Tag: pubmed

Indian J Dent Res. 2021 Apr-Jun;32(2):192-198. doi: 10.4103/ijdr.IJDR_943_20.

ABSTRACT

CONTEXT: Oral Lichen planus (OLP) is a chronic, debilitating, immune-mediated disease whose management is considered a challenge in medical science.

AIMS: To quantitatively evaluate the effect of administration of enteral hydroxychloroquine (HCQS) as a monotherapy for six months on the extent and severity of erosive OLP using reticular score, erythema score and ulcerative score (REU score), and to subjectively evaluate the success of HCQS as a therapeutic drug for OLP-e using Tel Aviv-San Francisco Scale, visual analogue scale (VAS) and severity of burning sensation (BURN score).

SETTINGS AND DESIGN: Prospective clinical trial.

METHODS AND MATERIAL: A total of 45 subjects received 200 mg of HCQS bid for six months. REU, VAS, BURN scores and Tel Aviv-San Francisco Scale readings were taken at the beginning of the study (baseline) and three- and six-month intervals post administration of enteral HCQS. Subjects were examined for any adverse drug outcomes for one year after the cessation of enteric HCQS therapy. Data were analysed with SPSS version 25.

RESULTS: There was a stark reduction in REU, VAS and BURN scores during the study period, with a statistically significant reduction (P < 0.05) seen at three- and six-month time intervals as compared to baseline. Further, the mean of change in R, E and U scores showed a statistically significant difference, with the highest reduction seen at baseline to six-month time interval. The Tel Aviv-San Francisco Scale showed 70%-100% remission in disease in more than 70% of subjects.

CONCLUSIONS: Enteral HCQS can be considered a viable treatment option for the enigma that is erosive OLP.

PMID:34810388 | DOI:10.4103/ijdr.IJDR_943_20

Indian J Dent Res. 2021 Apr-Jun;32(2):206-210. doi: 10.4103/ijdr.ijdr_483_21.

ABSTRACT

CONTEXT: The Corona Virus Disease 2019 (COVID-19) is a contagious disease caused by the novel Coronavirus (2019-nCoV) and was declared a pandemic disease by the World Health Organization (WHO) in March 2020. The nasopharyngeal and the oropharyngeal swabs are being taken during the screening procedure. However, the virus is also present in the oral bio-fluid and hence it could be a potential tool for screening COVID-19 cases.

AIM: The aim of the present study was to test the accuracy of whole saliva as a diagnostic specimen in COVID-19.

SETTINGS AND DESIGN: This cross-sectional, analytical study was conducted on out-patients visiting the COVID-19 hospital.

METHODS AND MATERIAL: The whole saliva and the nasopharyngeal/oropharyngeal samples from 309 COVID-19 suspected patients were collected and subjected to RT-PCR analysis.

STATISTICAL ANALYSIS USED: The paired t test was used to compare the measured variables (C_T values) between the saliva and the swab samples. The positive predictive value (PPV), negative predictive value (NPV), the sensitivity, and the specificity of the tests were calculated for the saliva sample.

RESULTS: The saliva and swab results revealed a similar result (ties) in 86.73% of the samples. The sensitivity and the specificity between the swab and saliva samples were 40% and 96.85%, respectively. The positive predictive value of the saliva sample was 73.3%.

CONCLUSIONS: The sensitivity of whole saliva when compared to the swab samples is low. Large sample studies are needed to validate the role of saliva as a diagnostic tool in COVID-19.

PMID:34810390 | DOI:10.4103/ijdr.ijdr_483_21

Indian J Dent Res. 2021 Apr-Jun;32(2):167-173. doi: 10.4103/ijdr.IJDR_637_18.

ABSTRACT

CONTEXT: Smile aesthetics is one of the major goals to be achieved after orthodontic mechanotherapy as it visibly displays the results of orthodontic treatment. Although orthodontic retainers aid in maintaining post-treatment occlusion, soft tissue function and aesthetics, appropriate knowledge of smile changes with age can help orthodontists to obtain stable and aesthetically appealing treatment results.

AIM: To assess and quantify soft tissue changes in the upper lip in vertical dimension at both repose and maximum smiling and to evaluate changes occurring with the smile index and upper lip with age and sex in subjects of Indian origin.

SETTINGS: Department of Orthodontics and Dentofacial Orthopaedics, Army College of Dental Sciences, Secunderabad, Telangana, India.

DESIGN: Observational study.

METHODS AND MATERIALS: A total of 160 volunteers (80 males and 80 females) selected and were divided into 4 groups according to age and were further divided into 2 sub-groups according to gender. Thirteen measurements of relaxed and smiling upper lip were taken with a calibrated metal ruler and divider directly on the subjects.

STATISTICAL ANALYSIS USED: Analysis of variance (ANOVA) was done followed by post hoc test to determine which groups were significant from others. Levene’s test was done to assess equality of variance and t-test for equality of means was done.

RESULTS: Statistically significant results were obtained in between groups and sub-groups for parameters like smile index, upper lip elevation while smiling and smile pattern in males and females changing with increase in age.

CONCLUSIONS: High smile patterns with more vertical smile are more common among females and low smile patterns are more common among males. With age, the smile tends to be more horizontal in both genders.

PMID:34810384 | DOI:10.4103/ijdr.IJDR_637_18

Indian J Dent Res. 2021 Apr-Jun;32(2):174-180. doi: 10.4103/ijdr.IJDR_1050_20.

ABSTRACT

BACKGROUND: The lower canine to canine retainer is one of the most commonly used retention appliance.

OBJECTIVE: Compare and assess the clinical efficiency and oral hygiene maintenance with 2 retainers: flexible spiral wire and ceramic interlocking bonded.

SETTING AND SAMPLE POPULATION: Orthodontic department of a dental college.

PARTICIPANTS, STUDY DESIGN AND METHODS: Prospective randomized controlled trial that involved 40 patients who had completed orthodontic treatment and were randomly allotted to either group: flexible spiral wire (FSW) or ceramic interlocking retainers. Allocation ratio was 1:1.

ELIGIBILITY CRITERIA: Completed fixed orthodontic treatment with an acceptable treatment result.

MAIN OUTCOMES: Oral hygiene was assessed at 3 (T1) and 6 (T2) months intervals after debonding using Gingival and Plaque index. The contact point displacement was assessed using 3D model superimposition and bonded retainer failure was noted.

RANDOMIZATION AND BLINDING: Computer-generated random allocation, only data analyzer was blinded.

STATISTICS: Data normality was tested using the Shapiro-Wilk and Q-Q plot. Mixed model analysis was used to assess differences between the two groups for the above-mentioned parameters. The failure rate of the retainer was calculated by the Chi-Square test.

RESULTS: Only the plaque index score was significantly greater in the FSW group and showed a statistically significant difference (P < 0.05), rest of the parameters showed no statistically significant difference over the specified time points, although a mild increase in relapse was noted in both groups No serious harms were reported.

CONCLUSION: Both retainers seem to be effective in maintaining the treatment results however the FSW seems to accumulate more plaque over a given period of time thereby mandating proper hygiene maintenance and follow-up.

PMID:34810385 | DOI:10.4103/ijdr.IJDR_1050_20

Indian J Dent Res. 2021 Apr-Jun;32(2):158-161. doi: 10.4103/ijdr.ijdr_5_21.

ABSTRACT

CONTEXT: Most often, young children with early childhood caries (ECC) may need oral rehabilitation under general anaesthesia (GA) as treatment cannot be done chairside. A procedure under GA can be traumatic and stressful for both the parents and the children. Hence, it becomes necessary to understand the parents’ opinions and address their concerns to provide better treatment. Aims: This qualitative study was conducted to explore the parental issues and concerns for their children treated under GA for ECC. Qualitative research approach was used so that it would enable us to address these issues better and prepare parents by counselling them in advance.

SETTINGS AND DESIGN: An in-depth interview was conducted with the parents of children who underwent oral rehabilitation under GA for ECC in the M.S. Ramaiah Memorial Hospital, admitted under the Department of Pedodontics and Preventive Dentistry.

PARTICIPANTS AND METHODS: Data were audio-recorded and transcribed.

STATISTICAL ANALYSIS USED: Data collected were analysed using thematic analysis. Results: The themes derived were ‘Concerns and Issues of GA Procedures and Improved Oral-health-related Quality of Life’.

CONCLUSIONS: The parents of children who underwent oral rehabilitation under GA initially had a few concerns and were reluctant about the procedure but were happy with the improvement post-operatively.

PMID:34810382 | DOI:10.4103/ijdr.ijdr_5_21

Indian J Dent Res. 2021 Apr-Jun;32(2):162-166. doi: 10.4103/ijdr.IJDR_677_19.

ABSTRACT

AIMS: To determine the applicability of Moyer’s probability tables in North Indian population of 16-18 year olds and to formulate a new regression equation for the same group of population.

SETTING AND DESIGN: Evaluative Study.

METHODS AND MATERIAL: 1000 children aged 16-18 years were selected as sample for the measurement of mesiodistal widths of permanent mandibular incisors, maxillary and mandibular canines and premolars using study models. The recorded values were then subjected to statistical analysis.

STATISTICAL ANALYSIS USED: Software Package for Social Sciences (SPSS) software version 22.0.

RESULTS: The actual widths of the canine and premolars showed highly significant differences in maxilla and in mandible (P < 0.001), compared to widths predicted by Moyer’s probability table at 75^th percentile.

CONCLUSION: Moyer’s mixed dentition analysis was not an accurate method for prediction in North Indian population as it showed overestimation of tooth sizes. Hence, new regression equation has been formulated for the same.

PMID:34810383 | DOI:10.4103/ijdr.IJDR_677_19

Indian J Dent Res. 2021 Apr-Jun;32(2):147-152. doi: 10.4103/ijdr.IJDR_676_18.

ABSTRACT

INTRODUCTION: Parents’ infant and early childhood oral health knowledge is of paramount importance, because oral health behaviours are the exclusive domain of parents during the early years of life. Studies exploring the association between mother’s behaviour, oral health literacy and children’s oral health outcomes are scarce.

AIM: To evaluate the association between mother’s behaviour, oral health literacy and children’s dental caries experience.

MATERIALS AND METHODS: A cross-sectional study was conducted among one hundred pre-school children aged 2-6 years and their mothers from pre-schools in Bangalore, India. Data regarding their demographics, mother’s knowledge, attitude and practice (KAP) was collected through a questionnaire. Mother’s oral health literacy was assessed with Rapid Estimate of Adult Literacy in Dentistry-30 (REALD-30) scale. Caries experience of the children was recorded using Decayed Missing Filled Teeth (DMFT) Index. Data was entered into excel sheet and analysed using statistical package for SPSS 22.0.

RESULTS: : The mean KAP, REALD-30 and DMFT scores were 13.17 ± 4.57, 17.68 ± 5.85, 2.61 ± 2.21, respectively. In this study, REALD-30 score negatively correlated with DMFT score and positively correlated with KAP score. In a linear regression, KAP and REALD-30 scores showed a highly significant association with dental caries.

CONCLUSION: Mother’s behaviour and oral health literacy influenced caries experience of the children. Therefore, improving the behaviour and oral health literacy of the mothers is the key to influence child’s oral health.

PMID:34810380 | DOI:10.4103/ijdr.IJDR_676_18

J Indian Prosthodont Soc. 2021 Oct-Dec;21(4):425-429. doi: 10.4103/jips.jips_135_21.

ABSTRACT

AIMS: To evaluate the flexural properties of computer-aided design-computer-aided manufacturing (CAD-CAM) milled posts fabricated from the experimental fibre-reinforced composite disks in different fibre direction, and to compare the flexural properties of the CAD-CAM milled posts to those of commercial prefabricated posts, RelyX and FRC PostecPlus.

SETTINGS AND DESIGN: In vitro comparative study.

MATERIALS AND METHODS: E-glass fibre was used to fabricate the CAD-CAM composite disks. The fibres were prepared in unidirectional and multidirectional arrangements into the epoxy resin, at 70% by weight. The disk was milled by the Cerec InLab CAD-CAM system to fabricate a post. Ten posts for each type of disk were prepared. Two types of commercial fibre posts, RelyX fibre post, and FRC PostecPlus were used as control. The three-point bending test was performed.

STATISTICAL ANALYSIS USED: The data were analysed using one-way ANOVA and Game-Howell post-hoc test.

RESULTS: The results indicated that both commercial fibre posts had the highest flexural strength and flexural modulus. The unidirectional experimental post yielded significantly lower values in both flexural strengths (739.1 ± 24.1 MPa) and flexural modulus (21.0 ± 3.5 GPa) compared to the control posts, while the multidirectional experimental posts had extremely low flexural strength and flexural modulus.

CONCLUSIONS: The direction of the fibres significantly influenced the mechanical properties of the posts. The experimental unidirectional fibre-reinforced composite disk showed the potential to be used as a CAD-CAM disk for post and core fabrication.

PMID:34810372 | DOI:10.4103/jips.jips_135_21

Indian J Dent Res. 2021 Apr-Jun;32(2):140-146. doi: 10.4103/ijdr.IJDR_508_18.

ABSTRACT

BACKGROUND: The disease profile of the world is changing at an astonishingly fast rate. It is essential that the impending nature of chronic disease is recognized and acted on urgently. India leads the world with the largest number of diabetics earning the dubious distinction of being termed the “diabetic capital” of the world.

AIM: To assess and compare the oral health status and related oral health risk factors among diabetic patients in Hyderabad and Secunderabad.

SETTINGS: A cross sectional study was carried out in various diagnostic centers among 801 patients aged 30 years and above.

METHODS AND MATERIALS: Oral health status and self-assessed data on related oral risk factors were measured using modified World Health Organization (WHO) assessment form and oral health questionnaire for adults 2013.

STATISTICAL ANALYSIS: Comparison of mean scores of the variables based on gender was assessed using ANOVA. Statistical significance was set at p < 0.05.

RESULTS: Females had higher proportion of untreated caries (362; 85%) and DMFT (Decayed, Missing and Filled Teeth; 375; 88%) compared to males. On the basis of loss of attachment, the mean number of sextants with no loss of attachment was mostly noted among female subjects.

CONCLUSION: In the present study, though gingivitis was seen in higher percentage (82%), the presence of periodontal disease was relatively low (68.3%). It can be concluded that diabetic subjects may have poor oral health.

PMID:34810379 | DOI:10.4103/ijdr.IJDR_508_18

J Indian Prosthodont Soc. 2021 Oct-Dec;21(4):412-419. doi: 10.4103/jips.jips_199_21.

ABSTRACT

AIM: The aim of this study is to assess the surface roughness and shear bond characteristics of pol-ether-ether-ketone after different surface treatments.

SETTING AND DESIGN: An in vitro, prospective.

MATERIALS AND METHODS: One hundred and twenty disc-shaped samples of 10 mm diameter and 2 mm thickness were milled and subjected to following surface treatments: 110 μm alumina particles, 98% concentrated sulfuric acid, and 10-20 μm synthetic diamond particles. Surface characteristics of treated sample were studied under SEM with ×500 and ×1000 magnification. Shear bond strength (SBS) with composite resin discs embedded in acrylic blocks after luting with self-etch resin cement and resin-modified glass ionomer cement (RMGIC) was evaluated using the universal testing machine (Instron®, Massachusetts U. S. A).

STATISTICAL ANALYSIS USED: The data collected were evaluated using the Analysis of variance and Tukey’s honest significant difference post hoc test.

RESULTS: Highest SBS and SR were noted with self-etch resin cement in the given order: 98% sulfuric acid (2.106 ± 0.186 μm), followed by alumina particles (1.706 ± 0.160 μm) and synthetic diamond particles (1.101 ± 0.167 μm).

CONCLUSION: The SBS of self-etch resin cement was higher compared to RMGIC for all three surface treatments done on test samples. Hundred percent samples treated by all three surface treatment methods showed mixed type of failure.

PMID:34810370 | DOI:10.4103/jips.jips_199_21