Tag: nevin manimala

J Relig Health. 2025 May 17. doi: 10.1007/s10943-025-02338-y. Online ahead of print.

ABSTRACT

The nurses often face moral challenges and conflicts as their duties are performed. In these situations, professional values and religious well-being support their performance within a specific framework and according to defined ethical principles. The purpose of this study is to examine the impact of ethics-based program on Iranian nurses’ professional values and religious well-being. This was an experimental study conducted in Hajar and Ayatollah Kashani hospitals in Shahrekord (Iran) in 2019-2020. The participants included 130 nurses who were selected by convenience sampling and randomly assigned to the intervention and control groups. The outcome variables were professional values and religious well-being of nurses which measured at the beginning of the study, immediately, and two months after the intervention. Data collection occurred at baseline, immediately and 2 months after the intervention by using The Nurses Professional Values Scale-Revised (NPVS-R) and the Spiritual Well-Being Scale (SWBS). The study’s findings revealed a statistically significant difference in mean changes scores related to professional values and religious well-being between the intervention and control groups following the implementation of the intervention. In conclusion, implementation of the ethics-based program can improve the professional values and religious well-being of nurses.

PMID:40381118 | DOI:10.1007/s10943-025-02338-y

Environ Geochem Health. 2025 May 17;47(6):212. doi: 10.1007/s10653-025-02500-1.

ABSTRACT

The chromite-asbestos mining leaves behind tonnes of toxic waste, contaminating nearby agricultural fields with potentially toxic elements (PTEs). Over time, wind and water erosion spread these pollutants, severely impacting the ecosystem, food chain, and human health. This study evaluates the bioaccessible (stomach and intestinal phases) and leachable forms of PTEs, emphasizing the health and dietary risks associated with PTE pollution in this region. The study result indicates that the leachable and bio-accessible PTEs concentrations in agricultural soil, mainly Cr and Ni, were higher in zone 1 (mine tailings dumping area) and zone 2 (tailings contaminated soil) than zone 3 (uncontaminated soil). PTEs content in rice parts, mainly in boiled rice, showed moderate risk in the SAMOE model from Cr (0.011) and Ni (0.013) while in rice (without husk), it indicated high (class 5) dietary risk. The Fuzzy-TOPSIS, artificial neural network, and Monte-Carlo simulation models all demonstrated that Cr was the major contributor to anthropogenic risk. Compared to adults (5.08E-05), children (1.88E-03) were more vulnerable to total carcinogenic risk via ingestion pathway. Machine learning methods have been implemented to forecast the effects of leachable PTEs on soil-rice systems and possible health hazards associated with consuming food from the chromite-asbestos waste-contaminated zone. The survey-based Fuzzy-DEMATEL technique also showed that consumption of starch and cooked rice were the most crucial factors influencing the population’s health risk. Overall, the implications of the statistical model may aid in assessing potential health hazards and enhancing regulations for ecosystem preservation.

PMID:40381117 | DOI:10.1007/s10653-025-02500-1

Acta Parasitol. 2025 May 17;70(3):110. doi: 10.1007/s11686-025-01043-w.

ABSTRACT

BACKGROUND: Gastrointestinal (GI) parasitism remains a critical challenge in livestock health management, particularly in tropical regions where environmental conditions favor parasite proliferation. This study conducted an 8-year retrospective analysis (2017-2024) of GI parasites in dairy cattle across 11 districts in Bangladesh.

METHODS: Data were sourced from a private veterinary diagnostic laboratory, with a focus on the prevalence, types, and trends of GI parasites as well as associated risk factors. GI parasites were identified using different coproscopic methods including direct smear, flotation, and sedimentation. Statistical analysis was performed using descriptive analysis, followed by Poisson regression.

RESULTS: The most prevalent parasites identified were Schistosoma spp. (57.3%) and Paramphistomum spp. (22.6%), with notable peaks in prevalence during the years 2019 (65%) and 2021 (62%) for Schistosoma spp. and in 2017 (32%) for Paramphistomum spp. Other parasites, such as Balantidium (B.) coli, presented a lower but consistent prevalence (9.8%), whereas Fasciola spp. and Haemonchus spp. were identified less frequently. The analysis revealed that various factors significantly influenced parasite incidence, including seasonal variations, district-specific ecological conditions, and animal-related factors. Statistical analyses, particularly Poisson regression, demonstrated that male cattle (RR: 0.30, 95% CI: 0.230-0.401) had a lower risk of infection with Schistosoma spp. than females, whereas regions with abundant water bodies, such as Manikganj (RR: 11.9, 95% CI: 6.801-20.648, p < 0.001), Mymensingh (RR:7.9, 95% CI: 2.243-27.78, p < 0.01), and Narayanganj (RR: 6.6, 95% CI: 3.867-11.177, p < 0.001), presented higher prevalence rates. Seasonal trends revealed increased prevalence rates during the winter (Schistosoma spp.: RR: 1.5, CI: 1.090-1.919, p < 0.05; Paramphistomum spp.: RR: 1.03, 95% CI: 0.322-3.299; B. coli: RR: 1.2, 95% CI: 0.672-2.151; and Fasciola spp. RR: 2.5, 95% CI: 1.322-4.555), which aligns with periods of more significant water usage and potential exposure to contaminated sources.

CONCLUSION: This study underscores the need for targeted parasite control programs, particularly in high-risk areas, and advocates for improved livestock management practices and regular veterinary interventions to mitigate the economic and health impacts of GI parasites. These findings provide valuable insights for developing tailored parasite management strategies to increase the productivity and well-being of dairy cattle in Bangladesh.

PMID:40381115 | DOI:10.1007/s11686-025-01043-w

Environ Monit Assess. 2025 May 17;197(6):659. doi: 10.1007/s10661-025-14061-y.

ABSTRACT

The problem of human-elephant conflict (HEC) now appears to be one of the greatest challenges in the forest-based mouzas of West Bengal as well as in India. As per the field survey from 2018-2019 to 2020-2021, a total of 277 (16.55%) and 920 (4.21%) mouzas were identified as HEC-affected out of 1674 and 21,832 recognized mouzas in Northern and Southern parts of West Bengal, respectively. Here, the destruction of crops, huts, death and injury of human, livestocks, and even elephants have been increased year after year. Crop-raiding incident is the most common problem among all that occurs during the milky stage and harvesting stage of paddy. Numerous studies have been carried out showing the pattern of HEC incident in some areas of West Bengal, but none of them have tried to identify the HEC risk depending upon crop-raiding incident in this state. Here, it has been tried to examine the mouza-wise HEC risk based on crop-raiding incident in the stated two parts of West Bengal. Two important parameters, the number of crop fields raided and the total number of crop fields present but not raided, were taken into consideration to measure the HEC risk. The result shows that the Jhargram (0.75-0.98), Medinipur (0.68-0.89), and Rupnarayan (0.68-0.89) forest divisions are the highest HEC risk areas in West Bengal. The most dominant factor as determined from the principal component analysis is the lack of fodder and other biological requirements that are one of the basic needs for survival of the elephants within the forest (0.864). The total risk for raiding crop is 3.21 and 2.93 in the two parts of West Bengal. Here, the paddy and vegetables fields are more prone to be raided. Moreover, descriptive statistics were also used to explain the patterns of crop-raiding incidents. The findings may provide a way out for the sustainable management of HEC risk like establishment of micro-habitat, creation of elephant proof trench/electric fences, and rapid plantation of indigenous plant species in the vacant forest areas, thereby helping the policymakers in wildlife conservation.

PMID:40381103 | DOI:10.1007/s10661-025-14061-y

Sleep Breath. 2025 May 17;29(3):187. doi: 10.1007/s11325-025-03339-7.

ABSTRACT

BACKGROUND: The Epworth Sleepiness Scale (ESS) is a brief instrument to identify sleep propensity. However, little is known about the psychometric performance of the Spanish version in university students. The study aimed to study the validity and reliability of the ESS in Colombian university students.

METHODS: A psychometric study was designed with 465 students of health-related careers between 18 and 29 years old (M = 20.48, SD = 2.27); 66.67% of the students were women. A confirmatory factor analysis was conducted, comparisons of scores between men and women, correlations with insomnia (Athens Insomnia Scale, AIS), anxiety (GAD-7), depression (PHQ-9), and sleep hygiene (SHI-10) and sex differential item functioning as indicators of validity and Cronbach’s alpha and McDonald’s omega were calculated as estimators of internal consistency.

RESULTS: The ESS showed a unidimensional structure, similar scores in men and women, statistically significant correlations with AIS, GAD-7, PHQ-9, and SHI-10, without sex differential item functioning, and high internal consistency (Cronabch’s alpha and McDonald’s omega of 0.82).

CONCLUSION: The Spanish version of the ESS presents acceptable validity and reliability indicators in Colombian university students. However, these findings must be corroborated in other samples of Spanish-speaking participants.

PMID:40381086 | DOI:10.1007/s11325-025-03339-7

Lasers Med Sci. 2025 May 17;40(1):227. doi: 10.1007/s10103-025-04488-7.

ABSTRACT

BACKGROUND: Despite extensive research, there is still no consensus on the optimal treatment for Striae distensae (SD).

AIM: To evaluate the efficacy of ablative (short pulse (SP) mode) versus combined ablative and non-ablative (short pulse + smooth (SP + SM) mode) modality of Er: YAG laser for the treatment of SD.

METHODS: This prospective study was conducted on 29 female participants with SD referred to Razi Hospital in 2021. The body areas were divided into left and right side areas. The right side of body areas with SD was treated with SP + SM mode. The left side of body areas with SD was only treated with SP mode. Three months after treatment, clinical improvement was assessed based on dermatologist assessment and patients’ opinion.

RESULTS: The participants were middle-aged women with SD on the chest, abdomen, thighs, knees, or arms. SD in both study groups (SP + SM mode versus SP mode alone) showed improvement after treatment. Nonetheless, there was no statistically significant difference between the two study groups regarding the clinical improvement based on dermatologist assessment (p = 0.279) and improvement of striae based on patient opinion (p = 0.208).

CONCLUSION: In conclusion, we demonstrated that both ablative (SP mode) and combined ablative and non-ablative (SP + SM mode) strategies of Er: YAG laser are efficient for the treatment of SD. However, we failed to show any superiority for combined ablative and non-ablative (SP + SM mode) compared to ablative (SP mode) modality.

PMID:40381084 | DOI:10.1007/s10103-025-04488-7

Discov Oncol. 2025 May 17;16(1):794. doi: 10.1007/s12672-025-02636-7.

ABSTRACT

BACKGROUND: Colorectal carcinogenesis involves dynamic interactions between genetic susceptibility and cellular heterogeneity, yet current studies rarely disentangle causal genes from passive associations. While GWAS have mapped numerous risk loci, only a minority colocalize with eQTL/pQTL. A multi-omics framework combining single-cell transcriptomics, transcriptomics, proteomics, and MR is urgently needed to resolve cell-type-specific drivers of colorectal cancer pathogenesis.

METHODS: We integrated GWAS data, eQTL data, pQTL data, and single-cell RNA sequencing differential gene expression profiles from public databases. Subsequent batch Two-sample Mendelian randomization and further SMR analysis aimed to identify key genes in the pathogenesis of colorectal cancer.

RESULTS: Cluster analysis identified 4909 DEGs across various cell types. We discovered that 428 DEGs had a causal association with colorectal cancer through eQTL, of which 38 genes met the FDR statistical standards, and four of these genes (CTSF, PCSK7, LYZ, LMAN2L) also had causal associations through pQTL. SMR analysis confirmed the reliability of PCSK7 as a disease target.

CONCLUSION: By integrating single-cell data, transcriptomic data, proteomic data and GWAS data for MR analysis, we identified CTSF, PCSK7, LYZ, LMAN2L as potential targets for colorectal cancer.

PMID:40381082 | DOI:10.1007/s12672-025-02636-7

J Community Health. 2025 May 17. doi: 10.1007/s10900-025-01476-4. Online ahead of print.

ABSTRACT

This study aimed to determine diet, physical activities, and the frequency and risk factors for body weight problems in children aged between 5 and 13 who attend public primary schools in Constantine, Algeria. A total of 811 children (403 girls and 408 boys) enrolled in three random primary schools in Constantine took anthropometric measurements to calculate body mass index (BMI = weight/size). A questionnaire was created to collect information about the children’s lifestyles, which was completed online by their parents. Obesity and overweight were determined according to the standards of the World Health Organization (WHO). A statistical analysis was conducted to identify risk factors for overweight and obesity. The results showed that overweight affects 1.726% of children (57.15% boys and 42.85% girls). The results also showed a 0.616% prevalence of obesity (60% boys, 40% girls). In addition to that, the results of this study revealed that 72.133% of the children are underweight (51.96% boys, 48.04% girls), and 25.524% of them have normal weight (44.92% boys, 55.08% girls). In risk factor analysis, the results show that body weight problems are associated with different factors like sex, age group (8-10 years old), number and composition of meals, and lack of physical activity. Body weight problems are a severe condition that deserves significant healthcare expenses, and for that, urgent protective measures are required. The promotion of a healthy diet and regular physical activity is a top priority in body weight problem prevention, especially for children.

PMID:40381075 | DOI:10.1007/s10900-025-01476-4

Oral Maxillofac Surg. 2025 May 17;29(1):102. doi: 10.1007/s10006-025-01399-3.

ABSTRACT

AIM: The aim of this study is to assess the efficacy of the stereolithographic surgical guide in reducing intraoperative and postoperative complication during lateral sinus lift operation.

MATERIALS AND METHODS: A parallel randomized controlled prospective clinical study was conducted on fourteen patients requiring thirty dental implants in the posterior maxilla and diagnosed with reduced vertical bone height. Lateral Maxillary Sinus Lift procedure with simultaneous implant placement was performed to all patients. Stereolithographic surgical guides for lateral window osteotomy and implant drilling and placement were used in the study group, while lateral osteotomy and implant drilling and placement was done freehand in the control group. A cone beam computed tomography was taken immediately and six months post-sinus lifting. Intraoperative and postoperative complications were assessed, pain and edema were assessed using visual analogue scale and vertical bone was assessed using fusion module of cone beam computed tomography.

RESULTS: All dental implants demonstrated high survival rates with no statistically significant difference observed in intraoperative or postoperative complications. In terms of new vertical bone gain, both groups exhibited satisfactory and successful outcomes. Concerning pain, there was no statistically significant difference between the two groups except after two days, the study group showed statistically significantly lower pain score than the control group. While regarding the severity of edema, the study group showed statistically significantly higher prevalence of moderate and severe edema than control group which showed higher prevalence of mild edema.

CONCLUSION: According to the current study it has been concluded that there was no remarkable difference between the outcomes of both methods. The study protocol and its consent form were approved by the ethical committee of Suez Canal University (No.432/2021); and registered retrospectively on 23 April 2024 on PACTR (PACTR20240875463218) (pactr.samrc.ac.za/TrialDisplay.aspx?TrialID = 30442).

PMID:40381068 | DOI:10.1007/s10006-025-01399-3

Int Ophthalmol. 2025 May 17;45(1):193. doi: 10.1007/s10792-025-03558-7.

ABSTRACT

PURPOSE: To compare visual acuity outcomes of two monofocal IOL models, a zero-aberration monofocal IOL (Envista MX60E; Bausch and Lomb) and a monofocal plus IOL (Eyhance DIB00; Johnson and Johnson), in eyes undergoing combined cataract surgery and Descemet membrane endothelial keratoplasty (DMEK) (triple DMEK).

METHODS: Retrospective, single-center case series of 91 eyes (66 patients) undergoing triple DMEK with either IOL between 2019 and 2023 at a tertiary academic center. Eyes were divided into 2 groups: zero-aberration IOL (49 eyes) and monofocal plus IOL (42 eyes). Among these, 20 eyes received a zero-aberration IOL, and 26 eyes received a monofocal plus IOL in both eyes. Visual acuity measurements at 3-6 months and 6-12 months postoperatively included uncorrected distance, intermediate, and near (UDVA, UIVA, UNVA) and distance-corrected distance, intermediate, and near (CDVA, DCIVA, DCNVA) visual acuities for monocular (Uni) and binocular (Bi) assessments. Patients were administered the Intraocular Lens Satisfaction questionnaire to assess their level of spectacle independence at the 3-6 month visit. Statistical analysis was performed using Wilcoxon rank-sum and Fisher’s exact tests.

RESULTS: UDVA_Uni, CDVA_Uni, and UNVA_Uni were favorable and comparable between the two groups. At the 3-6 month timepoint, the Eyhance group had significantly better UIVA_Uni (0.17 ± 0.12 vs. 0.23 ± 0.13, p = 0.03), DCIVA_Uni (0.23 ± 0.08 vs. 0.31 ± 0.08, p < 0.001), and DCNVA_Uni (0.36 ± 0.09 vs. 0.40 ± 0.08, p = 0.04). However, at 6-12 months, all six VA measurements were similar between the 2 groups. Bilateral cases at the 3-6 month timepoint demonstrated superior DCNVA_Bi in the Eyhance group versus the Envista group (0.31 ± 0.08 vs. 0.41 ± 0.03, p = 0.008). The spherical equivalent refractive error (- 0.51 ± 0.94D vs. – 0.55 ± 1.05D, p = 0.89) for all eyes and inter-eye refractive error in the binocular subgroup (0.29 ± 1.36D vs. 0.42 ± 1.11D, p = 0.80) was similar for both groups. Postoperative complications and patient satisfaction were comparable between the two groups.

CONCLUSION: Both IOLs can provide favorable corrected and uncorrected VA in triple DMEK eyes. Eyhance may provide better DCIVA_Uni and UIVA_Uni in single eyes and better DCNVA_Uni/Bi in all eyes up to six months postoperatively.

PMID:40381067 | DOI:10.1007/s10792-025-03558-7