Categories
Nevin Manimala Statistics

Acceptability and completeness of vaccination schedules recommended for transgender women and travestis in the city of São Paulo, Brazil: a cross-sectional study, 2019-2020

Epidemiol Serv Saude. 2025 Jan 13;33(spe1):e2024341. doi: 10.1590/S2237-96222024v33e2024341.especial.en. eCollection 2025.

ABSTRACT

OBJECTIVE: To assess adherence to and completeness of vaccination schedules against human papillomavirus (HPV) and hepatitis A and B among transgender women and travestis in São Paulo, capital city of São Paulo state.

METHODS: This was a secondary data analysis of the multicenter TransOdara study. Data were collected from 403 transgender women and travestis aged 18 years or older, recruited through respondent-driven sampling between December 2019 and October 2020.

RESULTS: High adherence to vaccines was observed (88.8%), but completeness of the analyzed vaccination schedules was low: 12% (95%CI 8.0; 17.3) for hepatitis A, 7.2% (95%CI 3.5; 12.8) for hepatitis B and 8.1% (95%CI 3.0; 16.6) for HPV, with no statistically significant differences between them.

CONCLUSION: Despite high adherence, the low completion of vaccination schedules highlighted the need for diversified strategies to improve vaccination coverage and reduce the prevalence of vaccine-preventable sexually transmitted infections in this population.

PMID:39813582 | DOI:10.1590/S2237-96222024v33e2024341.especial.en

Categories
Nevin Manimala Statistics

Active transportation is associated with lower obesity risk: generalized structural equations model applied to physical activity

Cad Saude Publica. 2025 Jan 13;40(12):e00035624. doi: 10.1590/0102-311XEN035624. eCollection 2025.

ABSTRACT

This study aimed to identify latent (unobservable) dimensions representing specific physical activity-related behaviors and explore their potential effects on obesity burden and spatial distribution in Colombia. A cross-sectional study (n = 9,658) was conducted based on the Colombian National Survey of Nutritional Status. A generalized structural equations model was proposed, combining exposure and measurement models to define a disease model. Modeling identified latent dimensions of physical activity focused on screen time and means of transportation and estimated their direct and indirect effects on obesity occurrence. Mapping techniques were used to illustrate adherence to these dimensions. The latent dimensions identified were named “Screens use” and “Active transportation”; the latter was inversely associated with obesity occurrence (p = 0.004), with the use of bicycles being the dominant variable, contrasting with the use of motor vehicles. The mapping showed that departments with the highest adherence to the “Active transportation” construct have a lower prevalence of obesity. Bicycle use, as opposed to non-active transportation, represented a dimension of physical activity-related behaviors with a protective effect against obesity. This suggests that active transportation may be a crucial factor in the designing preventive interventions. Moreover, social inequalities may be contributing to the obesity epidemic and physical activity behaviors in Colombia, requiring equitable and multisectoral responses.

PMID:39813567 | DOI:10.1590/0102-311XEN035624

Categories
Nevin Manimala Statistics

Overall excess mortality and COVID-19 mortality in Brazil and Brazilian regions in 2020

Cad Saude Publica. 2025 Jan 13;40(11):e00217323. doi: 10.1590/0102-311XPT217323. eCollection 2025.

ABSTRACT

This study aimed to evaluate the overall excess mortality and COVID-19 mortality in the regions of Brazil, in 2020, by sex and age group. An ecological study was carried out to calculate the overall excess mortality, by sex and age group, using the expected number of deaths in a non-pandemic context and the deaths observed in 2020. Data on deaths were extracted from the Brazilian Mortality Information System, in addition to population data from the Brazilian Institute of Geography and Statistics. Excess mortality was calculated considering: the difference between the mortality rates observed in 2020 and the average of the rates from 2015 to 2019, standardized by age; and the difference between observed deaths obtained via a quasi-Poisson model and the deaths expected for 2020. In Brazil, the standardized overall mortality rate in 2020 was 590 deaths per 100,000 inhabitants, with excess mortality of 44 deaths per 100,000 inhabitants, while the mortality rate from COVID-19 was 79 deaths per 100,000 inhabitants. The highest overall mortality rates were observed in the North and Northeast regions. The excess deaths estimated by the ratio between observed and expected deaths nationwide in 2020 was 16%; of which 17% were males, 16% were females, 7% were individuals from 0 to 59 years old, and 20% were individuals aged 60 years or older. These outcomes enabled a better understanding on the impact of the COVID-19 pandemic on the mortality in Brazil in 2020, indicating a more pronounced excess mortality in the North, Northeast and Central-West regions and among men older than 60 years.

PMID:39813565 | DOI:10.1590/0102-311XPT217323

Categories
Nevin Manimala Statistics

Therapeutic itineraries shared by users of specialized mental health services: a cluster analysis

Cad Saude Publica. 2025 Jan 13;40(11):e00052624. doi: 10.1590/0102-311XPT052624. eCollection 2025.

ABSTRACT

This study aimed to identify the existence of therapeutic itineraries shared by users of specialized mental health services in a medium-sized municipality. This is a cross-sectional study, carried out from August to November 2019 including 341 users of specialized mental health services in the municipality of Itatiba, São Paulo State, Brazil. To identify the itineraries, based on a set of variables, the users were grouped with clustering. The best measure of silhouette of cohesion and separation (> 0.3) for the clusters was achieved based on four variables: situation in which the mental health problem was identified, place of first care, origin of referral to the current service, and bond maintenance with primary health care (PHC). The clusters identified in the study demonstrated: (1) low participation of PHC in welcoming new cases, with most of the care taking place in specialized services; (2) high proportion of cases identified in crisis situations; (3) low participation of PHC in the referral of cases, with high access to specialized services by spontaneous demand; (4) lack of continuity in PHC services after entering the specialized service. The study highlighted significant weaknesses in the studied healthcare network, evincing the need to develop strategies that foster the services integration, especially regarding PHC, both to favor access to specialized care in a timely manner and to enable the continuity of care between different healthcare facilities.

PMID:39813561 | DOI:10.1590/0102-311XPT052624

Categories
Nevin Manimala Statistics

Vaccination opportunity in children up to 6 months old born in 2017 and 2018 in the city of Londrina-PR, Brazil: a population-based survey

Epidemiol Serv Saude. 2025 Jan 10;33(spe2):e2024432. doi: 10.1590/S2237-96222024v33e2024432.especial2.en. eCollection 2025.

ABSTRACT

OBJECTIVE: To evaluate opportunity for vaccination in children born alive in Londrina, up to 6 months old and the relationship between socioeconomic stratum and vaccination regularity.

METHOD: Population survey study based on a retrospective cohort of children born in 2017 and 2018 that identified vaccines not administered in a given session. Vaccination regularity was compared between socioeconomic strata using Pearson’s chi-square test.

RESULTS: Out of 456 vaccination cards, the proportion of vaccination opportunities not recovered for doses to be administered at birth and at two, four and six months was 5.0% (95%CI 3.1;7.5), 4. 5% (95%CI 2.8;6.9), 7.2% (95%CI 5.0;10.2) and 2.1% (95%CI 1.0;4.0), respectively. There was no statistical difference in vaccination regularity between the strata.

CONCLUSION: Missed opportunities for vaccination were found at all ages. Socioeconomic stratum did not influence vaccination regularity.

PMID:39813547 | DOI:10.1590/S2237-96222024v33e2024432.especial2.en

Categories
Nevin Manimala Statistics

Vaccination coverage in children up to 2 years old born in 2017 and 2018 in the municipalities of São Paulo and Campinas, Brazil: comparison of the results of a national survey and the National Immunization Program Information System

Epidemiol Serv Saude. 2025 Jan 10;33(spe2):e2023539. doi: 10.1590/S2237-96222024v33e2023539.especial2.en. eCollection 2025.

ABSTRACT

OBJECTIVE: To estimate and compare vaccination coverage among children born in 2017-2018 in São Paulo and Campinas, according to the Vaccination Coverage Survey (ICV 2020) and the National Immunization Program Information System (SI-PNI).

METHODS: ICV 2020 analyzed vaccination card records. Coverage was calculated and compared to doses recorded on the SI-PNI, divided by the target population.

RESULTS: In São Paulo, according to ICV, in 2017 only BCG (91.7%; 95%CI 87.0;94.7) and rotavirus first dose (90.6%; 95%CI 86.5;93.5) achieved the goals; in 2018, BCG (93.4%; 95%CI 89.5;95.8), rotavirus first dose (90.5%; 95%CI 85.3;94.0), pneumococcal first dose (95.3%; 95%CI 91.7;97.4), meningococcal C first dose (95.1%; 95%CI 91.5;97.2) and pneumococcal second dose (95.0%; 95%CI 91.4;95.0). In Campinas, only BCG achieved the target in 2017 (93.0%; 95%CI 88.8;95.7) and none in 2018. According to the SI-PNI, no vaccine achieved the target in either city.

CONCLUSION: Vaccination coverage was lower than expected and more precise estimates are necessary for adequate monitoring of childhood vaccination status.

PMID:39813546 | DOI:10.1590/S2237-96222024v33e2023539.especial2.en

Categories
Nevin Manimala Statistics

Factors associated with vaccination coverage in children up to 15 months old, born in 2017-2018 in the city of Natal/RN, Brazil: a population-based survey

Epidemiol Serv Saude. 2025 Jan 10;33(spe2):e20231307. doi: 10.1590/S2237-96222024v33e20231307.especial2.en. eCollection 2025.

ABSTRACT

OBJECTIVE: To estimate vaccination coverage and analyze factors associated with full vaccination among children up to 15 months old in the city of Natal-RN, Brazil.

METHODS: Population-based survey with data recorded on children’s vaccination cards and interviews conducted in 2020 and 2021. Analysis of factors associated with complete vaccination was performed by calculating prevalence ratios (PR) and 95% confidence intervals (95%CI) using Poisson regression.

RESULTS: Among 688 children studied, vaccination coverage was 45.4% (95%CI 37.2;53.9) and 15.5% (95%CI 10.6;22.2) for valid and on-time doses, respectively. Higher vaccination coverage was associated with females (PR=1.08; 95%CI 0.78;1.48) and socioeconomic strata C and D (PR=1.44; 95%CI 1.03;2.02).

CONCLUSIONS: The results demonstrate that the city of Natal has low vaccination coverage for all immunobiologicals.

PMID:39813545 | DOI:10.1590/S2237-96222024v33e20231307.especial2.en

Categories
Nevin Manimala Statistics

Analysis of polio vaccination status in a cohort of live births in 2017 and 2018 in Brazilian cities: a national vaccination coverage survey

Epidemiol Serv Saude. 2025 Jan 10;33(spe2):e20231303. doi: 10.1590/S2237-96222024v33e20231303.en. eCollection 2025.

ABSTRACT

OBJECTIVE: To describe the polio vaccination status in 26 state capitals, the Federal District, and 12 municipalities in Brazil, among children born between 2017 and 2018.

METHODS: This was a population-based household survey conducted from 2020 to 2022, which assessed polio vaccination coverage in children, considering valid, administered, and timely doses by municipality.

RESULTS: Data were collected from 37,801 children. Vaccination coverage for the complete valid dose schedule was 87.5% (95%CI 86.2;88.7), dropping to 79.6% (95%CI 78.1;81.0), when the booster dose was considered. The dropout rate was 4.5% for the complete schedule, and 11.7% for the first booster. There was no correlation between campaign implementation and high coverage.

CONCLUSION: Vaccination coverage for the complete valid dose schedule and the first booster did not meet the 95.0% target. Regional disparities and the association between vaccination coverage and social indicators should be taken into consideration in strategies to increase coverage.

PMID:39813544 | DOI:10.1590/S2237-96222024v33e20231303.en

Categories
Nevin Manimala Statistics

Vaccination coverage, vaccine hesitancy and factors associated with incomplete vaccination: a household survey conducted with children born between 2017 and 2018 in the inland municipalities of Northeastern Brazil

Epidemiol Serv Saude. 2025 Jan 10;33(spe2):e20231224. doi: 10.1590/S2237-96222024v33e20231224.especial2.en. eCollection 2025.

ABSTRACT

OBJECTIVE: To analyze vaccination coverage and factors associated with incomplete vaccination in inland municipalities of Northeastern Brazil.

METHODS: This was a household survey using cluster sampling conducted in Vitória da Conquista, Bahia state, Caruaru, Pernambuco state, Sobral, Ceará state and Imperatriz, Maranhão state between 2020 and 2022. Vaccination coverage by valid doses and vaccine hesitancy were analyzed, with the odds ratio (OR) estimated and adjusted using logistic regression.

RESULTS: Among 1,847 children, complete vaccination coverage was 49.2% (95%CI 43.9;54.5). Factors associated with incomplete vaccination included: higher income (OR 1.53; 95%CI 1.02;2.31), residence in Sobral (OR 4.35; 95%CI 3.04; 6.21) and >1 child (OR 1.20; 95%CI 1.11;1.32). Parental decision not to vaccinate and difficulties in traveling to vaccination centers contributed to vaccine hesitancy.

CONCLUSION: Low vaccination coverage and incomplete vaccination were associated with social issues in the socioeconomic strata analyzed.

PMID:39813543 | DOI:10.1590/S2237-96222024v33e20231224.especial2.en

Categories
Nevin Manimala Statistics

Vaccination coverage and factors associated with incomplete polio vaccine schedule in children born in 2017-2018, in state capitals and interior region municipalities of Northeast Brazil

Epidemiol Serv Saude. 2025 Jan 10;33(spe2):e20231219. doi: 10.1590/S2237-96222024v33e20231219.especial2.en. eCollection 2025.

ABSTRACT

OBJECTIVE: To analyse vaccination coverage and factors associated with incomplete polio vaccination in a cohort of children born in 2017-2018, in state capitals and interior region municipalities of Northeast Brazil.

METHODS: Household survey of children aged ≤24 months conducted between 2020 and 2022. Vaccination coverage and dropout rates were estimated, as well as factors associated with incomplete vaccination, analyzed by calculating odds ratios (OR) and 95% confidence intervals (95%CI).

RESULTS: : Among 12,137 children, vaccination coverage (4 doses) was 80.9% (95%CI 78.4;83.1); 8.4% were not vaccinated. Not having a vaccination card (OR=18.06; 95%CI 10.01;32.61) and use of private services (OR=1.46; 95%CI 1.23;1.74) were associated with incomplete vaccination. Higher dropout rates were found for the booster dose, especially in the highest stratum.

CONCLUSION: Low vaccination coverage, poor dose follow-up and high dropout rates were found for polio vaccines in the areas studied.

PMID:39813542 | DOI:10.1590/S2237-96222024v33e20231219.especial2.en