Categories
Nevin Manimala Statistics

Estimating pixel-level uncertainty in ocean color retrievals from MODIS

Opt Express. 2022 Aug 15;30(17):31415-31438. doi: 10.1364/OE.460735.

ABSTRACT

The spectral distribution of marine remote sensing reflectance, Rrs, is the fundamental measurement of ocean color science, from which a host of bio-optical and biogeochemical properties of the water column can be derived. Estimation of uncertainty in these derived properties is thus dependent on knowledge of the uncertainty in satellite-retrieved Rrs (uc(Rrs)) at each pixel. Uncertainty in Rrs, in turn, is dependent on the propagation of various uncertainty sources through the Rrs retrieval process, namely the atmospheric correction (AC). A derivative-based method for uncertainty propagation is established here to calculate the pixel-level uncertainty in Rrs, as retrieved using NASA’s multiple-scattering epsilon (MSEPS) AC algorithm and verified using Monte Carlo (MC) analysis. The approach is then applied to measurements from the Moderate Resolution Imaging Spectroradiometer (MODIS) on the Aqua satellite, with uncertainty sources including instrument random noise, instrument systematic uncertainty, and forward model uncertainty. The uc(Rrs) is verified by comparison with statistical analysis of coincident retrievals from MODIS and in situ Rrs measurements, and our approach performs well in most cases. Based on analysis of an example 8-day global products, we also show that relative uncertainty in Rrs at blue bands has a similar spatial pattern to the derived concentration of the phytoplankton pigment chlorophyll-a (chl-a), and around 7.3%, 17.0%, and 35.2% of all clear water pixels (chl-a ≤ 0.1 mg/m3) with valid uc(Rrs) have a relative uncertainty ≤ 5% at bands 412 nm, 443 nm, and 488 nm respectively, which is a common goal of ocean color retrievals for clear waters. While the analysis shows that uc(Rrs) calculated from our derivative-based method is reasonable, some issues need further investigation, including improved knowledge of forward model uncertainty and systematic uncertainty in instrument calibration.

PMID:36242224 | DOI:10.1364/OE.460735

Categories
Nevin Manimala Statistics

Effects of color-enhancing glasses on color vision in congenital red-green color deficiencies

Opt Express. 2022 Aug 15;30(17):31182-31194. doi: 10.1364/OE.451295.

ABSTRACT

As commercially available glasses for color vision deficiency (CVD) are classified as low risk, they are not subject to stringent marketing regulations. We investigate how EnChroma and VINO glasses affect performance on the Colour Assessment and Diagnosis (CAD) test in individuals with CVD. Data were obtained from 51 individuals with red-green CVD. Blood or saliva samples were collected to examine the structure of the OPN1LW/OPN1MW array. Individuals completed the CAD test twice without glasses and once with each pair of glasses. Although there was a statistically significant effect of both glasses, only that of VINO could be considered functionally meaningful.

PMID:36242206 | DOI:10.1364/OE.451295

Categories
Nevin Manimala Statistics

Echo speckle imaging of dynamic processes in soft materials

Opt Express. 2022 Aug 15;30(17):30991-31001. doi: 10.1364/OE.459708.

ABSTRACT

We present a laser-speckle imaging technique, termed Echo speckle imaging (ESI), that quantifies the local dynamics in biological tissue and soft materials with a noise level around or below 10% of the measured signal without affecting the spatial resolution. We achieve this through an unconventional speckle beam illumination that creates changing, statistically independent illumination conditions and substantially increases the measurement accuracy. Control experiments for dynamically homogeneous and heterogeneous soft materials and tissue phantoms illustrate the performance of the method. We show that this approach enables us to precision-monitor purely dynamic heterogeneities in turbid soft media with a lateral resolution of 100 µm and better.

PMID:36242192 | DOI:10.1364/OE.459708

Categories
Nevin Manimala Statistics

Super cosh-Gauss nonuniformly correlated radially polarized beam and its propagation characteristics

Opt Express. 2022 Aug 15;30(17):30857-30869. doi: 10.1364/OE.468349.

ABSTRACT

In this paper, a new kind of partially coherent vector beam termed as super cosh-Gauss nonuniformly correlated radially polarized (SCNRP) beam is introduced. Such beam source exhibits almost perfect coherence between two points that are within the beam center region or located on a ring concentric with the beam center. However, the coherence drops or even vanishes when the two points leave the central region and are located on the concentric rings with different radii. The second-order statistical properties, such as the spectral density, the state of polarization (SOP), and the degree of polarization (DOP) of such beam upon free-space propagation are studied through numerical examples. Our results reveal that the beam displays a self-focusing property during propagation. The focusing ability can be enhanced with increasing the beam index and decreasing the beam’s spatial coherence width, whereas the DOP and SOP remain unchanged on propagation. Meanwhile, we establish an experimental system with the use of a radial polarization converter and a digital micro-mirror device to synthesize the SCNRP beam with controllable beam index and spatial coherence width. The spectral density and polarization properties of the synthesized beam during propagation are measured and analyzed in the experiment. The experimental results agree well with our theoretical predictions.

PMID:36242182 | DOI:10.1364/OE.468349

Categories
Nevin Manimala Statistics

Strong cluster synchronization in complex semiconductor laser networks with time delay signature suppression

Opt Express. 2022 Aug 15;30(17):30727-30738. doi: 10.1364/OE.464661.

ABSTRACT

Cluster synchronization is a state where clusters of nodes inside the network exhibit isochronous synchronization. Here, we present a mechanism to realize the strong cluster synchronization in semiconductor laser (SL) networks with complex topology, where stable cluster synchronization is achieved with decreased correlation between dynamics of different clusters and time delay signature concealment. We elucidate that, with the removal of intra-coupling within clusters, the stability of cluster synchronization could be enhanced effectively, while the statistical correlation among dynamics of each cluster decreases. Moreover, it is demonstrated that the correlation between clusters can be further reduced with the introduction of dual-path injection and frequency detuning. The robustness of strong cluster synchronization on operation parameters is discussed systematically. Time delay signature in chaotic outputs of SL network is concealed simultaneously with heterogeneous inter-coupling among different clusters. Our results suggest a new approach to control the cluster synchronization in complex SL networks and may potentially lead to new network solutions for communication schemes and encryption key distribution.

PMID:36242171 | DOI:10.1364/OE.464661

Categories
Nevin Manimala Statistics

Statistical properties of a partially coherent vector beam with controllable spatial coherence, vortex phase, and polarization

Opt Express. 2022 Aug 15;30(17):29923-29939. doi: 10.1364/OE.465274.

ABSTRACT

We report on a partially coherent radially polarized power-exponent-phase vortex (PC-RP-PEPV) beam with various distributions of intensity, controllable coherence width, vortex phase, and polarization. The statistical properties of the PC-RP-PEPV beam depend on topological charge, power order, polarization states, and coherence width, which differ from those of conventional radially polarized beams. Here, the initial radial polarization state will transform to complex ellipse polarization state during propagation. By modulating the topological charge of the PC-RP-PEPV beam, the intensity structure of the beam can be adjusted from circular to polygonal. Finally, PC-RP-PEPV beams were experimentally generated, and were consistent with numerical simulation results. This work has applications in optical manipulation, optical measurements, and optical information processing.

PMID:36242106 | DOI:10.1364/OE.465274

Categories
Nevin Manimala Statistics

Pulsed electromagnetic fields for post-appendicectomy pain management: a randomized, placebo-controlled trial

Trials. 2022 Oct 14;23(1):874. doi: 10.1186/s13063-022-06810-y.

ABSTRACT

BACKGROUND: The value of pulsed electromagnetic field (PEMF) in postoperative pain management, due to the inconsistent findings so far, remains unclear. We extended the evaluation of PEMF on postoperative pain and intravenous (IV) analgesic use to a group of post-appendicectomy Asian patients.

METHODS: This is a double-blinded, randomized trial. Adults with a clinical diagnosis of acute appendicitis were enrolled. Patients were allocated randomly to receive an active-PEMF device or an inactive device after the surgery in addition to the standard postoperative pain management. The primary outcome measure was the 12-h cumulative postoperative pain intensity measured at four different time points using the visual analogue scale. The secondary outcome measure was the total amount of IV fentanyl used (in mg) via PCA over the first 12 postoperative hours. The primary analysis in this trial compared the two study groups for the reported cumulative pain score (both at rest and on movement) and the cumulative amount of IV fentanyl uses over the first 12 postoperative hours using the Wilcoxon rank sum test. Analyses were performed based on the intention-to-treat principal. Multiple imputation was used to handle the missing data assuming that the data were missing at random.

FINDINGS: One hundred eighteen subjects were randomized; 58 were allocated to the active-PEMF group and 60 to the inactive control group. Pooled mean pain score of both intervention groups by time point declined in a similar fashion over the course of 12 postoperative hours. The 12-h cumulative postoperative pain score at rest and on movement did not differ significantly after the procedure. (W = 1832.5 ~ 1933.0, p-value 0.6192 ~ 0.2985 for resting pain score comparison; W = 1737.0 ~ 1804.5, p-value 0.9892 ~ 0.7296 for movement pain score comparison). For the secondary outcome measure of 12-h total fentanyl use, a comparison between the PEMF vs. placebo arm also revealed no statistically significant difference across all the 20 imputed datasets (W = 1676.5 ~ 1859.0, p-value 0.7344 ~ 0.5234).

DISCUSSION: PEMF was not superior to placebo as an adjunct pain management for up to 12 h post-appendicectomy. Previously reported effect of PEMF on postoperative pain intensity and analgesia uses in similar surgical settings cannot be verified.

TRIAL REGISTRATION: National Medical Research Register Malaysia (NMRR-15-670-25,805) and Thai Clinical Trials Registry (retrospectively registered on November 01, 2019, Study ID-TCTR20191102002).

PMID:36242089 | DOI:10.1186/s13063-022-06810-y

Categories
Nevin Manimala Statistics

Validity and reliability of a semi-quantitative food frequency questionnaire in groups at high risk for cardiovascular diseases

Nutr J. 2022 Oct 14;21(1):63. doi: 10.1186/s12937-022-00815-8.

ABSTRACT

BACKGROUND: Diet is a modifiable risk factor for cardiovascular diseases (CVD), but there is still a lack of tools to assess dietary intakes of this high-risk population in Ningxia, China.

OBJECTIVE: We aim to evaluate the validity and reliability of the semi-quantitative food frequency questionnaire (SFFQ) in the groups in Ningxia using a 24-hour dietary recall method.

METHOD: Two hundred five participants were included in the analysis. The two FFQs were 6 months apart, and during this time two 24-hour dietary recalls (24HDRs) were completed. Statistical methods were compared using inter-class correlation coefficient, unadjusted, energy-adjusted, de-attenuated correlation coefficient, quartile classification, weighted K values, and 95% limits of agreement (LOA).

RESULTS: The inter-class correlation coefficients between FFQ1 and FFQ2 ranged from 0.25 to 0.73. The number of subjects classified as identical or adjacent was 72.2 to 85.9%. The crude correlation coefficient between FFQs and 24HDRs was 0.30 ~ 0.81, the energy-adjusted correlation coefficient was 0.16 ~ 0.83, and the de-attenuated correlation coefficient was 0.19 ~ 0.98. Weighted k statistics and Bland-Altman plots showed acceptable agreement between FFQs and 24HDRs.

CONCLUSION: The FFQ developed for the population at high risk of cardiovascular and cerebrovascular diseases in areas of Ningxia can be used to measure the dietary intake of nutrients and food groups reliably and validly.

PMID:36242082 | DOI:10.1186/s12937-022-00815-8

Categories
Nevin Manimala Statistics

Selling sex in the context of substance use: social and structural drivers of transactional sex among men who use opioids in Maryland

Harm Reduct J. 2022 Oct 15;19(1):115. doi: 10.1186/s12954-022-00697-3.

ABSTRACT

BACKGROUND: Transactional sex is an important driver of HIV risk among people who use drugs in the USA, but there is a dearth of research characterizing men’s selling and trading of sex in the context of opioid use. To identify contextually specific factors associated with selling or trading sex in a US population of men who use drugs, we cross-sectionally examined social and structural correlates of transactional sex among men who use opioids (MWUO) in Anne Arundel County and Baltimore City, Maryland.

METHODS: Between July 2018 and March 2020, we used targeted sampling to recruit men reporting past-month opioid use from 22 street-level urban and suburban recruitment zones. MWUO completed a 30-min self-administered interview eliciting substance use histories, experiences with hunger and homelessness, criminal justice interactions, and transactional sex involvement. We identified correlates of recent (past 3 months) transactional sex using multivariable log-binomial regression with cluster-robust standard errors.

RESULTS: Among 422 MWUO (mean age 47.3 years, 73.4% non-Hispanic Black, 94.5% heterosexual), the prevalence of recent transactional sex was 10.7%. In multivariable analysis, younger age (adjusted prevalence ratio [aPR] 0.98, 95% confidence interval [95% CI] 0.97-0.99, p < 0.001), identifying as gay/bisexual (aPR = 5.30, 95% CI 3.81-7.37, p < 0.001), past-month food insecurity (aPR = 1.77, 95% CI 1.05-3.00, p = 0.032), and injection drug use in the past 3 months (aPR = 1.75, 95% CI 1.02-3.01, p = 0.043) emerged as statistically significant independent correlates of transactional sex.

CONCLUSIONS: Synergistic sources of social and structural marginalization-from sexuality to hunger, homelessness, and injection drug use-are associated with transactional sex in this predominantly Black, heterosexual-identifying sample of MWUO. Efforts to mitigate physical and psychological harms associated with transactional sex encounters should consider the racialized dimensions and socio-structural drivers of transactional sex among MWUO.

PMID:36242081 | DOI:10.1186/s12954-022-00697-3

Categories
Nevin Manimala Statistics

Comparison of microbial signatures between paired faecal and rectal biopsy samples from healthy volunteers using next-generation sequencing and culturomics

Microbiome. 2022 Oct 14;10(1):171. doi: 10.1186/s40168-022-01354-4.

ABSTRACT

BACKGROUND: Faecal samples are frequently used to characterise the gut microbiota in health and disease, yet there is considerable debate about how representative faecal bacterial profiles are of the overall gut community. A particular concern is whether bacterial populations associated with the gut mucosa are properly represented in faecal samples, since these communities are considered critical in the aetiology of gastrointestinal diseases. In this study we compared the profiles of the faecal and mucosal microbiota from ten healthy volunteers using bacterial culturing (culturomics) and next-generation sequencing targeting the 16S ribosomal nucleic acid (rRNA) gene. Paired fresh rectal biopsies and faecal samples were processed under stringent anaerobic conditions to maintain the viability of the bacteria. Four different sample types were analysed: faecal (F), faecal homogenised (FHg), biopsy tissue (B) and biopsy wash (BW) samples. RESULTS: There were no significant statistical differences in either bacterial richness or diversity between biopsy washes (BW) and faecal (F) or faecal homogenised (FHg) samples. Principal coordinates analysis of a Bray-Curtis distance matrix generated from sequence variant tables did not show distinct clustering between these samples (PERMANOVA; p = 0.972) but showed strong clustering of samples from individual donors. However, the rectal biopsy tissue (B) samples had a significantly altered bacterial signature with greater abundance of Proteobacteria and Acidobacteria compared to faecal (F) and faecal homogenised (FHg) samples. A total of 528 bacteria encompassing 92 distinct bacterial species were isolated and cultured from a subset of six volunteer samples (biopsy washes and faeces). This included isolation of 22 novel bacterial species. There was significant similarity between the bacterial species grown in anaerobic culture and those identified by 16S rRNA gene sequencing (Spearman correlation; rho = 0.548, p = 0.001).

CONCLUSION: This study showed that the bacterial profiles of paired faecal and rectal biopsy wash samples were very similar, validating the use of faecal samples as a convenient surrogate for rectal biopsy-associated microbiota. Anaerobic bacterial culture results showed similar taxonomic patterns to the amplicon sequence analysis disproving the dogma that culture-based methods do not reflect findings of molecular assessments of gut bacterial composition. Video abstract.

PMID:36242064 | DOI:10.1186/s40168-022-01354-4