Categories
Nevin Manimala Statistics

Current state and potential of hospitals for automated healthcare-associated infection surveillance: data from 24 European countries, 2022 to 2023

Euro Surveill. 2026 May;31(19). doi: 10.2807/1560-7917.ES.2026.31.19.2500736.

ABSTRACT

BACKGROUNDAlthough electronic health records are increasingly used for automated surveillance (AS) of healthcare-associated infections (HAIs), implementation is still a challenge. To develop more targeted implementation initiatives across Europe, knowledge about the current state of AS and potential to implement AS systems is needed.AIMTo assess the adoption and feasibility of AS based on the 2022-2023 European Centre for Disease Prevention and Control (ECDC) Point Prevalence Survey (PPS).METHODSThe 2022-2023 ECDC PPS included questions on the degree of AS and digital data storage for seven HAIs. Descriptive analyses of the responses were performed and stratified by geographic region and hospital characteristics. Categorical variables were analysed as such and converted to ordinal scales.RESULTSOverall, 992 hospitals from 24 European countries participated. Across all seven HAIs, fully manual surveillance was the most common method (from healthcare-associated pneumonia (HAP) 38.8% to Clostridioides difficile infection (CDI) 45.4%). A considerable proportion, i.e. 19.3% (HAP) to 29.8% (CDI), employed some form of automation (automated denominator 5.3-11.3%; semi-automated 12.2-16.9%; fully automated 1.8-2.9%). Many hospitals not employing AS had required source data digitally stored. Generally, tertiary hospitals had higher levels of automation and digital data storage compared with other hospital types. Smaller hospitals (≤ 250 beds) had lower levels of automation, but a similar level of digital data storage compared with larger hospitals.CONCLUSIONThis study highlights variability in AS implementation and digital potential across European hospitals and underscores the need for targeted strategies to advance AS adoption and optimise surveillance.

PMID:42141872 | DOI:10.2807/1560-7917.ES.2026.31.19.2500736

Categories
Nevin Manimala Statistics

Product- and schedule-specific vaccine effectiveness against invasive Haemophilus influenzae serotype b (Hib) disease, The Netherlands, 2005 to 2023

Euro Surveill. 2026 May;31(19). doi: 10.2807/1560-7917.ES.2026.31.19.2500699.

ABSTRACT

BACKGROUNDInvasive Haemophilus influenzae type b (iHib) disease incidence in < 5-year-olds decreased after vaccine introduction but increased between 2011 and 2023 in the Netherlands. The National Immunisation Programme changed products in 2011 (from DTaP-IPV/Hib to DT3aP-HBV-IPV/Hib) and 2018 (to DT5aP-HBV-IPV-Hib) and schedule from 3 + 1 to 2 + 1 doses in 2020.AIMWe aimed to estimate overall, product- and schedule-specific vaccine effectiveness (VE) against iHib disease to inform vaccination strategies.METHODSWe conducted a matched case-control study extracting iHib cases born ≥ 2005 and aged 6-119 months from 2005-2023 national reference laboratory data. We selected 10 controls per case matched on birth date and sex from the population register and obtained vaccination data from the vaccination registry. Using conditional logistic regression, we estimated matched odds ratios (mOR) and VE among 6-10-month-olds (eligible only for the primary series) and 11-119-month-olds.RESULTSWe included 250 iHib cases and 2,487 controls. Among children aged 11-119 months, VE against iHib of the full schedule was 96% (95% CI: 88-99), 95% (95% CI: 91-97) and 98% (95% CI: 94-99) for any DTaP-IPV/Hib, DT3aP-HBV-IPV/Hib and DT5aP-HBV-IPV-Hib, respectively. It was 97% (95% CI: 93-99) for 2 + 1, 96% (95% CI: 93-98) for 3 + 1 doses, and > 95% for the respective primary series. No differences in VE by time since vaccination were observed between products or schedules.CONCLUSIONChanges in VE against iHib after recent product or schedule changes do not explain the increasing iHib incidence. The high VE supports pursuing optimal vaccination coverage.

PMID:42141871 | DOI:10.2807/1560-7917.ES.2026.31.19.2500699

Categories
Nevin Manimala Statistics

Influenza vaccination attenuates acute myocardial infarction and stroke risk following influenza infection: a register-based, self-controlled case series study, Denmark, 2014 to 2025

Euro Surveill. 2026 Apr;31(13). doi: 10.2807/1560-7917.ES.2026.31.13.2500706.

ABSTRACT

BACKGROUNDInfluenza infection is a recognised trigger of acute myocardial infarction (AMI) and stroke, but whether influenza vaccination modifies this risk remains unclear.AIMWe aimed to quantify the short-term cardiovascular risk after laboratory-confirmed influenza infection and assess whether vaccination attenuates it.METHODSWe conducted a nationwide self-controlled case series study using Danish health registries (2014-2025) and included individuals aged ≥ 40 years with a first-ever hospital admission for AMI or stroke within ± 365 days of a PCR-confirmed influenza infection. We defined days 1-7 after specimen date as the risk period and excluded a 14-day pre-exposure period to reduce reverse causality, where influenza testing might be prompted by cardiovascular disease symptoms. We linked testing, hospitalisation, vaccination and mortality data deterministically via unique personal identifiers. We estimated incidence rate ratios (IRRs) and 95% confidence intervals (CI) with conditional Poisson regression.RESULTSAmong 1,221 individuals with a first-ever AMI (n = 429; 35%) or stroke (n = 792; 65%), median age was 75 years (interquartile range: 66-82); 561 (46%) were female. After calendar-month adjustment, the IRR for cardiovascular events during the risk period was 3.5 (95% CI: 2.6-4.7), higher for AMI (IRR = 4.7; 95% CI: 3.1-7.4) than stroke (IRR = 2.9; 95% CI: 2.0-4.2). Prior influenza vaccination during the same influenza season, recorded in 610 (50%) episodes, reduced the excess risk of AMI or stroke associated with influenza infection (interaction p = 0.020).CONCLUSIONSInfluenza infection conferred a transiently increased risk of first-time AMI and stroke. Vaccination substantially attenuated this risk, supporting its role in preventing cardiovascular complications after breakthrough infection.

PMID:42141868 | DOI:10.2807/1560-7917.ES.2026.31.13.2500706

Categories
Nevin Manimala Statistics

Inequalities in adolescent HPV, Td/IPV and MenACWY vaccination coverage by socio-economic status: an ecological study, England, 2017 to 2024

Euro Surveill. 2026 Apr;31(13). doi: 10.2807/1560-7917.ES.2026.31.13.2500586.

ABSTRACT

BACKGROUNDMany countries use school-based vaccination for adolescent vaccination; it has been shown to reduce inequities in uptake compared with other delivery routes. In England, coverage for human papillomavirus (HPV), meningococcal groups A, C, W and Y (MenACWY) and tetanus, diphtheria and inactivated polio virus (Td/IPV) vaccine programmes exceeded 80% before the COVID-19 pandemic. However, recent data show declining uptake.AIMThis study examined the relationship between socio-economic deprivation and coverage over time.METHODSWe conducted an ecological analysis of first-dose coverage for HPV (females and males), MenACWY and TdIPV in adolescents across 150 local authorities in England from 2017 to 2024. Coverage data were linked to 2025 Index of Multiple Deprivation (IMD) scores. Associations between IMD quintile, academic year and vaccination coverage were estimated using beta regression models.RESULTSBetween 2020 and 2024, lower coverage was consistently associated with higher deprivation, and differences in coverage between the most and least deprived IMD quintiles more than doubled. In 2024 these differences were 17.7%, 18.2%, 16∙8% and 16.9% for HPV (females), HPV (males), MenACWY and Td/IPV, respectively. The consistency of these findings suggests the effect of deprivation on coverage is not vaccine-specific.CONCLUSIONWe demonstrated a consistent and strengthening association between coverage and deprivation across multiple adolescent school-based vaccination programmes in England over time. Contributory factors may be numerous, and further research is needed to understand which factors are driving trends for different populations. Addressing these inequalities will require sustained targeted interventions to improve awareness of and access to vaccination.

PMID:42141866 | DOI:10.2807/1560-7917.ES.2026.31.13.2500586

Categories
Nevin Manimala Statistics

Decreases in influenza vaccination coverage among nursing home healthcare workers and in measures to promote influenza vaccination, France, 2007/08 to 2024/25

Euro Surveill. 2026 Mar;31(12). doi: 10.2807/1560-7917.ES.2026.31.12.2500628.

ABSTRACT

BACKGROUNDVaccination of residents and healthcare workers (HCWs) against influenza in nursing homes is an important prevention strategy.AIMTo describe trends in influenza vaccination coverage (VC) among HCWs working in nursing homes in France and measures implemented to support vaccination campaigns from 2007 to 2025, and to identify effectiveness of these measures.METHODSWe analysed data from seven nationwide cross-sectional studies conducted between seasons 2007/08 and 2024/25 and performed multivariate analysis using negative binomial regressions, to identify determinants.RESULTSNational influenza VC among HCWs decreased from 37.2% (95% CI: 35.7-39.4) in 2007/08 to 24.2% (95% CI: 23.2-25.1) in 2024/25 (mean: 39,740 HCWs per season, 6 seasons). Vaccination coverage disparities by category of HCWs (2024/25 VC of physicians: 56.3%; nurses: 34.2%; nursing assistants: 19.3%) were observed throughout the period. Measures to promote influenza vaccination were less frequently implemented over time: support of vaccination campaigns by the management team (from 2018/19: 89% to 2024/25: 52%), implementation of collective (68% to 49%) or individual information sessions (19% to 9%), distribution of information on influenza vaccines (64% to 53%) or influenza (83% to 69%). Seven measures exhibited effectiveness in 2018/19 compared to only four in 2024/25, which had less effectiveness. Management teams highlighted the strong reluctance of HCWs to receive influenza vaccination.CONCLUSIONSInfluenza VC among HCWs in nursing homes is marked by disparities among professional categories. To mitigate the decline in VC among HCWs, it is essential to implement effective measures to support the campaigns.

PMID:42141864 | DOI:10.2807/1560-7917.ES.2026.31.12.2500628

Categories
Nevin Manimala Statistics

Rapid spread of MPXV clade Ib with high genetic relatedness among men who have sex with men, Berlin, Germany, week 50 2025 up to week 10 2026

Euro Surveill. 2026 Mar;31(12). doi: 10.2807/1560-7917.ES.2026.31.12.2600235.

ABSTRACT

Following the first detection of monkeypox virus (MPXV) clade Ib in Berlin, Germany, in December 2025, clade Ib rapidly predominated over clade IIb among notified mpox cases. The 35 clade Ib cases were primarily due to autochthonous transmission, with high genetic relatedness among strains circulating in men in Berlin, despite no identified epidemiological links. Sexual contact between men was reported as a potential source of infection in 28 cases, while for the remaining seven cases this information was unknown.

PMID:42141863 | DOI:10.2807/1560-7917.ES.2026.31.12.2600235

Categories
Nevin Manimala Statistics

Assessing the annual burden of tick-borne encephalitis virus infections, north-east Italy, 2017 to 2024

Euro Surveill. 2026 Apr;31(17). doi: 10.2807/1560-7917.ES.2026.31.17.2500733.

ABSTRACT

BACKGROUNDTick-borne encephalitis (TBE), a neuroinvasive disease in humans, is endemic in north-east Italy and nationally notifiable since 2017. Domestic TBE incidence, although low, has increased in recent years while TBE vaccination coverage remains < 10%.AIMWe aimed to estimate the burden of TBE virus (TBEV) infections in north-east Italy (Triveneto) in 2017-2024.METHODSWe estimated disability-adjusted life years (DALYs) with 95% uncertainty intervals (UI) using the Burden of Communicable Diseases in Europe software. Input data included TBE cases notified in 2017-2024 with residence and/or infection or exposure in Triveneto (autonomous provinces (AP) of Trento and Bolzano and regions of Veneto and Friuli-Venezia Giulia) and correction factors for TBE underdiagnosis and TBEV infection under-ascertainment.RESULTSIn 2017-2024, 295 TBE cases were notified in Triveneto. The mean annual burden of TBEV infections was estimated at 0.58 (95% UI: 0.55-0.62) DALYs per 100,000 population. Estimates were highest in 2022 (1.07; 95% UI: 1.00-1.14 DALYs/100,000). The areas with the highest burden were Belluno province (4.17; 95% UI: 3.88-4.46 DALYs/100,000/year) and the AP of Trento (2.84; 95% UI: 2.65-3.05 DALYs/100,000/year). Males accounted for 67.0% of DALYs. All age groups experienced on average ≤ 1 DALYs per 100,000 population per year.CONCLUSIONThe burden of TBEV infections in north-east Italy is relatively low and with an uneven geographical distribution. Increasing TBE vaccination coverage across age groups, prioritising elevated impact areas, may reduce the burden of TBEV infections in north-east Italy and maintain TBE as a low-burden disease.

PMID:42141861 | DOI:10.2807/1560-7917.ES.2026.31.17.2500733

Categories
Nevin Manimala Statistics

Associations of Job Strain and Health: Differences Among Nurses and Personal Support Workers in Residential Care Homes During the COVID-19 Pandemic

Workplace Health Saf. 2026 May 16:21650799261440222. doi: 10.1177/21650799261440222. Online ahead of print.

ABSTRACT

BACKGROUND: The COVID-19 pandemic revealed stressful working conditions experienced by health care workers in long-term care and seniors’ (LTCS) homes worldwide. However, differences in job strain among regulated and unregulated health care workers and its relationship to their health are understudied. This study examined associations between job strain-related working conditions and health changes, exploring differences between nurses and personal support workers (PSWs).

METHODS: This cross-sectional study used the Survey of Health Care Workers’ Experiences During the Pandemic (2021). Job strain-related working conditions included workload increases, working overtime, and beyond-role work. Outcomes were workers’ perceived changes in general health and mental health during the pandemic. Descriptive statistics and multivariable logistic regression models were employed, stratified by occupation, and controlled for covariates.

FINDINGS: Job strain prevalence during the pandemic was high, with more nurses reporting job strain-related working conditions (increased workloads, overtime, or beyond-role work) than PSWs. Associations between job strain working conditions and worsened health varied by occupation. Beyond-role work was associated with worsened mental health for both workers, but only worsened general health for nurses, not PSWs.

CONCLUSIONS: Differences among nurses and PSWs demonstrate the importance of understanding variations in roles, occupational experiences and policies regulating health care workers.

APPLICATION TO PRACTICE: These findings support the need for targeted monitoring of mental and general health among nurses and PSWs in LTCS settings. Occupational health practitioners can identify experiences of job strain among staff and provide counsel for solutions, collaborating with management to ensure the LTCS workforce’s health and safety.

PMID:42141859 | DOI:10.1177/21650799261440222

Categories
Nevin Manimala Statistics

Environmental scan and pedagogical evaluation of commercially available digital serious games for anatomy education

Anat Sci Educ. 2026 May 16. doi: 10.1002/ase.70257. Online ahead of print.

ABSTRACT

In medical and anatomy education, serious games (SGs) are increasingly recognized as promising pedagogical tools. Educators seeking to adopt SG may choose whether to build games or buy commercially available serious games (CASGs). However, exploration of the commercial market remains scarce as existing reviews focus on bibliographic databases. This study aimed to explore the commercial market for SG aimed at medical education and analyze the pedagogical underpinnings of SG for anatomy education. An environmental scan was conducted across five search areas targeting digital interactive games intended for healthcare professionals. Out of 4330 potential games identified, 1585 CASG for medical education were included after screening and eligibility assessment. Subsequently, 879 CASG for anatomy education were systematically evaluated against 15 pedagogical principles adapted from instructional and game design frameworks. Data extraction, scoring, and statistical analysis explored the presence of pedagogical principles and influencing factors. Findings show that the commercial market offers a range of CASG for medical education, primarily targeting knowledge acquisition in human anatomy for undergraduates. Most SG were quiz-based, designed for single player, and lacked affiliation with academic institutions. Systematic analysis of CASG for anatomy education shows few incorporations of pedagogical principles with in-game feedback and game rules being most common, while principles supporting engagement, adaptivity, and collaboration were scarce. In conclusion, while the commercial market offers SG for anatomy education, their educational potential remains constrained by limited pedagogical depth, which may limit their potential as pedagogical tools. These findings suggest opportunities to develop pedagogically robust games in anatomy education.

PMID:42141858 | DOI:10.1002/ase.70257

Categories
Nevin Manimala Statistics

Path With Art: Exploring the Impact of Community Arts Programming on Trauma Recovery

Health Promot Pract. 2026 May 16:15248399261445966. doi: 10.1177/15248399261445966. Online ahead of print.

ABSTRACT

This mixed-methods study explored the impact of community-based arts programming on psychosocial outcomes associated with trauma recovery among adults with low-to-no-income engaged in active recovery from homelessness, domestic abuse, substance use, and other forms of trauma. Conducted in partnership with Path with Art, the study assessed mental well-being, social connectedness, and self-efficacy using validated pre- and post-intervention surveys alongside qualitative exit-surveys. Participants (N = 80) demonstrated statistically significant improvements in mental well-being (p < .01), loneliness (p < .01), and self-efficacy (p = .02), following participation in 8-week community-based arts classes. Analysis of qualitative responses (N = 103) revealed five interconnected themes: social connection and community; mental and emotional well-being; personal growth and empowerment; motivation and purpose; and creative and educational engagement. Participants reported feeling less isolated, more confident and motivated, and described the arts as a meaningful tool for navigating challenges related to trauma recovery. The findings suggest community-based arts engagement supports psychosocial processes central to trauma recovery. While limitations such as self-selection bias and lack of a control group should be addressed in future research, the study contributes to growing evidence that arts programming can positively influence health outcomes in trauma-affected populations. These insights may inform public health strategies and community-based care models focused on recovery and resilience.

PMID:42141855 | DOI:10.1177/15248399261445966