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Nevin Manimala Statistics

Diverse Care Needs Assessment for Older Adults in China: A Latent Profile Analysis Study

Public Health Nurs. 2025 Jan 22. doi: 10.1111/phn.13539. Online ahead of print.

ABSTRACT

BACKGROUND: Grasping the nuanced needs of older adults is paramount for the efficacious provision of day-care services. Our study sought to identify the demand patterns for day-care services in China and to explore the underlying factors. This study aims to offer useful evidence that can refine nursing care strategies and guide policy development within day-care settings.

METHODS: We implemented a comprehensive electronic survey comprising 46 questions targeting older adults across nine day-care centers in Nanjing, China. Employing latent profile analysis (LPA), we systematically examined and categorized the demand characteristics for day-care services. This analysis was conducted using Mplus version 8.3 and SPSS version 26.0 software, ensuring a rigorous and precise methodological approach.

RESULTS: Our study involved a comprehensive survey of 1016 older adults. The participants were categorized into three groups based on their demand for day-care services: high demand (n = 127), medium demand (n = 197), and low demand (n = 692). The low-demand group exhibited higher levels of social support and better activities of daily living (ADL) scores compared to their counterparts. Multivariate regression analysis indicated that older adults characterized by male gender, advanced age, higher levels of education, receipt of support from a child, presence of chronic diseases, and lower social support and ADL scores exhibited a statistically significant inclination towards moderate to high demand for day-care services (p < 0.05).

CONCLUSION: The demand for day-care services for older adults in China is intricately influenced by a complex array of interrelated factors. Tailoring service offerings to meet the varied physical and emotional needs of older adults is essential, with a particular focus on health and wellness management in day-care centers.

PMID:39840478 | DOI:10.1111/phn.13539

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Nevin Manimala Statistics

Incidence Rates and Risks for Reoperations for Nonunion and Adjacent Level Disease: Stopping at L1 versus T10/T11/12

Spine (Phila Pa 1976). 2025 Jan 22. doi: 10.1097/BRS.0000000000005257. Online ahead of print.

ABSTRACT

STUDY DESIGN: A retrospective cohort study.

OBJECTIVE: To determine if there is a difference in reoperations for adjacent segment disease (operative ASD) and nonunion (operative nonunion) in lumbar fusions that stop at T10/T11/T12 versus L1.

SUMMARY OF BACKGROUND DATA: Current lumbar spine surgery is based on the belief that ASD occurs if fusions are stopped at L1 although there is varying evidence to support this assumption.

METHODS: We conducted a cohort study using data from a US-based integrated healthcare system’s Spine Registry of adult patients ≥18 years old with degenerative disc disease/adult lumbar deformity who underwent primary lumbar fusions. The exposure of interest was lumbar fusions stopping at L1 versus T10/T11/T12. Propensity score-weighted Cox proportional hazards regressions were used to evaluate reoperation risk for ASD and for nonunion.

RESULTS: The study cohort included 227 lumbar fusions that stop at L1 and 228 stop at T10/T11/12. Mean age for the cohort was 68.4 years with mean follow-up time of 6.3 years. For caudal level at L5 and S1, we found no statistical differences between operative ASD stopping at L1 versus T10/11/12 (HR=1.03, 95% CI=0.53-2.02, P=0.93 and HR=0.67, 95% CI=0.27-1.67, P=0.39, respectively). For the Short-segment fusions (caudal level: L3,4,5) and Long-segment fusions (L5, S1. S1+ilium) we also found no statistical difference in operative ASD (HR=1.44, 95% CI=0.68-3.09, P=0.34 and HR=0.83, 95% CI=0.52-1.30, P=0.41, respectively). For Long-segment fusions we also found no statistical difference in operative nonunion (HR=0.65, 95% CI=0.20-2.11, P=0.47).

CONCLUSION: Our study provides some evidence against crossing the thoracolumbar junction (TLJ) for individual constructs terminating at S1, as well as for Long-segment fusions, based on comparisons of operative ASD and operative nonunion. However, further research is needed to determine whether this finding holds true for individual constructs with caudal levels at L2, L3, L4, and S1+ilium.

PMID:39840471 | DOI:10.1097/BRS.0000000000005257

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Nevin Manimala Statistics

Association between weight-adjusted waist index and obstructive sleep apnea among adults in the United States: data from NHANES (2005-2008 and 2015-2018)

J Int Med Res. 2025 Jan;53(1):3000605241311450. doi: 10.1177/03000605241311450.

ABSTRACT

OBJECTIVE: We aimed to examine the relationship between the weight-adjusted waist index (WWI) and obstructive sleep apnea (OSA), a condition often caused by obesity, which remains unclear.

METHODS: In this cross-sectional study, we analyzed data from the National Health and Nutrition Examination Survey among adults in the United States (US) aged 20 to 65 years, covering the periods 2005 to 2008 and 2015 to 2018. The study included 8278 participants; we used multivariate logistic regression, restricted cubic splines, and subgroup analyses to explore the relationship between WWI and OSA.

RESULTS: After adjusting for all covariates, each unit increase in WWI was associated with a 30% increase in OSA prevalence (odds ratio = 1.30, 95% confidence interval: 1.20-1.40).

CONCLUSIONS: These findings suggest that WWI, an index reflecting abdominal obesity, can provide important insights into OSA risk assessment. Its strong association with OSA highlights its potential utility in predicting OSA prevalence, particularly among diverse subpopulations. The WWI was associated with a higher prevalence of OSA among US adults and may serve as a valuable tool for risk assessment, early screening, and intervention strategies in clinical practice.

PMID:39840466 | DOI:10.1177/03000605241311450

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Nevin Manimala Statistics

Is videoconference pulmonary rehabilitation associated with improvements in knowledge in people living with COPD? A propensity-matched service-evaluation

Chron Respir Dis. 2025 Jan-Dec;22:14799731241310895. doi: 10.1177/14799731241310895.

ABSTRACT

Introduction: Pulmonary rehabilitation (PR) services are increasingly using alternative programme delivery modes, for example telerehabilitation strategies including videoconferencing, to improve patient choice and accessibility. Although telerehabilitation results in improvements in core outcomes, the effect on knowledge attainment is not known. Aim: To observe the real-world responses of patients choosing to undergo videoconference PR to a matched control group choosing to undergo in-person PR, in terms of knowledge attainment. Methods: Using propensity score matching, 25 people with COPD who completed videoconference PR were matched 1:1 with a control group of 25 people with COPD who completed in-person PR. Knowledge attainment was measured using the Lung Information Needs Questionnaire (LINQ). Results: There was a statistically and clinically significant improvement in LINQ score in both groups (mean (95%CI): videoconference -3.2 (-4.7 to -1.6); in-person -3.0 (-4.5 to -1.4)), with no significant between-group difference (mean (95%CI): 0.2 (-2.0 to -2.4)). 76% and 80% of participants achieved the minimal important difference of the LINQ in the videoconference and in-person PR groups respectively. Conclusion: In conclusion, this real-world service evaluation indicates that videoconference PR may be associated with similar improvements in knowledge attainment as in-person PR, but this requires corroboration due to the small sample size.

PMID:39840462 | DOI:10.1177/14799731241310895

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Nevin Manimala Statistics

Evaluation of Perceptual and Anthropometrical Facial Changes According to Increase in Vertical Dimension of Occlusion

J Oral Rehabil. 2025 Jan 22. doi: 10.1111/joor.13937. Online ahead of print.

ABSTRACT

BACKGROUND: For restorative demands, increased vertical dimension of occlusion (VDO) is sometimes necessary, as facial changes can be perceptible.

OBJECTIVES: This study aimed to evaluate the perception of facial change due to increased VDO and associated soft tissue changes using 3D-scanned facial images.

METHODS: Forty participants with healthy dentition and no loss of VDO were recruited. The VDO was increased by 2, 4, 6 and 8 mm on a semi-adjustable articulator after maxillomandibular impressions. Facebow transfers were taken for each participant to create a personalised device. 3D facial scans were taken with the mandibular occlusal device in place, creating facial capture files from frontal, lateral and anteroposterior views for each scanned data. Sixty evaluators were recruited to consecutively cross-compare maximal intercuspal captures with increased VDO. To evaluate soft tissue changes with increased VDO, facial measurements, total face height, lower face height, lip width, lip height and nasolabial angle were measured thrice in 3D scan images using computer-aided design software. Statistical analysis entailed one-way repeated-measures analysis of variance (α = 0.05).

RESULTS: A 4-mm increase in the VDO showed the highest perceptibility for facial change, varying among evaluator groups. Total face height, lower face height and nasolabial angle increased with VDO, while lip width and height decreased. Each soft tissue measurement differed significantly (p < 0.05).

CONCLUSION: For 3D-scanned facial changes, a 4-mm increase in VDO was the most perceptible difference. Increased VDO affects facial changes.

PMID:39840459 | DOI:10.1111/joor.13937

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Nevin Manimala Statistics

Innovative strategies for minimizing hematoma risk in MRI-guided breast biopsies

Radiol Oncol. 2025 Jan 22. doi: 10.2478/raon-2025-0004. Online ahead of print.

ABSTRACT

BACKGROUND: The study aimed to investigate the reduction of hematoma risk during MRI-guided breast biopsies by evaluating position-dependent intervention parameters and characteristics of the target lesion.

MATERIALS AND METHODS: We retrospectively analyzed 252 percutaneous MRI-guided breast biopsies performed at a single center between January 2013 and December 2023. Two groups were built depending on the severity of relative hematoma formation (using a cut-off ≤ 7.62 cm3 or > 7.62 cm3). Potential influencing variables were assessed, such as patient demographics, interventional parameters related to anatomical landmarks, and lesion characteristics. Fisher’s exact test and Mann-Whitney-U-Test were used to calculate the statistical difference between groups of categorical, dichotomous, and continuous variables. Multivariable logistic regression was used to identify the strongest association with relative hematoma formation.

RESULTS: The univariate analysis showed that relatively larger hematoma occurred significantly more frequently when the patients were younger (P = 0.002), the relative distances from the target lesion to the nipple (P = 0.001) as well as alongside the access path (P = 0.001) were greater and when the vacuum-assisted biopsy system was used in contrast to the Spirotome® (P = 0.035). Multivariable logistic regression analysis also showed that these were independently associated with the occurrence of relatively larger hematomas. Epinephrine in the local anesthetic, lesion location classified by specific quadrant, and pathological findings did not influence the extent of the hematoma.

CONCLUSIONS: Our findings underscore the importance of strategic procedural planning to minimize hematoma occurrence and enhance patient safety during MRI-guided breast biopsy procedures.

PMID:39840427 | DOI:10.2478/raon-2025-0004

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Nevin Manimala Statistics

Surgical Repair of Double Outlet Right Ventricle Infants Guided by Three Dimensional-Computed Tomography Cardiac Modeling and Printing

World J Pediatr Congenit Heart Surg. 2025 Jan 22:21501351241305129. doi: 10.1177/21501351241305129. Online ahead of print.

ABSTRACT

BACKGROUND: Double outlet right ventricle (DORV) is a challenging congenital cardiac lesion to surgically master. We utilize computed tomography-guided-three-dimensional (3D) modeling/printing and novel in-house software to delineate anatomical relationships providing operative insight into the surgical approach. Our intent is to highlight this and showcase our technology.

METHODS: We have created a repository of 3D heart reconstructions allowing for review of DORV patients. 3D intraoperative software anatomical manipulation and physical 3D prints were used to gain insight into DORV anatomy with the assistance of an on-site 3D Lab. The software used (Arc 3D Model Viewer) was designed in-house by our 3D Lab, tested and refined through ongoing use by our cardiothoracic surgery team. It allows for the subtraction and addition of anatomical structures and rotation in all axes. Clinicians can pan into the heart and determine specific anatomical boundaries and relationships.

RESULTS: From 2010 to 2023, our program operated on 71 patients with DORV and our 3D lab has reconstructed 29 3D-hearts. Reconstructions were analyzed using Arc 3D Model Viewer. 3D reconstructions were viewed in our care conferences and intraoperatively allowing for discussion and determination of the optimal operative approach. Overall survival for DORV patients was 96% (68/71) with two mortalities in patients who did not receive 3D reconstructions.

CONCLUSION: 3D reconstruction has allowed decision-making to be moved out of the operating room into the preoperative planning phase. 3D reconstruction is now standard for all DORV patients in our surgical service. We hope to demonstrate this technology with our newly developed Arc 3D Model Viewer and summarize our clinical results.

PMID:39840424 | DOI:10.1177/21501351241305129

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Nevin Manimala Statistics

Exploring Social-Ecological Pathways From Sexual Identity to Sleep Among Chinese Women: Structural Equation Modeling Analysis

JMIR Public Health Surveill. 2025 Jan 21;11:e53549. doi: 10.2196/53549.

ABSTRACT

BACKGROUND: Women and sexual minority individuals have been found to be at higher risk for experiencing poor sleep health compared to their counterparts. However, research on the sleep health of sexual minority women (SMW) is lacking in China.

OBJECTIVE: This study aimed to examine sleep quality and social support for Chinese women with varied sexual identities, and then investigate the in-depth relationships between sexual identity and sleep.

METHODS: This was a cross-sectional web-based survey. All participants completed a structured questionnaire containing a set of sociodemographic items referring to the social-ecological model of sleep health, the Pittsburgh Sleep Quality Index, the Social Support Rating Scale, and social relationships and environment domains of the World Health Organization Quality of Life-abbreviated short version. Pearson correlation coefficients were used to examine the relationship between sleep quality and social support as well as the two domains of quality of life. Structural equation modeling analysis was used to explore the social-ecological relationships.

RESULTS: A total of 250 cisgender heterosexual women (CHW) and 259 SMW were recruited from July to September 2021. A total of 241 (47.3%) women experienced poor sleep quality and the rate was significantly higher in SMW than in CHW (55.2% vs 39.2%, P<.001). Around one-fifth of SMW reported low levels of social support, which was significantly higher than that of CHW (21.6% vs 5.6%, P<.001). Pearson correlations showed that overall sleep quality was significantly negatively associated with social support with weak correlations (r=-0.26, P<.001). The final structural equation modeling analysis with satisfactory fit indices identified 6 social-ecological pathways, showing that alcohol use, objective support, utilization of support, and perceived social relationship and environment quality of life played important roles in the sleep quality of individuals from their sexual identity.

CONCLUSIONS: SMW experienced poorer sleep quality compared to CHW. Further research is recommended to address the modifiable factors affecting sleep and then implement tailored sleep improvement programs.

PMID:39840408 | DOI:10.2196/53549

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Nevin Manimala Statistics

Efficiency of Polyethylene Terephthalate Glycol Thermoplastic Material to Functional and Expansion Forces in Orthodontic Applications: An Experimental Study

ScientificWorldJournal. 2025 Jan 10;2025:7232779. doi: 10.1155/tswj/7232779. eCollection 2025.

ABSTRACT

Background: While polyethylene terephthalate glycol (PETG) is widely used in orthodontic appliances such as clear aligners and retainers, there is limited experimental data assessing its performance under functional stresses, such as those encountered during dental movements and palatal expansion. Objective: This study aims to evaluate the ability of PETG thermoplastic material to withstand deformation under functional and expansion forces, specifically within the context of orthodontic applications. Subjects and Methods: To estimate the firmness of the screw within the appliance, a universal Instron testing machine was used to record the forces released by each activation of the expander within the upper part of 10 clear modified twin blocks (MTBs) made from PETG and compare it with that released by 10 conventional twin blocks (CTBs). On the other hand, to determine the ability of the thermoplastic appliance to withstand the deformation during functional forces, a three-point bending test was used to investigate the response of both appliances under static loading. Independent samples t-test was used to compare the differences between groups. Results: Both CTB and MTB groups follow the same pattern of increase and decrease in the amount of mean load with the CTB group line showing a considerably higher amount of mean load reaching the peak (334.5 N) at turn 25 of screw activation while the peak of mean load for MTB group was equal to 252.6 N at turn 23. There was a statistically significant difference between the CTB and MTB groups in the three-point bending test (p=0.001). However, both appliances did not deform at the required force. Conclusions: The MTB can withstand both required expansion and functional load without deformation. Trial Registration: ClinicalTrials.gov identifier: NCT06116500.

PMID:39840371 | PMC:PMC11748742 | DOI:10.1155/tswj/7232779

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Nevin Manimala Statistics

Diverse pore ordering in porous silica: synthesis and quantitative structural insights based on combining scattering and imaging techniques

Phys Chem Chem Phys. 2025 Jan 21. doi: 10.1039/d4cp04056b. Online ahead of print.

ABSTRACT

Mesoporous silica exhibits a diverse range of applications owing to its pore structure and inter-pore correlation. Consequently, quantitative characterization of its mesoscopic structure is extremely crucial to reciprocate its potential applications. In this work, we utilized the chemical and aerosol routes to successfully synthesize granular, porous silica with an average pore size in the range of ∼5-10 nm and different degrees of structural correlation among its pores. To delve into their structural morphology, we employed complementary characterization techniques, including X-ray scattering, electron microscopy, and gas adsorption. Small-angle X-ray scattering (SAXS) was used to obtain statistically averaged quantitative information about their porous network. Field-emission scanning electron microscopy (FESEM) and high-resolution transmission electron microscopy (HRTEM) were used to identify their morphology and positional ordering. The information from these three different techniques was indeed complementary in nature. Thus, combining the comparative results from the detailed analyses using scattering, imaging and gas adsorption techniques is effective in providing an overall quantitative understanding about the morphology and pore correlations in this type of porous material with diverse pore structures.

PMID:39836466 | DOI:10.1039/d4cp04056b