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Evaluation of the Efficacy of Different Agents on Decontamination of Dental Implant Surface: An In Vitro Study

J Contemp Dent Pract. 2025 Feb 1;26(2):151-154. doi: 10.5005/jp-journals-10024-3788.

ABSTRACT

BACKGROUND: The current investigation aimed to evaluate the effectiveness of two different agents in decontaminating the surface of dental implants.

MATERIALS AND METHODS: For this investigation, a total of 45 dental implants were used. In a solution of 40% brain heart infusion (BHI) and 60% entire unstimulated saliva, biofilms were grown on 45 dental implants which were divided into 3 decontamination groups at random (n = 15): Group I: Control group; group II: Ozonated water; group III: Chlorhexidine group. Processed samples were examined using Scanning electron microscopy (SEM) with a backscattered electron detector and a 25 kV image resolution. Data was gathered and analyzed statistically.

RESULTS: The maximum biofilms removed in the 2% chlorhexidine group was 1.24 ± 0.10 followed by the ozonated water group was 1.40 ± 0.01 and the control group was 2.04 ± 0.16. And there was a statistically significant difference found between the three groups. On pairwise comparison, a statistically significant difference was found between the control group vs ozonated water and the control group vs 2% chlorhexidine groups. There was no significant difference found between ozonated water vs 2% chlorhexidine groups.

CONCLUSION: The present study concluded that both of the decontamination agents employed were successful in removing biofilm from the implant surface. But 2% chlorhexidine group is slightly superior to the ozonated water group in removing biofilm from the implant surface.

CLINICAL SIGNIFICANCE: The most crucial steps in treating peri-implantitis are removing polymicrobial biofilm and decontaminating the implant surface. The soft and hard tissues around dental implants are impacted by an inflammatory reaction known as peri-implantitis. At the peri-implant crevice level, the implant and abutment surface are colonized by an aggressive polymicrobial biofilm, so the removal of biofilm is important to prevent the condition. How to cite this article: Dash K, Rathod A, Sundaran MV, et al. Evaluation of the Efficacy of Different Agents on Decontamination of Dental Implant Surface: An In Vitro Study. J Contemp Dent Pract 2025;26(2):151-154.

PMID:40444509 | DOI:10.5005/jp-journals-10024-3788

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Comparative Evaluation of 5% Pyrophosphate-containing Toothpaste with a Standard Fluoridated Toothpaste in the Inhibition of Calculus Formation: A Single-blind Randomized Controlled Clinical Trial

J Contemp Dent Pract. 2025 Feb 1;26(2):144-150. doi: 10.5005/jp-journals-10024-3818.

ABSTRACT

AIM: This study compared the quantitative assessments of calculus before and after using 5% pyrophosphate-containing toothpaste and fluoridated toothpaste.

MATERIALS AND METHODS: A set of mouth mirrors, UNC-15 periodontal probes, 5% pyrophosphate-containing toothpaste, fluoridated toothpaste, and soft-bristled toothbrushes were used. The indices used were the Volpe-Manhold index (VMI), gingival index (GI), and plaque index (PI). The sample size was calculated using the independent sample t-test. Simple block randomization was followed. A p-value of less than 0.05 was considered statistically significant. Out of the 35 patients who participated, 62.85% were male and 37.14% were female, with a mean age of 26.3 years. The VMI scores in both male and female subjects decreased over 6- and 12-weeks intervals, irrespective of their enrollment in control or test groups, but it did not show a statistically significant difference (p = 0.271).

RESULTS: There was a decrease in the GI scores over 6- and 12-weeks intervals, and it was not statistically significant in the test group as compared with the control group (p = 0.223). There was also a decrease in the PI scores over 6- and 12-weeks intervals. In the test group, PI scores were better and statistically significant than those of the control group (p = 0.006).

CONCLUSION: A 5% pyrophosphate-containing dentifrice, used twice daily for 2 minutes for 3 months compared with a fluoridated dentifrice, did not cause a statistically significant difference in calculus reduction.

CLINICAL SIGNIFICANCE: Pyrophosphate is largely used due to its capacity to inhibit the mineralization of plaque and calculus formation on enamel, but well-controlled studies are meager on a 5% concentration. Therefore, it is important to develop studies focused on the capacity of the pyrophosphate to inhibit calculus formation. How to cite this article: Bhogi V, Kumar S, Reddy MS, et al. Comparative Evaluation of 5% Pyrophosphate-containing Toothpaste with a Standard Fluoridated Toothpaste in the Inhibition of Calculus Formation: A Single-blind Randomized Controlled Clinical Trial. J Contemp Dent Pract 2025;26(2):144-150.

PMID:40444508 | DOI:10.5005/jp-journals-10024-3818

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Evaluation of Frictional Resistance in Different Bracket Systems with Different Orthodontic Archwires: An In Vitro Study

J Contemp Dent Pract. 2025 Feb 1;26(2):137-143. doi: 10.5005/jp-journals-10024-3825.

ABSTRACT

AIM: This study evaluated the static frictional resistance of different self-ligating brackets (SLBs) and a conventional stainless steel (SS) bracket with two different archwire alloys during sliding mechanics.

MATERIALS AND METHODS: A total of 96 maxillary canine brackets were divided into four groups (24 Mini DiamondTM conventional SS brackets, 24 DamonTM Q2 metal passive SLBs, 24 EmpowerTM 2 metal active SLBs, and 24 DamonTM Clear 2 ceramic passive SLBs). These were tested with SS and titanium-molybdenum alloy (TMA) archwires, each measuring 0.019 × 0.025 in. The frictional resistances were measured using a Universal Testing Machine as the brackets were drawn vertically along the straight segments of the archwire. A two-way analysis of variance (ANOVA), a one-way ANOVA with a post-hoc Tukey test, and a Student t-test were used for statistical analysis.

RESULTS: The lowest mean of static frictional resistance was observed in two passive bracket groups, followed by active group and conventional group. Significant differences were found between bracket groups with SS and TMA archwires (p < 0.001), except between two passive groups, where no significant differences were found (SS: p = 0.193, TMA: p = 0.415). Among the archwires, the TMA had significantly higher static frictional resistance than SS with Mini DiamondTM (p < 0.001) and EmpowerTM 2 (p < 0.001), while there were no significant differences in frictional resistance between the SS and TMA archwires with DamonTM Q2 (p = 0.145) and DamonTM Clear2 (p = 0.470).

CONCLUSION: The selection of bracket systems and wire material significantly influences the frictional resistances in sliding mechanics. When TMA archwires are used for sliding mechanics, passive appliances can minimize frictional resistances.

CLINICAL SIGNIFICANCE: The frictional resistances at the bracket-archwire-ligation connection significantly influence orthodontic tooth movement, which in turn affects treatment time. This study assesses the frictional resistances of different SLBs and conventional brackets with different archwires, which allows orthodontists to select the most effective bracket/archwire combination for minimizing frictional resistances. How to cite this article: Al-Dulaimi FK, Albelasy NF, Mohammad MH, et al. Evaluation of Frictional Resistance in Different Bracket Systems with Different Orthodontic Archwires: An In Vitro Study. J Contemp Dent Pract 2025;26(2):137-143.

PMID:40444507 | DOI:10.5005/jp-journals-10024-3825

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Determinants of Harmonious Facial Profile in Indonesian Javanese Children: Photogrammetric Analysis of 12-14-year-old Students

J Contemp Dent Pract. 2025 Feb 1;26(2):132-136. doi: 10.5005/jp-journals-10024-3826.

ABSTRACT

AIM: The aim of this study was to identify the determinants of harmonious facial profile in children aged 12-14-year-old Indonesian with Javanese ethnic group using photogrammetry.

MATERIALS AND METHODS: This observational, cross-sectional study included 150 standardized facial profile photos of Indonesian Javanese children (75 boys and 75 girls) that were classified into three groups: less harmonious, harmonious, and very harmonious. Facial convexity angle, nasofacial angle, nasolabial angle, and mentolabial angle as determinants of facial profile were measured with Corel Draw Graphics Suite X7. The results of this study were statistically analyzed using the ANOVA test with a 95% confidence level in SPSS software.

RESULTS: Facial profile determinants were significantly different (p < 0.05) among groups. Facial convexity angle and nasofacial angle were different in boys, whereas in girls, the differences were observed in the facial convexity and nasolabial angle. In boys, harmonious facial profiles were defined with facial convexity angle (166.87 ± 5.13°) and nasofacial angle (29.91 ± 3.09°), meanwhile, in girls, harmonious facial profiles were determined by total facial convexity angle (113.57 ± 7.71°) and facial angle (168.87 ± 5.78°).

CONCLUSION: Determinants of facial profile harmony in Indonesian Javanese children aged 12-14-year-old were facial convexity angle and nasofacial angle in boys and facial profile angle and nasolabial angle in girls.

CLINICAL SIGNIFICANCE: Determinants of harmonious facial profile in Indonesian Javanese children a valuable data for orthodontic diagnosis and treatment evaluation. How to cite this article: Andini AD, Kuswandari S. Determinants of Harmonious Facial Profile in Indonesian Javanese Children: Photogrammetric Analysis of 12-14-year-old Students. J Contemp Dent Pract 2025;26(2):132-136.

PMID:40444506 | DOI:10.5005/jp-journals-10024-3826

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Effectiveness of Photobiomodulation with and without Hyaluronic Acid Gel on Gingival Depigmentation: A Randomized Control Clinical Trial

J Contemp Dent Pract. 2025 Feb 1;26(2):127-131. doi: 10.5005/jp-journals-10024-3811.

ABSTRACT

AIM: To evaluate the efficacy of low-level laser therapy and hyaluronic gel in the management of gingival hyperpigmentation.

MATERIALS AND METHODS: Sixty patients willing to receive treatment for gingival depigmentation were grouped into the following three groups: group I – laser-assisted gingival depigmentation (n = 20); group II – low-level laser-assisted gingival depigmentation (n = 20); and group III – low level laser-assisted gingival depigmentation with hyaluronic acid (n = 20). The clinical effectiveness of the depigmentation procedure as per patient’s opinion of mean smile perception changes was assessed using a visual analog scale (VAS) scoring line (0-10 cm) at preoperative (T0), on 7th day (T1) and 21st day (T2) with the question “How do you classify your smile?” with a rating from 0 – not attractive to 10 – completely attractive. Data were compiled in a Microsoft Office Excel worksheet and subjected to statistical analysis. The Mann-Whitney U test and Friedman test was done for inter- and intragroup comparison, respectively. Statistical significance was set at p-value < 0.05.

RESULTS: In group I, the VAS scores at baseline (T0), T1, and T2 were 7.60, 5.00, and 3.4, respectively, while in group II, the VAS scores at T0, T1, and T2 were 8.80, 4.40, and 3.5, respectively. The VAS scores in group III were 7.90, 1.0, and 0.4 at T0, T1, and T2, respectively. The smile perception changes (VAS scores) were lesser in group III, followed by group II and group I at T0, T1, and T2 intervals. The differences were statistically significant.

CONCLUSION: Photobiomodulation combined with hyaluronic gel topical application can produce superior results with very minimal recurrence. This noninvasive modality can be an effective alternative to invasive surgical depigmentation procedures.

CLINICAL SIGNIFICANCE: Gingival depigmentation is a common esthetic procedure. Laser-assisted depigmentation with hyaluronic acid can overcome the tissue necrosis caused by heat produced by laser and hastens healing. Photobiomodulation with hyaluronic acid can be a better alternative to invasive surgical depigmentation procedures. How to cite this article: Narayanan K, Vinayagam R, Balaji A, et al. Effectiveness of Photobiomodulation with and without Hyaluronic Acid Gel on Gingival Depigmentation: A Randomized Control Clinical Trial. J Contemp Dent Pract 2025;26(2):127-131.

PMID:40444505 | DOI:10.5005/jp-journals-10024-3811

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Evaluating Lip Repositioning for the Treatment of Excess Gingival Display with and without Pretreatment with Botox: A Randomized Clinical Trial

J Contemp Dent Pract. 2025 Feb 1;26(2):119-126. doi: 10.5005/jp-journals-10024-3831.

ABSTRACT

OBJECTIVES: To evaluate and compare the treatment of excessive gingival display (EGD) with lip repositioning surgery (LRS), with or without presurgical Botox injection, using relapse as the primary outcome.

MATERIALS AND METHODS: Twenty-two periodontally healthy patients with EGD were recruited and allocated into two equal groups. The intervention group (n = 11) underwent LRS with Botox preinjection into the smile muscles 1-2 weeks before surgery, while the control group (n = 11) underwent only LRS. Participants were assessed for changes in gingival display and lip length at 3, 6, 9, and 12 months, as well as for pain and satisfaction. The data were recorded and statistically analyzed.

RESULTS: The control group showed a statistically significant change in gingival display at 3 months (3.82 ± 2.09 mm) and 6 months (4.68 ± 1.72 mm) compared to baseline (5.91 ± 1.45 mm), but no significant changes at 9 months (5.55 ± 1.37 mm) and 12 months (5.64 ± 1.50 mm). The intervention group demonstrated a significant reduction in gingival display at 3 months (2.23 ± 1.29 mm) and 6 months (3.95 ± 1.39 mm), with stable results up to 12 months (4.27 ± 1.10 mm). The overall reduction in gingival display was significantly greater in the intervention group compared to the control group (1.86 mm, 0.27 mm, respectively). Patient satisfaction with the treatment was not significantly different between the two groups, except for willingness to repeat the procedure. Pain scores were significantly higher in the control group than in the Botox group at 24 h, with no significant differences at 3 and 7 days.

CONCLUSIONS: Botox pre-injection for LRS demonstrated its efficacy for management of EGD by enhancing lip length, reducing relapse, alleviating postoperative discomfort, and providing sustained results for 1 year.

CLINICAL SIGNIFICANCE: This study addresses effective treatments for EGD, improving esthetics and confidence. By evaluating LRS with and without Botox, it offers practical insights that improves EGD and reduces relapse, resulting in increased patient satisfaction and sustained results over a year. How to cite this article: Ghoniem OM, Madkor GG, Darhous MS. Evaluating Lip Repositioning for the Treatment of Excess Gingival Display with and without Pretreatment with Botox: A Randomized Clinical Trial. J Contemp Dent Pract 2025;26(2):119-126.

PMID:40444504 | DOI:10.5005/jp-journals-10024-3831

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Perceptions of chiropractic students on digital literacy skills at a South African university: A cross-sectional study

J Chiropr Educ. 2025 May 31;39:eJCE-24-21. doi: 10.7899/JCE-24-21.

ABSTRACT

OBJECTIVE: The purpose of this study was to assess chiropractic students’ opinions of their digital literacy proficiencies.

METHODS: A cross-sectional, quantitative, and exploratory study was conducted with 1st to 4th year bachelor of health sciences and 1st to 2nd year master of health sciences chiropractic students (n = 244) at the University of Johannesburg using an anonymous, self-administered online Likert-style questionnaire. The 41-item survey collected demographic data and students’ self-perceptions on 4 aspects of digital literacy skills, namely, information literacy (IL), information communications technology literacy (ICTL), information and communications technology utilization (ICTU), and media literacy (ML). Data were analyzed according to the 4 constructs.

RESULTS: The response rate was 57.78% (n = 141). The majority of students were 18-24 years of age and female and the highest year cohort was from 1st year master of health sciences chiropractic students. Students reported high levels of agreement within IL (M = 4.220; SD = .472), and ML (M = 4.271; SD = .507) constructs and lower levels of agreement within ICTL (M = 3.808; SD = .568) and ICTU (M = 3.762; SD = .562) constructs. Age and sex were not statistically significant; academic year was significant for IL only (p = .040). All 4 constructs exhibited acceptable internal consistency (IL: 0.862; ICTL: 0.830; ICTU: 0.840; ML: 0.844).

CONCLUSION: Gaps were highlighted in the perception of ICTL and ICTU skills in all chiropractic students and trends emphasizing differences between basic and higher order levels of digital literacy skills between junior and senior years of study, respectively. There is a need to bridge the gap in skills at department, faculty, and university levels.

PMID:40444473 | DOI:10.7899/JCE-24-21

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Prevalence of burnout among chiropractic students in Malaysia

J Chiropr Educ. 2025 May 31;39:eJCE-24-19. doi: 10.7899/JCE-24-19.

ABSTRACT

OBJECTIVE: To investigate the prevalence of burnout among chiropractic students in Malaysia, using the Maslach Burnout Inventory-General Survey for Students (MBI-GS[S]).

METHODS: A quantitative cross-sectional study was conducted at IMU University with 219 chiropractic students from semester 1 through semester 8. The MBI-GS(S) was utilized to assess burnout across 3 subscales: Exhaustion, Cynicism, and Professional Efficacy. Data were analyzed using descriptive statistics, Kruskal-Wallis tests, and χ2 tests. Standardized residual analysis was performed as a posthoc step to identify which specific year(s) contributed to any significant χ2 results.

RESULTS: Of the 219 participants, 2.28% were classified as having a burnout profile under the 2016 method, while 10.04% met the burnout profile under the 2018 method. A χ2 test revealed no association between year of study and burnout using the 2016 method. In contrast, the 2018 method indicated a significant association (p = .004), driven primarily by a higher-than-expected frequency of burnout in Year 1 and a lower-than-expected frequency in Year 2.

CONCLUSION: Burnout is present among chiropractic students in Malaysia, with estimates differing by classification method. The 2018 method not only yielded a higher overall prevalence but also highlighted an association with year of study. These findings underscore the importance of choosing appropriate classification criteria and emphasize targeted interventions for students most at risk, particularly in their first year.

PMID:40444472 | DOI:10.7899/JCE-24-19

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[Corrigendum] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Mol Med Rep. 2025 Aug;32(2):216. doi: 10.3892/mmr.2025.13581. Epub 2025 May 30.

ABSTRACT

Following the publication of the above article, the authors have drawn to the Editor’s attention that a number of corrections are required to four figures featured in the above article, and a textual change is also required in the Results section. Concerning the textual change, in the last sentence of the first paragraph of the Results on p. 4, “…Schischk and 11 for Angelica sinensis (Oliv) Diels”, should have read as: “…Schischk and 10 for Angelica sinensis (Oliv) Diels”, as shown correctly in Fig. 1C on p. 5. Secondly, concerning the flow cytometric (FCM) data shown in the right‑hand flow chart in the second row of Fig. 5E, the authors have realized that these data were inadvertently copied across from the third flow chart in the first row of Fig. 4C. After examining their original data, the authors have realized that the second flow chart in the second row of Fig. 5E was misplaced (showing the results from the “siPARP1+H2O2” experiment), and the corrected version of this figure is presented in this corrigendum (the corresponding statistical graph shown in Fig. 5F has been replaced as well). Thirdly, concerning the western blot data shown in Fig. 8 on p. 11, the β‑actin internal reference proteins pertaining to the cleaved‑caspase‑3, PARP1 and cleaved‑PARP1 experiments were selected incorrectly for this figure. These data, and the corresponding statistical graphs shown in Fig. 8A‑D, have been corrected in the new version of Fig. 8 provided in this corrigendum. Fourthly, the FCM flow charts to represent the “3,200 µg/ml RJNTF” and “PJ34 inhibitor group” experiments in Fig. 9C on p. 12 were wrongly placed, and both these data and the corresponding statistical graphs have also been corrected in the revised version of Fig. 9 included in this corrigendum. Finally, in Fig. 10 on p. 13, “$” in Fig. 10D (relating to the statistical analysis of the data) should have been written as “ns”, and in the corresponding figure legend, “$P<0.05 vs. RJNTF group” should have been written as “nsP<0.05 vs. 1,600 µg/ml RJNTF group”. These corrections have been attended to in the revised version of Fig. 10 provided in this corrigendum. All the authors approve of the publication of this corrigendum, and the authors are grateful to the Editor of Molecular Medicine Reports for granting them the opportunity to publish this. The authors regret that these errors were included in the paper, and also apologize to the readership for any inconvenience caused. [Molecular Medicine Reports 29: 102, 2024; DOI: 10.3892/mmr.2024.13226].

PMID:40444460 | DOI:10.3892/mmr.2025.13581

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Gender and Marital Status are Associated with Healthy Diet Among the Oldest Old

J Appl Gerontol. 2025 May 30:7334648251343329. doi: 10.1177/07334648251343329. Online ahead of print.

ABSTRACT

Studies have shown links between nutrition in older adults and marital status. Few studies explore the interaction of gender and marital status with a healthy diet in the US for older adults. Using a sample of oldest olds living in an independent, retirement community dwelling in Florida, we found a statistically significant difference in healthful diet between women and men, controlling for marital status, health status, social isolation, loneliness, and other covariates. We also found a significant negative relationship between healthful diet and widowhood (b = -3.85, p < .000). Likewise, older adults who were divorced or never married had lower healthful diet scores than those who were married or remarried (b = -7.31, p < .000), disability was associated with a lower healthful diet (b = -.30, p < .01), and loneliness was negatively associated with healthful diet. The results have important implications for medical advisers and those involved in providing support to these older adults.

PMID:40444447 | DOI:10.1177/07334648251343329