Tag: pubmed

Int J Sports Physiol Perform. 2021 Mar 23:1-8. doi: 10.1123/ijspp.2020-0264. Online ahead of print.

ABSTRACT

PURPOSE: To analyze the acute effect of photobiomodulation (PBM) on swimming critical velocity (CV).

METHODS: A total of 15 male federated swimmers (20.9 [2.4] y old) participated in this study. Three sets of front crawl were performed at distances of 100, 200, and 400 m to determine the CV under 3 experimental conditions: PBM (420 J), placebo (PLA), and control (C) in this randomized, crossover, double-blind, and placebo-controlled study. One-way analysis of variance for repeated measurements was used for statistical analyses.

RESULTS: The results showed that the prior application of PBM did not have ergogenic effects on CV and front crawl swimming performance: CV (PBM = 1.15 [0.15]; PLA = 1.20 [0.25]; C = 1.15 [0.14] m·s-1), swim time (ST) 100 m (PBM = 65.5 [6.3]; PLA = 65.2 [5.6]; C = 66.0 [5.9] s), ST 200 m (PBM = 148.5 [17.9]; PLA = 149.4 [16.4]; C = 150.1 [17.9] s), and ST 400 m (PBM = 327.7 [38.2]; PLA = 321.6 [47.7]; C = 329.5 [41.2] s).

CONCLUSIONS: A PBM application prior to front crawl swimming test did not significantly modify the CV, ST, physiological factors of metabolic fatigue, perceptual, and front crawl stroke efficiency parameters in competition swimmers covering distances of 100, 200, and 400 m.

PMID:33761459 | DOI:10.1123/ijspp.2020-0264

Food Chem. 2021 Mar 9;354:129529. doi: 10.1016/j.foodchem.2021.129529. Online ahead of print.

ABSTRACT

Approximately two-thirds of US infants receive infant formula (IF) as a primary or sole nutritional source during the first six months of life. IF is available in a variety of commercial presentations; from a manufacturing standpoint, they can be categorized as powder- (PIF) or liquid- (LIF) based formulations. Thirty commercial IFs were analyzed in their oxidative and non-oxidative lipid profiles. We identified 7-ketocholesterol – a major end-product of cholesterol oxidation – as a potential biomarker of IF manufacturing. The statistical analysis allowed a re-classification of IF based on their metabolomic fingerprint, resulting in three groups assigned with low-to-high oxidative status. Finally, we modeled the dietary intake of cholesterol, sterols, and 7-ketocholesterol in the first year of life. The database provided in this study will be instrumental for scientists interested in infant nutrition, to establish bases for epidemiological studies aimed to find connections between nutrition and diet-associated diseases, such as sitosterolemia.

PMID:33761334 | DOI:10.1016/j.foodchem.2021.129529

J Exp Child Psychol. 2021 Mar 21;207:105128. doi: 10.1016/j.jecp.2021.105128. Online ahead of print.

ABSTRACT

Preschool children engage in flattery behaviors, including expressing opinions toward other people or objects that-although favorable-are not truly held. Research shows that in the following years, the number and complexity of motives underlying such insincere behavior increase. The current study focused on children’s overt behavior, examining two aspects of the development of false praise-telling: individual stability and group-level discontinuity. Using an art-rating task, a total of 164 children aged 5 to 7 years were tested at three points in time (T1/2/3): M_T1 age = 5.66 years, SD = 0.1; M_T2 age = 6.65 years, SD = 0.16; M_T3 age = 7.61 years, SD = 0.14. The results show that, having become capable of giving false praise in politeness settings at 5.5 years of age, children continue to flatter others in this way at later ages, indicating that false praise-telling is an individually stable characteristic. In addition, a statistically significant increase in the proportion of false praise-telling to non-lying behavior in children over the 2-year study period was observed. This indicates that the discontinuity, namely the growth in children’s flattery behavior, occurs from 5 to 7 years of age. The findings are discussed with respect to the diverse factors that might underlie and affect children’s tendency to praise others falsely in politeness settings.

PMID:33761405 | DOI:10.1016/j.jecp.2021.105128

J Clin Virol. 2021 Mar 16;137:104795. doi: 10.1016/j.jcv.2021.104795. Online ahead of print.

ABSTRACT

BACKGROUND: Since the worldwide spread of SARS-CoV-2, different European countries reacted with temporary national lockdowns with the aim to limit the virus transmission in the population. Also Austria started a lockdown of public life in March 2020.

OBJECTIVES: In this study we investigated whether the circulation of different respiratory virus infections in Austria, as assessed by the established respiratory virus surveillance system, is affected by these measures as well and may reflect the success of the lockdown in limiting respiratory virus transmission.

STUDY DESIGN: Sentinel data obtained for influenza virus, respiratory syncytial virus, human metapneumovirus and rhinovirus cases were analyzed and compared between the season 2019/2020 and the five previous seasons.

RESULTS: We observed a rapid and statistically significant reduction of cumulative cases for all these viruses within short time after the lockdown in March 2020, compared to previous seasons (each p < 0.001). Also, sentinel screening for SARS-CoV-2 infections was performed and a decrease of SARS-CoV-2 was seen after the lockdown. While for the seasonally occurring viruses as influenza, respiratory syncytial virus or human metapneumovirus the lockdown led to the end of the annual epidemics, a re-increase of rhinovirus infections was observed after liberalization of numerous lockdown measures.

CONCLUSIONS: Our data provide evidence that occurrence of different respiratory virus infections reflect not only the efficiency of lockdown measures taken against SARS-CoV-2 but it shows also the effects of lockdown releases on the transmission of respiratory viruses.

PMID:33761423 | DOI:10.1016/j.jcv.2021.104795

Int J Law Psychiatry. 2021 Mar 21;76:101684. doi: 10.1016/j.ijlp.2021.101684. Online ahead of print.

ABSTRACT

Clinical impressions suggest that forensic patients in Belgium have more complex needs regarding care and risk in recent years than before. In this article, we analyzed psychometric data regarding patients’ symptoms, risk estimates, antisocial personality traits, and functional capabilities over a 10-year span in a medium-security unit for rehabilitation of forensic patients. Data from a total of 129 patients with a main diagnosis of psychosis were analyzed. Results confirmed that patients had higher risk assessment estimates, more psychopathic/antisocial personality traits, and lower cognitive and functional capabilities. The average psychotic symptom levels and protective factors did not statistically change over the ten-year period. The changes are thought to be due to a new forensic law and the creation of new high- and medium-risk beds.

PMID:33761440 | DOI:10.1016/j.ijlp.2021.101684

Appl Neuropsychol Adult. 2021 Mar 24:1-8. doi: 10.1080/23279095.2021.1890596. Online ahead of print.

ABSTRACT

The Trail Making Test (TMT) is a popular measure of cognitive functioning, especially processing speed and cognitive flexibility. This study aims to provide normative data for the Slovak adult population. The secondary aim is to test the convergent validity by examining relationships of direct and derived indices to other neuropsychological measures. A sample of 487 healthy adults undertook neuropsychological testing. The relationships of TMT scores to demographic variables and other neuropsychological measures were tested. Age was positively correlated with TMT-A (r = 0.444, p < .01), TMT-B (r = 0.426, p < .01), and the B-A index (r = 0.317, p < .01). Years of education were negatively correlated with TMT-B (r = -0.183, p < .01), B-A difference (r = -0.188, p < .01) and B/A ratio (r = -0.119, p < .01). There were no statistically significant differences in performance based on gender. The test scores were correlated with other measures of processing speed and executive functions. Presented normative data are stratified into 7 age categories. For more accurate interpretation, regression equations were calculated to take years of education into account. TMT-A and B performance, as well as B-A difference score, must be interpreted in relation to age, while education can provide additional information. The B/A ratio is independent from age but should be also corrected for educational level.

PMID:33761301 | DOI:10.1080/23279095.2021.1890596

Surg Infect (Larchmt). 2021 Mar 23. doi: 10.1089/sur.2020.432. Online ahead of print.

ABSTRACT

Background: There has been much debate as to the importance of mechanical bowel preparation (MBP) and oral antibiotic agents (OAB) prior to elective colorectal surgery over the past two decades. There is no consensus between international guidelines. Methods: The Australia and New Zealand Mechanical Bowel Preparation and Oral Antibiotics (ANZ-MBP-OAB) questionnaire was distributed to colorectal surgeons after institutional board approval assessing specialist attitudes toward 18 enhanced recovery after surgery (ERAS) interventions. Data were analyzed using a rating scale and graded response model in item response theory (IRT) on Stata MP, version 15 (StataCorp LP, College Station, TX). Specialist attitudes toward the effectiveness of MBP and OAB strategies in providing better short-term outcomes was ranked alongside other ERAS interventions. This was followed by specific questions examining current practice, perspectives, and trends. Results: Ninety-five of 300 (31.7%) colorectal surgeons in Australia and New Zealand participated in the survey. Statistical modeling was achieved in 13 ERAS interventions. Compared with other ERAS interventions, the use of MBP with OAB and MBP alone ranked nine of 13 and 10 of 13, respectively, in order of effectiveness in providing better short-term outcomes after colorectal surgery. Oral antibiotic agents alone was not considered effective. Mechanical bowel preparation with OAB was considered to be the best strategy in both colon (37%) and rectal surgery (48%) but current practice varied substantially from perspective. Mechanical bowel preparation alone was strongly favored in rectal surgery (81%) with only 14% using MBP with OAB. In colon surgery, only 10% used MBP with OAB, with MBP alone (45%) and no preparation (45%) being equally the most commonly used strategies. Conclusions: Among Australian and New Zealand colorectal surgeons, MBP with OAB was considered the best bowel preparation strategy. However, despite an awareness of its benefits, MBP with OAB has yet to be widely adopted into clinical practice or guidelines in Australia and New Zealand.

PMID:33761307 | DOI:10.1089/sur.2020.432

Clin Pharmacol Drug Dev. 2021 Mar 24. doi: 10.1002/cpdd.931. Online ahead of print.

ABSTRACT

Studies on the effects of memantine on QT prolongation have yielded conflicting results. For a long time, memantine was reported to be a safe drug without QT prolongation; however, several case studies have reported memantine-induced QT prolongation in Alzheimer’s patients. This study evaluated the relationship between memantine blood levels, and QT interval changes. Over a 2-week period, we orally administered 20 mg of memantine daily to achieve a steady state in 57 healthy Korean subjects. We measured and analyzed the QT interval and blood memantine concentrations simultaneously before and after treatment, as well as 2 weeks after the last dosing. Correlation analysis was done between blood memantine level and QT interval. No serious adverse events occurred during the study period. Repeated dosing of memantine did not show clinically significant QT interval changes after treatment. Regression analysis was performed based on the results; there was no statistical association between memantine blood level and QT prolongation. In conclusion, the results of the present study demonstrated no clinically significant changes in the QT interval with therapeutic blood levels of memantine.

PMID:33761171 | DOI:10.1002/cpdd.931

Health Soc Care Community. 2021 Mar 24. doi: 10.1111/hsc.13363. Online ahead of print.

ABSTRACT

Recently, discussion of the potential of health literacy (HL) for health promotion has increased; however, clear evidence illuminating the relationship between adolescents’ HL and their physical activity (PA) remains scarce. This study aimed to assess the association between adolescents’ HL and leisure time PA. A representative cross-sectional study was conducted with 2,369 Lithuanian adolescents aged 13-16 years. A self-reported questionnaire gathered information regarding HL, leisure time PA, and other confounders (gender, age, family affluence and parents’ exercise). Descriptive statistics and the probabilities of being physically active were estimated using logistic regression. The results revealed that almost 60% of the participants were not sufficiently physically active. Having moderate or high levels of HL was positively associated with leisure time PA. Additionally, being male, belonging to a more affluent family, and having a father who exercise were significant predictors of adolescents’ leisure time PA. This study revealed that moderate and high HL positively related to leisure time PA among Lithuanian adolescents. The study results highlighted the importance of encouraging schoolchildren’s PA and including HL promotion in a school curriculum.

PMID:33761177 | DOI:10.1111/hsc.13363

J Food Sci. 2021 Mar 24. doi: 10.1111/1750-3841.15685. Online ahead of print.

ABSTRACT

This study aims at investigating whether the livestock, lactation stage, or geographical origin of specialty milk in China could be classified by the elemental contents. Samples of goat, buffalo, and yak milk were collected from main production provinces in China and the contents of nine elements in milk from different livestock, regions, and lactation stages were determined. Statistical analysis indicated that the contents of Mn, Cu, As, Se, Cs, and Mo in mature milk were significantly different between the three livestock (p < 0.05). The trends of Mn and Cs contents of the goat milk and buffalo milk increased first and then decreased gradually during lactation. The contents of Se, Cs, Ba, and Mo in mature milk of three livestock were significantly different between the three regions (p < 0.05). The result of linear discriminant analysis (LDA) and partial least squares discrimination analysis (PLS-DA) showed that the total correct classification rates in different livestock for mature milk reached 86.7 and 90%. For goat milk, the total correct classification rates of different lactations and regions reached 88.9 and 77.8% for LDA (100 and 87.5% for PLS-DA), and followed by yak milk of different regions which achieved 88.9% for LDA (88.9% for PLS-DA). In summary, the microelements in milk showed a significant correlation with livestock, region, and lactation of goat, buffalo, and yak milk. The elemental fingerprints combined with the LDA could be potential for classifying the livestock, lactation stage, and geographical origin of milk. PRACTICAL APPLICATION: According to study the contents of miroelements in milk from different livestock, regions, and lactation stages, provide evidence and support for classifying the livestock, lactation stage, and geographical origin of milk.

PMID:33761138 | DOI:10.1111/1750-3841.15685