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Nevin Manimala Statistics

Therapeutic effect of Huoxue prescription combined with extracorporeal shock wave on rotator cuff injury

Zhongguo Gu Shang. 2025 Mar 25;38(3):245-51. doi: 10.12200/j.issn.1003-0034.20240235.

ABSTRACT

OBJECTIVE: To explore early clinical efficacy and advantages of Huoxue Fang’s directional dialysis combined with extracorporeal shock wave in treating rotator cuff injury.

METHODS: A retrospective analysis was performed for 42 patients with rotator cuff injury admitted from September 2020 to December 2022, and they were divided into shock wave group and directed dialysis group according to different treatment methods. There were 20 patients in shock wave group, including 12 males and 8 females; aged from 47 to 68 years old with an average of (63.2±3.3) years old;the course of disease ranged from 2 to 6 weeks with an average of (3.1±1.4) weeks;10 patients with gradeⅠand 10 patients with gradeⅡaccording to Ellman classification;non-steroidal drugs and extracorporeal shock wave therapy were performed. There were 22 patients in directed dialysis group, including 16 males and 6 females;aged from 44 to 67 years old with an average of (61.0±2.3) years old;the course of disease ranged from 2 to 8 weeks with average of (3.3±1.3) weeks;12 patients with gradeⅠand 10 patients with gradeⅡaccording to Ellman classification;with Huoxue prescription directed transdrug therapy based on shock wave group. Visual analogue scale (VAS), University of California at Los Angeles (UCLA) and range of motion (ROM) were compared between two groups before treatment, 1 and 6 months after treatment;changes of tumor necrosis factor-α (TNF-α), interleukin-1 (IL-1) and interleukin-6 (IL-6) between two groups were detected and compared. The complications between two groups were compared.

RESULTS: All patients were followed up, shockwave group followed up for 6 to 8 months with an average of (7.1±1.9) months, 6 to 8 months with an average of (7.2±1.8) months in directed dialysis group, with no statistical significance between two groups (P>0.05). At 1 and 6 months after treatment, VAS in directed dialysis group were (3.85±0.99), (1.24±0.75), which were lower than that in shock wave group (4.91±0.89), (1.81±0.84) (P<0.05). UCLA scores in directed dialysis group (25.25±2.34), (32.71±2.33) were higher than those in shock wave group (21.67±3.38) °, (29.11±3.01) °(P<0.05). Forward bending (139.15±20.39) °, (150.14±20.55) °, external rotation (63.46±16.62) °, (73.35±13.82) °, internal rotation (46.99±2.93) °, (58.24±2.10) ° in directed dialysis group were better than those in shock wave group (130.61±22.27) °, (141.28±19.47) °, external rotation (57.36±17.53) °, (68.12±13.64) °, internal rotation (41.21±3.10) °, (49.16±3.21) ° (P<0.05). At 1 and 6 months after treatment, TNF-α, IL-1 and IL-6 in directed dialysis group were (2.12±0.49), (2.06±0.55), (0.69±0.26) μg·L-1;(1.27±0.25), (1.14±0.23), (0.37±0.11) μg·L-1, which were lower than those in shock wave group (2.87±0. 51), (2.67±0.48), (0.92±0.21) μg·L-1, (1.88 ± 0.26), (1.36±0.27), (0.45±0.09) μg·L-1(P<0.05). At the latest follow-up, 8 patients got excellent result, 10 good and 2 poor in shock wave group;10 patients excellent, 10 good, and 2 poor in directed dialysis group;there was no significant difference between two groups (P>0.05). There were no complications such as skin allergy, subcutaneous hemorrhage, ecchymosis, vascular and nerve injury occurred in both groups.

CONCLUSION: For the treatment of rotator cuff injury, Huoxue prescription combined with extracorporeal shock wave is effective, which could not only release the local adhesion tissue, improve local blood circulation, accelerate absorption of inflammatory exudate of the local soft tissue, and promote recovery of the diseased muscle bond and ligament. It could also effectively relieve shoulder pain, improve shoulder motion, restore shoulder function, improve patients’ quality of life.

PMID:40148085 | DOI:10.12200/j.issn.1003-0034.20240235

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Early curative effect of upper capsular reconstruction combined with biceps tendon transposition for the treatment of unrepairable rotator cuff tear by arthroscopy

Zhongguo Gu Shang. 2025 Mar 25;38(3):238-44. doi: 10.12200/j.issn.1003-0034.20230950.

ABSTRACT

OBJECTIVE: To explore early curative effect of upper joint capsule reconstruction combined with biceps tendon transposition in treating irreparable rotator cuff tears.

METHODS: From October 2019 to March 2021, 16 patients with irreparable rotator cuff tear were underwent arthroscopic autogenous semitendinosus tendon transplantation for upper articular capsule reconstruction combined with biceps tendon transposition, included 12 males and 4 females, aged from 53 to 72 years old with an average of (62.13±5.35) years old; 3 patients on the left side and 13 patients on the right side. All patients had preoperatively limited joint mobility, resting pain, and mobility pain, and had a history of failure to respond to conservative treatment for more than 8 months. The duration of preoperative symptoms ranged from 45 to 144 months with an average of (85.25±32.08) months. Visual analogue scale (VAS) of shoulder pain, University of California Los Angeles (UCLA) score, Constant-Murley score, active and passive motion of shoulder joint were compared before operation and 2 years after operation, complications were recorded.

RESULTS: All 16 patients were followed up for 21 to 32 months with an average of (24.25±3.57) months. There were no complications such as incision infection, vascular and nerve injury, retear occurred. VAS, UCLA and Constant-Murley scores were improved from (5.75±1.18), (11.88±3.38) and (33.38±9.34) before operation to (1.13±0.89), (32.56±2.71), (89.06±6.25) at 2 years after operation (P<0.05). Anterior flexion, abduction, lateral external rotation and lateral internal rotation of shoulder joint were improved from (79.75±21.36) °, (62.06±10.49) °, (19.19±5.41) °, (3.04±0.21) °, respectively to (156.94±13.18) °, (116.19±12.59) °, (42.63±6.07) °, (8.16±0.64) ° at 2 years after operation. Anterior flexion, abduction, lateral lateral rotation and lateral internal rotation of shoulder joint were improved from (116.28±21.47) °, (107.12±9.67) °, (27.62±4.70) °, (4.21±0.41) °, respectively to (165.28±7.15) °, (153.34±4.69) °, (52.46±4.46) °, (9.68±0.68) ° at 2 years after operation, and the difference was statistically significant (P<0.05).

CONCLUSION: Arthroscopic autograft of semitendinosus tendon combined with transposition of biceps tendon could achieve satisfactory early clinical results in treating patients with irreparable rotator cuff tear, which is a reliable and effective surgical method.

PMID:40148084 | DOI:10.12200/j.issn.1003-0034.20230950

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Comparative study of the treatment of scapular fractures by posterior axillary and lateral scapular approaches

Zhongguo Gu Shang. 2025 Mar 25;38(3):231-7. doi: 10.12200/j.issn.1003-0034.20240719.

ABSTRACT

OBJECTIVE: To compare clinical efficacy of transaxillary posterior margin approach and translateral margin approach for the treatment of Miller typeⅡand Ⅳ scapular fractures.

METHODS: From June 2020 to June 2024, 28 patients with fresh scapular fractures (Miller typeⅡand Ⅳ) who were treated with open reduction and locked plate internal fixation were retrospectively analyzed and divided into two groups. There were 13 patients in posterior axillary margin group, including 8 males and 5 females, aged from 26 to 71 years old with an average of (39.2±6.5) years old;5 patients with typeⅡand 8 patients with type Ⅳ according to Miller classification;9 patients caused by falling down, 4 patients caused by car accident;7 patients on the right side, 6 patients on the left side;the time from injury to operation ranged from 3 to 5 days with an average of (4.07±0.86) days. There were 15 patients in lateral scapula margin group, including 10 males and 5 females, aged from 27 to 63 years old with an average of (43.6±8.5) years old;7 patients with typeⅡand 8 patients with type Ⅳ according to Miller classification;10 patients caused by falling down, 5 patients caused by car accident;6 patients on the right side, 9 patients on the left side;the time from injury to operation ranged from 3 to 5 days with an average of (4.20±0.67) days. Operative time, intraoperative blood loss, fracture healing time, glenopolar angle (GPA) immediately after operation were compared between two groups. Visual analogue scale (VAS) and Constant-Murley shoulder joint function score were used to evaluate clinical effect at 3 and 6 months after operation, respectively, and the joint motions were evaluated at 6 months after operation.

RESULTS: None of patients occurred wound infection, vascular and nerve damage, loosening or rupture of internal fixation. Both groups were followed up for 8 to 12 months with an average of (9.6±1.5) months. Operative time and intraoperative blood loss of posterior axillary margin group were (76.92±5.60) min and (84.86±10.08) ml, respectively, which were better than those of lateral scapula margin group(84.67±6.93) min and(115.00±12.39) ml(P<0.05). Immediate GPA in posterior axillary margin group (36.62±0.87) °and lateral scapula margin group (36.20±0.82)°were significantly improved compared with preoperative (16.10±1.14) °, (16.20±1.20) °(P<0.05), while there was no statistical significance between two groups (P>0.05). There were no significant difference in fracture healing time and postoperative VAS at 3 and 6 months between two groups (P>0.05). Postoperative Constant-Murley score of posterior axillary margin group (75.00±4.02) was higher than that of lateral scapular margin group (70.86±4.24) at 3 months (P<0.05), while there was no significant difference between two groups at 6 months after operation (P>0.05). At 6 months after operation, joint motion of posterior axillary margin group in flexion (160.38±13.61)°, abduction (154.61±13.91)°, rotation (83.08±2.53)°, rotation (62.69±2.59) ° and extension (51.54±3.15) °, respectively, which were higher than that of lateral scapular margin group in (148.00±15.44)°, (144.00±11.05)°, (79.67±3.99)°, (57.33±4.95)°, (47.33±4.16)°(P<0.05).

CONCLUSION: Compared with lateral margin of scapula intermuscular space approach, Buttress approach through the posterior axillary margin for the treatment of Miller typeⅡand Ⅳ scapular fractures provides extensive intraoperative visual field exposure, stable fracture support and less surgical trauma, which could shorten operative time and reduce intraoperative blood loss, providing a new reference for the treatment of complex scapular fractures.

PMID:40148083 | DOI:10.12200/j.issn.1003-0034.20240719

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A case-control study of shoulder arthroscopic double row and single row technique for the treatment of Ideberg type ⅠA scapular glenoid fracture

Zhongguo Gu Shang. 2025 Mar 25;38(3):223-30. doi: 10.12200/j.issn.1003-0034.20240947.

ABSTRACT

OBJECTIVE: To compare clinical effect of arthroscopic double row fixation and single row fixation in treating Ideberg typeⅠA scapular glenoid fracture.

METHODS: From June 2018 to December 2022, 26 patients with Ideberg typeⅠA scapular glenoid fracture treated with shoulder arthroscopy were divided into single-row anchor group and double-row anchor group according to the fixation method of fracture block. There were 12 patients in single-row anchor group, including 7 males and 5 females, aged from 25 to 53 years old with an average of (38.42±9.61) years old;the time from injury to operation ranged from 2 to 7 days with an average of (4.75±1.82) days. There were 14 patients in double-row anchor group, including 10 males and 4 females, aged from 21to 53 years old with an average of (37.36±10.19) years old;the time from injury to operation ranged from 1 to 8 days with an average of (4.21±2.01) days. The changes of shoulder joint flexion, abduction, lateral lateral rotation, Constant-Murley shoulder function score and Rowe scores were compared between two groups before operation and 1 year after operation. The percentage of bone mass in pelvis area before operation and the percentage of bone defect in pelvis area at the latest follow-up were compared between two groups.

RESULTS: All patients were followed up for 12 to 15 months with an average of (13.08±1.17) months in single-row anchor group and 12 to 15 months with an average of (13.29±1.07) months in double-row anchor group, with no statistical significance between two groups (P>0.05). The results of anterior flexion, abduction and lateral lateral rotation in single-row anchor group were(86.67±6.62) °, (79.50±5.68) °, (38.17±1.70) ° before operation, and (162.50±4.52)°, (169.17±3.35)°, (50.67±10.20)° at 1 year after operation; while in double-row anchor group were (84.14±5.48) °, (81.71±5.20) °, (39.29±3.63) ° before operation and (162.29 ± 5.53) °, (167.14±3.61) °, (56.93±9.56) ° at 1 year after operation;the difference between two groups before operation and 1 year after operation was statistically significant (P<0.05). There were no significant difference between two groups (P>0.05). Constant-Murley scores and Rowe scores in single-row anchor group were (55.42±3.75), (43.75±18.49) before operation and (94.83±2.21), (95.42±4.50) at 1 year after operation, respectively;while in double-row anchor group were (54.50±7.88), (41.79±18.25) before operation and (94.36±4.73), (95.00±4.80) at 1 year after operation;there was no significant difference in Constant-Murley score and Rowe score between two groups before operation and 1 year after operation (P>0.05). There was significant difference in the percentage of bone mass in pelvis area between two groups before operation (P>0.05). There was no significant difference in the percentage of bone defect in the shoulder area between single-row anchor group(4.42±1.51)% and double-row anchor group (2.71±1.44)% at 1 year after operation (P<0.05).

CONCLUSION: Both single and double row fixation techniques for the treatment of Ideberg typeⅠA scapular glenoid fracture could receive satisfactory functional recovery. However, double-row fixation has more advantages in reducing bone resorption of fracture mass.

PMID:40148082 | DOI:10.12200/j.issn.1003-0034.20240947

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Assessing courtesy reporting bias in facility-based surveys on person-centred maternity care: evidence from urban informal settlements in Nairobi and Lusaka

J Glob Health. 2025 Mar 28;15:04090. doi: 10.7189/jogh.15.04090.

ABSTRACT

BACKGROUND: Experience of care is typically measured through client exit surveys administered in the facility. Evidence suggests that such measures suffer from courtesy reporting bias whereby respondents do not accurately report on their experiences while in the facility. We explored the presence of courtesy bias by comparing women’s reported experience of person-centred maternity care (PCMC) from facility-based client exit surveys to mobile phone-based surveys out of the facility in Nairobi and Lusaka’s urban informal settlements.

METHODS: We randomly and independently sampled women in the facilities for either a facility-based survey (n = 233 in Lusaka and n = 112 in Nairobi) or a mobile phone-based survey (n = 203 in Lusaka and n = 300 in Nairobi) within one to two weeks of facility discharge. The questionnaire included a validated PCMC scale. After adjusting for differences in women’s characteristics across groups, we compared PCMC scores between facility and phone-based samples. We ran multilevel linear regression models to assess PCMC by survey modality in each city.

RESULTS: In both cities, over 70.0% of women were aged 20-34 years and were married, at least two thirds had secondary education, and over 95.0% were unaccompanied during labour/delivery. The overall PCMC score was 69.3% among women surveyed on the phone compared to 70.2% among those surveyed in the facility in Nairobi. In Lusaka, it was 57.5% on the phone compared to 56.8% in-facility. We found no statistically significant differences in PCMC scores between survey modalities in both cities, after adjusting for differences in women’s characteristics.

CONCLUSIONS: We did not detect significant courtesy reporting bias in PCMC in facility-based client exit surveys in the context of urban informal settlements in Nairobi and Lusaka. Experience of PCMC can be measured through in-facility client exit surveys or mobile phone surveys. However, it is critical to address challenges related to a mobile phone-based approach.

PMID:40147000 | DOI:10.7189/jogh.15.04090

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An ensemble approach improves the prediction of the COVID-19 pandemic in South Korea

J Glob Health. 2025 Mar 28;15:04079. doi: 10.7189/jogh.15.04079.

ABSTRACT

BACKGROUND: Modelling can contribute to disease prevention and control strategies. Accurate predictions of future cases and mortality rates were essential for establishing appropriate policies during the COVID-19 pandemic. However, no single model yielded definite conclusions, with each having specific strengths and weaknesses. Here we propose an ensemble learning approach which can offset the limitations of each model and improve prediction performances.

METHODS: We generated predictions for the transmission and impact of COVID-19 in South Korea using seven individual models, including mathematical, statistical, and machine learning approaches. We integrated these predictions using three ensemble methods: stacking, average, and weighted average ensemble (WAE). We used train and test errors to measure a model’s performance and selected the best covariate combinations based on the lowest train error. We then evaluated model performance using five error measures (r2, weighted mean absolute percentage error (WMAPE), autoregressive integrated moving average (ARIMA), mean squared error (MSE), root mean squared error (RMSE), and mean absolute percentage error (MAPE)) and selected the optimal covariate combination accordingly. To validate the generalisability of our approach, we applied the same modelling framework to USA data.

RESULTS: Booster shot rate + Omicron variant BA.5 rate was the most commonly selected combination of covariates. For raw data evaluated using the WMAPE, individual models achieved the following: Generalised additive modelling (GAM) reached a value of 0.244 for the daily number of confirmed cases, a value of 0.172 for the time series Poisson for the daily number of confirmed deaths, and a value of 0.022 for both ARIMA and time series Poisson for the daily number of ICU patients. For smoothed data, the Holt-Winters model achieved a value of 0.058 for daily confirmed cases, while ARIMA attained a value of 0.058 for the daily number of confirmed deaths and 0.013 for the daily number of ICU patients. Among ensemble models, the SVM-based stacking ensemble achieved error values of 0.235 for the daily number of confirmed cases, 0.118 for the daily number of deaths, and 0.019 for the daily number of ICU patients on raw data. For smoothed data, the average ensemble and weighted average ensemble achieved 0.060 for the daily number of confirmed cases and 0.013 for daily ICU patients. The ensemble models also generalised well when applied to data from the USA.Booster shot rate + Omicron variant BA.5 rate was the most commonly selected combination of covariates. For raw data, GAM (0.244) predicted daily confirmed cases best, time series Poisson (0.172) predicted daily confirmed deaths, and both ARIMA and time series Poisson (0.022) predicted daily ICU patients, based on WMAPE. For smoothed data, time series Poisson predicted daily confirmed cases (0.065) best, while ARIMA best predicted daily confirmed deaths (0.058) and ICU patients (0.013). For ensemble models, stacking ensemble using SVM was the best model for predicting daily confirmed cases (0.228), deaths (0.11), and ICU patients (0.02). With smoothed data, average ensemble and WAE were the best models for predicting daily confirmed cases (0.058) and ICU patients (0.011). The performance of ensemble models was generalised to other countries using the USA data for predictive performance.

CONCLUSIONS: No single model performed consistently. While the ensemble models did not always provide the best predictions, a comparison of first-best and second-best models showed that they performed considerably better than the single models. If an ensemble model was not the best performing model, its performance was always not far from the best single model: a look at the mean and variance of the error measures shows that ensemble models provided stable predictions without much variation in their performances compared to single models. These results can be used to inform policymaking during future pandemics.

PMID:40146993 | DOI:10.7189/jogh.15.04079

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Stress and Hypertension Among African American Female Family Caregivers of Persons Living With Alzheimer Disease and Related Dementias: Protocol for a Pilot Internet-Based Randomized Controlled Trial

JMIR Res Protoc. 2025 Mar 27;14:e66975. doi: 10.2196/66975.

ABSTRACT

BACKGROUND: Caregivers of persons with Alzheimer disease and related dementias (ADRD) neglect their health, including by ignoring stress levels. African American women are vulnerable and susceptible to hypertension. Chronic caregiving stress and hypertension place them at high risk for cardiovascular disease. Addressing stress reactivity or resilience is vital in lessening their caregiving stress, enhancing their quality of life (QOL), and fostering healthy blood pressure (BP) self-care behaviors.

OBJECTIVE: This pilot study aims to investigate the feasibility and acceptability of implementing the Mindfulness in Motion (MIM) plus the Dietary Approaches to Stop Hypertension (DASH) intervention in this population and to evaluate its effect on ADRD caregivers’ stress and QOL. Additionally, it explores the mediation of stress reactivity or resilience between interventions and self-care behaviors.

METHODS: A small randomized controlled trial pilot study will recruit 28 African American or Black female caregivers aged 40 years diagnosed with hypertension and on an antihypertensive medication. Participants will be randomly assigned to either the MIM DASH or the Alzheimer’s Association caregiver training group (attention control). Trained facilitators will deliver both interventions over 8 weeks through 1-hour, group, internet-based sessions, via video or telephone. After completion, both groups will receive coaching calls over 9 months, beginning with 8 weekly calls followed by 4 monthly calls to encourage use of the educational materials. Primary outcome measures include feasibility (recruitment and retention) and acceptability (attendance). Secondary measures assess caregiver stress (Perceived Stress Scale), QOL, and self-care behaviors (Food Frequency Questionnaire and self-reported physical activity). Data collection occurs at baseline, 3 months, and 9 months. Quantitative data will be analyzed using descriptive statistics, CIs, and mediation models.

RESULTS: This study was approved by the institutional review board in April 2022 and funded in May 2022. The first data were collected in January 2023, and the last data were collected in September 2024. The completion of all aims’ data analysis is anticipated in spring 2025. The participants’ mean age was 62.4 (SD 7.98) years, with a mean baseline systolic BP of 128 (SD 19) mm Hg and diastolic BP of 79 (SD 10) mm Hg. Participants reported that MIM DASH was acceptable (at a mean score of 59.08, SD 7.38, compared to 60.83, SD 5.56 for caregiver training). Regarding feasibility, as reflected in attendance, MIM DASH participants had a mean attendance of 6.3 (SD 2.3) sessions, and the caregiver training group had 4.9 (SD 2.9) sessions.

CONCLUSIONS: This study’s findings demonstrate the feasibility of conducting an internet-based intervention (MIM DASH) for African American women with hypertension who also care for families living with ADRD. These results will inform the design of a larger randomized controlled trial to evaluate the intervention’s efficacy and scalability further.

TRIAL REGISTRATION: ClinicalTrials.gov NCT05721482; https://clinicaltrials.gov/study/NCT05721482.

INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/66975.

PMID:40146982 | DOI:10.2196/66975

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Analytical solution of MHD bioconvection Williamson nanofluid flow over an exponentially stretching sheet with the impact of viscous dissipation and gyrotactic microorganism

PLoS One. 2025 Mar 27;20(3):e0306358. doi: 10.1371/journal.pone.0306358. eCollection 2025.

ABSTRACT

Nanofluids achieve high thermal transport efficiency by uniformly dispersing small particles in base liquids, significantly enhancing the heat transfer coefficients and making them vital in various thermal engineering applications. The research examines non-uniform thermal conductivity and activation energy critical for accurately describing fluid behaviour. The study incorporates bioconvection to prevent nanoparticle settling and ensure fluid stability through motile microorganisms. The governing partial differential equations are converted into ordinary differential equations that are solved using the Homotopy Analysis Method (HAM), to provide a strong mathematical framework for the analysis. This study finds that the velocity of the fluid decreases with magnetic constraint intensification and time retardation. however, heat transfer increases at higher radiation, and heat absorption/emission parameters but decreases with a higher Prandtl number, while an increased Schmidt number leads to decreased concentration profiles. This paper investigates a nano-Williamson fluid (NWF) flow over an exponentially stretched surface in a permeable medium, considering essential variables such as mixed convection, electromagnetic forces, non-linear thermal radiation, heat production, Joule heating and ohmic dissipation that are essential for understanding its complicated behavior.

PMID:40146967 | DOI:10.1371/journal.pone.0306358

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Evaluating the Usability, Acceptability, User Experience, and Design of an Interactive Responsive Platform to Improve Perinatal Nurses’ Stigmatizing Attitudes Toward Substance Use In Pregnancy

JMIR Hum Factors. 2025 Mar 27. doi: 10.2196/67685. Online ahead of print.

ABSTRACT

BACKGROUND: Perinatal nurses are increasingly encountering patients who have engaged in perinatal substance use (PSU). Despite growing evidence demonstrating the need to reduce nurses’ stigmatizing attitudes toward PSU, limited interventions are available to target these attitudes and support behavior change – especially those that reflect the overwhelming evidence that education alone is insufficient to change practice behavior. Arts-based interventions are associated with increasing nursing empathy, changing patient attitudes, improving reflective practice, and decreasing stigma. We adapted ArtSpective™ for PSU, a previously evaluated arts-based intervention to reduce stigma among perinatal nurses, into an interactive digital responsive platform that facilitates intervention delivery asynchronously.

OBJECTIVE: This study aimed to evaluate the usability, acceptability, and feasibility of the interactive, responsive platform version of ArtSpective™ for PSU, designed to deliver an adapted version of the in-person intervention to improve nurses’ stigmatizing attitudes toward PSU, following a mixed methods approach. Our goal was to elicit user experience strengths and weaknesses related to the design of the responsive platform and identify strategies to overcome them.

METHODS: This study used a mixed-methods approach to explore the platform’s usability and user experience and its acceptability as an intervention to address stigma and implicit bias related to PSU. Theatre testing was used to qualitatively assess usability and acceptability perspectives with nurses and experts, as well as a modified version of the previously validated 8-item Abbreviated Acceptability Rating Profile for quantitative assessment. Analyses of quantitative data regarding acceptability and satisfaction were performed using descriptive statistics (mean, standard deviation, frequency, percentage). All qualitative data were analyzed iteratively using an inductive framework analysis approach.

RESULTS: A total of 21 nurses and four experts in stigma, implicit bias, and instructional design completed theatre-testing sessions. The mean duration of interviews for nurses was 31.92 (SD 11.32) minutes, and for experts, 40.73 (SD 8.57) minutes. All participants indicated that they found the digital adaptation of the intervention to be highly acceptable, with mean acceptability items ranging from 5.0 (SD 1.0) to 5.5 (SD 0.6) on a 1-6 agreement scale. Nurses reported high satisfaction with the platform on a 1-6 agreement scale, with mean satisfaction items ranging from 5.14 (SD 0.56) to 5.29 (SD 0.63) on a 1-6 agreement scale. 1,797 interview segments were coded from the theatre-testing sessions with four major themes: appearance, navigation, characterization, and overall platform, and 16 subthemes were identified. Consistent with the quantitative findings, the results were positive overall, with participants expressing high satisfaction related to the platform’s appearance, ease with which they could navigate the various modules, engagement, clarity of the presentation, and feasibility to be completed asynchronously.

CONCLUSIONS: Developing and evaluating the usability of a digital adaptation of ArtSpective™ for PSU resulted in strong support for the usability, acceptability, and satisfaction of the program and provided insight into key aspects related to acceptability and usability that should be considered when designing a digital adaptation of an arts-based intervention for healthcare providers.

PMID:40146964 | DOI:10.2196/67685

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Identifying multiple sclerosis in linked administrative health data in Aotearoa New Zealand

N Z Med J. 2025 Mar 28;138(1612):71-82. doi: 10.26635/6965.6823.

ABSTRACT

AIM: The 2006 New Zealand national multiple sclerosis (MS) prevalence study (NZMSPS) provided invaluable information about the prevalence of MS in Aotearoa and characteristics of people with this debilitating condition. This study aimed to update the NZMSPS by identifying people with MS using linked administrative health records.

METHODS: Cases of MS were identified from hospitalisation, pharmaceutical dispensing, needs assessments for older adults and disability support records between January 1988 and June 2022. MS prevalence was estimated, and characteristics described and compared by sub-groups.

RESULTS: A total of 7,890 people (73% female) with MS were identified across the study period. The estimated crude national prevalence of MS in 2022 was 96.6 per 100,000 (72.4 in 2006). MS prevalence exhibited a strong latitudinal gradient. Estimated age-adjusted prevalence was highest for Europeans (124.7 per 100,000), followed by Middle Eastern/Latin American/African (MELAA) (85.5), Māori (41.8), Asian (16.8) and Pacific peoples (11.1) ethnic groups.

CONCLUSION: Characteristics of MS cases were broadly similar to previous research, excepting a greater estimated prevalence among Māori, and a lower relative estimated prevalence for Auckland than surrounding regions. Linked administrative health data can be used to identify people with MS in Aotearoa, providing a mechanism for further research.

PMID:40146958 | DOI:10.26635/6965.6823