Tag: pubmed

J Pak Med Assoc. 2021 Dec;71(12):2748-2754. doi: 10.47391/JPMA.1784.

ABSTRACT

OBJECTIVE: To analyse outcomes of breast conservation surgery and to identify the factors that could have affected the outcomes.

METHODS: The retrospective study was conducted at the Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan, and comprised data of breast conservation surgery cases done between January 2011 and October 2014 in order to cover up for the 5-year follow-up of the last enrolled patient. Data, obtained through the institutional information and database system, included disease-recurrence, 5-year disease-free survival and overall survival. Data was statistically analysed using SPSS 20.

RESULTS: Of the 553 cases, 417(75%) had no loco-regional recurrence or distant metastasis, while 136(25%) had some form of loco-regional, distant or contralateral metastasis at 5-year follow-up. In patients who had recurrence or metastasis, only progesterone receptor status, nodal status and mode of treatment showed significant association (p<0.05). Mortality at 5-year follow-up was 77(14%). Amongst the patients who died, only progesterone receptor status and nodal status had significant association (p<0.05). Five-year overall survival for the cohort was 476(86%), whereas 5-year disease-free survival was 409(74%).

CONCLUSION: Breast conservation surgery was found to have favourable outcomes, while progesterone status, nodal involvement and mode of treatment significantly affected the outcome.

PMID:35150532 | DOI:10.47391/JPMA.1784

Psychiatr Danub. 2021 Dec;33(Suppl 13):357-363.

ABSTRACT

BACKGROUND: This study was carried out to compare the fear levels and sleep problems of nurses working in wards where patients with COVID-19 are hospitalized and nurses working in wards without COVID-19 patients.

SUBJECTS AND METHODS: This descriptive, cross-sectional research was conducted on 211 nurses using a web-based online survey in Turkey (including 104 nurses working in wards where patients with COVID-19/107 nurses working in wards where patients without COVID-19).

RESULTS: When the COVID-19 Fear Scale mean scores of the nurses working in wards where patients with/without COVID-19 were compared, it was determined that the difference between the groups was statistically significant (p<0.05). When the sleep problems experienced were compared according to the Post-Sleep Inventory, it was determined that the difference between the groups was not statistically significant (p>0.05). There was a moderately significant and positive correlation between the nurses’ mean scores for the COVID-19 Fear Scale and Post-Sleep Inventory.

CONCLUSIONS: It was determined that as the fear levels of nurses increased, they experienced more sleep problems.

PMID:35150509

Psychiatr Danub. 2021 Dec;33(Suppl 13):387-391.

ABSTRACT

BACKGROUND: COVID-19 spread rapidly around the world, causing an acute infectious pneumonia pandemic. COVID-19 first seen in our country since 11 March 2020 in Turkey have also taken an epidemic form. Many social restrictions have been imposed to slow the spread, such as quarantine practices, curfews, restrictions on travel between countries / cities, restrictions on collective activities and social distance practices. In our country, formal education was suspended by the Higher Education Council and it was recommended that all processes including assessment and evaluation be carried out online. In this study, it was aimed to evaluate the psychological effects of Süleyman Demirel University Faculty of Medicine students due to the COVID-19 outbreak.

METHOD: 607 students gave opinions for the study (n=607). Generalized Anxiety Disorder-7 (GAD-7) Test was preferred in the study because it was preferred in international studies.

RESULTS: Students’ mean GAD-7 score was calculated as 10.24±3.95. 3 (0.5%) of the students were mild, 339 (55.8) were moderate, 168 (27.7%) were high and 97 (16%) were in serious anxiety. The average of anxiety of preclinical students (10.50±4.06) was calculated to be higher than the clinical period students (9.80±3.72) and a statistically significant difference was found between the two groups (p=0.028). 61 of the participants (10%) had COVID-19 positivity in themselves or in their relatives. The average of the students who had COVID-19 positivity in themselves or their close environment (11.37±4.34) was higher than the students who did not (10.12±3.89), and there was a statistically significant difference between the two groups (p=0.034). In our cross-sectional descriptive study, students’ GAD-7 mean score was 10.24±3.95, which shows that students of Süleyman Demirel University Faculty of Medicine also had high prevalent anxiety disorders during the COVID-19 epidemic, in line with the current literature. As a result of this study in which we evaluated the psychological conditions of our students during the pandemic period.

CONCLUSION: Considering that the long-term effects of anxiety disorders will continue, we believe that it will be appropriate to plan activities for post-epidemic anxiety rehabilitation of our students in the evaluation of our post-epidemic education program.

PMID:35150513

Psychiatr Danub. 2021 Dec;33(Suppl 13):308-313.

ABSTRACT

BACKGROUND: The aim of this study was to evaluate the incidence and clinical features of non-melanoma tumors of the head and neck, as well as the validity of surgical therapy in their treatment.

SUBJECTS AND METHODS: The study included 530 patients who were operated in the Otorhinolaryngology department of the Livno County Hospital.

RESULTS: In 295 cases (65.1%), it was basal cell carcinoma of the skin and was followed by squamous cell carcinoma of the skin, in 119 cases (29.9%) while the remaining 5% of cases referred to other non-melanoma skin carcinomas. Statistically significant, the most common non-melanoma skin carcinoma was basal cell carcinoma (χ²=625,67; df=4; p<0.01). The most co mmon localization was the skin of the nose (24.2%), which proved to be statistically significant (χ²=290.824; df=5; p=0.00). All patients underwent classic surgery, and in 358 cases (89.5%) the tumor was completely removed, while in 40 cases (10.5%) the tumor was partially removed which proved to be statistically significant (χ²=254,08; df=1; p=0.00).

CONCLUSIONS: The results of the study fully confirm the assertion that classical surgery is the method of choice in the treatment of non-melanoma skin cancers and in the vast majority it is proven to be sufficient.

PMID:35150500

Psychiatr Danub. 2021 Dec;33(Suppl 13):288-296.

ABSTRACT

BACKGROUND: Invasive neurosurgical treatment or minimally invasive neurosurgical treatment are methods of choice for the treatment of patients with drug resistant epilepsy. The aim of this study was to evaluate the impact of neurosurgical treatment and the quality of life of patients with drug resistant epilepsy and to determine what are the potential predictors of quality of life of patients with drug resistant epilepsy one year after neurosurgical treatment.

SUBJECTS AND METHODS: The research was performed at the Referral Centre for Epilepsy, Department of Neurology, University Hospital Centre Zagreb from February 2015 to February 2020 with Ethics commitee approval. The study included 96 patients with drug resistant epilepsy who were examined for the quality of life before and one year after neurosurgical treatment using the form questionnaire “Quality of life in epilepsy” (QOILE-31) validated Croatian 1.0 version and the questionnaire to assess the degree of depression “Beck Depression Inventory I” (BDI-I) validated Croatian version.

RESULTS: Of 96 patients with drug resistant epilepsy one year after neurosurgical treatment 46 (47.9%) patients remained completely free from epileptis seizures. Wilcoxon equivalent pair test showed that the number of epileptic seizures one year after neurosurgical treatment was significantly lower (median before neurosurgical treatment is 10; and after neurosurgical treatment is 1, p<0.001). The most informative potential statistically significant predictor variables of quality of life based on the criterion variables QOLIE-31 and BDI-I are: total disease duration in years (p=0.034), patient age (p=0.042), number of antiepileptics one year after neurosurgical treatment (p=0.001), the number of epileptic seizures per month (p=0.016), and social welfare rights (p=0.045).

CONCLUSION: Neurosurgical treatment of patients with drug resistant epilepsy significantly reduces the number of epileptic seizures which significantly improves their overall quality of life one year after neurosurgical treatment.

PMID:35150497

Psychiatr Danub. 2021 Dec;33(Suppl 13):297-303.

ABSTRACT

INTRODUCTION: Colon cancer is one of the most common malignancies. Numerous studies suggest an association between resilience and quality of life in colon cancer patients. The aim of this study was to explore the association between resilience and quality of life in people with colon cancer.

SUBJECTS AND METHODS: A cross-sectional study was conducted on a sample of 200 subjects at the Oncology Clinic of the University Clinical Hospital Mostar. Data were collected in the period between April 2019 and June 2021. A socio-demographic questionnaire specifically designed for this study, a CD-RISC-25 scale for assessing resilience, and a WHOQOL-BREF questionnaire for assessing quality of life were used for collecting data.

RESULTS: A statistically significant positive association of resilience with all domains of quality of life was found. The mental health domain contributed the most statistically significantly positively to the level of resilience. Patients who were not married had a statistically significantly higher level of resilience compared to married, divorced and widowed patients. No statistically significant difference was found in resilience levels relative to other socio-demographic factors and cancer stage. Patients treated with a combination of surgery and chemotherapy had a statistically significantly higher level of resilience compared to patients treated with other therapeutic methods.

CONCLUSIONS: Higher level of resilience statistically significantly contributes to a higher level of quality of life in people with colon cancer.

PMID:35150498

Psychiatr Danub. 2021 Dec;33(Suppl 13):255-259.

ABSTRACT

BACKGROUND: This study aimed to examine the results of Acceptance of Cosmetic Surgery Scale among the Croatian population and its correlations with other scales and demographic data.

SUBJECT AND METHODS: The sample consisted of 420 people who voluntarily filled out an online questionnaire. They completed demographic questions and four scales: Acceptance of Cosmetic Surgery Scale (ACSS), Rosenberg Self-Esteem Scale (RSES), Satisfaction With Life Scale (SWLS), and Body Appreciation Scale-2 (BAS-2).

RESULTS: ACSS scale showed five statistically significant differences between genders and a higher overall score in women, but no significant differences were recorded in three ACSS subscales and the overall ACSS score. In contrast to men, women respondents recorded a significant negative correlation between ACSS subscales score (Social, Consider) and BAS-2 and Satisfaction with life score, while a positive correlation was recorded with BMI.

CONCLUSION: The ACSS score among the Croatian population was higher than the results among the Italian and Serbian population, and similar to the original American study, which tells us that the Croatian population accepts and considers cosmetic surgery a lot. Furthermore, our results are important for practitioners and patients because they revealed correlations between ACSS scores and the self-thinking scale.

PMID:35150493

Psychiatr Danub. 2021 Dec;33(Suppl 13):278-287.

ABSTRACT

BACKGROUND: Women diagnosed with infertility and receiving infertility treatment reported high levels of depressive symptoms, anxiety and distress. Infertile women should first be screened for psychosocial risks. Psychosocial care interventions should be planned according to their needs. The aim of this methodologically designed study was to test the validity and reliability of the Screening Tool on Distress in Fertility Treatment’s (SCREENIVF) Turkish version in infertile women.

SUBJECTS AND METHODS: The present study included 323 women diagnosed with nulliparous and undergoing fertility treatment. Women filled in the descriptive characteristics questionnaire, The Copenhagen Multi-Centre Psychosocial Infertility-Fertility Problem Stress Scale (COMPI-FPSS) and the SCREENIVF.

RESULTS: To examine the contribution of the items to the scale, six items with an insufficient contribution to the scale were removed from the scale as a result of the item-total score correlation values (Corrected item-total correlation <0.25). The item-total score correlation coefficients and subscale-total score correlation coefficients obtained for each subscale ranged from 0.31 to 0.98. According to the regression equation formed in line with the multivariate linear regression model that will model the linear relationship between COMPI-FPSS, which is a scale equivalent to the subscale of the SCREENIVF, the total scores of the subscale were statistically significant predictors of the scores obtained from COMPI-FPSS, and (F=161.281, p<0.001) multiple explanatory coefficients were 77.2%. Cronbach’s alpha coefficient was 0.77 and accepted to be reliable. 16% of the women participating in this study were above the cut-off scores concerning anxiety and depression, 13.9% acceptance, 8.2% hopelessness and 2% social support. The scale consisted of five subscales and 28 items.

CONCLUSION: The findings indicate that the Turkish version of SCREENIVF is a valid and reliable measurement tool that can be used in the routine assessment regarding psychosocial aspects in the infertility treatment process.

PMID:35150496

Acta Paediatr. 2022 Feb 12. doi: 10.1111/apa.16289. Online ahead of print.

ABSTRACT

AIM: Tongue tie is a common problem affecting breastfeeding due to poor infant latch and/or maternal pain. Evidence of whether treatment improves breastfeeding outcomes is conflicting. We conducted a systematic review and meta-analysis to examine the effectiveness of tongue tie treatment on breastfeeding difficulties.

METHODS: We searched peer-reviewed and grey literature in MEDLINE (OVID), PubMed, CINAHL Plus, EMBASE and PsycINFO, from 01/1970 to 09/2019. Inclusion: randomized and non-randomized clinical trials, and quasi-experimental study designs, involving breastfeeding interventions for full-term singleton infants, using standardized measure of breastfeeding difficulty. Exclusion: qualitative and purely observational studies, lacked operational definition of breastfeeding difficulty, lacked control/comparison group. We assessed risk of bias, summarized study quality and results, and conducted meta-analysis using random effects modelling.

RESULTS: Six studies on tongue tie division were included (4 randomized, 2 non-randomized). Meta-analysis of standardized mean differences in breastfeeding difficulty scores in four studies showed statistically significant differences in favour of frenotomy (Pooled SMD +2.12, CI:(0.17-4.08)p=0.03). Similarly, a statistically significant difference in favour of frenotomy was observed for pain (Pooled SMD -1.68, 95% CI:(-2.87- -0.48).

CONCLUSION: Results support that infant frenotomy is effective for improving standardized scores on breastfeeding difficulty and maternal pain scales and could improve breastfeeding outcomes.

PMID:35150472 | DOI:10.1111/apa.16289

Bosn J Basic Med Sci. 2022 Feb 10. doi: 10.17305/bjbms.2021.6841. Online ahead of print.

ABSTRACT

In dentistry, indirect diagnostic methods such as electrical sensibility testing and pulse oximetry are used to assess the status of the pulp. Our study aimed to determine the correlation between hemoglobin oxygen saturation and vascular volume density (Vvasc). We also wanted to examine an electrical sensibility test and the volume density of myelinated nerve fibers (Vnerv). Twenty-six intact permanent premolars were included in the study. For histological analysis, the pulp tissue was stained with hematoxylin-eosin and immunohistochemically for von Willebrand factor and S100 to detect blood vessels and myelinated nerve fibers, respectively. The stereological analysis was used to determine the Vvasc and Vnerv. Statistical analysis was done using the Pearson correlation test and Welch’s ANOVA test. Histological analysis showed that the pulp tissue was strongly vascularized and innervated. A significant positive correlation was found between Vvasc and hemoglobin oxygen saturation levels (p=0.030). A significant negative correlation was found between Vnerv and the lowest electrical voltage that patient felt (p=0.033). According to the maturity of the dental apex, teeth were divided into a group with open (N=6, OA group) and closed apex (N=20, CA group). We found that pulps in the CA group had higher Vnerv than the OA group (p=0.037). In contrast, there were no significant differences in Vvasc of the pulp tissue (p=0.059), oxygen saturation (p=0.907), or electrical voltage (p=0.113) between both groups. We can conclude that the measurement of pulse oximetry and electrical sensibility test reflect the morphology of healthy pulp tissue independently of the maturity of the dental apex.

PMID:35150478 | DOI:10.17305/bjbms.2021.6841