Tag: nevin manimala

Environ Sci Pollut Res Int. 2024 May 24. doi: 10.1007/s11356-024-33753-5. Online ahead of print.

ABSTRACT

This theoretical investigation delves into the analysis of Reactive red 2 (RR-2) adsorption isotherms on metal hydroxide employing a sophisticated double-layer model characterized by dual-energy levels within the realm of physical adsorption phenomena. An examination of five distinct statistical physics frameworks was undertaken to elucidate the modeling and interpretation of equilibrium data. Expression for the physico-chemical parameters involved in the adsorption phenomena was derived based on statistical physics treatment. Fitting experimental adsorption isotherms (308-333 K) to a DAMTBS has revealed the number of anchored molecules per site, occupied receptor site density, and the number of adsorbed layers. The steric parameter n varies between 0.92 and 1.05. More importantly, it is evidenced that the adhesion mechanism of (RR-2) onto metal hydroxide as determined by the estimated adsorption energies (< 40 kJ/mol) supports a spontaneous and exothermic physisorption process. Thermodynamic potential functions such as entropy, Gibbs free energy, and internal energy have been computed based on the most suitable model. This research advances our physical understanding of how metal hydroxide captures dye molecules RR-2 through adsorption reaction for water depollution treatment.

PMID:38787473 | DOI:10.1007/s11356-024-33753-5

J Environ Qual. 2024 May 24. doi: 10.1002/jeq2.20570. Online ahead of print.

ABSTRACT

Dredged materials are often considered as candidates for replenishing lost topsoils in the watersheds of rivers and lakes. This study aimed to investigate the impacts of Lake Erie dredged material on the microbial community in a farm soil of Northwestern Ohio. Dredged material from the Toledo Harbor, OH was mixed with a local farm soil at ratios of 0:100, 10:90, 20:80, and 100:0 for soybean growth in a greenhouse for 123 days and was subject to 16S rRNA gene sequencing. α-Diversity analysis revealed that although the original dredged material hosted a highly diverse microbiome, soils blended with the dredged material had similar levels of bacterial diversity to 100% farm soil throughout the experiment. β-Diversity analysis demonstrated that, given the same plant status, that is, with or without soybean, blended soils had similar bacterial communities to 100% farm soil during the experiment. Furthermore, by the end of the experiment, all soils with soybeans merged into one cluster distinctive from those without the plants, indicating that the growth of plants played a dominating role in defining the structure of soil microbiomes. The majority (73.8%) of the operational taxonomy units that were unique to the original dredged material were not detected by the end of the experiment. This study demonstrates that up to 20% of the dredged material can be safely blended into the farm soil without distorting the microbial communities of the latter, implying a potential beneficial use of the dredged material for topsoil restoration.

PMID:38785161 | DOI:10.1002/jeq2.20570

Mol Med Rep. 2024 Jul;30(1):126. doi: 10.3892/mmr.2024.13249. Epub 2024 May 24.

ABSTRACT

Periodontal disease is a common infectious disease that can lead to the loss of teeth. Hower how to effectively suppress the inflammation with medication is unclear. The aim of the present study was to investigate the anti‑inflammatory effect of Oroxylin A in periodontitis and its potential role through heme oxygenase‑1 (HO‑1). Primary rat gingival fibroblasts (RGFs) were cultured using the tissue block method and identified by immunofluorescence. Following lipopolysaccharide (LPS) stimulation of RGFs, Oroxylin A was administered at 50, 100, 200 or 400 µg/ml. Reverse transcription‑quantitative PCR was used to assess mRNA expression of cyclooxygenase (COX)‑2, TNF‑α, RANKL and osteoprotegerin (OPG). Western blotting was used to detect protein expression levels of COX ‑2, TNF‑α, RANKL and OPG. Following HO‑1 knockdown, the same treatment was performed. The expression of COX‑2 in rat gingival tissue was observed by immunohistochemistry. One‑way analysis of variance and Student’s t test were used for statistical analysis. Oroxylin A downregulated mRNA expression of COX‑2, TNF‑α, RANKL and OPG in LPS‑induced RGFs. With increase of Oroxylin A dose, the expression of HO‑1 was gradually upregulated. When HO‑1 was knocked down, Oroxylin A did not downregulate the expression of COX‑2, TNF‑α, RANKL and OPG in LPS‑induced RGFs. Immunohistochemical results showed that expression of COX‑2 was downregulated by Oroxylin A, and the expression of TNF‑α, RANKL and OPG were also downregulated. Oroxylin A decreased expression of inflammatory cytokines in LPS‑induced RGFs and had a good inhibitory effect on periodontitis in rats.

PMID:38785151 | DOI:10.3892/mmr.2024.13249

J Appl Res Intellect Disabil. 2024 Jul;37(4):e13248. doi: 10.1111/jar.13248.

ABSTRACT

BACKGROUND: This study examines the extent of exposure to verbal violence experienced by people with intellectual disabilities and whether it differs based on their housing situation: living in the community, with family, or in a residential facility.

METHOD: One hundred and eighty-nine people with intellectual disabilities were interviewed about their experience with verbal violence.

RESULTS: Eighty-six percent reported experiencing verbal violence in their lifetime and approximately 77% experienced it the past week. Participants were most likely to be yelled at, and friends were the most common perpetrators. While there were few differences by setting, people living with their families were more likely to be laughed at and marginally more likely to experience rude comments.

CONCLUSIONS: Verbal violence is prevalent in the lives of people with intellectual disabilities in Israel. Interventions are necessary to assist people with intellectual disabilities to deal with such incidents, with possible additional supports needed for those living with family.

PMID:38785135 | DOI:10.1111/jar.13248

Plant Genome. 2024 May 24:e20459. doi: 10.1002/tpg2.20459. Online ahead of print.

NO ABSTRACT

PMID:38785130 | DOI:10.1002/tpg2.20459

Hum Vaccin Immunother. 2024 Dec 31;20(1):2357424. doi: 10.1080/21645515.2024.2357424. Epub 2024 May 24.

ABSTRACT

Solid cancer patients, compared to their healthy counterparts, are at a greater risk of contracting and suffering from severe complications and poorer prognosis after COVID-19 infections. They also have different immune responses after doses of COVID-19 vaccination, but limited evidence is available to reveal the effectiveness and help to guide immunization programs for this subpopulation; MEDLINE, Embase, Web of Science, Cochrane Library databases, and clinicaltrials.gov were used to search literature. The pooled seroconversion rate was calculated using a random-effects model and reported with a 95% confidence interval (CI); The review includes 66 studies containing serological responses after COVID-19 vaccination in 13,050 solid cancer patients and 8550 healthy controls. The pooled seropositive rates after the first dose in patients with solid cancer and healthy controls are 55.2% (95% CI 45.9%-64.5% N = 18) and 90.2% (95% CI 80.9%-96.6% N = 13), respectively. The seropositive rates after the second dose in patients with solid cancer and healthy controls are 87.6% (95% CI 84.1%-90.7% N = 50) and 98.9% (95% CI 97.6%-99.7% N = 35), respectively. The seropositive rates after the third dose in patients with solid cancer and healthy controls are 91.4% (95% CI 85.4%-95.9% N = 21) and 99.8% (95% CI 98.1%-100.0% N = 4), respectively. Subgroup analysis finds that study sample size, timing of antibody testing, and vaccine type have influence on the results; Seroconversion rates after COVID-19 vaccination are significantly lower in patients with solid malignancies, especially after the first dose, then shrinking gradually after the following two vaccinations, indicating that subsequent doses or a booster dose should be considered for the effectiveness of this subpopulation.

PMID:38785118 | DOI:10.1080/21645515.2024.2357424

Scand J Work Environ Health. 2024 May 23:4166. doi: 10.5271/sjweh.4166. Online ahead of print.

ABSTRACT

OBJECTIVES: This study aimed to quantify the duration of work participation and reasons for working years lost, according to gender and educational attainment, among a Norwegian population.

METHODS: Register data on labor market attachment between 2000-2015 were obtained from Statistics Norway. We included five cohorts: individuals turning 20 (N=323 333), 30 (N=386 006), 40 (N=388 962), 50 (N=358 745), and 60 years (N=284 425) between 1 January 2000 and 31 December 2005. Individuals were followed for ten years. Data completeness allowed calculation of the average time spent in work and years lost to health-related absences and non-employment states per cohort. Changes in state probabilities over time were also depicted. Mean differences between genders and educational levels, and corresponding 95% confidence intervals were based on 1000 bootstrap samples.

RESULTS: Both genders spent most time in work; however, per cohort, women worked approximately one year less than men. As cohorts aged, main reasons for working years lost changed from education and economic inactivity to sickness absence and disability pensioning; this trend was stronger for women than men. Individuals with a low education spent fewer years in work and more years in sickness absence and disability pensioning than highly educated peers. This difference tended to be larger for women and older cohorts.

CONCLUSIONS: Per cohort, women participated one year less in work than men and, depending on age, spent more time in education, economic inactivity, sickness absence, and disability pensioning. Stronger educational gradients were seen for work and health-related absences for older cohorts and women.

PMID:38785113 | DOI:10.5271/sjweh.4166

Behav Sleep Med. 2024 May 24:1-16. doi: 10.1080/15402002.2024.2355476. Online ahead of print.

ABSTRACT

OBJECTIVES: Perfectionism is an important factor in insomnia development and maintenance. Previous studies exploring the relationship between perfectionism and insomnia have predominantly relied on self-reported sleep measures. Therefore, this study sought to assess whether actigraphy-measured sleep parameters were associated with perfectionism.

METHODS: Sixty adults (85% females, mean age 30.18 ± 11.01 years) were sampled from the Australian general population. Actigraphy-derived objective sleep measures, subjective sleep diary measures, the Frost Multidimensional Perfectionism Scale (FMPS), Hewitt-Flett Multidimensional Perfectionism Scale (HFMPS) and Depression, Anxiety and Stress Scale 21 (DASS-21) were collected.

RESULTS: High perfectionism levels were associated with poor sleep, but these relationships differed between objective and subjective measures. Perfectionism via FMPS total score and subscales of Concern over Mistakes, Doubts about Actions, Personal Standards and Self-oriented Perfectionism correlated with subjective sleep onset latency and sleep efficiency with moderate effects (r = .26 to .88). In contrast, perfectionism via HFMPS total score and subscales of Socially Prescribed Perfectionism and Parental Expectations predicted objective sleep onset latency and sleep efficiency. Additionally, stress mediated the relationships between objective sleep efficiency and Concern over Mistakes and Doubts about Actions.

CONCLUSIONS: Perfectionism demonstrated stronger associations with subjective than objective sleep measures. Higher Parental Expectations and Socially Prescribed Perfectionism may increase one’s vulnerability to objectively measured poor sleep. Therefore, perfectionism may be important in preventing and treating insomnia.

PMID:38785108 | DOI:10.1080/15402002.2024.2355476

Cranio. 2024 May 24:1-5. doi: 10.1080/08869634.2024.2355856. Online ahead of print.

ABSTRACT

OBJECTIVE: This study aimed to evaluate the relationship between the presence of calcium deposits (CDs) around the dens axis and patients’ age, gender, and systemic diseases.

METHODS: This retrospective study was carried out by examining CBCT. Basic descriptive statistical analyses and normality tests were performed on all variables. The assumption of normality was checked using the Shapiro-Wilk method. The statistical significance level was accepted as a p-value less than 0.05.

RESULTS: CDs were observed in a total of 99 (21.9%) individuals. The incidence of CDs statistically significantly increased with age (p < .01),while it didn’t statistically significantly differ between genders (p = .47). 13% were systemically healthy, while 55% had hypertension. The incidence of CDs was statistically significantly higher in individuals with hypertension.

CONCLUSIONS: In the presence of CDs, the patient should be referred to a medical doctor to confirm the diagnosis of CDS and prevent possible complications.

PMID:38785099 | DOI:10.1080/08869634.2024.2355856

Scand J Work Environ Health. 2024 May 23:4167. doi: 10.5271/sjweh.4167. Online ahead of print.

ABSTRACT

OBJECTIVES: Several studies have found higher sickness absence in shared and open workspaces than in private offices, but little is known about why these differences occur. We propose and test job control as a potential mechanism underlying observed differences in the risk of physician-certified sickness absence between private offices and shared and open workspaces.

METHODS: We conducted a counterfactual mediation analysis using observational survey data from a nationally representative sample of Norwegian employees merged with prospective data from national registries (N=5512). The registry data included information about whether participants had any physician-certified sickness absence the year following the survey. Models were adjusted for age, sex, education level, occupation group, executive/leadership responsibility, and time spent on office work.

RESULTS: We found significantly higher sickness absence risk in conventional [risk ratio (RR) 1.12, 95% confidence interval (CI) 1.01‒1.25] and non-territorial (RR 1.20, 95% 1.04‒1.37) open-plan and non-territorial shared-room offices (RR 1.29, 95% CI 1.13‒1.48) compared to private offices. Natural indirect effects due to job control were statistically significant in all contrasts and accounted for 19-34% of total effects depending on contrast.

CONCLUSIONS: Findings were in line with hypothesized relationships and suggest that job control may be a mechanism underlying observed differences in sickness absence across office concepts. Future studies should continue to explore potential mechanisms linking shared and open workspaces to higher sickness absence and other unfavorable outcomes in the workplace, particularly with study designs that provide stronger basis for causal inference.

PMID:38785098 | DOI:10.5271/sjweh.4167