate of re-rupture as a complication (p<0.05). There was no statistically significant difference between the groups in terms of age, side of surgery, follow-up period, and length of hospital stay. There was statistical significance between Group 1 and Group 2 in terms of tendon diameter (p<0.05) and re-rupture (p<0.05). In the comparison of Group 2 and Group 3, there was statistical significance between Group 2 and Group 3 in terms of tendon thickness and length of hospital stay (p<0.05), while no significant difference was found in terms of re-rupture (p>0.05).
CONCLUSION: ACLR with 6-strand tendon graft with preservation of the HAG insertion is not a method described in the literature. As a result of our study, it was concluded that the functional results of this newly described method are as good as other methods and have lower re-rupture rates.
PMID:40838235 | PMC:PMC12364475 | DOI:10.14744/nci.2023.40799