Tag: nevin manimala

Int J Oral Maxillofac Surg. 2021 Aug 21:S0901-5027(21)00270-8. doi: 10.1016/j.ijom.2021.07.017. Online ahead of print.

ABSTRACT

Acemannan, a linear polysaccharide produced by Aloe vera, has been shown to have important biological effects promoting wound healing and tissue regeneration. The aim of this randomized clinical trial was to investigate the impact of acemannan in guided bone regeneration (GBR) with simultaneous implant placement. Twenty patients were randomly allocated to a test group (deproteinized bovine bone with particulate acemannan (mean size 32.45 μm)) and a control group (deproteinized bovine bone only). Twenty implants were placed with simultaneous GBR. Radiographic measurements were conducted on cone beam computed tomography (CBCT) scans immediately post-surgery and at 3 and 6 months. Vertical and horizontal dimensions of the buccal bone were measured at the implant platform (0) and at points 2, 4, 6, and 8 mm apically. The dimensional reduction of vertical and horizontal buccal bone was significantly smaller in the test group at 3 months postoperative (P < 0.05) at every position measured (0, 2, 4, 6, 8 mm), but the difference was not statistically significant at 6 months. Acemannan was found to be a safe and predictable biomaterial for GBR, which resulted in enhanced dimensional stability of the regenerated tissue at 3 months. However, these results were not replicated at 6 months. Further studies are required to document the long-term efficacy and potential of acemannan use as a supplement in bone regeneration.

PMID:34429224 | DOI:10.1016/j.ijom.2021.07.017

Eur J Dent. 2021 Aug 24. doi: 10.1055/s-0041-1731838. Online ahead of print.

ABSTRACT

OBJECTIVE: The aim of this study was to compare the direct relining technique with the indirect relining technique in relation to quality of life, satisfaction with the relining, occlusal force, and halitosis of users of acrylic complete dentures.

MATERIALS AND METHODS: Twenty bimaxillary edentulous individuals were selected. They had to use the same pair of complete dentures for a minimum of 1 year and a maximum of 5 years. The subjects were randomly divided in groups of direct relining and indirect relining of the inferior denture (n = 10). Both groups received the same silicone-based relining. The clinical tests verified the quality of life (Oral Health Impact Profile in edentulous individuals), the satisfaction with the relining, the occlusal force, and halitosis. The tests (halitosis and occlusal force) were performed initially (before the relining), immediately after the relining, and 30, 60, 90, and 180 days after the relining. The questionnaires (quality of life and satisfaction with the relining) were performed initially (before the relining), and 30, 60, 90, and 180 days after the relining.

STATISTICAL ANALYSIS: Analysis of variance and the Tukey test were used (p < 0.05).

RESULTS: There was no statistical difference comparing the two techniques in all the evaluations (p < 0.05). There was a significant statistical difference for the factor of time in all clinical tests for each relining technique (p < 0.05). The quality of life and satisfaction with the relining increased significantly 30 days after the relining when compared with the initial time point, for both techniques (p < 0.05). The occlusal force increased significantly after 90 and 180 days when compared with the initial time point, for both techniques (p < 0.05). Halitosis decreased significantly immediately after the relining when compared with the initial time point, for both techniques (p < 0.05).

CONCLUSION: Independent of the relining technique used, there was an increase in the quality of life, satisfaction with the relining, and occlusal force, as well as a reduction in the level of halitosis. Both techniques generated similar results and therefore can be options in clinical practice.

PMID:34428849 | DOI:10.1055/s-0041-1731838

Eur J Dent. 2021 Aug 24. doi: 10.1055/s-0041-1731587. Online ahead of print.

ABSTRACT

This study aimed to review clinical publications involving anterior-region resin-bonded fixed partial dentures to evaluate their survival rates vis-à-vis their materials and design. An electronic search was conducted using PubMed/MEDLINE to identify articles that reported on the longevity of anterior resin-bonded fixed dental prostheses published between 2000 and 2020. Only primary clinical studies that involved a follow-up after at least 3 years were included in this review. A statistical analysis was performed to evaluate resin-bonded fixed dental prostheses’ survival rates in relation to their materials and design. This review ultimately included 23 clinical publications, comprising prospective studies, retrospective studies, and randomized controlled trials. Its statistical analysis estimated the studied prostheses’ 5-year survival rate at 86.2% for metal-framed prostheses, 87.9% for zirconia prostheses, 93.3% for alumina prostheses, 100% for glass or ceramic prostheses, and 81.7% for fiber-reinforced composite restorations. Failure rates did not significantly differ between the different material groups or between the single- and double-retainer groups. Resin-bonded fixed dental prostheses present excellent 5-year clinical longevity in the anterior sector and a favorable benefit/risk/cost ratio. Currently, no consensus has been established on an ideal material for these restorations. Cantilever design tends to limit constraints on the prostheses’ retainers and, thus, increases their survival time. All-ceramic cantilever fixed partial dentures can be considered as a definitive therapy, given their high success and survival rates. They are an optimal solution for adolescents or young adults facing potentially continuous growth.

PMID:34428850 | DOI:10.1055/s-0041-1731587

Eur J Dent. 2021 Aug 24. doi: 10.1055/s-0041-1727552. Online ahead of print.

ABSTRACT

MATERIALS AND METHODS: A sample of 62 patients were selected prior to the orthodontic treatment from a population that attended the International Islamic University Malaysia Specialist Orthodontic Clinic. Based on the lateral cephalometric analysis, the subjects were grouped into Class I, Class II, and Class III facial skeletal patterns, according to Eastman and Wits appraisal. Subsequently, unstimulated saliva samples were taken and purified to undergo leptin enzyme-linked immunosorbent assay analysis to determine the levels of leptin hormone. Statistical analysis using the Kruskal-Wallis test was used to analyze the data obtained.

RESULTS: The results showed that there was a significant difference between the levels of leptin hormone between Class I and Class II skeletal patterns and between Class I and Class III facial skeletal patterns. No statistical difference was noted between the levels of leptin of Class II and Class III facial skeletal patterns.

CONCLUSION: Salivary leptin hormone levels are higher in patients with Class II and Class III facial skeletal patterns compared with Class I.

PMID:34428845 | DOI:10.1055/s-0041-1727552

Eur J Dent. 2021 Aug 24. doi: 10.1055/s-0041-1728237. Online ahead of print.

ABSTRACT

OBJECTIVES: The aim of this study was to evaluate the effects of in-office and at-home bleaching agent applications on the surface topography and microhardness of artificially demineralized enamel.

MATERIALS AND METHODS: A total of 224 enamel specimens were prepared using bovine sound central incisors. 4 mm × 4 mm enamel windows were exposed on the buccal surfaces covering the remaining surface with nail varnish. Samples were immersed in a demineralizing solution for 16 hours to produce artificial caries lesions, then divided into four groups according to the bleaching agent’s type and concentration. Group I; in-office bleaching 35% hydrogen peroxide (HP) (Whiteness HP Maxx; FGM, Brazil), Group II and Group III at-home bleaching 16 and 22% carbamide peroxide CP, respectively (Whiteness Perfect). Group IV; control (not bleached). The microhardness Vickers hardness number (VHN) was measured at the baseline, after demineralization, and after bleaching consequently. The micro-surface changes of the enamel surface after demineralization and bleaching were evaluated by scanning electron microscope (SEM).

STATISTICAL ANALYSIS: Data were evaluated by the one-way analysis of variance (ANOVA) test followed by Post Hoc Tukey’s and Fisher’s least significant difference. Tow- sided p-values were considered statistically significant at p ≤ 0.05.

RESULTS: A significant reduction was noticed in the enamel microhardness after demineralization p < 0.05. However, there is no statistically significant difference between the mean VHN of the demineralized and bleached enamel (p > 0.001). SEM images showed significant changes on the surface of the demineralized enamel after bleaching (pattern type III).

CONCLUSIONS: The low and high concentrations of HP and CP bleaching agents increased the demineralization severity of artificial caries lesions without significantly altering their microhardness values.

PMID:34428848 | DOI:10.1055/s-0041-1728237

Eur J Dent. 2021 Aug 24. doi: 10.1055/s-0041-1729677. Online ahead of print.

ABSTRACT

OBJECTIVE: The objective of this study was to evaluate the hemostatic activity of the sap from Jatropha mollissima (Pohl) Baill. in rats.

MATERIALS AND METHODS: Twenty-four Wistar rats were randomized into four groups (n = 6): the JM25 and JM40 groups were treated with ethanolic extract from the sap of J. mollissima, in a concentration of 25 and 40 mg·mL¹, respectively; the MO group was treated with Monsel’s solution and the control group SC with a 0.9% sodium chloride solution.

STATISTICAL ANALYSIS: Data were submitted to the Kurskal-Wallis’ test, followed by Dunn’s post hoc (p < 0.05).

RESULTS: There was a significant reduction in the bleeding time of the group from the JM25 extract (p = 0.001) when compared with MO and SC. There were no statistically significant differences between groups JM25 and JM40 (p > 0.05). The JM25 group did not present rebleeding, a result significantly different from the MO group (p = 0.001). Monsel’s solution showed significant bleeding, six times greater than the control group SC.

CONCLUSION: The J. mollissima extract, in the concentration of 25 mg·mL¹, showed the highest hemostatic efficiency and was found to be a promising biomaterial for the elaboration of a hemostatic product.

PMID:34428842 | DOI:10.1055/s-0041-1729677

Eur J Dent. 2021 Aug 24. doi: 10.1055/s-0041-1731888. Online ahead of print.

ABSTRACT

OBJECTIVE: The focus of this study was to evaluate the biocompatibility of ionomer cements modified with ethanolic extracts of propolis (EEP) in different concentrations and time intervals.

MATERIALS AND METHODS: In total, one hundred and thirty-five male Wistar rats were randomized into nine groups: Control, Groups Meron, and Groups Ketac (conventional, and added with 10, 25, 50% EEP, respectively). Histological analyses of inflammatory infiltrate and collagen fibers, and immunohistochemistry of CD68+ for macrophages (MOs) and multinucleated giant cells (MGCs) were performed.

STATISTICAL ANALYSIS: Data were analyzed using the Kruskal-Wallis and Dunn (p < 0.05) tests.

RESULTS: Intense inflammatory infiltrate was demonstrated in the cements with 10% EEP at 7 days and 15 days (p < 0.05), only Group Ketac 10% EEP (p = 0.01) at 30 days. A smaller quantity of collagen fibers was observed in the cements with 10% EEP (p = 0.01) at 7 days, and Group Meron 10% EEP (p = 0.04) at 15 days. MOs and MGCs showed significant difference for the cements with 10% EEP (p = 0.01) at 7 and 15 days. At 30 days, MOs persisted in the Groups with 10% EEP.

CONCLUSIONS: The concentration of 10% EEP had the greatest influence on the inflammatory and tissue repair processes. The concentrations of 25 and 50% EEP demonstrated biocompatibility similar to that of cements that did not receive EEP.

PMID:34428843 | DOI:10.1055/s-0041-1731888

Eur J Dent. 2021 Aug 24. doi: 10.1055/s-0041-1727556. Online ahead of print.

ABSTRACT

OBJECTIVES: The aim of this study was to evaluate the microbiological and mechanical properties of glass ionomer cement (GIC) modified by chlorhexidine (CLX) for the purpose of cementing bands to the teeth of orthodontic patients.

MATERIALS AND METHODS: Ten patients, between the ages of 19 and 33 years, in the initial stage of orthodontic treatment, were randomly designated to two groups using the split-mouth design (n = 10). One group (GICEX) had bands cemented with GIC modified by CLX and a Control group (GIC), evaluated at time intervals before (T0), 3 months (T3), and 6 months (T6) after cementation. Total microbiological counts were performed, and color stability of tooth enamel, salivary pH, and the adhesive remnant index (ARI) were evaluated.

STATISTICAL ANALYSIS: The Friedman and Dunn’s tests, Mann-Whitney, one-way analysis of variance, and Tukey, and paired and non-paired t-tests (p< 0.05) were used.

RESULTS: In T3, there was evidence of significant reduction in the quantity of colony forming unit (CFU) in GICEX group in comparison with the Control (p = 0.041). In T6, the quantity of CFU was similar to the quantity in T3 and significantly different to control (p = 0.045); Control group demonstrated a similar quantity of CFU between the experimental time intervals (p = 0.066). Salivary pH demonstrated significant difference only between the time intervals T0 and T6 (p = 0.022). The tooth enamel color (p = 0.366) and ARI (p = 0.343) values demonstrated no significant changes.

CONCLUSION: The incorporation of CLX into GIC demonstrated effective antibacterial action, allowed a good bond of the cement to the enamel, a high rate of survival of the bands, did not change the color of the tooth enamel, and maintained the salivary pH at physiological levels.

PMID:34428840 | DOI:10.1055/s-0041-1727556

Eur J Dent. 2021 Aug 24. doi: 10.1055/s-0041-1731852. Online ahead of print.

ABSTRACT

OBJECTIVE: The aim of this study is to test knowledge, attitudes, and behavior of the students from the Bjelovar University of Applied Sciences in relation to oral health, and to determine the respectable differences between students of nursing and technical study programs.

PARTICIPANTS AND METHODS: Students were randomly selected to represent a convenient sample. A total of 140 students from nursing and technical studies were interviewed by using the World health organization Oral Health Questionnaire, adapted to fit the study purposes.

STATISTICAL ANALYSIS: Descriptive statistics were used to determine frequency distribution and percentages for all variables. Pearson’s Chi-square test was used to compare the proportions. A p-value less than 0.05 was considered to be statistically significant.

RESULTS: The distribution of participants regarding gender was significantly different between the study programs (p = 0.000). Significant difference was also observed in their perceived socioeconomic status (p = 0.001). A significant difference was found between the study programs regarding the knowledge whether bad teeth could impair general health (p = 0.001), could tooth decay and periodontal disease may be prevented (p = 0.002), as well as the importance of regular dental check-ups for prevention of tooth decay (p = 0.028). There were significant differences regarding dietary habits and alcohol consumption in the past 30 days between the observed study programs (p = 0.000) while no significant differences were found regarding tobacco and tobacco product use (p = 0.170).

CONCLUSION: Results obtained and presented in this paper show better knowledge and more favorable habits and behaviors among the students from nursing study program compared with the technical ones. Still all students’ habits should be changed to improve oral health. To change attitudes and influence habits, effective oral health promotion programs are needed; not only in colleges, but also in primary and secondary schools.

PMID:34428841 | DOI:10.1055/s-0041-1731852

J Cogn Neurosci. 2021 May 1;33(6):1197-1209. doi: 10.1162/jocn_a_01709.

ABSTRACT

Does early exposure to cognitive and linguistic stimulation impact brain structure? Or do genetic predispositions account for the co-occurrence of certain neuroanatomical phenotypes and a tendency to engage children in cognitively stimulating activities? Low socioeconomic status infants were randomized to either 5 years of cognitively and linguistically stimulating center-based care or a comparison condition. The intervention resulted in large and statistically significant changes in brain structure measured in midlife, particularly for male individuals. These findings are the first to extend the large literature on cognitive enrichment effects on animal brains to humans, and to demonstrate the effects of uniquely human features such as linguistic stimulation.

PMID:34428792 | DOI:10.1162/jocn_a_01709