Tag: statistics

Bull Math Biol. 2023 Feb 3;85(3):20. doi: 10.1007/s11538-023-01123-w.

ABSTRACT

Syphilis and HIV infections form a dangerous combination. In this paper, we propose an epidemic model of HIV-syphilis coinfection. The model always has a unique disease-free equilibrium, which is stable when both reproduction numbers of syphilis and HIV are less than 1. If the reproduction number of syphilis (HIV) is greater than 1, there exists a unique boundary equilibrium of syphilis (HIV), which is locally stable if the invasion number of HIV (syphilis) is less than 1. Coexistence equilibrium exists and is stable when all reproduction numbers and invasion numbers are greater than 1. Using data of syphilis cases and HIV cases from the US, we estimated that both reproduction numbers for syphilis and HIV are slightly greater than 1, and the boundary equilibrium of syphilis is stable. In addition, we observed competition between the two diseases. Treatment for primary syphilis is more important in mitigating the transmission of syphilis. However, it might lead to increase of HIV cases. The results derived here could be adapted to other multi-disease scenarios in other regions.

PMID:36735105 | DOI:10.1007/s11538-023-01123-w

Trop Anim Health Prod. 2023 Feb 3;55(2):64. doi: 10.1007/s11250-023-03488-5.

ABSTRACT

The objective of this study was to understand and predict the intake and performance of Nellore cattle finished in the feedlot. Individual data from 144 non-castrated male Nellore steers finished in the feedlot between the years 2016 and 2020 were used. Descriptive statistical analyses and Pearson’s correlation were performed. The outliers were tested by evaluating the studentized residuals in relation to the values predicted by the equations. Residues that were outside the range of – 2.5 to 2.5 were removed. The goodness of fit of the developed equations was evaluated by the coefficients of determination (r²) and root mean square error (RMSE). The mean dry matter intake (DMI) was 10.2 kg/day, neutral detergent fiber intake (NDFI) was 3.4 kg/day, corresponding to 33.3% of DMI, crude protein intake (CPI) was 1.6 kg/day, and total digestible nutrient intake (TDNI) was 7.1 kg/day. The CPI to ADG ratio was 1.3 kg CPI/kg ADG and the TDNI to CPI ratio was 4.5 kg TDNI/kg CPI. The averages of productive performance were 1.3 kg/day for average daily gain (ADG), 152.6 kg for total weight gain (TWG), and 497.8 kg for final body weight (FBW) in average days in the confinement of 115.7 days. The intake measures correlated significantly with the performance measures, except for carcass yield and days in the feedlot. TWG had a high positive correlation with ADG (r = 0.84), while FBW had a positive correlation (r = 0.86) with hot carcass weight (HCW). Measures of intake, performance, and days in the feedlot can be used as predictors of DMI, FBW, HCW, TWG, and ADG. The prediction equations had satisfactory precision and accuracy for non-castrated Nellore cattle finished in feedlot systems under tropical conditions.

PMID:36735099 | DOI:10.1007/s11250-023-03488-5

Environ Monit Assess. 2023 Feb 3;195(3):359. doi: 10.1007/s10661-023-10969-5.

ABSTRACT

Zinc (Zn) is an essential micronutrient for plants and an important component for maintaining soil quality. Commonly found in the soil due to anthropogenic activities, such as industrialization and application of organic waste as fertilizers, in high concentrations, Zn may induce soil toxicity, affecting important communities, such as edaphic fauna. Despite its high concentrations found in the environment, Zn bioavailability can be affected by the type of soil, organic matter content and pH. In this work, Zn had its toxicity evaluated in a natural tropical soil, sampled in São Paulo-Brazil, for two soil invertebrates (Folsomia candida, Enchytraeus crypticus) and two seeds (Lactuca sativa and Phaseolus vulgaris), through ecotoxicological tests. The invertebrate E. crypticus was exposed to Zn concentrations of 10.0 (T1); 100.0 (T2); 150.0 (T3); 200.0 (T4); 400.0 (T5) mg Zn kg^-1 of dry soil, while F. candida, L. sativa and P. vulgaris were exposed to Zn concentrations of 100.0; 200.0; 400.0; 800.0 (t6); 1600.0 (t7); and 2000.0 (t8) mg Zn kg^-1 of dry soil. The outcome evaluated were seed germination, for L. sativa and P. vulgaris, and reproduction, for F. candida and E. crypticus. The EC50 obtained for E. crypticus, F. candida, L. sativa, and P. vulgaris were 261.5, 1089.7, 898.5, and 954.5 mg Zn kg^-1 of dry soil, respectively, being E. crypticus the most sensitive organism, and only at the highest Zn’s concentrations the organisms’ reproduction and seeds’ germination showed a statistically significant inhibitory effect (p < 0.05). Therefore, this work’s results showed that Zn does not present significant toxicity for the tested soil organisms and seeds and that at 100 mg Zn kg^-1 of dry soil it can be beneficial to F. candida and E. crypticus’ reproduction and L. sativa’s germination. These results imply that the presence of Zn in low concentrations, both in soil and biofertilizers, such as sewage sludge, not only is not a concern, but it can even benefit certain crops and functions of edaphic organisms, which may contribute to the engagement of sustainable agricultural practices and the quest for food security.

PMID:36735091 | DOI:10.1007/s10661-023-10969-5

J Forensic Sci. 2023 Feb 3. doi: 10.1111/1556-4029.15206. Online ahead of print.

ABSTRACT

TASER® weapons are conducted energy weapons (CEWs) that are frequently used by police departments around the world. CEWs can be deployed in two methods: drive stun application and probe deployment. This study aims to examine damages caused by TASER devices on fabrics and whether types of fabric material and TASER models could contribute to different damage features. Three types of white fabric were used, including 100% cotton, 100% polyester, and 65:35 polyester-cotton blend. Three models: TASER X26P, TASER X2, and TASER 7 were shot onto each type of fabric, with five repetitions each. Each damaged area on the fabric caused by a probe is a sample (n = 90) and was examined with a Keyence digital microscope. Images were captured by the Keyence microscope and measurements were recorded, including damage dimensions, fabric condition, evidence of burning, and extra findings. The presence of fused yarn ends was found to be statistically significant across the fabric types, and no damage features were found that may assist in the identification of TASER models. Other damage features including damage dimensions, discoloration, and fiber deformation were not found to be showing apparent differences according to statistical analysis. The conclusions made by this research should be used with caution due to the small sample size.

PMID:36734305 | DOI:10.1111/1556-4029.15206

Database (Oxford). 2023 Feb 3;2023:baac108. doi: 10.1093/database/baac108.

ABSTRACT

This study presents the outcomes of the shared task competition BioCreative VII (Task 3) focusing on the extraction of medication names from a Twitter user’s publicly available tweets (the user’s ‘timeline’). In general, detecting health-related tweets is notoriously challenging for natural language processing tools. The main challenge, aside from the informality of the language used, is that people tweet about any and all topics, and most of their tweets are not related to health. Thus, finding those tweets in a user’s timeline that mention specific health-related concepts such as medications requires addressing extreme imbalance. Task 3 called for detecting tweets in a user’s timeline that mentions a medication name and, for each detected mention, extracting its span. The organizers made available a corpus consisting of 182 049 tweets publicly posted by 212 Twitter users with all medication mentions manually annotated. The corpus exhibits the natural distribution of positive tweets, with only 442 tweets (0.2%) mentioning a medication. This task was an opportunity for participants to evaluate methods that are robust to class imbalance beyond the simple lexical match. A total of 65 teams registered, and 16 teams submitted a system run. This study summarizes the corpus created by the organizers and the approaches taken by the participating teams for this challenge. The corpus is freely available at https://biocreative.bioinformatics.udel.edu/tasks/biocreative-vii/track-3/. The methods and the results of the competing systems are analyzed with a focus on the approaches taken for learning from class-imbalanced data.

PMID:36734300 | DOI:10.1093/database/baac108

Psychophysiology. 2023 Feb 3:e14256. doi: 10.1111/psyp.14256. Online ahead of print.

ABSTRACT

Pupillometry has a rich history in the study of perception and cognition. One perennial challenge is that the magnitude of the task-evoked pupil response diminishes over the course of an experiment, a phenomenon we refer to as a fatigue effect. Reducing fatigue effects may improve sensitivity to task effects and reduce the likelihood of confounds due to systematic physiological changes over time. In this paper, we investigated the degree to which fatigue effects could be ameliorated by experimenter intervention. In Experiment 1, we assigned participants to one of three groups-no breaks, kinetic breaks (playing with toys, but no social interaction), or chatting with a research assistant-and compared the pupil response across conditions. In Experiment 2, we additionally tested the effect of researcher observation. Only breaks including social interaction significantly reduced the fatigue of the pupil response across trials. However, in all conditions we found robust evidence for fatigue effects: that is, regardless of protocol, the task-evoked pupil response was substantially diminished (at least 60%) over the duration of the experiment. We account for the variance of fatigue effects in our pupillometry data using multiple common statistical modeling approaches (e.g., linear mixed-effects models of peak, mean, and baseline pupil diameters, as well as growth curve models of time-course data). We conclude that pupil attenuation is a predictable phenomenon that should be accommodated in our experimental designs and statistical models.

PMID:36734299 | DOI:10.1111/psyp.14256

Hand (N Y). 2023 Feb 3:15589447221150510. doi: 10.1177/15589447221150510. Online ahead of print.

ABSTRACT

BACKGROUND: The purpose of this study was to examine the clinical outcomes of extensor tendon repairs based on zone of injury.

METHODS: A retrospective chart review was conducted on all patients who underwent primary extensor tendon repair at our institution. Extensor tendon repairs were performed using a multiple figure-of-8 suture technique for extensor zones 1-4 and a modified Kessler suture technique for extensor zones 5-8. Inclusion criteria included a minimum of 8 weeks of follow-up, complete data available for review, and extensor tendon injury requiring primary surgical repair.

RESULTS: A total of 132 digits were included for analysis: 46 digits in zones 1-4 and 86 digits in zones 5-8. The operative time for zone 1-4 injuries averaged 88.96 minutes, and the operative time for zone 5-8 injuries averaged 114.42 minutes. Final extension was found to be 2.33° for zones 1-4 and 6.66° for zones 5-8. Final flexion was found to be 141.4° for zones 1-4 and 195.3° for zones 5-8. There was 1 infection identified in zones 1-4 and 7 in zones 5-8.

CONCLUSIONS: Surgically repaired extensor tendons in zones 1-4 were found to have a statistically significant worse final flexion compared with surgically repaired extensor tendons in zones 5-8. No significant differences were found in final extension, complication rates, and time to full activity. Operative times for zone 5-8 tendon repairs were found to be significantly longer than operative times for zone 1-4 repairs, possibly due to more complex injury patterns seen in the more proximal zones.

PMID:36734256 | DOI:10.1177/15589447221150510

Physiother Theory Pract. 2023 Feb 3:1-7. doi: 10.1080/09593985.2023.2172703. Online ahead of print.

ABSTRACT

BACKGROUND: Previous studies reported inconsistent outcomes on elastic taping for three potential reasons: 1) poor control of placebo effect; 2) no consensus regarding the optimal tape tension; and 3) lack of investigation on muscle endurance, as the proposed tape recoiling force may not promote peak force generation but exert a consistently low force and improve submaximal contraction.

PURPOSE: This study compared the effects of elastic tape and its tension on muscle activity and endurance in people with extremely positive and negative personal belief on elastic tape.

METHODS: Using a validated instrument, we identified 20 participants with extremely positive personal belief on elastic tape (+ belief), and 20 with extremely negative personal belief (- belief). They performed wrist isometric endurance tests under three taping conditions (i.e. no tape, 50%, and 100% tension). We measured isometric wrist extensor muscle endurance, electromyography muscle activity, and self-perceived performance for each condition.

RESULTS: The differences between the two groups in isometric muscle endurance (p = .85) and muscle activity (p = .53) were not statistically significant, regardless of tape conditions. However, participants with + belief reported better perceived performance than those with – belief (p < .001, partial eta squared = 0.70). Specifically, 100% tape tension yielded stronger self-perceived performance than 50% tension (Cohen’s d = 0.91) and no tape (Cohen’s d = 1.86). On the other hand, participants with – belief perceived similar performance across tape tensions (p = .55).

CONCLUSION: Elastic tape does not modulate muscle activity and enhance muscle endurance. People with a strong positive personal belief on elastic tape may perceive a better performance with a greater tape tension.

PMID:36734244 | DOI:10.1080/09593985.2023.2172703

Int J Soc Psychiatry. 2023 Feb 3:207640231152208. doi: 10.1177/00207640231152208. Online ahead of print.

ABSTRACT

BACKGROUND: There are growing concerns about the homeless and mental health issues globally. This study aims to examine the mental health situation of homelessness and the determinants of anxiety and depression of them in Hong Kong.

METHOD: The data from the largest territory-wide study of the homeless population in 2021 was analyzed. Descriptive statistics and logistic regressions were used to investigate the association between mental health and socioeconomic variables, including demographic background, economic indicators, COVID-19 worries, government measures, and respect by others. The symptoms of depression and anxiety were assessed using Patient Health Questionnaire (PHQ) and General Anxiety Disorder (GAD).

RESULTS: The results showed that being female, food insecurity, and chronic diseases were the risk factors for anxiety and depression. A high level of respect by others was the protective factor for depression (adjusted OR 0.37, 95% CI [0.23, 0.61]) and anxiety (adjusted OR 0.40, 95% CI [0.24, 0.68]), compared to a low level of respect in the multivariate model.

CONCLUSIONS: Providing medical outreach services, additional resources for social services, implementation of homeless-friendly policies, and a progressive supply of public and transitional housing would help enhance the well-being of the homeless population.

PMID:36734241 | DOI:10.1177/00207640231152208

Stroke. 2023 Feb 3. doi: 10.1161/STROKEAHA.122.039900. Online ahead of print.

ABSTRACT

BACKGROUND: The effectiveness of long-term dual antiplatelet therapy (DAPT) to prevent recurrent strokes in patients with lacunar stroke remains unclarified. Therefore, this study aimed to compare and to elucidate the safety and effectiveness of DAPT and single antiplatelet therapy (SAPT) in preventing recurrence in chronic lacunar stroke.

METHODS: CSPS.com (Cilostazol Stroke Prevention Study for Antiplatelet Combination) was a prospective, multicenter, randomized controlled trial. In this prespecified subanalysis, 925 patients (mean age, 69.5 years; 69.4% men) with lacunar stroke were selected from 1884 patients with high-risk noncardioembolic stroke, enrolled in the CSPS.com trial after 8 to 180 days following stroke. Patients were randomly assigned to receive either SAPT or DAPT using cilostazol and were followed for 0.5 to 3.5 years. The primary efficacy outcome was the first recurrence of ischemic stroke. The safety outcomes were severe or life-threatening bleeding.

RESULTS: The DAPT group receiving cilostazol and either aspirin or clopidogrel and SAPT group receiving aspirin or clopidogrel alone comprised 464 (50.2%) and 461 (49.8%) patients, respectively. Ischemic stroke occurred in 12 of 464 patients (1.84 per 100 patient-years) in the DAPT group and 31 of 461 patients (4.42 per 100 patient-years) in the SAPT group, during follow-up. After adjusting for multiple potential confounding factors, ischemic stroke risk was significantly lower in the DAPT group than in the SAPT group (hazard ratio, 0.43 [95% CI, 0.22-0.84]). The rate of severe or life-threatening hemorrhage did not differ significantly between the groups (2 patients [0.31 per 100 patient-years] versus 6 patients [0.86 per 100 patient-years] in the DAPT and SAPT groups, respectively; hazard ratio, 0.36 [95% CI, 0.07-1.81]).

CONCLUSIONS: In patients with lacunar stroke, DAPT using cilostazol had significant benefits in reducing recurrent ischemic stroke incidence compared with SAPT without increasing the risk of severe or life-threatening bleeding.

REGISTRATION: URL: https://www.

CLINICALTRIALS: gov; Unique identifier: NCT01995370. URL: https://www.umin.ac.jp/ctr; Unique identifier: UMIN000012180.

PMID:36734235 | DOI:10.1161/STROKEAHA.122.039900