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Nevin Manimala Statistics

Cone-beam computed tomographic analysis of maxillary sinus septa among Yemeni population: a cross-sectional study

BMC Oral Health. 2023 Jul 8;23(1):466. doi: 10.1186/s12903-023-03124-6.

ABSTRACT

BACKGROUND: Maxillary sinus septa increase perforation risk of Schneiderian membrane during the sinus floor elevation (SFE). Cone Beam Computed Tomography (CBCT) allows for a more precise assessment of the septal position; thus, preoperative CBCT analysis is substantial to avoid possible complications. This study aims to investigate the 3D characteristics of the maxillary sinus septa based on CBCT images. To our knowledge, no study reported the CBCT-based investigation for the sinus septa among Yemeni population.

MATERIALS AND METHODS: This is a retrospective cross-sectional analysis of 880 sinus CBCT images 440 patients. The septa prevalence, locations, orientations, morphology, and associated factors were analyzed. The effect of age, gender, and dental status on the sinus septa and the relationship between sinus membrane pathology and sinus septa were also analyzed. Anatomage (Invivo version 6) was used for CBCT images analysis. Descriptive and analytical statistics were performed, and a P-value < 0.05 was significantly considered.

RESULTS: The maxillary sinus septa were found among 63.9% of patients and 47% of sinuses. The average septa height was 5.2 mm. 15.7% of patients had septa in the right maxilla, 18% in the left, and 30.2% in both. Gender, age, and dental condition had no influence on the presence of septa, and septa presence did not influence sinus membrane pathology. Many septa originated from the floor (54.5%), located in the middle (43%), with coronal orientation (66%) and complete configuration (58.2%).

CONCLUSION: Based on our findings, the septa prevalence, locations, orientations, and morphology were significant and equivalent to the highest recorded in the literature yet. Thus, when sinus floor elevation is planned, CBCT imaging of the maxillary sinus is recommended for safe dental implantation.

PMID:37422645 | DOI:10.1186/s12903-023-03124-6

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Nevin Manimala Statistics

Knowledge, attitudes and practice of infection prevention and control in the CT suite

BMC Health Serv Res. 2023 Jul 8;23(1):741. doi: 10.1186/s12913-023-09779-9.

ABSTRACT

BACKGROUND: Infection, prevention, and control (IPC) practices are essential to protect patients and staff within healthcare facilities. Radiology departments cater to both inpatients and outpatients, and breaches of IPC practice have led to outbreaks of disease within healthcare facilities. This study aims to examine the knowledge, attitudes and practice (KAP) of computed tomography (CT) radiographers and nurses in their infection, prevention, and control (IPC) practice. The KAP components focuses on the CT environment, contrast injector use, and workplace factors that impact IPC practice.

METHODS: A cross-sectional KAP survey was distributed online to Australian CT radiographers and radiology nurses across different institutions. The survey covered demographics, each KAP component, and workplace culture. Spearman’s correlation was used to compare KAP scores. Kruskal-Wallis test was used to compare the KAP scores between demographic categories, and Chi Square was used to compare demographic data with workplace culture.

RESULTS: There were 147 respondents, 127 of which were radiographers and 20 were nurses. There was a moderate positive correlation between knowledge and attitude for radiographers (rho = 0.394, p < 0.001). Radiographers also had a moderate positive relationship between attitudes and practice (rho = 0.466, p < 0.001). Both radiographers and nurses scored high in the knowledge section of the survey, but nurses had statistically significant higher practice scores than radiographers (p = 0.014). CT radiographers who had an IPC team in their workplace or worked in public hospitals, had statistically significant higher attitudes and practice scores. Age, education, and years of experience did not impact on KAP scores.

CONCLUSION: The study found that radiographers and nurses had a good baseline knowledge of standard precautions. IPC teams and continued training is important to positively influence knowledge and attitudes of health professionals towards IPC practice. The KAP survey was a useful tool to assess the knowledge, attitudes, and practice on IPC of CT radiographers and nurses and identified areas for education, interventions, and leadership.

PMID:37422620 | DOI:10.1186/s12913-023-09779-9

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Nevin Manimala Statistics

Long-term outcomes in patients with Burkitt lymphoma older than 65 years: an analysis of the Texas Cancer Registry

Ann Hematol. 2023 Jul 8. doi: 10.1007/s00277-023-05328-w. Online ahead of print.

ABSTRACT

Burkitt lymphoma (BL) is an extremely aggressive but curable subtype of non-Hodgkin lymphoma. While younger patients have excellent outcomes in response to aggressive chemoimmunotherapy, the rarity of this disease in older patients and limitations caused by age, comorbidities, and performance status may negate survival advantages. This analysis assessed outcomes of older adults with BL through data provided by the Texas Cancer Registry (TCR). Patients ≥65 years with BL were assessed. Patients were dichotomized into 1997-2007 and 2008-2018. Median overall survival (OS) and disease-specific survival (DSS) were assessed using Kaplan-Meier methodology, and covariates including age, race, sex, stage, primary site, and poverty index were analyzed using Pearson Chi-squared analysis. Odds ratio (OR) with 95% confidence intervals (CI) was used to assess factors contributing to patients not offered systemic therapy. P value <0.05 was considered statistically significant. Non-BL mortality events were also categorized. There were 325 adults, 167 in 1997-2007 and 158 in 2008-2018; 106 (63.5%) and 121 (76.6%) received systemic therapy, a trend that increased with time (p = 0.010). Median OS for 1997-2007 and 2008-2018 was 5 months (95% CI 2.469, 7.531) and 9 months (95% CI 0.000, 19.154) (p = 0.013), and DSS was 72 months (95% CI 56.397, 87.603) (p = 0.604) and not reached, respectively. For patients that received systemic therapy, median OS was 8 months (95% CI 1.278, 14.722) and 26 months (95% CI 5.824, 46.176) (p = 0.072), respectively, and DSS was 79 months (95% CI: 56.416, 101.584) and not reached, respectively (p = 0.607). Age ≥75 years (HR 1.39 [95% CI 1.078, 1.791], p = 0.011) and non-Hispanic whites (HR 1.407 [95% CI 1.024, 1.935], p = 0.035) had poorer outcomes, and patients at the 20-100% poverty index (OR 0.387 [95% CI 0.163, 0.921], p = 0.032) and increasing age at diagnosis (OR 0.947 [95% CI 0.913, 0.983], p = 0.004) were less likely to receive systemic therapy. Of 259 (79.7%) deaths, 62 (23.9%) were non-BL deaths, and 6 (9.6%) of these were from a second cancer. This two-decade analysis of older Texas patients with BL indicates a significant improvement in OS over time. Although patients were more likely to receive systemic therapy over time, treatment disparities existed in patients residing in poverty-stricken regions of Texas and in advancing age. These statewide findings reflect an unmet national need to find a systemic therapeutic strategy that can be tolerated by and augment outcomes in the growing elderly population.

PMID:37422592 | DOI:10.1007/s00277-023-05328-w

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Nevin Manimala Statistics

Apnea-hypopnea index and the polysomnographic risk factors for predicting 5- to 8-year mortality in patients with OSA

Sleep Breath. 2023 Jul 8. doi: 10.1007/s11325-023-02868-3. Online ahead of print.

ABSTRACT

BACKGROUND: The purpose of this study was to investigate the long-term mortality rates of patients with obstructive sleep apnea (OSA) who received an overnight polysomnogram (PSG) for obtaining the diagnosis and to determine the relationship between PSG parameters and overall mortality.

METHODS: Between 2007 and 2013, patients who had overnight PSG and were diagnosed with OSA were included in the study. Factors which are thought to influence mortality were assessed for 5-year and overall survival using the log rank test and Kaplan-Meier survival curves. Using multivariable Cox regression analysis, a model was constructed for factors influencing 5-year and overall survival.

RESULTS: A total of 762 patients with a mean age of 52.7 (±10.8) and a dominance of men (74.7%) were studied. Gender, OSA severity subgroups, and apnea hypopnea index (AHI) were not statistically significantly associated with either 5-year or overall mortality (p<0.05 for both). Age, having a cardiovascular comorbidity, proportion of rapid eye movement (%REM), and total sleep time with an oxyhemoglobin saturation of less than 90% (T90) all showed a significant correlation with overall all-cause mortality in the model. For 5-year mortality and overall mortality, the hazard ration (HR) for T90 was 3.6 (95% CI (1.6-8.0) p=0.001) and 3 (95% CI (1.6-5.7) p=0.001), respectively.

CONCLUSION: The study findings suggest that not AHI but PSG parameters of hypoxia, mainly T90, having cardiovascular comorbidity, and %REM sleep were significant risk factors for all-cause mortality in patients with OSA. The association of OSA, hypoxia, and mortality is an area that deserves further study.

PMID:37422579 | DOI:10.1007/s11325-023-02868-3

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Nevin Manimala Statistics

Aseptic revisions and pulmonary embolism after surgical treatment of femoral neck fractures with cemented and cementless hemiarthroplasty in Germany : An analysis from the Germany Arthroplasty Registry (EPRD)

Orthopadie (Heidelb). 2023 Jul 8. doi: 10.1007/s00132-023-04412-3. Online ahead of print.

ABSTRACT

BACKGROUND: Femoral neck fractures (FNF) are among the most common fractures in Germany and are often treated by hemiarthroplasty (HA). The aim of this study was to compare the occurrence of aseptic revisions after cemented and uncemented HA for the treatment of FNF. Secondly, the rate of pulmonary embolism was investigated.

METHODS: Data collection for this study was performed using the German Arthroplasty Registry (EPRD). HAs after FNF were divided into subgroups stratified by stem fixation (cemented vs uncemented) and paired according to age, sex, BMI, and the Elixhauser score using Mahalanobis distance matching.

RESULTS: Examination of 18,180 matched cases showed a significantly increased rate of aseptic revisions in uncemented HA (p < 0.0001). After 1 month 2.5% of HAs with uncemented stems required an aseptic revision, whereas 1.5% were reported in cemented HA. After 1 and 3 years’ follow-up 3.9% and 4.5% of uncemented HA and 2.2% and 2.5% of cemented HA needed aseptic revision surgery. In particular, the proportion of periprosthetic fractures was increased in cementless implanted HA (p < 0.0001). During in-patient stays, pulmonary emboli occurred more frequently after cemented HA (0.81% vs 0.53% in cementless HA [OR: 1.53; p = 0.057]).

CONCLUSION: For uncemented hemiarthroplasties a statistically significantly increased rate of aseptic revisions and periprosthetic fractures was evident within a time period of 5 years after implantation. During the in-hospital stay, patients with cemented HA experienced an increased rate of pulmonary embolism compared with patients with cementless HA, but this difference was not statistically significant. Based on the present results, with knowledge of prevention measures and the correct cementation technique, the use of cemented HA should be preferred in the treatment of femoral neck fractures.

PMID:37422578 | DOI:10.1007/s00132-023-04412-3

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Nevin Manimala Statistics

Exploring the nonlinear relationship among financial development, human capital and CO2 emissions: a comparative study of South and East Asian emerging economies

Environ Sci Pollut Res Int. 2023 Jul 8. doi: 10.1007/s11356-023-28512-x. Online ahead of print.

ABSTRACT

Despite worldwide commitments to reduce fossil fuel consumption in favour of alternative energies, several countries still rely on carbon-intensive sources to meet their energy demands. The previous studies show inconsistent results on the association between financial development and CO2 emissions. As a result, the impact of financial development, human capital, economic growth and energy efficiency on CO2 emission is evaluated here. Empirical research on a panel of 13 South and East Asian (SEA) nations between 1995 and 2021 using the CS-ARDL. Estimates from the empirical analysis considering energy efficiency, human capital, economic growth and overall energy use yield different findings. Financial development has a negative effect on CO2 emission, while economic growth positively impacts CO2 emission. The data also show that improving human capital and energy efficiency has a positive, though statistically insignificant, impact on CO2 emission. According to the causes and effects analysis, CO2 emission will be influenced by policies that aim to improve financial development, human capital, and energy efficiency, but not vice versa. Policy considerations that can be implemented in light of these findings and sustainable development goals can be accomplished by promoting financial resources and human capital.

PMID:37422559 | DOI:10.1007/s11356-023-28512-x

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Nevin Manimala Statistics

Diagnostic trajectories of mental disorders in children and adolescents: a cohort study

Eur Child Adolesc Psychiatry. 2023 Jul 8. doi: 10.1007/s00787-023-02254-0. Online ahead of print.

ABSTRACT

Mental disorders in children and adolescents may follow different trajectories, such as remission, change of diagnosis, or addition of two or more comorbid diagnoses, showing a heterotypic pattern. This study aims to describe the main diagnostic trajectories across a broad range of mental disorder diagnostic categories, from childhood to adolescence and from adolescence to young adulthood in a clinical population. A prospective study was conducted among a clinical sample of children and adolescents who were aged 3-17 years at the face-to-face baseline interview. Electronic health records of these participants were reviewed 10 years later. The diagnostic stability over time was examined using the kappa coefficient, and factors associated with stability were explored using simple logistic regression. The study included a sample of 691 participants. The kappa coefficient for diagnostic stability across all diagnoses was 0.574 for the transition from childhood to adulthood, 0.614 from childhood to adolescence, and 0.733 from adolescence to adulthood. Neurodevelopmental diagnoses had the highest stability. Factors associated with higher diagnostic stability included family history of mental disorders, receiving psychopharmacological treatment, and symptom severity at baseline. We found a variable diagnostic stability across different diagnoses and age categories. The different life transitions represent complex periods that should not be overlooked from a clinical standpoint. An appropriate transition from child and adolescent mental health services to adult mental health services may have a positive impact on children and adolescents with mental disorders.

PMID:37422547 | DOI:10.1007/s00787-023-02254-0

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Nevin Manimala Statistics

Human-caused wolf mortality persists for years after discontinuation of hunting

Sci Rep. 2023 Jul 8;13(1):11084. doi: 10.1038/s41598-023-38148-z.

ABSTRACT

By the mid-twentieth century, wolves were nearly extinct in the lower 48 states, with a small number surviving in northern Minnesota. After wolves were placed on the endangered species list in 1973, the northern Minnesota wolf population increased and stabilized by the early 2000s. A wolf trophy hunt was introduced in 2012-2014 and then halted by a court order in December 2014. The Minnesota Department of Natural Resources collected wolf radiotelemetry data for the years 2004-2019. Statistical analysis showed that wolf mortality remained close to constant from 2004 until the initiation of the hunt, and that mortality doubled with the initiation of the first hunting and trapping season in 2012, remaining at a nearly constant elevated level through 2019. Notably, average annual wolf mortality increased from 21.7% before wolf hunting seasons (10.0% by human causes and 11.7% natural causes) to 43.4% (35.8% by human causes and 7.6% natural causes). The fine-grained statistical trend implies that human-caused mortality increased sharply during the hunting seasons, while natural mortality initially dropped. After the hunt’s discontinuation, human-caused mortality remained higher than prior to the hunting seasons throughout the five years of the available after-hunt radiotelemetry data.

PMID:37422540 | DOI:10.1038/s41598-023-38148-z

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Nevin Manimala Statistics

Extension and update of multiscale monthly household carbon footprint in Japan from 2011 to 2022

Sci Data. 2023 Jul 8;10(1):439. doi: 10.1038/s41597-023-02329-2.

ABSTRACT

Household consumption significantly contributes to greenhouse gas emissions as it is the largest component of final demand in the national accounting system. Nevertheless, there is an apparent lack of comprehensive and consistent datasets detailing emissions from household consumption. Here, we expand and update Japan’s multiscale monthly household carbon footprint from January 2011 to September 2022, combining data from government statistics and surveys. We constructed a dataset comprising 37,692 direct and 4,852,845 indirect emission records, covering households at the national, regional, and prefectural city levels. The dataset provides critical spatiotemporal information that allows for revealing carbon emission patterns, pinpointing primary sources of emissions, and discerning regional variances. Moreover, the inclusion of micro-scale carbon footprint data enables the identification of specific consumption habits, thereby regulating individual consumption behavior to achieve a low-carbon society.

PMID:37422522 | DOI:10.1038/s41597-023-02329-2

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Nevin Manimala Statistics

Prediction of injuries, traumas and musculoskeletal pain in elite Olympic and Paralympic volleyball players

Sci Rep. 2023 Jul 8;13(1):11064. doi: 10.1038/s41598-023-38112-x.

ABSTRACT

The study aimed to identify the prevalence and location of injuries, traumas, and musculoskeletal complaints in Paralympic and Olympic volleyball players with different impairments and initial playing positions (sitting/standing); and to identify the predictors of the abovementioned variables using a multivariate CRT model. Seventy-five elite volleyball players from seven countries took part in the study. They were divided into three study groups: (SG1)-lateral amputee Paralympic volleyball players, (SG2)-able-bodied Paralympic volleyball players, (SG3)-able-bodied Olympic volleyball players. The prevalence and location of the analyzed variables were assessed with surveys quessionaires, while game-related statistics was interpreted based on the CRT analysis. Regardless of the impairment or initial playing position, both the humeral and knee joints were found to be the most frequent locations of musculoskeletal pain and/or injuries in all studied groups, followed by LBP. Players from SG1 and SG3 were characterized by an almost identical prevalence of reported musculoskeletal pain and injuries, what was not noted in SG2. Extrinsic compensatory mechanism (playing position) may be a crucial variable for prediction of musculoskeletal pain and injuries in volleyball players. Lower limb amputation seems to impact the prevalence of musculoskeletal complaints. Training volume may predict the prevalence of LBP.

PMID:37422521 | DOI:10.1038/s41598-023-38112-x