Tag: nevin manimala

MDM Policy Pract. 2023 Mar 27;8(1):23814683231163190. doi: 10.1177/23814683231163190. eCollection 2023 Jan-Jun.

ABSTRACT

Background. Personal autonomy in lung cancer screening is advocated internationally, but health systems diverge in their approach, mandating either shared decision making (with a health care professional) or individual decision making. Studies of other cancer screening programs have found that individual preferences for the level of involvement in screening decisions vary across different sociodemographic groups and that aligning approaches with individual preferences has the potential to improve uptake. Method. For the first time, we examined preferences for decision control among a cohort of UK-based high-risk lung cancer screening candidates (N = 727). We used descriptive statistics to report the distribution of preferences and chi-square tests to examine associations between decision preferences and sociodemographic variables. Results. Most (69.7%) preferred to be involved in the decision with varying degrees of input from a health care professional. Few (10.2%) wanted to make the decision alone. Preferences were also associated with educational attainment. Conclusion. These findings suggest one-size-fits-all approaches may be inadequate in meeting diverse preferences, particularly those placing sole onus on the individual.

HIGHLIGHTS: Preferences for involvement in decision making about lung cancer screening are heterogeneous among high-risk individuals in the United Kingdom and vary by educational attainment.Further work is needed to understand how policy makers might implement hybrid approaches to accommodate individual preferences and optimize lung cancer screening program outcomes.

PMID:37009636 | PMC:PMC10064161 | DOI:10.1177/23814683231163190

Int J Paramed. 2023 Jan-Mar;1(1):73-84. doi: 10.56068/ampo6844. Epub 2023 Jan 9.

ABSTRACT

BACKGROUND: Anticipating an increased utilization of healthcare facilities during the COVID-19 surge, the San Francisco Department of Public Health developed a plan to deploy neighborhood-based Field Care Clinics (FCCs) that would decompress emergency departments by serving patients with low acuity complaints. These clinics would receive patients directly from the Emergency Medical Services (EMS) system. Transports were initiated by a paramedic-driven protocol, originally by EMS crews and later by the Centralized Ambulance Destination Determination (CADDiE) System. In this study, we evaluated the outcomes of EMS patients who were transported to the FCC, specifically as to whether they required subsequent transfer to the emergency department.

METHODS: We performed a retrospective study of all patients transported to the Bayview-Hunters Point (BHP) neighborhood FCC by EMS between April 11^th, 2020, and December 16^th, 2020. Descriptive statistics and Chi-Square Tests were used to analyze patient data.

RESULTS: In total, 35 patients (20 men, 15 women, average age of 50.9 years) were transported to the FCC. Of these, 16 were Black/African American, 7 were White, 3 were Asian, with 9 identifying as of other races and 9 of Hispanic ethnicity. Twenty-three of these transports resulted from a CADDiE recommendation. Approximately half (n=20) of calls originated within the BHP neighborhood. The most frequent patient complaint was “Pain.” Of patients transported to the FCC, 23 were treated and discharged. The 12 remaining patients required hospital transfer, with 3 being discharged after receiving treatment in the emergency department and 9 requiring hospital admission, psychiatric, or sobering services. The likelihood of hospital transfer did not significantly vary by sex (p=0.41), 9-1-1 call origination relative to BHP neighborhood (p=0.92), or CADDiE recommendation (p=0.51).

CONCLUSION: Three-fourths of patients who required subsequent hospital transfer were admitted or required specialized services, suggesting that the FCC was viable for managing low acuity conditions. However, the underutilization of the FCC by EMS as a transport destination and a high hospital transfer rate indicates training and protocol refinement opportunities. Despite the small cohort size, this study demonstrates that an FCC alternative care site can act as a viable source for urgent and emergency care during a pandemic.

PMID:37009632 | PMC:PMC10062198 | DOI:10.56068/ampo6844

Chaos Solitons Fractals. 2023 May;170:113395. doi: 10.1016/j.chaos.2023.113395. Epub 2023 Mar 27.

ABSTRACT

This paper presents a stochastic model for COVID-19 that takes into account factors such as incubation times, vaccine effectiveness, and quarantine periods in the spread of the virus in symptomatically contagious populations. The paper outlines the conditions necessary for the existence and uniqueness of a global solution for the stochastic model. Additionally, the paper employs nonlinear analysis to demonstrate some results on the ergodic aspect of the stochastic model. The model is also simulated and compared to deterministic dynamics. To validate and demonstrate the usefulness of the proposed system, the paper compares the results of the infected class with actual cases from Iraq, Bangladesh, and Croatia. Furthermore, the paper visualizes the impact of vaccination rates and transition rates on the dynamics of infected people in the infected class.

PMID:37009628 | PMC:PMC10040364 | DOI:10.1016/j.chaos.2023.113395

Front Surg. 2023 Mar 15;10:1120030. doi: 10.3389/fsurg.2023.1120030. eCollection 2023.

ABSTRACT

PURPOSE: This study sought to conduct several three-dimensional measurements of the distal ulna in healthy Han Chinese, providing the anatomical basis for the diagnosis and treatment of hand trauma, distal ulnar disorders, and the design of wrist prostheses.

METHODS: 50 Han Chinese men and women that underwent computed tomography (CT) scans of the distal ulnar carpus were included in the present study. A three-dimensional digital model of the distal ulna was reconstructed using Mimics software. Moreover, the anatomical data of 10 indicators were measured using MIMICS software. Each index data was measured by 2 investigators independently, and the average value was taken. The data were stratified and compared between left and right sides and men and women.

RESULTS: A 3D digital model of the distal ulnar bone with a realistic shape was reconstructed. The 10 anatomical parameters measured are as follows: The length of the ulnar styloid process (posterior anterior), The length of the ulnar styloid process(anterior and posterior); the transverse diameter of the ulnar head; the anteroposterior diameter of the ulnar head. The radial inclination angle of the ulna; the ulnar inclination angle; the distal space between the ulna and radius; the ulnar notch angle of the lower radius. The anterior and posterior diameters of the ulnar notch of the lower radius, and the superior and inferior diameters of the ulnar notch of the lower radius. Statistical analysis showed no significant difference after stratification by laterality and gender.

CONCLUSION: our findings can providing the anatomical basis for the diagnosis and treatment of hand trauma, distal ulnar disorders and further improve currently available wrist joint prostheses.

TYPE OF STUDY: Observational, Cross-sectional study, LOE: Level II.

PMID:37009615 | PMC:PMC10050329 | DOI:10.3389/fsurg.2023.1120030

Front Surg. 2023 Mar 15;10:1112473. doi: 10.3389/fsurg.2023.1112473. eCollection 2023.

ABSTRACT

OBJECTIVES: The inflammatory response caused by gastric cancer surgery and the low nutritional status of patients with gastric cancer can cause growth of tumour cells, reduce immunity, and increase tumour burden. We investigated the effects of different surgical methods on postoperative inflammatory response and nutritional status in patients with distal gastric cancer.

METHODS: Clinical data of 249 patients who underwent radical distal gastrectomy for distal gastric cancer from February 2014 to April 2017 were retrospectively analysed. Patients were divided according to the surgical method (open distal gastrectomy [ODG], laparoscopic-assisted distal gastrectomy [LADG] and total laparoscopic distal gastrectomy [TLDG]). Characteristics of different surgical procedures, including inflammation parameters and nutritional indicators, and different time points (preoperatively, 1 day postoperatively, and 1 week postoperatively) were compared using non-parametric test analysis.

RESULTS: At postoperative day 1, white blood cell count [WBC], neutrophil count [N], neutrophil/lymphocyte ratio [NLR], and platelet/lymphocyte ratio [PLR] increased in the three groups, and ΔN and ΔNLR were significant; the smallest change was observed in TLDG (P < 0.05). Albumin [A]and prognostic nutrition index [PNI] significantly decreased; the smallest ΔA and ΔPNI, which were statistically significant, were noted in TLDG. One week postoperatively, WBC, N, NLR, and PLR decreased, and WBC, N, and NLR showed significant difference. A and PNI of the three groups increased after 1 week, and A and PNI showed significant differences.

CONCLUSION: Postoperative inflammatory response and nutritional status of patients with distal gastric cancer are associated with the surgical technique. TLDG has little influence on the inflammatory response and nutritional level compared with LADG and ODG.

PMID:37009613 | PMC:PMC10050336 | DOI:10.3389/fsurg.2023.1112473

Front Surg. 2023 Mar 16;10:1130919. doi: 10.3389/fsurg.2023.1130919. eCollection 2023.

ABSTRACT

OBJECTIVE: Cardiopulmonary exercise testing (CPET) is currently recommended for all patients undergoing lung resection with either respiratory comorbidities or functional limitations. The main parameter evaluated is oxygen consumption at peak (VO₂peak). Patients with VO₂peak above 20 ml/kg/min are classified as low risk surgical candidates. The aims of this study were to evaluate postoperative outcomes of low-risk patients, and to compare their outcomes with those of patients without pulmonary impairment at respiratory function testing.

METHODS: Retrospective monocentric observational study was designed, evaluating outcomes of patients undergoing lung resection at San Paolo University Hospital, Milan, Italy, between January 2016 and November 2021, preoperatively assessed by CPET, according to 2009 ERS/ESTS guidelines. All low-risk patients undergoing any extent surgical lung resection for pulmonary nodules were enrolled. Postoperative major cardiopulmonary complications or death, occurring within 30 days from surgery, were assessed. A case-control study was nested, matching 1:1 for type of surgery the cohort population with control patients without functional respiratory impairment consecutively undergoing surgery at the same centre in the study period.

RESULTS: A total of 80 patients were enrolled: 40 subjects were preoperatively assessed by CPET and deemed at low risk, whereas 40 subjects represented the control group. Among the first, 4 patients (10%) developed major cardiopulmonary complications, and 1 patient (2.5%) died within 30 days from surgery. In the control group, 2 patients (5%) developed complications and none of the patients (0%) died. The differences in morbidity and mortality rates did not reach statistically significance. Instead, age, weight, BMI, smoking history, COPD incidence, surgical approach, FEV1, Tiffenau, DLCO and length of hospital stay resulted significantly different between the two groups. At a case-by-case analysis, CPET revealed a pathological pattern in each complicated patient, in spite of VO₂peak above target for safe surgery.

CONCLUSIONS: Postoperative outcomes of low-risk patients undergoing lung resections are comparable to those of patients without any pulmonary functional impairment; nonetheless the formers represent a dramatically different category of individuals from the latter and may harbour few patients with worse outcomes. CPET variables overall interpretation may add to the VO₂peak in identifying higher risk patients, even in this subgroup.

PMID:37009610 | PMC:PMC10062454 | DOI:10.3389/fsurg.2023.1130919

IJID Reg. 2023 Mar 1;7:77-83. doi: 10.1016/j.ijregi.2023.02.008. eCollection 2023 Jun.

ABSTRACT

OBJECTIVE: Carbapenemase-producing carbapenem-resistant Enterobacterales (CP-CRE) are usually healthcare associated. The aim of this study was to investigate the epidemiology of hospital-acquired CRE and multi-drug-resistant infections, and identify associated risk factors in hospitalized patients in Northeast Ethiopia.

METHODS: This cross-sectional study was conducted in patients admitted with sepsis between January and June 2021. Demographic and clinical data were collected using questionnaires. In total, 384 samples were collected and cultured based on source of infection. Bacterial species identification was performed using biochemical tests, and drug susceptibility testing was done using the Kirby-Bauer disk diffusion method. The modified carbapenem inactivation method was employed for carbapenemase detection. Data were analysed using Statistical Package for the Social Sciences.

RESULTS: The overall rate of CP-CRE infection was 14.6%. Bloodstream infections and urinary tract infections were the predominant hospital-acquired infections (HAIs). The majority of CP-CRE were Escherichia coli and Klebsiella pneumoniae, and accounted for 4.9%. Chronic underlying disease (adjusted odds ratio (AOR): 7.9, 95% confidence interval (CI): 1.9-31.5), number of beds per room (AOR: 11, 95% CI: 1.7-75) and eating raw vegetables (AOR: 11, 95% CI: 3.4-40) were significantly associated with hospital-acquired CRE infection.

CONCLUSIONS: The rate of CP-CRE infection found in this study is concerning. There is a need for further evaluation of risk factors and measures to decrease HAI. Hand hygiene, increased laboratory capacity, improved infection prevention measures, and antimicrobial stewardship programmes are needed in healthcare settings to halt the transmission of CP-CRE.

PMID:37009574 | PMC:PMC10050477 | DOI:10.1016/j.ijregi.2023.02.008

IJID Reg. 2023 Mar 5;7:116-123. doi: 10.1016/j.ijregi.2023.03.001. eCollection 2023 Jun.

ABSTRACT

OBJECTIVE: To investigate the prevalence, intensity, clinical aspects and factors associated with tungiasis infection among primary school children in Northeastern Tanzania.

METHODS: A quantitative school-based cross-sectional study was conducted among 401 primary school children. Participants were assessed through clinical examination to look for embedded Tunga penetrans in their hands, feet, arms and legs. A structured questionnaire was used to enquire about factors associated with tungiasis infection. The data were analysed using descriptive statistics, Chi-squared test and logistic regression, with p<0.05 taken to indicate significance.

RESULTS: The overall prevalence of tungiasis infection was 21.2%. Of the 85 tungiasis-infested children, 54 [63.5%, 95% confidence interval (CI) 53.1-74.1] had mild infection, 25 (29.4%, 95% CI 19.0-39.6) had moderate infection, and six (7.1%, 95% CI 1.2-12.9) had heavy infection. A moderate level of knowledge was significantly associated with high odds of tungiasis infection [adjusted odds ratio (AOR) 3.16, 95% CI 1.50-6.67], while not keeping a dog/cat at home was a protective factor (AOR 0.47, 95% CI 0.25-0.89).

CONCLUSIONS: Moderate prevalence of tungiasis infection was observed among primary school children favoured by factors related to the host, parasitic agent and environment. There is a need for a health education programme in schools encouraging use of appropriate footwear (closed shoes), use of locally accessible repellents (coconut oil), fumigation of households, and washing dogs/cats with insecticides.

PMID:37009573 | PMC:PMC10063396 | DOI:10.1016/j.ijregi.2023.03.001

Soc Sci Humanit Open. 2023;7(1):100486. doi: 10.1016/j.ssaho.2023.100486. Epub 2023 Mar 27.

ABSTRACT

Social, economic, and demographic characteristics influence public disaster risk perception, including the risk of COVID-19. Migrant workers are one the most vulnerable groups to disasters. More than four million Nepali migrant workers are employed abroad, and millions are working in cities and towns in the country. This study analyzes how the social, economic, and demographic conditions of returning Nepali migrant workers determine their risk perceptions of COVID-19. An online national survey was administered from May 10 to July 30, 2020, targeting returning Nepali migrant workers nationwide. A total of 782 responses from migrant workers were recorded, covering 67 of 74 districts. Using descriptive statistics and binary logistic regression models, the results show that migrant workers in blue-collar jobs, female, older than 29 years, with pre-existing health conditions, from low-income families, and from larger families are more likely to perceive higher risks of COVID-19. The migrant workers who believe in non-pharmaceutical COVID-19 control measures, including awareness campaigns and stay-at-home orders, have higher risk perceptions of the virus than other groups. The research contributes to identifying the program and policy priority areas to address the needs and COVID-19 vulnerabilities of returning Nepali migrant workers during and after the pandemic.

PMID:37009546 | PMC:PMC10042459 | DOI:10.1016/j.ssaho.2023.100486

J Vitreoretin Dis. 2022 Jun 9;6(6):437-442. doi: 10.1177/24741264221094683. eCollection 2022 Nov-Dec.

ABSTRACT

PURPOSE: This work aims to assess the quality, accountability, readability, accessibility, and presence of Spanish translation in online material through a Google search of “macular degeneration”.

METHODS: In this retrospective cross-sectional analysis of website results from a Google search of “macular degeneration”, the quality and accountability for each website were assessed using the DISCERN criteria and the Health on the Net Foundation Code of Conduct (HONcode) principles. All 31 sites were independently graded by 2 ophthalmologists. Readability was evaluated using an online tool. The presence of accessibility features on the website and Spanish translation was recorded. The primary outcome measure was the DISCERN and HONcode quality and accountability scores of each website. Secondary outcome measures included the readability, accessibility, and presence of Spanish translation.

RESULTS: The mean ± SD of each criterion across all 15 DISCERN questions was 2.761 ± 0.666 (out of 5). The mean HONcode score for all websites was 7.355 ± 3.123. The mean consensus reading grade level was 10.258 ± 2.49. There were no statistically significant differences in any score between the top 5 websites and the bottom 26 websites evaluated. Accessibility was available on 10 of 31 websites. Spanish translation was available on 10 of 31 websites.

CONCLUSIONS: The top 5 websites that appeared on a Google search did not have better quality or readability of online content. Improving quality, accountability, and readability can help improve patients’ health literacy regarding macular degeneration.

PMID:37009540 | PMC:PMC9954772 | DOI:10.1177/24741264221094683