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Nevin Manimala Statistics

Feasibility of a Psychoeducational Intervention for Empowering Parents to Optimise Feeding Practices in China: A Randomised Controlled Feasibility Trial

Matern Child Nutr. 2026 Mar;22(1):e70155. doi: 10.1111/mcn.70155.

ABSTRACT

Parental feeding practices play a crucial role in preventing childhood obesity and promoting healthy eating habits. However, few interventions are specifically designed to improve these practices. We aimed to assess the feasibility and preliminary effects of a novel psychoeducational intervention, Empower Parents to Optimise Feeding Practices (EPO-Feeding), tailored to enhance parental feeding practices in China. A parallel-arm feasibility randomised controlled trial (RCT) was conducted in two public kindergartens in Yangzhou, China. Participants were randomly assigned to the intervention group (EPO-Feeding programme plus usual care) or control group (usual care). Data were collected at baseline, post-intervention, and 1 month after intervention. Descriptive statistics assessed feasibility and acceptability, while analysis of variance for repeated measures and generalised estimating equations analysed continuous and categorical outcomes across time points, respectively. Within 2 weeks, 131 parents expressed interest, and 84 eligible participants were randomly assigned. Module attendance and retention rates were high, with 83.3% (n = 35) completing all sessions and 97.6% (n = 82) completing all measurements. Satisfaction surveys indicated high acceptability. Statistically significant improvements were observed in the intervention group, including increased encouragement of healthy eating and monitoring, reduced pressure to eat and food as rewards, improved weight accurate perception, and enhanced parenting efficacy (p < 0.05). However, no significant effects were found in long-term outcomes, including children’s eating behaviours and weight status. This study demonstrates high feasibility and acceptability of the EPO-Feeding programme and suggests its potential to support Chinese parents’ feeding strategies. A full-scale RCT is recommended. Trial registration. It was registered with ClinicalTrials.gov (NCT06181773), 20/11/2023.

PMID:41503735 | DOI:10.1111/mcn.70155

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Nevin Manimala Statistics

Evaluating the Effect of Random Multi-Donor Pooling on the Nutritional Variability in Donor Human Milk Using Computer Modeling

Matern Child Nutr. 2026 Mar;22(1):e70158. doi: 10.1111/mcn.70158.

ABSTRACT

Protein and fat concentrations in donor human milk (DHM) can vary twofold to threefold and are influenced by the number of unique donors per pool. The aim of this study was to broadly characterize how the number of donors (2-10) randomly combined into a pool during milk bank processing influenced the variability of macronutrients, vitamins, minerals, and bioactive factors in DHM. The minimum number of donors required for 80% of the pools to meet pre-defined targets for true protein, fat, and disialyllacto-N-tetraose (DSLNT) was also evaluated. Monte Carlo simulation was used to create models that accounted for donor lifetime donation volume and milk bank production constraints. Variability in nutrients was quantified as a Nutrient Inequality Index (NII) which was computed as the ratio of the 90th percentile to the 10th percentile for each simulation. Random multi-donor pooling of 2-10 donors produced lower variability in DHM macronutrients than most vitamins and minerals. A priori targets of 0.9 g/dL of true protein, 3.5 g/dL of fat, and 210 µg/L of DSLNT could not be achieved with any random pooling scenario. The NII for lactose stabilized at less than 1.1 when there were 3+ donors per pool, while the NII for fat and true protein stabilized at less than 1.3 when there were 5+ donors per pool. The NII exceeded 1.5, even at 10 donors per pool, for several micronutrients including zinc, copper, sodium, iron, biotin, riboflavin, B6, B12, and pantothenic acid.

PMID:41503733 | DOI:10.1111/mcn.70158

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Nevin Manimala Statistics

These mesmerizing patterns are secretly solving hard problems

Tessellations aren’t just eye-catching patterns—they can be used to crack complex mathematical problems. By repeatedly reflecting shapes to tile a surface, researchers uncovered a method that links geometry, symmetry, and problem-solving. The technique works in both ordinary flat space and curved hyperbolic worlds used in theoretical physics. Its blend of beauty and precision could influence everything from engineering to digital design.
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Nevin Manimala Statistics

Statistical optimization of fermentation conditions for enhanced production of Nattokinase from Bacillus subtilis MM26

BMC Biotechnol. 2026 Jan 7. doi: 10.1186/s12896-025-01093-y. Online ahead of print.

NO ABSTRACT

PMID:41501758 | DOI:10.1186/s12896-025-01093-y

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Nevin Manimala Statistics

Bridging the gap: a survey of resident physicians’ needs for cross-sectional anatomy education and a collaborative teaching framework

BMC Med Educ. 2026 Jan 7. doi: 10.1186/s12909-026-08567-3. Online ahead of print.

ABSTRACT

BACKGROUND: Cross-sectional anatomy is essential for clinical imaging interpretation, yet many medical curricula lack systematic training for clinical students. This study assessed needs among resident physicians and proposed a collaborative education framework.

METHODS: A cross-sectional survey of 130 resident physicians from Zhejiang University-affiliated hospitals (June-August 2025) evaluated knowledge gaps, clinical challenges, and preferences using descriptive statistics, chi-square tests, and logistic regression.

RESULTS: Of 130 respondents (53% female, 58% aged 26-30), 74% reported no formal cross-sectional anatomy training, despite 88% citing high clinical needs. Top challenges included anatomical positioning (45%), with surgery residents showing greatest urgency (95%). Preferences favored clinical-basic science collaboration (64% “very important”), blended online-offline formats (57%), and 3D imaging (71%).

CONCLUSIONS: Significant educational gaps persist in cross-sectional anatomy, underscoring the need for collaborative models integrating clinical cases and technology. This framework can guide curriculum reforms to enhance imaging competency and patient safety in global medical education.

PMID:41501742 | DOI:10.1186/s12909-026-08567-3

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Nevin Manimala Statistics

Surgical site infection and associated factors among women who underwent cesarean delivery at Gandhi Memorial Hospital, Addis Ababa, Ethiopia

BMC Pregnancy Childbirth. 2026 Jan 7. doi: 10.1186/s12884-026-08633-0. Online ahead of print.

ABSTRACT

BACKGROUND: Surgical site infection continues to be among the most serious postoperative complications of cesarean delivery, leading to maternal morbidity and additional healthcare cost. Despite the rising trend of cesarean deliveries, evidence on the magnitude and risk factors of surgical site infection in local hospitals in Ethiopia remains limited. This study aimed to assess the magnitude and associated factors of surgical site infection among women who underwent cesarean delivery at Gandhi Memorial Hospital, Addis Ababa, Ethiopia.

METHODS: An institution-based retrospective cross-sectional study was conducted from 25 August to 15 September 2025 among women who underwent cesarean delivery at Gandhi Memorial Hospital Addis Ababa, Ethiopia between 1 May 2023 and 30 April 2025. A total of 485 medical records were selected using a systematic sampling technique. Data were collected from women’s medical records via a structured checklist and analyzed using Statistical Package for Social Science (SPSS) version 25. Descriptive statistics were used to summarize the data, and bivariable and multivariable logistic regression analyses were performed. Statistical significance was declared at a p- value < 0.05 with a 95% CI.

RESULTS: Among the reviewed records, 31 (6.4%; 95% CI: 4.49-8.36) women developed surgical site infection. Repeated digital vaginal examination (AOR = 2.44 (1.41, 5.19) increases the risk of bacterial introduction; delayed timing of prophylactic antibiotic (AOR = 2.32 (1.23, 4.29) reduces protective coverage at the time of incision; absence of vaginal cleansing right before surgery (AOR = 3.75 (1.26, 11.17) likely increases bacterial load and postoperative hemoglobin level < 11 g/dl (AOR = 5.16 (1.76, 11.19)) may reduce immune capacity. All were significantly associated with surgical site infection.

CONCLUSION: This study found lower surgical site infection rates compared to previous Ethiopian studies; however, it remains a critical postoperative concern. Reducing frequent digital vaginal examinations, ensuring timely prophylactic antibiotics, promoting preoperative vaginal cleansing, and maintaining adequate maternal hemoglobin levels are critical to further reduce the risk of SSI. The retrospective nature of the study limits assessment of some factors, including operating room conditions.

PMID:41501740 | DOI:10.1186/s12884-026-08633-0

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Nevin Manimala Statistics

The efficacy of super-lubricous Foley catheters in indwelling catheterization: a randomized controlled trial

BMC Urol. 2026 Jan 7. doi: 10.1186/s12894-025-02035-8. Online ahead of print.

ABSTRACT

OBJECTIVE: This randomized controlled trial evaluated the clinical efficacy of super-lubricous Foley catheters in reducing urethral complications during indwelling catheterization. Focusing on addressing friction-induced injuries, the study assessed four outcomes: 1) urethral adverse reactions; 2) urethral trauma and inflammatory responses; 3) patient comfort; and 4) post-removal voiding symptoms.

METHODS: A total of 114 patients from a tertiary hospital (December 2023-June 2024) were randomly allocated into two arms: 57 individuals in the experimental arm were treated with super-lubricous Foley catheters, whereas the same number in the control arm received conventional catheters. Primary outcomes included bladder irritation and urethral pain. Secondary outcomes encompassed urethral injury (red blood cells and epithelial cells), inflammation (white blood cells), comfort metrics (activity restriction, sleep disturbance, anxiety), and voiding parameters (dysuria, urinary hesitation, incomplete bladder emptying and lower abdominal pain).

RESULTS: The baseline data revealed no statistically meaningful differences between the two groups. (all P > 0.05). The experimental group demonstrated significantly lower overall rates of bladder irritation (31.6% vs. 50.9%, P < 0.05) and urethral pain during catheterization (14.0% vs. 31.6%, P < 0.05). Notably, urinary epithelial cells (median 6 vs. 13.5/HP) and leukocytes (31 vs. 81/μL) were reduced in the experimental group (P < 0.05). Activity restriction rates decreased significantly (42.1% vs. 68.4%, P < 0.05), and first void volume improved (200 vs. 150 mL, P < 0.05). There were no meaningful differences between groups in the occurrence of the four urination-related symptoms-including dysuria, urinary hesitation, incomplete bladder emptying, and lower abdominal pain (all P > 0.05).

CONCLUSION: Super-lubricous Foley catheters effectively mitigate bladder irritation, urethral trauma, and inflammation while enhancing patient mobility. However, they show limited efficacy in alleviating post-removal voiding dysfunction. These findings support the clinical adoption of super-lubricous Foley catheters for reducing catheterization-related complications.

TRIAL REGISTRATION: This study was a randomized controlled trial registered at Chinese Clinical Trial Registry (ChiCTR2300078483, https://www.chictr.org.cn/) on 11 December 2023.

PMID:41501738 | DOI:10.1186/s12894-025-02035-8

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Nevin Manimala Statistics

Public awareness of oral cancer in Palestine: a web-based cross-sectional survey

BMC Oral Health. 2026 Jan 7. doi: 10.1186/s12903-025-07589-5. Online ahead of print.

ABSTRACT

BACKGROUND: Oral cancer remains a major global health concern with low survival in late stages. In Palestine, the burden is amplified by delayed detection and limited healthcare resources, yet public awareness has never been assessed. This study aimed to evaluate knowledge and awareness of oral cancer risk factors, symptoms, and preventive measures among Palestinian adults.

METHODS: A cross-sectional, web-based survey was conducted between May and August 2025 using an anonymous bilingual (Arabic/English) questionnaire adapted from a validated Middle East-North Africa tool. Palestinian adults aged ≥ 18 years were eligible, excluding health-related professionals and students. Snowball sampling via social media produced 753 valid responses. Data were analyzed using descriptive statistics, chi-square tests, and multivariable logistic regression to identify predictors of good knowledge (≥ 4 correct responses per domain).

RESULTS: Participants were predominantly female (66.3%) and university educated (72.6%). Overall, 46.7% demonstrated good knowledge of risk factors, 32.5% of symptoms, and 53.7% of protective measures. Awareness was highest for tobacco (79.2%) and lowest for HPV infection (38.5%) and alcohol-containing mouthwash (34.1%). Females and university graduates consistently showed better knowledge across all domains (p < 0.001). Current smokers had significantly poorer awareness of risk and protective factors (p < 0.001). Logistic regression identified female gender (OR = 1.59-1.65) and university education (OR = 2.22) as independent predictors of higher knowledge, while current smoking predicted lower protective awareness (OR = 0.65). Receiving oral cancer education from a dentist was the strongest predictor of good knowledge across all domains (risk factors OR = 3.79; symptoms OR = 2.16; protective measures OR = 1.95; all p < 0.01).

CONCLUSION: The surveyed Palestinian sample demonstrated limited awareness of oral cancer, especially regarding symptoms and less-recognized risk factors. Dentist-led education markedly improves knowledge, suggesting that integrating standardized awareness materials into routine dental visits and community campaigns could strengthen early detection and national prevention efforts.

PMID:41501724 | DOI:10.1186/s12903-025-07589-5

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Nevin Manimala Statistics

Development and validation of nomograms for predicting depression and suicidal ideation in stroke survivors: a community-based study

BMC Psychiatry. 2026 Jan 7. doi: 10.1186/s12888-025-07767-3. Online ahead of print.

NO ABSTRACT

PMID:41501723 | DOI:10.1186/s12888-025-07767-3

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Nevin Manimala Statistics

Sports as a pathway to wellness: sports and health-related quality of life among adolescents in Germany (a cross-sectional analysis from GeWIT Study)

BMC Public Health. 2026 Jan 7. doi: 10.1186/s12889-025-25902-3. Online ahead of print.

ABSTRACT

BACKGROUND: Health-Related Quality of Life (HRQoL) comprises individuals’ perceived health status, including physical, psychological and social well-being. Investigating aspects that put adolescents at a good quality of life is important for designing public health efforts to promote their health. This study examined the associations between sports participation and HRQoL among adolescents in Witten, Germany.

METHOD: This cross-sectional study was conducted from November 2021 to February 2022. Tenth-grade students from nine secondary schools in Witten, who were at least 15 years old, were included (n = 649). Data were collected using a self-report written questionnaire. Sports participation was defined as participation in any sports outside of school. Performance-based sport types, such as individual- and team-based sports were also explored. HRQoL (KIDSCREEN-27) was characterized as subjective perceptions of five multidimensional constructs: (1) physical and (2) psychological well-being, (3) parent relations and autonomy (4) social support and peers and (5) school environment. T-values across five dimensions were used to assess HRQoL, with higher values indicating better HRQoL. Descriptive statistics were calculated. Multiple linear regression between sport participation and HRQoL, as well as performance-based sport types and HRQoL adjusted for covariates, were performed. Analyses were adjusted for gender, age, Body Mass Index, subjective socio-economic status, migration background and frequency of physical activity.

RESULTS: Data from 561 participants were included in the analysis. Students who participated in sports showed better physical well-being than adolescents who where inactive in sports (difference (B) = 4.92 (p < 0.001)). Joining all types of sports was significantly associated with better physical well-being than being sport inactive, but individual- and team-based sports showed the highest increase (difference (B) individual-based sports = 3.52 (p < 0.001), difference (B) team-based sports = 6.14 (p < 0.001), difference (B) individual- and team-based sports altogether = 9.06 (p < 0.001)). Engaging in individual-based sports alone was associated with poorer parent relations and autonomy (difference (B) = -2.40, (p = 0.048)).

CONCLUSION: This is the first study to investigate the association between sports participation and HRQoL among adolescents in Witten, Germany. Engagement in sports was positively associated with physical well-being. Participations in individual and team sports outside school could be valuable for adolescents to improve physical activity.

PMID:41501714 | DOI:10.1186/s12889-025-25902-3