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Nevin Manimala Statistics

Performance assessment of the MOF adsorbent MIL-101 for removal of gaseous benzene and toluene: kinetic column modeling and simulation studies of fixed-bed adsorption

Environ Sci Pollut Res Int. 2023 Jun 12. doi: 10.1007/s11356-023-28019-5. Online ahead of print.

ABSTRACT

The adsorbent MIL-101, a metal-organic framework material, was synthesized, characterized, and tested for removal of relatively low concentrations of benzene and toluene adsorbates (200 ppm) from a gas phase in a continuous flow system. Breakthrough studies were modeled based on Thomas, Yoon-Nelson, Yan, Clark, Bohart-Adams, bed-depth service time, modified dose response, Wolborska, and Gompertz in the continuous fixed-bed operation. Through statistical analysis, it was determined which type of regression is most suitable for the studied models, linear or nonlinear. By comparing the values of error functions, it was possible to infer that the Thomas model is the best match for the experimental breakthrough curves for benzene (with maximum solid-phase concentration qT=126,750 mg/g) and the Gompertz model for toluene (parameter β=0.01 min-1). Overall, when compared to the model parameters of the linear regression, those obtained through nonlinear regression show a stronger correlation with the results found experimentally. Thus, this type of regression is more suitable for the adsorption model analysis. The liquid film and intraparticle diffusion analysis was described, and it was suggested that both types of diffusion contribute to the adsorption mechanism of benzene and toluene on MIL-101. As for the isotherms, the adsorption process was better fitted by the Freundlich isotherm. The reusability of MIL-101 after six cycles was 76.5% for benzene and 62.4% for toluene, indicating that MIL-101 was a better adsorbent for the removal of benzene in comparison with toluene.

PMID:37306882 | DOI:10.1007/s11356-023-28019-5

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Nevin Manimala Statistics

Estimation of root canal conicity of deciduous canines evaluated by nano-CT

Eur Arch Paediatr Dent. 2023 Jun 12. doi: 10.1007/s40368-023-00809-y. Online ahead of print.

ABSTRACT

PURPOSE: To estimate the taper of root canals of deciduous maxillary and mandibular canines by nano computed tomography (nano-CT).

METHODS: This in vitro study involved CT scan analysis of nine maxillary and five mandibular primary canines. The images of each tooth were reconstructed using OnDemand3D software. Thereon, diameter and taper analyses were performed on the free FreeCAD 0.18 software for the three-dimensional (3D) computer-aided design model. Statistical analysis was conducted using Stata v14.0 software, adopting a significance level of 5%.

RESULTS: 3D image reconstruction was performed, considering the diameters obtained along the entire length of the tooth root, and the conical model was built with a height of 10 mm. The diameters of the maxillary canine at points D0 (0 mm), D5 (5 mm), D7 (7 mm), and D10 (10 mm) were 1.62, 1.07, 0.78, and 0.49 mm, respectively, with a significant difference between the four points (p = 0.0001). Regarding maxillary canine root taper values in the cervical, middle, and apical regions, the values were 12%, 14%, and 10%, respectively. For mandibular canines, the mean diameter values obtained at points D0, D5, D7, and D10 were 1.51, 0.83, 0.64, and 0.45 mm, respectively, with significant differences among the four points (p = 0.005). The inferior canine root tapers in the cervical, middle, and apical regions were 14%, 10%, and 6%, respectively.

CONCLUSION: The detailed knowledge of the root morphology of maxillary and mandibular deciduous canines, as it has been shown in vitro using nano-CT, is critical to achieve accurate and efficient endodontic treatments.

PMID:37306868 | DOI:10.1007/s40368-023-00809-y

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Nevin Manimala Statistics

Psychometric Properties of the Haitian Creole Brief Religious Coping Scale (RCOPE) with a Sample of Adult Haitians Impacted by the 2010 Earthquake

J Relig Health. 2023 Jun 12. doi: 10.1007/s10943-023-01853-0. Online ahead of print.

ABSTRACT

The current study investigated the psychometric properties of the Haitian Creole version of the Brief Religious Coping Scale (Brief RCOPE). A total of 256 adult survivors of the 2010 earthquake in Haiti completed the Brief RCOPE and measures of posttraumatic stress disorder symptoms, resilience, general coping, and posttraumatic growth. The results showed the Brief RCOPE to have excellent internal consistency reliability α = .94 and α = .85 for the positive religious coping and negative religious coping, respectively. Confirmatory factor analysis showed construct validity for the Brief RCOPE subscales. The results also showed evidence of convergent validity of the Brief RCOPE in relation to measures of positive spiritual change and religion. Independent t-tests revealed statistically significant gender differences in scores on the positive religious coping subscales as women scored higher than men. These findings suggest that the psychometric properties of the Haitian Creole version of the Brief RCOPE are adequate for the assessment of religious coping with Haitian adults exposed to a natural disaster.

PMID:37306861 | DOI:10.1007/s10943-023-01853-0

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Nevin Manimala Statistics

Death anxiety predicts fear of Cancer recurrence and progression in ovarian Cancer patients over and above other cognitive factors

J Behav Med. 2023 Jun 12. doi: 10.1007/s10865-023-00422-w. Online ahead of print.

ABSTRACT

Death anxiety is understudied in people with cancer, especially in relation to fear of cancer recurrence (FCR) and fear of progression (FOP). The present study aimed to identify if death anxiety can predict FCR and FOP over and above other known theoretical predictors. One hundred and seventy-six participants with ovarian cancer were recruited for an online survey. We included theoretical variables, such as metacognitions, intrusive thoughts about cancer, perceived risk of recurrence or progression, and threat appraisal, in regression analyses to predict FCR or FOP. We investigated whether death anxiety added to the variance over and above these variables. Correlational analyses demonstrated that death anxiety is more strongly associated with FOP than FCR. The hierarchical regression including the theoretical variables described above predicted 62-66% of variance in FCR and FOP. In both models, death anxiety predicted a small but statistically significant unique variance in FCR and FOP. These findings draw attention to the importance of death anxiety in understanding FCR and FOP in people with a diagnosis of ovarian cancer. They also suggest that elements of exposure and existentialist therapies may be relevant in treating FCR and FOP.

PMID:37306857 | DOI:10.1007/s10865-023-00422-w

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Nevin Manimala Statistics

Impact of economic variables on CO2 emissions in belt and road and OECD countries

Environ Monit Assess. 2023 Jun 12;195(7):835. doi: 10.1007/s10661-023-11440-1.

ABSTRACT

The rebirth of the Belt and Road Initiative (BRI) programme have necessitated the study as it has a vast potential to promote economic growth, yet, marred with numerous energy use and ecological concerns. The article is the first to comparatively examine the impact of economic variables on consumption-based CO2 emissions in the BRI and the Organisation for Economic Co-operation and Development (OECD) countries by testing the Environmental Kuznets Curve (EKC) and the Pollution Haven Hypothesis (PHH). The Common Correlated Effects Mean Group (CCEMG) estimates the results. Income (GDP) and GDP2 positively and negatively impact CO2 emissions in the three panels, validating the EKC. Foreign direct investment (FDI) significantly affects CO2 emissions for the global and BRI panels, supporting the PHH. However, the PHH is refuted for the OECD panel as the impact of FDI on CO2 emissions is negative and statistically significant. GDP and GDP2 decline by 0.029% and 0.0446%, respectively, for BRI countries, compared to OECD countries. It is recommended that BRI countries enact new and stringent environmental laws and use more tidal energy, solar energy, wind power, bioenergy, and hydropower instead of fossil fuels, for the sustainable attainment of higher economic growth, devoid of pollution.

PMID:37306854 | DOI:10.1007/s10661-023-11440-1

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Nevin Manimala Statistics

Why do Integrated Maternal HIV and Infant Healthcare Services work? A Secondary Analysis of a Randomised Controlled Trial in South Africa

AIDS Behav. 2023 Jun 12. doi: 10.1007/s10461-023-04097-x. Online ahead of print.

ABSTRACT

In a randomised trial, we found that integrated maternal HIV and infant health services through the end of breastfeeding were significantly associated with the primary outcome of engagement in HIV care and viral suppression at 12 months postpartum, compared to the standard of care. Here, we quantitatively explore potential psychosocial modifiers and mediators of this association. Our findings suggest that the intervention was significantly more effective among women experiencing an unintended pregnancy but did not improve outcomes among women reporting risky alcohol use. Although not statistically significant, our results suggest that the intervention may also be more effective among women experiencing higher levels of poverty and HIV-related stigma. We observed no definitive mediator of the intervention effect, but women allocated to integrated services reported better relationships with their healthcare providers through 12 months postpartum. These findings point to high-risk groups that may benefit the most from integrated care, as well as groups for whom these benefits are hampered and that warrant further attention in intervention development and evaluation.

PMID:37306847 | DOI:10.1007/s10461-023-04097-x

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Nevin Manimala Statistics

Descriptive Epidemiology of Fatal Law Enforcement Interactions with Teenagers, 2010-2020

J Community Health. 2023 Jun 12. doi: 10.1007/s10900-023-01243-3. Online ahead of print.

ABSTRACT

There is a dearth of population studies regarding law enforcement officers (LEOs) use of fatal force against teenagers. The purpose of this cross-sectional study was to characterize the teens most likely to be killed, the methods used to fatally injure teenagers, the geographic distribution of the killings, and the years of potential life lost before the age of 80 years (YPLL80) due to LEO interactions. Data from the Web-based Injury Statistics Query and Reporting System (WISQARS) from the Center for Disease Control and Prevention (CDC) were analyzed for the years 2010-2020. LEOs killed 330 teenagers; most were males (94.2%) and 6 of 7 teens (84.5%) were shot. The teens killed were disproportionately older teens ages 18-19 years (64.2%) and non-Hispanic Blacks (45.8%) who were usually killed in metropolitan areas (90.0%). The rate of teenage killings by LEOs significantly increased (267%) over the time frame studied. A total of 20,575 YPLL80 were lost and they significantly increased over time (263%). Mitigation of teenagers killed by LEOs will require transforming policing through policy changes (e.g. hiring and training) over an extended period of time. Also, the public needs education, (e.g. funding, interactions) regarding policing.

PMID:37306842 | DOI:10.1007/s10900-023-01243-3

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Nevin Manimala Statistics

Exercise alters cortico-basal ganglia network metabolic connectivity: a mesoscopic level analysis informed by anatomic parcellation defined in the mouse brain connectome

Brain Struct Funct. 2023 Jun 12. doi: 10.1007/s00429-023-02659-2. Online ahead of print.

ABSTRACT

The basal ganglia are important modulators of the cognitive and motor benefits of exercise. However, the neural networks underlying these benefits remain poorly understood. Our study systematically analyzed exercise-associated changes in metabolic connectivity in the cortico-basal ganglia-thalamic network during the performance of a new motor task, with regions-of-interest defined based on mesoscopic domains recently defined in the mouse brain structural connectome. Mice were trained on a motorized treadmill for six weeks or remained sedentary (control), thereafter undergoing [14C]-2-deoxyglucose metabolic brain mapping during wheel walking. Regional cerebral glucose uptake (rCGU) was analyzed in 3-dimensional brains reconstructed from autoradiographic brain sections using statistical parametric mapping. Metabolic connectivity was assessed by calculating inter-regional correlation of rCGU cross-sectionally across subjects within a group. Compared to controls, exercised animals showed broad decreases in rCGU in motor areas, but increases in limbic areas, as well as the visual and association cortices. In addition, exercised animals showed (i) increased positive metabolic connectivity within and between the motor cortex and caudoputamen (CP), (ii) newly emerged negative connectivity of the substantia nigra pars reticulata with the globus pallidus externus, and CP, and (iii) reduced connectivity of the prefrontal cortex (PFC). Increased metabolic connectivity in the motor circuit in the absence of increases in rCGU strongly suggests greater network efficiency, which is also supported by the reduced involvement of PFC-mediated cognitive control during the performance of a new motor task. Our study delineates exercise-associated changes in functional circuitry at the subregional level and provides a framework for understanding the effects of exercise on functions of the cortico-basal ganglia-thalamic network.

PMID:37306809 | DOI:10.1007/s00429-023-02659-2

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Nevin Manimala Statistics

Effects of continuous use of Tadalafil on male sexual function after posterior urethroplasty: A clinical trial

Urologia. 2023 Jun 12:3915603231179533. doi: 10.1177/03915603231179533. Online ahead of print.

ABSTRACT

INTRODUCTION: Posterior urethral injuries in men commonly occur following pelvic and perineal trauma. Erectile dysfunction (ED), whether brought on by the severity of the initial trauma or the surgery itself, is one of the complications in these patients.

MATERIALS AND METHODS: In this study, we divided candidates of posterior urethroplasty due to traumatic urethral injury into intervention and placebo groups; the former received continuous treatment with tadalafil (10 mg daily), and the latter received a placebo. Other services were provided equally to both groups. Before and after the intervention, both groups completed the International Index of Erectile Function version 5 (IIEF-5) questionnaire, and the findings were analyzed.

RESULTS: Forty patients were studied in groups of 20 with a mean age of 43.87 ± 15.70 years. The patient’s most common cause of urethral injury was a pelvic fracture. Before the intervention, the mean scores of IIEF for patients in the intervention group and placebo group were 14.85 ± 7.39 and 14.77 ± 6.48, respectively with no statistical significance (p = 0.962) and patients of the groups were similar in terms of the severity of ED. The mean IIEF score in the intervention group was 20.12 ± 4.94 and in the placebo group, it was 18.05 ± 4.88 at the three-month follow-up, with no statistically significant difference (p = 0.063). In both the intervention and placebo groups, the IIEF score was significantly increased by 5.27 ± 4.04 (p < 0.001) and 3.27 ± 2.97 (p < 0.001), respectively. The rate of IIEF increase in the intervention group was higher than in the placebo group during the follow-up at 3-month follow-up with statistical significance. (p = 0.022).

CONCLUSION: The findings of this study suggest that tadalafil, in a 3-month treatment course, may improve erectile function in individuals with mild-to-moderate ED, significantly more than placebo. However, more studies, specifically with longer duration of follow-up and larger populations, are necessary for generalizing the current findings.

PMID:37306088 | DOI:10.1177/03915603231179533

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Nevin Manimala Statistics

Timelines of Adverse Event Journeys of LVAD Patients

Artif Organs. 2023 Jun 12. doi: 10.1111/aor.14596. Online ahead of print.

ABSTRACT

OBJECTIVE: The INTERMACS Events data set contains an expansive collection of temporal evidence of the course of adverse events (AEs) of > 15, 000 patients that have received an left ventricular assist device (LVAD). The chronology of AEs may contain insightful information of the “AE journeys” of LVAD patients. The purpose of this study is to investigate the timelines of AEs within the INTERMACS database.

METHODS: Descriptive statistics were applied to 86,912 recorded AEs of 15,820 patients with a continuous flow-LVAD between 2008 to 2016, extracted from INTERMACS registry. The characteristics of the timelines of AE journeys were investigated by posing six descriptive research questions.

RESULTS: The analysis revealed several time-related characteristics and patterns of the AE journey after LVAD including the most common time of occurrences of AEs after surgery, duration of AEs journeys, the time of first and last AEs, and the time gaps between AEs.

CONCLUSION: The INTERMACS Event data set is a valuable resource for research about the timeline of AE journeys of patients who received an LVAD. It is necessary for future studies to first explore and consider the time-related characteristics of the data set such as diversity and sparsity to effectively choose an appropriate scope of time and time granularity and to acknowledge potential challenges.

PMID:37306077 | DOI:10.1111/aor.14596