Tag: statistics

J Cosmet Dermatol. 2021 May 22. doi: 10.1111/jocd.14246. Online ahead of print.

ABSTRACT

BACKGROUND: Sensitive skin is subjective cutaneous hyperreactivity to environmental factors. Demodicosis is a skin disorder caused by Demodex.There may be a link between demodicosis and sensitive skin.

AIM: This study aimed to examine facial Demodex density and other factors associated with sensitive skin in patients.

METHODS AND METHODS: A total of 349 randomly selected patients who presented to the dermatology department. The research data were collected using a questionnaire form that included the participants’ sociodemographic and lifestyle characteristics, a sensitive skin questionnaire, the Dermatology Life Quality Index (DLQI), and European Health Interview Survey (EHIS). Patients underwent standardized superficial skin surface biopsy of 4 areas of the face. D. folliculorum count greater than 5 mites/cm² was considered positive.

RESULTS: In relation to Demodex, there was an increase in skin sensitivity with higher Demodex density (p =0,04). There was a statistically significant, weak positive correlation between skin sensitivity and DLQI score (r=0.33, p=0.00) and there was also a significant but very weak negative correlation between skin sensitivity and EUROHIS (r=-0.164, p=0.002). Skin sensitivity was more common in patients with a concomitant dermatological disease (p=0.01) and increased with more frequent cosmetic use (p=0.00).

CONCLUSION: Alongside other risk factors, for the patients presenting with complaints of sensitive skin, investigating Demodex population density may help alleviate sensitive skin symptoms with appropriate therapies and preventive measures.

PMID:34021963 | DOI:10.1111/jocd.14246

PM R. 2021 May 22. doi: 10.1002/pmrj.12645. Online ahead of print.

ABSTRACT

BACKGROUND: Rehabilitation outcomes of COVID-19 patients are unknown.

OBJECTIVE: The purpose of this study is to describe COVID-19 patients undergoing inpatient rehabilitation and their rehabilitation outcomes.

METHODS: Retrospective observational cohort study of all inpatients from a rehabilitation hospital between March 1 and September 30, 2020. Inclusion criteria are: ≥18 years of age and admission and discharge within the study time frame. The initial search yielded 920 patients; 896 met the inclusion criteria. Data was derived from the eRehabData database. Subjects were stratified by COVID-19 status and rehabilitation impairment. Data included age, gender, body mass index (BMI), length of stay (LOS), discharge location, and functional ability measures for self-care and mobility (FA-SC, FA-Mob). Descriptive statistics included age, BMI, gender, LOS, and discharge location. One-sample t-tests were used to assess the difference of age, BMI, LOS, FA-SC, FA-Mob, and FA efficiency between COVID-19+ and COVID-19- patients.

RESULTS: COVID-19+ patients were younger (59·4 years vs 62·9 years; t(894)= -2·05, p=0·04) with a higher mean BMI (32 vs 28; t(894)= 3·51, p<0·01) than COVID-19- patients. COVID-19+ patients had equivalent or superior improvements in FA-SC and FA-Mob, functional change efficiency, and LOS than COVID-19- patients. Comparing Medically Complex patients, those with COVID-19 had greater FA-SC and FA-Mob efficiencies than COVID-19- patients. COVID-19+ patients had similar rates of return to the community.

CONCLUSIONS: Patients with COVID-19 who meet the admission criteria for inpatient rehabilitation can benefit from inpatient rehabilitation similarly to their non-COVID-19 counterparts with similar rehabilitation-specific diagnoses. This article is protected by copyright. All rights reserved.

PMID:34021974 | DOI:10.1002/pmrj.12645

Chest. 2021 Apr;159(4):1677-1678. doi: 10.1016/j.chest.2020.11.029. Epub 2021 Apr 6.

NO ABSTRACT

PMID:34021997 | DOI:10.1016/j.chest.2020.11.029

J Nurs Manag. 2021 May 22. doi: 10.1111/jonm.13384. Online ahead of print.

ABSTRACT

BACKGROUND: There is a scarcity of literature assessing the impact of job engagement and satisfaction in the nurse’s caring behaviors. This study aim to identify how these factors affect the caring behaviours of nurses.

METHODS: This study used a cross-sectional design and employed self-report questionnaires. A total of 549 nurses from private and government hospitals participated in the survey conducted in the year 2019. Descriptive and inferential statistics were utilized to analyse the data.

RESULTS: Results revealed that the nurses display high caring behaviours and job engagement and moderate sense of satisfaction. Remarkably there are no profile variables significantly related to the nurse’s caring behaviors. Findings suggest that job engagement and satisfaction are significantly associated with the nurses’ caring behaviours.

CONCLUSION: Factors such as job engagement and satisfaction affect nurses caring behaviours.

IMPLICATIONS TO NURSING MANAGEMENT: Health organizations must provide strategies to increase job engagement and satisfaction of nurses to yield high caring behaviours, which is vital to the achievement of patient safety.

PMID:34021940 | DOI:10.1111/jonm.13384

Int J Clin Pract. 2021 May 22:e14384. doi: 10.1111/ijcp.14384. Online ahead of print.

ABSTRACT

BACKGROUND: We tend to find out whether BMI and weight have difference in the connection with the disease severity of AECOPD patients. Besides, we aim to explore the relationships between body fat (BF) and lean body mass (LBM) with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).

METHODS: Information like weight and body mass index (BMI) were recorded at hospital admission. BF and LBM were assessed using dual energy X-ray absorptiometry (DEXA). Logistic regression analysis, receiver operating characteristic (ROC) curves and other statistical analyses were performed.

RESULTS: Weight and BF + LBM showed significant linkages with the Global Initiative for Chronic Obstructive Lung Disease (GOLD) in multivariate logistic regression analysis (Model 3: OR = 0.932, p = 0.016; OR = 0.915, p = 0.006, respectively). And BMI did not show correlation with GOLD. In Stratification analysis, BF showed the predictive value for GOLD (AUC = 0.709, p = 0.004) while LBM showed the predictive ability for modified Medical Research Council scale (mMRC) (AUC = 0.761, p < 0.001).

CONCLUSION: BF + LBM and weight were better than BMI in the connection with the disease severity of AECOPD patients represtented by GOLD. BF and LBM may have different or even opposite effects on patients with AECOPD.

PMID:34021950 | DOI:10.1111/ijcp.14384

Hepatology. 2021 May 22. doi: 10.1002/hep.31916. Online ahead of print.

ABSTRACT

We read with great interests the study by Dr. John et al. In this retrospective study using national data on USA Veterans, multivariate competing risk analysis identified that male gender was independently associated with a higher risk of death/transplantation, and liver-related death/transplantation for patients with primary biliary cholangitis (PBC) and cirrhosis.

PMID:34021935 | DOI:10.1002/hep.31916

JPEN J Parenter Enteral Nutr. 2021 May 22. doi: 10.1002/jpen.2195. Online ahead of print.

ABSTRACT

INTRODUCTION: Hospital-acquired central line-associated bloodstream infections (CLABSI) are “never events” in U.S. healthcare. Efforts to eliminate CLABSI are critically important to children with intestinal failure (IF) who depend on long-term, daily use of a central venous catheter (CVC) and often undergo extended hospitalizations. They are also vital to the safety of any patient with a CVC. We sought to describe long-term outcomes of a multidisciplinary CLABSI elimination effort on a 24-bed medical-surgical unit caring for children with IF.

METHODS: Unit CLABSI events from 1/9/2012 to 4/16/2020 were evaluated in the context of multiple interventions aimed at preventing CLABSI; leveraging prospectively maintained clinical registries and National Healthcare Safety Network (NHSN) reporting data, patient and unit demographics, ethanol lock utilization, and unit CVC days. Interventions, including zinc oxide-based adhesive barriers, environmental cleaning, and simulation as part of staff education were developed utilizing consensus of hospital experts and Centers for Disease Control and Prevention guidelines with staff engagement. Descriptive statistics and tests of non-parametric data were employed for analysis.

RESULTS: Ninety-five patients with IF and 862 non-IF patients experienced a total of 1,629 admissions with 20,372 CVC days during the study period. Twelve hospital-acquired CLABSI events occurred, including 7 following NHSN definition change on 1/1/2015 (0.56 per 1,000 CVC days). Following the last unit CLABSI on 12/5/2016, there were 7,117 CVC days without CLABSI through study conclusion.

CONCLUSIONS: Use of described interventions in the context of an enhanced culture of collaborative care and ownership is associated with hospital-acquired CLABSI elimination. Success in a specific population translated to all other unit patients with a CVC. Findings suggest that CLABSI elimination is not the result of a single new product or practice but rather an approach that supports and empowers those most closely responsible for care of the patient and their CVC is key. This article is protected by copyright. All rights reserved.

PMID:34021937 | DOI:10.1002/jpen.2195

Mol Biol Rep. 2021 May 22. doi: 10.1007/s11033-021-06413-x. Online ahead of print.

ABSTRACT

The rhizosphere of a plant is an important interface for the plant-microbe interaction that plays a significant role in the uptake and removal of heavy metal from contaminated sites. Eichhornia crassipes is a free-floating macrophyte and a well-known metal hyperaccumulator. It is a promising plant, which harbors a diverse microbial community in its rhizosphere. Therefore it is hypothesized that it can be a good habitat for microorganisms that supports plant growth and increases its phytoremediation potential. The rhizospheric DNA was extracted from the procured plant samples. The library was prepared and sequenced using the Illumina platform. 16S rRNA data from the Next Generation Sequencing (NGS) platform was analyzed using the QIIME software package. Alpha diversity was estimated from statistical indices i.e. Shannon index, Chao1 index, and observed species. The rarefaction plots, rank abundance curve, krona graph, and heat map were generated to study the rhizospheric community in detail. Metagenome consisted of 225,408 flash reads, 185,008 non-chimeric sequences with 17,578 Operational Taxonomic Units (OTU’s), and 4622 OTU’s without singletons. The data of present study are available at NCBI Bioproject (PRJNA631882). The taxonomic analysis of OTU’s showed that the sequences belonged to major Phyla revealing the dominance of Proteobacteria, Bacteroidetes, Cyanobacteria, and Verrucomicrobia. The most abundant Genera in the sampled rhizosphere recorded were Thiothrix and Flavobacterium.

PMID:34021896 | DOI:10.1007/s11033-021-06413-x

Acta Ortop Mex. 2020 Nov-Dec;34(6):388-398.

ABSTRACT

INTRODUCTION: A comparative clinical study has been conducted on patients involved using lateral intersomatic arthrodesis for the treatment of adjacent segment disease using titanium and PEEK intersomatic devices.

MATERIAL AND METHODS: Clinical (EVA and oswestry disability index ODI) and radiological (alignment and fusion), complications (major and minor) and quality of life (EQ5D) of 32 patients intervened from September 2015 to September 2018 have been analyzed and compared, with an average follow-up of 25 months (46-18). The average age in surgery was 66 years (39-89) and 68% of patients were women.

RESULTS: The most common segment involved was L3-L4 (62%) right retroperitoneal approach 86%. Lumbar EVA improved from 6.2 ± 2.12 to 4.1 ± 1.71 (p = 0.028). The LEG EVA descended from 5.3 ± 2.26 to 1.9 ± 1.58 (p = 0.02). The ODI scales improved from 50.2 ± 18.9 to 33.3 ± 10.2 (p = 0.025) and the EQ5D went from 0.52 to 0.73 (p = 0.039) with no statistically significant differences between the groups (ODI p = 0.18, EQ5D p = 0.293). Radiologically increased intervertebral height, lumbar and segmental lordosis, decreased Cobb’s angle and the overall melting rate was 84.3% (88% Ti/82% PEEK), with no differences between the groups.

CONCLUSION: Lateral lumbar interbody fusion is an effective method for treating adjacent segment disease with clinical-radiological results and literature-like complications. No differences have been found between Ti and PEEK implants.

PMID:34020519

Acta Ortop Mex. 2020 Nov-Dec;34(6):226-432.

ABSTRACT

INTRODUCTION: Intraarticular distal radius fractures are a therapeutic challenge for the orthopedist surgeon there are studies that support the use of fluoroscopy, and others promote arthroscopy, with this work we try to summarize the evidence, to determine whether arthroscopic assistance provides additional benefits to avoid joint incongruities compared to results obtained under fluoroscopic assistance.

MATERIAL AND METHODS: Systematic search for prospective, retrospective, cohort, follow-up, clinical trials on PubMed, MEDLINE, Scopus, Scielo, Embase, Google Scholar and other national sources, including as keywords the terms: “intra-articular distal radius fracture”, “wrist arthroscopy”, “arthroscopy”, “fluoroscopy”. The average values and standard offsets for each characteristic, obtained from the selected works, were analyzed using descriptive statistics and illustrative graphs.

RESULTS: 463 patients (256 women and 207 men) were evaluated, with an average age of 48.29 years and range from 39 to 64 years. The two treatments (A and F) were homogeneous in terms of the age of the patients reporting (p = 0.5820) and the average follow-up time (p = 0.9597). Only the ulnar deviation and DASH score, for which the arthroscopy group performed best, in the remaining variables the differences were not significant.

CONCLUSION: The evidence available to date is conflicting, and does not allow recommendations to be made for or against these interventions, finding other factors that could influence decision-making.

PMID:34020525