Nevin Manimala

Ind Psychiatry J. 2023 Jan-Jun;32(1):142-149. doi: 10.4103/ipj.ipj_115_22. Epub 2022 Dec 23.

ABSTRACT

BACKGROUND: Although the potential for alternate conceptions of gender roles and sexual orientations are diverse, it is by-and-large not well tolerated. This study explores the self-reported gender-roles and sexual orientations of Indian undergraduate medical students.

AIM: To study self-reported gender role and sexual orientation of undergraduate medical students in India.

METHOD: One hundred twenty volunteers were included in the study consisting of 60 males and 60 females. A questionnaire comprising of a sociodemographic proforma, Bem Sex-Role Inventory (BSRI), and Epstein Sexual Orientation Inventory (ESOI) were given to each participant. The scales were scored, tabulated, and statistically analyzed.

RESULTS: The BSRI revealed that femininity was predominant in both female and male participants, at 68.33% and 55%, respectively. The ESOI revealed that females had significantly higher opposite-sex attraction than males. Though males had higher same-sex attraction than females, the difference was not statistically significant. Females also had a significantly higher sexual orientation range and a mean sexual orientation. Sexual drive was significantly higher in males. Significantly more females supported homosexuality and bisexuality as compared to males.

CONCLUSION: This study helps establish that gender roles can be non-conforming. It helps ascertain that while heterosexual orientation predominates, alternate sexual orientations also exist. It paves the way for future studies and explorations to alleviate public misconceptions.

PMID:37274584 | PMC:PMC10236688 | DOI:10.4103/ipj.ipj_115_22

Glob Public Health. 2023 Jan;18(1):2217445. doi: 10.1080/17441692.2023.2217445.

ABSTRACT

Behind the statistics forecasting millions of deaths associated with antimicrobial resistance (AMR) is an even greater burden of morbidity leaving many people with long-term chronic illnesses and disability. Despite growing recognition of the importance of inter-sectoral and inter-disciplinary knowledge in forming responses to address this global health threat, there remains a paucity of social science research to understand the social burdens of AMR. In this qualitative study we explore the experiences of people living with chronic AMR infections, their interactions with health providers and therapeutic quests for care, and the effects upon their lives and that of their families and caregivers. Our analysis reveals that the resistant infections impacted not only the physical health but also the mental health of the sufferers and their caregivers, causing major disruptions to their social and work lives. Most undertook arduous treatment regimes – of powerful antibiotics with debilitating side effects, combined a range of other complementary and alternate therapies, including travel to seek treatment overseas. Further, we question the notion of ‘AMR survivorship’ currently being promoted as part of a public education campaign by the World Health Organisation and whether people with the diverse AMR experience really self-identify as ‘survivors’ of a biosocial group.

PMID:37272390 | DOI:10.1080/17441692.2023.2217445

Twin Res Hum Genet. 2023 Jun 5:1-10. doi: 10.1017/thg.2023.19. Online ahead of print.

ABSTRACT

Joseph has written what purports to be a refutation of studies of Twins Reared-Apart (TRAs) with a singular focus on the Minnesota Study of Twins Reared-Apart (MISTRA). I show, in detail, that (a) his criticisms of previous TRA studies depend on sources that were discredited prior to MISTRA, as they all failed the test of replicability, (b) the list of biases he uses to invalidate MISTRA do not support his arguments, (c) the accusations of questionable research practices are unsubstantiated, (d) his claim that MISTRA should be evaluated in the context of psychology’s replication crisis is refuted. The TRA studies are constructive replications. Like many other scholars, past and present, he has been misled by the variation introduced by small samples (sampling error) and the distortion created by walking in the garden of forking paths. His endeavor is a concatenation of elision and erroneous statistical/scientific reasoning.

PMID:37272376 | DOI:10.1017/thg.2023.19

Int J Comput Dent. 2023 Jun 5;0(0):0. doi: 10.3290/j.ijcd.b4140897. Online ahead of print.

ABSTRACT

AIM: The aim of this study was to evaluate the segmentation accuracy of dentition testing four free-source semi-automatic software.

MATERIALS AND METHODS: A total of 20 cone-beam computed tomography (CBCT) were selected to perform semi-automatic segmentation of maxillary and mandibular dentition. The software tested were Invesalius, ITK-Snap, 3D Slicer and Seg3D. Each tooth model was also manually segmented (Mimics software) and set as the gold standard (GS) reference of the investigation. A specific 3D imaging technology was used to perform the superimposition between the teeth models obtained with semi-automatic software and the GS model, and to perform the surface-to-surface matching analysis. The accuracy of semi-automatic segmentation was evaluated calculating the volumetric mean differences (mean bias and limits of agreement) and the percentage of matching of the tooth models compared to the manual segmentation (GS). Qualitative assessments were performed using color-coded maps. All data were statistically analysed to perform software comparisons.

RESULT: Statistically significant differences were found in the volumetric and matching percentage data (p < 0,05). Invesalius was the most accurate software for 3D rendering of the dentition with a volumetric bias (Mimics) ranging from 4,59 mm3 to 85,79 mm3; instead, ITK-SNAP showed the higher volumetric bias, ranging from 30,22 mm3 to 319,83 mm3. The dis-matched area was mainly located at the radicular region of the teeth. Volumetric data showed excellent inter-software reliability with coefficient values ranging from 0,951 to 0,997.

CONCLUSIO: Different semi-automatic software algorithms could generate different patterns of inaccuracy error in the segmentation of teeth.

PMID:37272346 | DOI:10.3290/j.ijcd.b4140897

Trauma Violence Abuse. 2023 Jun 5:15248380231176056. doi: 10.1177/15248380231176056. Online ahead of print.

ABSTRACT

Given the pervasiveness of violent extremism all over the globe, understanding its psychological underpinnings is key in the fight against it. According to the Significance Quest Theory and its 3N model, violent extremism (i.e., violent and deviant behavior) is a function of three elements: need, narrative, and network. In the present meta-analysis, to put into test the theory and its model, we aimed to establish the strength of the association between these three elements, as well as the quest for significance itself, and violent extremism; and investigate if these associations are influenced by methodological decisions (i.e., sampling and measurements/manipulations). A literature search was performed through electronic platforms, a call for unpublished or in-press data, and backward snowballing. Seventeen reports, comprising 42 studies, met full inclusion criteria: quantitative studies based on primary data assessing for the association of at least one of the 3Ns, or quest for significance, and violent extremism, and providing sufficient data for effect size extraction. Findings are reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA) guidelines. Random-effect meta-analyses rendered statistically significant pooled effect sizes in all the investigated associations. The association is strong for quest for significance, moderate for narrative and network, and low for need for significance. Subgroup analyses demonstrate that the detection of these associations is influenced by methodological decisions concerning the measurements and manipulations, but not by those concerning the sampling. We discuss these findings and suggest future research directions aiming to improve the predictive power of the theory and its model.

PMID:37272343 | DOI:10.1177/15248380231176056

Int J Speech Lang Pathol. 2023 Jun 5:1-13. doi: 10.1080/17549507.2023.2181220. Online ahead of print.

ABSTRACT

PURPOSE: This study aims to describe the experiences and needs of Canadian speech-language pathologists (SLPs) who conducted communication assessments via telepractice across the lifespan during the first year (2020) of the COVID-19 pandemic.

METHOD: The present study consisted of an online survey that aimed to capture both quantitative aspects of telepractice-based communication assessment and the qualitative experience of shifting to telepractice. One hundred sixty-eight practicing SLPs across Canada participated in the survey, between September 2020 and January 2021. Quantitative results were analysed using descriptive statistics while open-ended responses were analysed using thematic analysis.

RESULT: SLPs identified challenges and opportunities relating to client and family engagement, access to and knowledge of technology, and the reliability of assessment tools. SLPs also identified a future need for online assessment materials and training, such as materials adapted for different communication needs (e.g. augmentative and alternative communication).

CONCLUSION: The present study contributes to a growing understanding worldwide of potential benefits and challenges related to telepractice, fuelled by the necessary shift in practices in our field during the COVID-19 pandemic. The results provide direction for continuing to build a valid and inclusive approach to telepractice in the future.

PMID:37272330 | DOI:10.1080/17549507.2023.2181220

J Biol Dyn. 2023 Dec;17(1):2220349. doi: 10.1080/17513758.2023.2220349.

ABSTRACT

In this work, we set up a new discrete predator-prey competitive model with time-varying delays and feedback controls. By virtue of the difference inequality knowledge, a sufficient condition which guarantees the permanence of the established discrete predator-prey competitive model with time-varying delays and feedback controls is derived. Under some appropriate parameter conditions, we have proved that the periodic solution of the system without delay exists and globally attractive. To verify the correctness of the derived theoretical fruits, we give two examples and execute computer simulations. Our obtained results are novel and complement previous known results.

PMID:37272309 | DOI:10.1080/17513758.2023.2220349

Diagn Interv Radiol. 2023 Jun 5. doi: 10.4274/dir.2023.232129. Online ahead of print.

ABSTRACT

PURPOSE: To evaluate the efficacy of interventional radiological (IR) procedures in iatrogenic urinary tract injury and investigate the factors affecting the outcome.

METHODS: Fifty-eight patients (21 male) with a mean age of 50.3 ± 15.8 years referred for iatrogenic urinary tract injury were enrolled in this study. Technical success was defined as (i) successful placement of a nephrostomy catheter within the renal pelvis and/or (ii) successful antegrade ureteral stent placement (double J stent) between the renal pelvis and bladder lumen. Complete resolution was defined as maintained ureteral patency without an external drain and ureteral stent. The factors that may affect complete resolution [ureteral avulsion, ureterovaginal fistula (UVF), history of malignancy/radiotherapy, and time to IR management] were also investigated. The receiver operating characteristic analysis was performed to estimate the cut-off time point for the IR management timing affecting complete resolution.

RESULTS: The technical success rate for nephrostomy and ureteral stent placement was 100% (n = 58/58) and 78% (n = 28/36), respectively. In 14 patients, non-dilated pelvicalyceal systems were evident. In 18 patients, no further intervention after percutaneous nephrostomy was performed due to (i) poor performance status (n = 6) and (ii) reconstruction surgery upon clinicians’ and/or patients’ request (n = 12). Reconstruction surgery was required in 11 of the remaining 40 patients due to failure of percutaneous treatment (n = 11/40, 27.5%). In six of the patients, ureteral stents could not be removed due to the development of benign ureteral strictures (n = 6/40, 15%). Our complete resolution rate was 57.5% (n = 23/40). Age, gender, type of surgery (endoscopic or open), side and location of the injury did not statistically affect the complete resolution rate. The presence of ureteral avulsion, history of malignancy and radiotherapy individually or in combination significantly affected the complete resolution rate negatively. The presence of UVF also had a negative effect on the complete resolution rate; however, it did not reach statistical significance. Delayed intervention was also a significant factor related to lower complete resolution. The optimal cut-off point of the time interval for favorable clinical outcome was found to be 0-19^th day following the surgery.

CONCLUSION: IR procedures are safe and effective in the management of iatrogenic urinary tract injuries. Antegrade ureteral stenting should be performed as soon as possible to establish ureteral integrity without the development of stricture.

PMID:37272307 | DOI:10.4274/dir.2023.232129

Nucl Med Commun. 2023 Jun 5. doi: 10.1097/MNM.0000000000001717. Online ahead of print.

ABSTRACT

BACKGROUND: Although it causes low-dose radiation exposure, dimercaptosuccinic acid (DMSA) renal cortical scintigraphy is the gold standard examination method in the noninvasive diagnosis of renal scar tissue (RST). Shear wave elastography (SWE) has recently come to the fore as a technique for measuring kidney stiffness in the examination of RST. The present study aims to compare DMSA and SWE tests to evaluate whether SWE can be used instead of DMSA as a test that does not cause radiation exposure in pediatric patients.

METHODS: In this prospective study, sonographic elastography was performed on pediatric patients with DMSA images. In the SWE examination, measurements were made from each kidney’s upper, middle and lower parts. DMSA and elastography data were compared for the diagnosis of RST.

RESULTS: A total of 64 patients were included in the present study. There were 68.8% female (n = 44) and 31.2% (n = 20) male patients. There were 45 pediatric patients [Female 30 (66.7%), male 15 (33.3%)] in group 1 (pathological group) and 19 pediatric patients [Female 14 (73.7%), male 5 (26.3%)] in the control group. When DMSA data and SWE values were compared, it was found that elastography did not show a statistically significant performance in predicting renal scarring.

CONCLUSION: In the existing literature, various studies reported different values for the diagnosis of renal stiffness using SWE. Similar to some previous studies, the present study observed no significant correlations between DMSA and SWE. Thus, DMSA preserves its major role and effectiveness as an important predictor of RST in pediatric patients.

PMID:37272283 | DOI:10.1097/MNM.0000000000001717

Nucl Med Commun. 2023 Jun 5. doi: 10.1097/MNM.0000000000001712. Online ahead of print.

ABSTRACT

INTRODUCTION: A DnCNN for image denoising trained with natural images is available in MATLAB. For Tc-99m DMSA images, any loss of clinical details during the denoising process will have serious consequences since denoised image is to be used for diagnosis. The objective of the study was to find whether this pre-trained DnCNN can be used for denoising Tc-99m DMSA images and compare its performance with block matching 3D (BM3D) filter.

MATERIALS AND METHODS: Two hundred forty-two Tc-99m DMSA images were denoised using BM3D filter (at sigma = 5, 10, 15, 20, and 25) and DnCNN. The original and denoised images were reviewed by two nuclear medicine physicians and also assessed objectively using the image quality metrics: SSIM, FSIM, MultiSSIM, PIQE, Blur, GCF, and Brightness. Wilcoxon signed-rank test was applied to find the statistically significant difference between the value of image quality metrics of the denoised images and the corresponding original images.

RESULTS: Nuclear medicine physicians observed no loss of clinical information in DnCNN denoised image and superior image quality compared to its original and BM3D denoised images. Edges/boundaries of the scar were found to be well preserved, and doubtful scar became obvious in the denoised image. Objective assessment also showed that the quality of DnCNN denoised images was significantly better than that of original images at P-value <0.0001.

CONCLUSION: The pre-trained DnCNN available with MATLAB Deep Learning Toolbox can be used for denoising Tc-99m DMSA images, and the performance of DnCNN was found to be superior in comparison with BM3D filter.

PMID:37272279 | DOI:10.1097/MNM.0000000000001712