Tag: statistics

J Gen Intern Med. 2023 Mar 3. doi: 10.1007/s11606-023-08094-7. Online ahead of print.

ABSTRACT

BACKGROUND: Habitually skipping breakfast may promote the initiation and progression of gastrointestinal (GI) cancers, which have never been systematically explored in large-scale prospective studies.

METHODS: We prospectively examined the effects of breakfast frequency on the occurrence of GI cancers among 62,746 participants. The hazard ratios (HRs) and 95% confidence intervals (95% CIs) of GI cancers were calculated by Cox regression. The CAUSALMED procedure was used to perform the mediation analyses.

RESULTS: During a median follow-up of 5.61 (5.18 ~ 6.08) years, 369 incident GI cancer cases were identified. Participants who consumed 1-2 times breakfasts per week exhibited an increased risk of stomach (HR = 3.45, 95% CI: 1.06-11.20) and liver cancer (HR = 3.42, 95% CI: 1.22-9.53). Participants who did not eat breakfast had an elevated risk of esophageal (HR = 2.72, 95% CI: 1.05-7.03), colorectal (HR = 2.32, 95% CI: 1.34-4.01), liver (HR = 2.41, 95% CI: 1.23-4.71), gallbladder, and extrahepatic bile duct cancer (HR = 5.43, 95% CI: 1.34-21.93). In the mediation effect analyses, BMI, CRP, and TyG (fasting triglyceride-glucose) index did not mediate the association between breakfast frequency and the risk of GI cancer incidence (all P for mediation effect > 0.05).

CONCLUSIONS: Habitually skipping breakfast was associated with a greater risk of GI cancers including esophageal, gastric, colorectal, liver, gallbladder, and extrahepatic bile duct cancer.

TRIAL REGISTRATION: Kailuan study, ChiCTR-TNRC-11001489. Registered 24 August, 2011-Retrospectively registered, http://www.chictr.org.cn/showprojen.aspx?proj=8050.

PMID:36869181 | DOI:10.1007/s11606-023-08094-7

Sleep Breath. 2023 Mar 4. doi: 10.1007/s11325-023-02798-0. Online ahead of print.

ABSTRACT

PURPOSE: The relationships between sleep quality and sleep hygiene awareness in the Chinese population were unclear. We aimed to investigate the associations and related factors between sleep quality and sleep hygiene awareness in adults and to identify the most central domain for sleep quality using network analysis.

METHODS: A cross-sectional survey was conducted from April 22 to May 5, 2020. Adults (18 years old or above) who had access to smartphones were invited to participate in this survey. The Pittsburg Sleep Quality Index (PSQI) and the Sleep Hygiene Awareness and Practice Scale (SHAPS) were used to evaluate the sleep quality and sleep hygiene awareness of the participants. Propensity score matching (PSM) was used as sensitivity analysis to reduce the confounding effects. Multiple logistic regression was performed to evaluate the associations. The R packages “bootnet” and “qgraph” were used to estimate the connection and calculate the network centrality indices between good and poor sleepers.

RESULTS: In total, 939 respondents were included in the analysis. Of them, 48.8% (95% CI: 45.6-52.0%) were identified as poor sleepers. Participants with nervous system diseases, psychiatric diseases, and psychological problems were more likely to have poor sleep quality. The notion that using sleep medication regularly was beneficial to sleep was associated with poor sleep quality. Similarly, the notion that waking up at the same time each day disrupted sleep was also associated with poor sleep quality. The findings were consistent before and after PSM. Subjective sleep quality was the most central domain for sleep quality in good and poor sleepers.

CONCLUSION: Poor sleep quality was positively associated with certain sleep hygiene notions in Chinese adults. Effective measures such as self-relief, sleep hygiene education, and cognitive behavioral treatment may have been needed to improve sleep quality, especially during the COVID-19 outbreak.

PMID:36869169 | DOI:10.1007/s11325-023-02798-0

JCO Oncol Pract. 2023 Mar 3:OP2200341. doi: 10.1200/OP.22.00341. Online ahead of print.

ABSTRACT

PURPOSE: Despite more than a decade of endorsement from multiple international cancer authorities advocating all women with ovarian cancer be offered germline breast cancer (BRCA) gene testing, British Columbia Cancer Victoria was not meeting this target. A quality improvement project was undertaken with the aim of increasing completed BRCA testing rates for all eligible patients seen at British Columbia Cancer Victoria to > 90% by 1 year from April 2016.

METHODS: A current state analysis was completed, and multiple change ideas were developed, including education of medical oncologists, referral process update, initiating a group consenting seminar, and engagement of a nurse practitioner to lead the seminar. We used a retrospective chart audit from December 2014 to February 2018. On April 15, 2016, we initiated our Plan, Do, Study, Act (PDSA) cycles and completed them on February 28, 2018. We evaluated sustainability through an additional retrospective chart audit from January 2021 to August 2021.

RESULTS: Patients with completed germline BRCA genetic testing climbed from an average of 58%-89% per month. Before our project, patients waited on average 243 days (± 214) for their genetic test results. After implementation, patients received results within 118 days (± 98). This was sustained with an average of 83% of patients per month having completed germline BRCA testing almost 3 years after project completion.

CONCLUSION: Our quality improvement initiative resulted in a sustained increase in germline BRCA test completion for eligible patients with ovarian cancer.

PMID:36867837 | DOI:10.1200/OP.22.00341

Phys Rev Lett. 2023 Feb 17;130(7):071802. doi: 10.1103/PhysRevLett.130.071802.

ABSTRACT

An absolute measurement of the Λ_{c}^{+} lifetime is reported using Λ_{c}^{+}→pK^{-}π^{+} decays in events reconstructed from data collected by the Belle II experiment at the SuperKEKB asymmetric-energy electron-positron collider. The total integrated luminosity of the data sample, which was collected at center-of-mass energies at or near the ϒ(4S) resonance, is 207.2 fb^{-1}. The result, τ(Λ_{c}^{+})=203.20±0.89±0.77 fs, where the first uncertainty is statistical and the second systematic, is the most precise measurement to date and is consistent with previous determinations.

PMID:36867815 | DOI:10.1103/PhysRevLett.130.071802

Invest Educ Enferm. 2022 Oct;40(3). doi: 10.17533/udea.iee.v40n3e11.

ABSTRACT

OBJECTIVES: To evaluate the effectiveness of the application of an educational program based on the Health Belief Model (HBM) in Adopting Preventive Behaviors from Self-Medication among Women in Iran.

METHODS: Interventional study with pre and post phases. 200 women referring to the health centers of Urmia were selected by simple random sampling, divided into two groups of treatment and control. Data collection instruments were researcher-devised questionnaire including the questionnaire of Knowledge of Self-medication, the Questionnaire of Preventive Behaviors from Self-medication, and the questionnaire of Health Belief Model. The questionnaires were assessed for expert validity and then, were checked for reliability. The educational intervention was conducted for the treatment group during four weeks four 45-minute sessions.

RESULTS: The average scores of knowledge, perceived susceptibility, perceived severity, perceived benefits, perceived barriers, cues to action, self-efficiency, and post-intervention performance in have increased in treatment group, comparing to the control group, All findings were statistically significant (p < 0.05). Furthermore, social media, doctors, and disbelief in self-medication were more effective in increasing awareness and encouraging to have proper medication, also, the highest self-medication was in taking pain-relievers, cold tablets and antibiotics, which showed significant decrease in treatment group after the intervention.

CONCLUSIONS: The educational program based on Health Belief Model was effective in reducing the self-medication among the studied women. Furthermore, it is recommended to use social media and doctors to improve the awareness and motivation among people. Thus, applying the educational programs and plans according to the Health Belief Model can be influential in reducing the self-medication.

PMID:36867784 | DOI:10.17533/udea.iee.v40n3e11

Invest Educ Enferm. 2022 Oct;40(1). doi: 10.17533/udea.iee.v40n3e10.

ABSTRACT

OBJECTIVES: The work sought to determine the effect of the risk factors, fear, and concern on self-care regarding COVID-19 in people in pre-elderly and elderly stages.

METHODS: Correlational-predictive study, gathered through convenience sampling. The study applied the scale of fear of COVID-19 (Huarcaya et al.), the scale of concern about COVID-19 (Ruíz et al.,), and the scale of self-care during the COVID-19 confinement (Martínez et al.,). Descriptive and inferential statistics were applied as the mediation model based on regression.

RESULTS: The study had the participation of 333 people, with the majority being women (73.9%). Correlation was found between self-care with the scores from the scale of fear (r = -0.133, p <0.05) and of concern (r = -0.141, p<0.05) regarding COVID-19. The direct effect of the model was c= 0.16, [95% BCa CI = -0.28, -0.09]. The standardized value for the indirect effect was estimated as c = -0.14, [95% BCa CI= -0.23,-0.09]), which shows existence of a 14.0% effect of the mediating variable on self-care conducts in the prediction model.

CONCLUSIONS: A direct effect exists of risk factors for COVID-19 complication on self-care, mediated by concern and fear, besides explaining by 14% the self-care conducts for COVID-19. Recommendation is made to address other emotional variables to consider if these increase the prediction.

PMID:36867783 | DOI:10.17533/udea.iee.v40n3e10

Invest Educ Enferm. 2022 Oct;40(3). doi: 10.17533/udea.iee.v40n3e09.

ABSTRACT

OBJECTIVES: To identify and map the types of analysis in nursing validation studies.

METHODS: This is a scoping review with collection carried out in July 2020. The following data extraction indicators were considered: year of publication, country of origin, type of study, level of evidence, scientific references for validation and types of analyses. Data were collected in the following bases: U.S. National Library of Medicine, Cumulative Index to Nursing and Allied Health Literature, SCOPUS, COCHRANE, Web of Science, PSYCHINFO, Latin American and Caribbean Literature in Health Sciences, CAPES Theses and Dissertation Portal, Education Resources Information Center, The National Library of Australia’s Trobe, Academic Archive Online, DART-Europe E-Theses Portal, Electronic Theses Online Service, Open Access Scientific Repository of Portugal, National ETD Portal, Theses Canada, Theses and dissertations from Latin America.

RESULTS: The sample consisted of 881 studies, with a predominance of articles (841; 95.5%), with a prevalence of publications in 2019 (152;17.2%), of Brazilian origin (377; 42.8%), of the methodological study type (352; 39.9%). Polit and Beck stood out as the methodological reference (207; 23.5%) and Cronbach’s Alpha (421; 47.8%) as the statistical test. Regarding the type of analysis, the exploratory factor analysis and the content validation index stood out.

CONCLUSIONS: The use of at least one method of analysis was evident in more than half of the studies, which implied the need to carry out several statistical tests in order to evaluate the validation of the instrument used and show its reliability.

PMID:36867782 | DOI:10.17533/udea.iee.v40n3e09

Invest Educ Enferm. 2023 Oct;40(3). doi: 10.17533/udea.iee.v40n3e04.

ABSTRACT

OBJECTIVES: This work sought to characterize the primary care nursing consultation services reported in the official systemsof health services records in Colombia between 2002 and 2020.

METHODS: This was a descriptive, cross-sectional, retrospective study. Node geographic analysis and descriptive statistics were performed for quantitative data from the Special Registry of Health Providers and the Ministry of Health and Social Protection.

RESULTS: The study identified 6079 nursing services of which 72% are outpatient, 95.05% are assigned to institutions providing health services, 99.75% are of low complexity, and 48.22% of the offer was created in the last five years. The nodes with the highest increase in the offer of services are Caribbean (n = 909) and Pacific (n = 499), while Amazon (n = 48) showed the lowest offer in the last five years.

CONCLUSIONS: Disparity is evident in the availability of services by region and node, in addition to a low liberal exercise to provide nursing care.

PMID:36867777 | DOI:10.17533/udea.iee.v40n3e04

J Phys Chem A. 2023 Mar 3. doi: 10.1021/acs.jpca.2c07715. Online ahead of print.

ABSTRACT

Kinetic compensation is a strong, positive correlation between the Arrhenius activation energy E and the frequency factor A for a reaction between the same reactants under similar experimental conditions or similar reactants under the same conditions, even though these parameters are supposed to be independent. The kinetic compensation effect (KCE) is demonstrated by a linear relationship between ln[A] and E/R in the eponymous Constable plot and has been the subject of more than 50 000 publications over the past 100 years, with no consensus opinion about the cause of this effect. In this paper, it is suggested that the linear relationship between ln[A] and E is the result of a real or spurious path dependence of the reaction history between the initial state of the pure reactant(s) and the final state of the pure product(s) having standard enthalpy and entropy differences, ΔH° and ΔS°, respectively. The single-step rate law approximation of a reversible reaction leads to T₀ = H°/ΔS° as the dynamic thermal (thermodynamic) equilibrium temperature and 1/T₀ = (ln[A̅/k₀])/(E̅/R) as the slope of a Constable/KCE plot or the crossover temperature of Arrhenius lines in an isokinetic relationship (IKR), where A̅ and E̅ are mean values for the ensemble of compensating {E_i, A_i} pairs and k₀ is a constant that accounts for the path dependence of the reaction history and reconciles the KCE with the IKR. This proposed physical basis for the KCE and IKR is supported by qualitative agreement between ΔH° and ΔS° calculated from the statistics of compensating {E_i, A_i} pairs in the literature, and the difference in the standard enthalpies and entropies of formation of the products and reactants for thermal decomposition of organic peroxides, calcium carbonate, and poly(methyl methacrylate).

PMID:36867752 | DOI:10.1021/acs.jpca.2c07715

Eur J Psychotraumatol. 2022 Dec;13(2):2151097. doi: 10.1080/20008066.2022.2151097.

ABSTRACT

Background: A burn event can elicit symptoms of posttraumatic stress disorder (PTSD) in survivors and their partners and may impact the way these couple members interact with each other. They may try to protect each other from further emotional distress by avoiding talking about the burn event, but they may also show concern towards each other.Objective: The aim of this study was to investigate bidirectional relationships between survivor’s and partner’s PTSD symptoms and two interpersonal processes: partner-oriented ‘self-regulation’, which is avoidance-oriented, and ‘expressed concern’, which is approach-oriented.Method: In this longitudinal multi-centre study, 119 burn survivors and their partners participated. Measures of PTSD symptoms, self-regulation, and expressed concern were administered in the acute phase following the burns, and follow-ups took place up to 18 months postburn. Intra- and interpersonal effects were examined in a random intercept cross-lagged panel model. Exploratory effects of burn severity were also investigated.Results: Within individuals, survivor’s expressed concern predicted later higher levels of survivor’s PTSD symptoms. In their partners, self-regulation and PTSD symptoms reinforced each other in the early phase postburn. Between the two couple members, partner’s expressed concern predicted later lower levels of survivor’s PTSD symptoms. Exploratory regression analyses showed that burn severity moderated the effect of survivor’s self-regulation on survivor’s PTSD symptoms, indicating that self-regulation was continuously related to higher levels of PTSD symptoms over time within more severely burned survivors, but not in less severely burned survivors.Conclusion: PTSD symptoms and self-regulation reinforced each other in partners and possibly also in more severely burned survivors. Partner’s expressed concern was related to lower levels of survivor’s PTSD symptoms, whereas survivor’s expressed concern was related to higher levels of survivor’s PTSD symptoms. These findings emphasize the importance of screening for and monitoring PTSD symptoms in burn survivors and their partner and of encouraging couple’s self-disclosure.

PMID:36867741 | DOI:10.1080/20008066.2022.2151097