Nevin Manimala

Environ Sci Pollut Res Int. 2022 Jan 30. doi: 10.1007/s11356-022-18908-6. Online ahead of print.

ABSTRACT

Considering the current global goal of carbon neutrality, the relationship between cultivated land intensive use (CLIU) and carbon emission efficiency (CEE) should be explored to address the global climate crisis and move toward a low-carbon future. However, previous work in this has been conducted at provincial/regional scales and few have identified the spatial correlation between CLIU and CEE at the scale of large river basins. Therefore, this study explored the spatiotemporal characteristics of CLIU, cultivated land carbon emissions (CLCE), and CEE, as well as the spatial correlation between CLIU and CEE in the Yellow River Basin (YRB), China. A comprehensive evaluation model, the Intergovernmental Panel on Climate Change (IPCC) coefficient methodology, existing data envelopment analysis model, and bivariate spatial autocorrelation models were used to analyze statistical data from 2005 to 2017. We found that the overall CLIU and CLCE values in the YRB exhibited a continuous increase; the average carbon emission total efficiency and carbon emission scale efficiency first decreased and then increased, and the average carbon emission pure technical efficiency gradually decreased. Areas of high CLCE were concentrated in eastern areas of the YRB, whereas those of high CLIU, carbon emission total efficiency, carbon emission scale efficiency, and carbon emission pure technical efficiency predominantly appeared in the eastern areas, followed by central and western areas of the YRB. Spatial analysis revealed a significant spatial dependence of CLIU on CEE. From a global perspective, the spatial correlations between CLIU and CEE changed from positive to negative with time. Moreover, the aggregation degree between CLIU and CEE gradually decreases with time, while the dispersion degree increases with time, and the spatial correlation gradually weakens. The local spatial autocorrelation further demonstrates that the number of high-low and low-high clusters between CLIU and CEE gradually increases over time, while the number of high-high and low-low clusters gradually decreased over time. Collectively, these findings can help policymakers formulate feasible low-carbon and efficient CLIU policies to promote win-win cooperation among regions.

PMID:35094255 | DOI:10.1007/s11356-022-18908-6

Risk Anal. 2022 Jan 29. doi: 10.1111/risa.13887. Online ahead of print.

ABSTRACT

Globally, floods as dynamic hydraulic hazard have caused widespread damages to both socioeconomic conditions and environment at various scales. Managing flood and management of water resource is a global challenge under the changing climatic condition. This study assessed flood susceptibility in the Bhagirathi sub-basin, India using entropy information theory and geospatial technology. Twelve flood susceptibility parameters such as land use/land cover, normalized difference vegetation index (NDVI), slope, elevation, geology, geomorphology, normalized difference water index (NDWI), soil, drainage density, average rainfall, maximum temperature, and humidity during monsoon season were utilized to examine flood susceptibility. Receiver operating characteristics (ROC) curve and Leave-One-Out Cross-Validation (LOOCV) techniques were carried out to validate flood susceptibility map. Kappa statistics was also used to check the reliability of the flood susceptibility model. Findings of the study revealed that nearly 45% area of the sub-basin was highly susceptible to flood followed by moderate (29.3%), very high (19%), low (6.9%), and very low (0.2%). These findings also revealed that nearly 92% area in the eastern, north-eastern, and deltaic sub-basin was susceptible to floods. ROC analysis indicated high success (0.932) and prediction (0.903) rates for the susceptibility map while LOOCV (R² being 0.97) and Kappa (k = 0.934) have shown substantial prediction of the model. Hence, the susceptibility maps are useful for the local planners and government organization in designing the early flood warning system, and reducing the human and economic losses. The methodology used in this study is applicable for analyzing flood susceptibility at spatial scales in similar systems.

PMID:35092965 | DOI:10.1111/risa.13887

Rev Bras Ginecol Obstet. 2022 Jan;44(1):55-66. doi: 10.1055/s-0041-1740595. Epub 2022 Jan 29.

ABSTRACT

OBJECTIVE: To summarize the available evidence of TAP Block in efficacy in laparoscopic or robotic hysterectomy.

DATA SOURCES: We searched databases and gray literature for randomized controlled trials in which transversus abdominis plane (TAP) block was compared with placebo or with no treatment in patients who underwent laparoscopic or robot-assisted hysterectomy.

METHOD OF STUDY SELECTION: Two researchers independently evaluated the eligibility of the selected articles.

TABULATION, INTEGRATION, AND RESULTS: Seven studies were selected, involving 518 patients. Early postoperative pain showed a difference in the mean mean difference (MD): – 1.17 (95% confidence interval [CI]: – 1.87-0.46) in pain scale scores (I² = 68%), which was statistically significant in favor of using TAP block, but without clinical relevance; late postoperative pain: DM 0.001 (95%CI: – 0.43-0.44; I² = 69%); opioid requirement: DM 0.36 (95%CI: – 0.94-1.68; I² = 80%); and incidence of nausea and vomiting with a difference of 95%CI = – 0.11 (- 0.215-0.006) in favor of TAP.

CONCLUSION: With moderate strength of evidence, due to the high heterogeneity and imbalance in baseline characteristics among studies, the results indicate that TAP block should not be considered as a clinically relevant analgesic technique to improve postoperative pain in laparoscopic or robotic hysterectomy, despite statistical significance in early postoperative pain scale scores.

CLINICAL TRIAL NUMBER AND REGISTRY: PROSPERO ID – CRD42018103573.

PMID:35092960 | DOI:10.1055/s-0041-1740595

Rev Bras Ginecol Obstet. 2022 Jan;44(1):47-54. doi: 10.1055/s-0041-1740474. Epub 2022 Jan 29.

ABSTRACT

OBJECTIVE: To evaluate the assistance provided to women victims of sexual violence and their participation in the follow-up treatment after the traumatic event, presenting a sociodemographic profile, gynecological background, and circumstances of the event, and reporting the results, acceptance, and side effects of prophylaxis for sexually transmitted infections (STIs) and pregnancy.

METHODS: A retrospective cohort study comprising the period between 2007 and 2016. All women receiving medical care and clinical follow-up after a severe episode of sexual violence were included. Records of domestic violence, male victims, children, and adolescents who reported consensual sexual activity were excluded. The present study included descriptive statistics as frequencies and percentages.

RESULTS: A total of 867 medical records were reviewed and 444 cases of sexual violence were included. The age of the victims ranged from 10 to 77 years old, most of them self-declared white, with between 4 and 8 years of education, and denying having a sexual partner. Sexual violence occurred predominantly at night, on public thoroughfare, being committed by an unknown offender. Most victims were assisted at the referral service center within 72 hours after the violence, enabling the recommended prophylaxis. There was high acceptance of antiretroviral therapy (ART), although half of the users reported side effects. Seroconversion to human immunodeficiency virus (HIV) or to hepatitis B virus (HBV) was not detected in women undergoing prophylaxis.

CONCLUSION: In the present cohort, the profile of victims of sexual violence was low-educated, young, white women. The traumatic event occurred predominantly at night, on public thoroughfare, being committed by an unknown offender. Assistance within the first 72 hours after sexual violence enables the healthcare center to provide prophylactic interventions against STIs and unwanted pregnancies.

PMID:35092959 | DOI:10.1055/s-0041-1740474

Rev Bras Ginecol Obstet. 2022 Jan;44(1):32-39. doi: 10.1055/s-0041-1741408. Epub 2022 Jan 29.

ABSTRACT

OBJECTIVE: To evaluate the improvement in screening accuracy of the Fracture Risk Assessment Tool (FRAX) for the risk of developing osteoporosis among young postmenopausal women by associating with it clinical muscle mass measures.

METHODS: A sample of postmenopausal women was submitted to calcaneal quantitative ultrasound (QUS), application of the FRAX questionnaire, and screening for the risk of developing sarcopenia at a health fair held in the city of São Bernardo do Campo in 2019. The sample also underwent anthropometric measurements, muscle mass, walking speed and handgrip tests. A major osteoporotic fracture (MOF) risk ≥ 8.5% on the FRAX, a classification of medium risk on the clinical guideline of the National Osteoporosis Guideline Group (NOGG), and a QUS T-score ≤ -1.8 sd were considered risks of having low bone mass, and QUS T-score ≤ -2.5sd, risk of having fractures.

RESULTS: In total, 198 women were evaluated, with a median age of 64 ± 7.7 years, median body mass index (BMI) of 27.3 ± 5.3 kg/m² and median QUS T-score of -1.3 ± 1.3 sd. The accuracy of the FRAX with a MOF risk ≥ 8.5% to identify women with T-scores ≤ -1.8 sd was poor, with an area under the curve (AUC) of 0.604 (95% confidence interval [95%CI]: 0.509-0.694) for women under 65 years of age, and of 0.642 (95%CI: 0.571-0.709) when age was not considered. Including data on muscle mass in the statistical analysis led to a significant improvement for the group of women under 65 years of age, with an AUC of 0,705 (95%CI: 0.612-0.786). The ability of the high-risk NOGG tool to identify T-scores ≤ -1.8 sd was limited.

CONCLUSION: Clinical muscle mass measurements increased the accuracy of the FRAX to screen for osteoporosis in women aged under 65 years.

PMID:35092957 | DOI:10.1055/s-0041-1741408

Complement Ther Clin Pract. 2022 Jan 24;46:101536. doi: 10.1016/j.ctcp.2022.101536. Online ahead of print.

ABSTRACT

BACKGROUND: and purpose: A deficiency of vitamin D has been suggested as one of the principal risk factors for uterine fibroids (UFs). We aimed to investigate the effect of vitamin D supplementation on the recurrence of UFs.

MATERIALS AND METHODS: In a randomized, double-blind, placebo-controlled pilot study, women who had undergone hysteroscopic myomectomy from November 2017 to June 2020 were randomly given either vitamin D (1000 IU tablet; n = 55), or placebo (n = 54) daily for 12 months. Both groups were followed and compared in regard of the primary outcomes of the study, which were recurrence rates, size, and numbers of UFs based on three-dimensional transvaginal ultrasound investigation (3D-TVS). Data analysis was performed by the intention-to-treat (ITT) approach.

RESULTS: The mean age of the study participants was 37.9 ± 6.5 years. The two groups did not differ significantly in terms of demographic and pre-intervention clinical characteristics. The administration of vitamin D supplements for one year reduced recurrence rates of UFs by 50% (p = 0.17). Vitamin D also reduced the size of recurrent UFs in the intervention group compared to controls (-7.7 mm), the difference was statistically different (p < 0.001). No adverse effect of vitamin D was reported in the present study.

CONCLUSION: Based on these results, vitamin D appears to be a promising and safe agent in the prevention of recurrence and reduction of the size of recurrent UFs, although further well-designed and appropriately powered studies are required to demonstrate a significant difference in the size and number of recurrent UFs.

PMID:35092948 | DOI:10.1016/j.ctcp.2022.101536

Appl Radiat Isot. 2022 Jan 23;182:110120. doi: 10.1016/j.apradiso.2022.110120. Online ahead of print.

ABSTRACT

Some governorates of Iraq are considered as uranium-contaminated areas. The spread of cancerous tumors injuries was recorded in different parts of Iraq at very high rates. As cancer is closely related to high level of uranium in the blood, this study was conducted on women with breast cancer to evaluate the uranium concentrations in their blood. The aim of the study is to assess the concentration of uranium in the blood Iraqi breast cancer women to establish reference values for the levels of toxic uranium in their blood and the possibility of getting breast cancer. A total of 39 blood samples were collected from breast cancer women and a control group. CR-39 track detector has been used to evaluate the uranium concentration in blood samples by placing a drop of blood on the detectors and calculating the uranium concentrations by irradiating the detectors with a neutron source. Statistical analysis is achieved utilizing SPSS programme. The outcomes show elevated levels of uranium concentration in the blood of women with breast cancer, which was found to be 92±0.6 ngL^-1 compared to the control group (40 ±0.4 ngL^-1), and internationally published data. The results show that the uranium concentration in the blood of breast cancer women is higher than those in the control group and some of the globally published data. This indicated that there is a relationship between the elevated concentrations of uranium in blood and the risk of getting breast cancer.

PMID:35092922 | DOI:10.1016/j.apradiso.2022.110120

Foot (Edinb). 2021 Dec 30;50:101898. doi: 10.1016/j.foot.2021.101898. Online ahead of print.

ABSTRACT

BACKGROUND: Adopting compensatory walking mechanisms by people with foot drop due to traumatic injury of the peroneal nerve costs altered gait kinetics and kinematics. Therefore, orthoses are generally recommended to minimize the deployment of compensatory gait mechanisms.

OBJECTIVES: To investigate the immediate effects of a low-cost, Neoprene Ankle-Foot Orthosis (NAFO) and the thermoplastic ankle-foot orthosis (AFO) with the shoe-only condition on kinematics and kinetics of gait of people with foot drop following peroneal nerve traumatic injury.

METHODS: Seven people with foot drop due to traumatic injury of the peroneal nerve were included in this study. The gait kinematics and kinetics of the participants were investigated in three different conditions: shoe-only, AFO + shoe, and NAFO + shoe using a six-camera, motion-analysis system, and a force platform. A Friedman two-way ANOVA by ranks model was employed to compare different testing conditions.

RESULTS: The ankle angle at the initial contact was significantly different between shoe-only condition and AFO (p < 0.00). The plantarflexion angle in both orthotic designs was reduced significantly compared to the shoe-only condition (p < 0.00). The maximum ankle dorsiflexion angle during the stance phase and maximum knee flexion angle during the stance and swing phases were not statistically significant for all testing conditions (p > 0.00). A significant difference was observed for the 1st-rise of the ground reaction force’s vertical component between the NAFO and the AFO (p < 0.00). Likewise, a significant difference was observed for the 2nd-rise of the ground reaction force’s vertical component between the NAFB and the AFO (p < 0.00).

CONCLUSION: Both orthotic interventions could control the ankle-foot complex during the gait and reduce the employment of compensatory gait mechanisms.

PMID:35092920 | DOI:10.1016/j.foot.2021.101898

Foot (Edinb). 2021 Dec 23;50:101893. doi: 10.1016/j.foot.2021.101893. Online ahead of print.

ABSTRACT

BACKGROUND: This study evaluates the impact of preoperative education on the length of hospital stay after foot and ankle surgery. There are several studies on the benefits of preoperative education prior to hip and knee arthroplasty, especially their role in facilitating early discharges. But studies on the benefits of foot school (Preoperative education) prior to Foot and Ankle surgeries are limited. The aim of this study was to determine if Foot school played a role in expediting early and safe discharges in patients of elective foot and ankle surgeries METHODS: All patients listed for an elective foot and ankle procedure were invited to attend foot school, which consisted of a multi-disciplinary team whose aim was to educate patients about their surgical procedures, rehabilitation and discharge goals. Not all patients attended foot school, as attendance to foot school was recommended but not mandatory for surgery. Data on all foot and ankle surgeries performed in 2019 were collected, and patients were divided into two groups based on their foot school attendance.

RESULTS: 92% of the patients who attended foot school were discharged on the same day. 65% of patients who did not attend foot school returned home the same day. There was a statistically significant difference in the observed mean hours after surgery between the two groups. Patients who attended foot school stayed at the hospital for a lesser duration than those who did not (mean difference = 8.55 h, p-value = 0.004). Early discharges can also increase the turnover of patients for day case procedures and improve cost savings. The cost analysis also showed that a portion of the savings from a reduced hospital stay could run foot school service.

CONCLUSION: Our study demonstrates that preoperative education allows a significantly shorter hospital stay, thereby facilitating early patient discharges. This can improve the patient turnover rate and also would save the hospital cost per procedure. Patients should, therefore, be encouraged to attend Foot school before their surgical procedure.

PMID:35092919 | DOI:10.1016/j.foot.2021.101893

Water Res. 2022 Jan 22;212:118115. doi: 10.1016/j.watres.2022.118115. Online ahead of print.

ABSTRACT

Poor lipid degradation limits low-temperature anaerobic treatment of domestic wastewater even when psychrophiles are used. We combined metagenomics and metaproteomics to find lipolytic bacteria and their potential, and actual, cold-adapted extracellular lipases in anaerobic membrane bioreactors treating domestic wastewater at 4 and 15 °C. Of the 40 recovered putative lipolytic metagenome-assembled genomes (MAGs), only three (Chlorobium, Desulfobacter, and Mycolicibacterium) were common and abundant (relative abundance ≥ 1%) in all reactors. Notably, some MAGs that represented aerobic autotrophs contained lipases. Therefore, we hypothesised that the lipases we found are not always associated with exogenous lipid degradation and can have other roles such as polyhydroxyalkanoates (PHA) accumulation/degradation and interference with the outer membranes of other bacteria. Metaproteomics did not provide sufficient proteome coverage for relatively lower abundant proteins such as lipases though the expression of fadL genes, long-chain fatty acid transporters, was confirmed for four genera (Dechloromonas, Azoarcus, Aeromonas and Sulfurimonas), none of which were recovered as putative lipolytic MAGs. Metaproteomics also confirmed the presence of 15 relatively abundant (≥ 1%) genera in all reactors, of which at least 6 can potentially accumulate lipid/polyhydroxyalkanoates. For most putative lipolytic MAGs, there was no statistically significant correlation between the read abundance and reactor conditions such as temperature, phase (biofilm and bulk liquid), and feed type (treated by ultraviolet light or not). Results obtained by metagenomics and metaproteomics did not confirm each other and extracellular lipases and lipolytic bacteria were not easily identifiable in the anaerobic membrane reactors used in this study. Further work is required to identify the true lipid degraders in these systems.

PMID:35092910 | DOI:10.1016/j.watres.2022.118115