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Nevin Manimala Statistics

A Bayesian perspective on severity: risky predictions and specific hypotheses

Psychon Bull Rev. 2022 Aug 15. doi: 10.3758/s13423-022-02069-1. Online ahead of print.

ABSTRACT

A tradition that goes back to Sir Karl R. Popper assesses the value of a statistical test primarily by its severity: was there an honest and stringent attempt to prove the tested hypothesis wrong? For “error statisticians” such as Mayo (1996, 2018), and frequentists more generally, severity is a key virtue in hypothesis tests. Conversely, failure to incorporate severity into statistical inference, as allegedly happens in Bayesian inference, counts as a major methodological shortcoming. Our paper pursues a double goal: First, we argue that the error-statistical explication of severity has substantive drawbacks; specifically, the neglect of research context and the specificity of the predictions of the hypothesis. Second, we argue that severity matters for Bayesian inference via the value of specific, risky predictions: severity boosts the expected evidential value of a Bayesian hypothesis test. We illustrate severity-based reasoning in Bayesian statistics by means of a practical example and discuss its advantages and potential drawbacks.

PMID:35969359 | DOI:10.3758/s13423-022-02069-1

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Nevin Manimala Statistics

Achievement of learning outcomes in non-traditional (online) versus traditional (face-to-face) Anatomy teaching in medical schools: A mixed method systematic review

Clin Anat. 2022 Aug 15. doi: 10.1002/ca.23942. Online ahead of print.

ABSTRACT

In recent years, the logistical challenges posed by the Covid-19 pandemic have prompted medical educators teaching gross anatomy to explore an expanded use of online instructional modalities. There is concern that this shift to online anatomy education in medical schools could affect long-term learning outcomes for future healthcare providers. In this systematic review, the educational effectiveness of online anatomy teaching is compared with traditional (“face-to-face”) teaching methods, specifically in terms of students’ academic performance and satisfaction. A search of four databases identified and screened one hundred and sixty-two studies. Subsequently, thirty-one studies were analyzed, including both (a) teaching outcome measures (test scores) and (b) student satisfaction ratings. Authors chose studies, extracted data, assessed quality and examined risk of bias. Nineteen studies compared students’ academic performances between online and face-to-face teaching methods. Twenty-six studies measured students’ levels of satisfaction in both teaching methods. Both qualitative and quantitative analyses of the data revealed comparable academic performances with no statistical difference between the two teaching methods, but a higher level of satisfaction with face-to-face teaching. The findings confirm that students can learn from online teaching but are more satisfied with face-to-face teaching. The authors conclude that online teaching cannot replace traditional teaching and there is no preference for one type of modality over the other. Therefore, a multi-modal learning approach combining online with face-to-face educational modalities for medical students could be efficient and successful.

PMID:35969356 | DOI:10.1002/ca.23942

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Nevin Manimala Statistics

The sociodemographic characteristics and social determinants of visual impairment in a homeless population in the Montreal area

Can J Public Health. 2022 Aug 15. doi: 10.17269/s41997-022-00676-y. Online ahead of print.

ABSTRACT

OBJECTIVE: Homelessness is a serious social and public health concern in Canada. Individuals experiencing homelessness face numerous health problems and barriers in accessing health services. Visual impairment can exacerbate the lower quality of life experienced by people who are homeless, but its incidence among this population has been poorly documented in the literature. Our study aimed to describe health and sociodemographic characteristics and determine their association with visual impairment, ocular pathology and uncorrected refractive errors in a homeless population in Montreal, Canada.

METHODS: This cross-sectional study was conducted between May 2019 and September 2020 in eight homeless shelters selected using a stratified random sampling approach on the island of Montreal. An eye examination was performed on all participants, who were also administered a survey on social determinants of health. Descriptive analysis was used to analyze survey data, and logistic regression was used for each of the three study outcomes.

RESULTS: A total of 124 individuals experiencing homelessness (93 men, 31 women) were recruited. Participants were mostly Caucasian (> 70%) with an average age of 48 years (standard deviation = 13 years). Our sample reported a high level of education (68% had a high school diploma or higher), a high level of health insurance coverage (77%), social assistance benefits (71%), and social support (over 50%). There was a high prevalence of chronic conditions including diabetes (14%), hypertension (25%), and HIV/AIDS (3%). Results from eye examinations showed a high prevalence of visual impairment (22%), ocular pathology (23%), and uncorrected refractive error (75%). Age was statistically significantly associated with each outcome variable.

CONCLUSION: Despite a high level of social and health support, individuals experiencing homelessness in Montreal, Canada, experience high levels of chronic conditions and visual impairment. Our study highlights the unmet need for eye healthcare among homeless populations, and that eye health can be a unique entry point for intervening with homeless populations.

PMID:35969355 | DOI:10.17269/s41997-022-00676-y

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Nevin Manimala Statistics

Effect of the COVID-19 pandemic on the socioeconomic composition of emergency department presentations

Can J Public Health. 2022 Aug 15. doi: 10.17269/s41997-022-00684-y. Online ahead of print.

ABSTRACT

OBJECTIVES: This study highlights how socioeconomic trends in the emergency department (ED) for low-acuity visits change with the onset of COVID-19, identifies societal inequities exacerbated by the pandemic, and demonstrates the geographical regions where these inequities occur.

METHODS: We accessed 1,285,000 ED visits from 12 different facilities across New Brunswick from January 2017 to October 2020. Using a deprivation index developed by Statistics Canada as a measure of socioeconomic status, and controlling for additional factors, we perform a logistic regression to determine the influence of the COVID-19 pandemic on low-acuity visits of individuals from the most deprived quintile (Q5). We constructed a heat map of New Brunswick to highlight regions of high deprivation.

RESULTS: The proportion of Q5 individuals in the ethnocultural composition domain accessing the ED for low-acuity visits increased from 22.91% to 24.72% with the onset of the pandemic. Our logistic regression showed the log odds of being considered Q5 in the ethnocultural composition domain when visiting the ED for a low-acuity reason increased by 6.3% if the visit occurred during the pandemic, and increased by 101.6% if the visit occurred in one of the 3 major regions of New Brunswick.

CONCLUSION: Individuals visiting EDs for low-acuity reasons during the COVID-19 pandemic were more likely to be from the most diverse quintile in the ethnocultural domain, and the inequities were concentrated in the most urban regions in New Brunswick. This demonstrates that urban areas are where inequities are disproportionately faced for ethnically diverse individuals and demonstrates where policies could be focused.

PMID:35969354 | DOI:10.17269/s41997-022-00684-y

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Nevin Manimala Statistics

The nexus between environmental strategy and environmental performance: analyzing the roles of green product innovation and mechanistic/organic organizational structure

Environ Sci Pollut Res Int. 2022 Aug 15. doi: 10.1007/s11356-022-22489-9. Online ahead of print.

ABSTRACT

The relationship between environmental strategy and environmental performance has been extensively analyzed in the environmental management literature. However, this relationship is spurious due to the inconsistence outcomes, lack of intervening mechanism, and scarcity of appropriate context. This study undertakes these considerations by exploring the underlying moderation-mediation mechanism through which proactive corporate environmental strategy affects corporate environmental performance. The hypotheses of the study were empirically tested on the data gathered from 147 ISO 14001:2015 certified firms in Pakistan. The data was statistically validated and then tested with Bootstrapping method using Preacher and Hayes Process Macros. The findings of the study revealed that a proactive corporate environmental strategy predicts corporate environmental performance through green product innovation. Moreover, the moderation hypothesis of the organizational structure variable in the nexus between proactive corporate environmental strategy and green product innovation was not supported in the full sample, whereas the split sample based on organizational size indicated moderation effects in the small firm’s sample. The findings of the study carry important implications for firms related to corporate environmental strategy and green product innovation strategy.

PMID:35969346 | DOI:10.1007/s11356-022-22489-9

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Nevin Manimala Statistics

Fabrication and response optimization of Moringa oleifera-functionalized nanosorbents for the removal of diesel range organics from contaminated water

Environ Sci Pollut Res Int. 2022 Aug 15. doi: 10.1007/s11356-022-22245-z. Online ahead of print.

ABSTRACT

The purpose of this research is to synthesize environmentally friendly nanosorbents for the novel adsorption of diesel range organics (DRO) from contaminated water. Central composite design (CCD) analysis of response surface methodology (RSM) was employed in a model fitting of the variables predicting the adsorption efficiency of Moringa oleifera-functionalized zerovalent iron particles (ZINPs) for the removal of DRO. The effects of the reaction parameters on the response were screened using 24 factorial designs to determine the statistically significant independent variables. A quadratic model predicting the DRO adsorption efficiency of ZINPs with an F value of 276.84 (p value < 0.0001) was developed. Diagnostic plots show that the predicted values were in excellent agreement with actual experimental values (R2 = 0.99). The maximum percentage removal of DRO of 92.6% was achieved after optimization, using the synthesized ZINPs after 8 h of contact between DRO substrates and ZINPs at pH of 8, the temperature of 25 °C, with an adsorbent dosage of 2 g/L and at composite desirability of 1. Characterization of ZINPs revealed the formation of quasi nanospheres and nanocubes with an average particle diameter of 50.9 ± 9.7, a crystallite size of 15.31 nm, a crystallinity index of 32.47% and a pore width of 75.69-88.59 nm. The adsorption equilibrium data modelling of ZINPs for adsorption of DRO was best described by Langmuir isotherm with the maximum monolayer coverage capacity of 7.194 mg/g. The separation factor [Formula: see text], indicated favourable adsorption. The adsorption kinetic data were consistent with pseudo-second-order kinetics indicating probable chemisorption.

PMID:35969341 | DOI:10.1007/s11356-022-22245-z

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Nevin Manimala Statistics

Mediating role of physical activity in the relationship between exercise-induced muscle pain and symptom severity in women with fibromyalgia

Physiother Theory Pract. 2022 Aug 13:1-9. doi: 10.1080/09593985.2022.2111674. Online ahead of print.

ABSTRACT

BACKGROUND: Individuals with fibromyalgia (FM) exhibit generalized hyperalgesia to pain stimuli, and physical activity (PA) is critical to manage FM symptoms.

PURPOSE: This study examined the relationship between exercise-induced muscle pain, symptom severity, and PA in 28 women with FM.

METHODS: Muscle pain rating (MPR) was assessed during 3 minutes of submaximal isometric handgrip exercise, whereas PA and symptom severity were evaluated via self-report questionnaires. The analysis examined the relationship between the variables, with the specific interest in the mediating role of PA in the relationship between exercise-induced muscle pain and symptom severity.

RESULTS: MPR was positively associated with symptom severity (b = 1.89; 95% CI = 0.01, 3.76; P = .048) and inversely associated with PA levels (b = -0.16; 95% CI = -0.30, -0.03; P = .021). PA levels were inversely associated with symptom severity (b = -7.94; 95% CI = -12.46, -3.42; P = .001). After statistically controlling for PA levels, the relationship between MPR and symptom severity was no longer significant (b = 0.60; Wald 95% CI = -1.05, 2.25; P = .474).

CONCLUSION: Results show the link between the variables, and specifically demonstrate that PA mediates the relationship between exercise-induced muscle pain and symptom severity.

PMID:35968757 | DOI:10.1080/09593985.2022.2111674

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Nevin Manimala Statistics

Examination of Pandemic Awareness, Death Anxiety, and Spiritual Well-Being in Elderly Individuals

Omega (Westport). 2022 Aug 13:302228221120122. doi: 10.1177/00302228221120122. Online ahead of print.

ABSTRACT

This study aimed to examine the relationships between the variables of pandemic awareness, death anxiety, and spiritual well-being and reveal whether the participants’ perceptions of pandemic awareness, death anxiety, and spiritual well-being differed according to various sociodemographic characteristics. The study population is comprised of individuals aged 65 years and over in Edirne, Turkey. The data obtained from 449 people in the study were analyzed using various statistical methods. According to the results of the regression analysis performed in the study, the increase in the participants’ pandemic awareness was found to reduce their death anxiety and increase their spiritual well-being statistically. Moreover, the increase in the participants’ death anxiety statistically reduced their spiritual well-being.

PMID:35968726 | DOI:10.1177/00302228221120122

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Nevin Manimala Statistics

Accuracy of reverse-transcription polymerase chain reaction and loop-mediated isothermal amplification in diagnosing severe fever with thrombocytopenia syndrome: A systematic review and meta-analysis

J Med Virol. 2022 Aug 15. doi: 10.1002/jmv.28068. Online ahead of print.

ABSTRACT

BACKGROUND: Nucleic acid molecular diagnostic technology plays an important role in the detection of severe fever with thrombocytopenia syndrome (SFTS). However, no relevant reports have been published on the accuracy of reverse-transcription polymerase chain reaction (RT-PCR) and reverse-transcription loop-mediated isothermal amplification (RT-LAMP) in the diagnosis of SFTS. Thus, we conducted a meta-analysis and systematic review to evaluate the accuracy of the two methods.

METHODS: On June 19, 2022, we comprehensively searched the PubMed, Embase, Cochrane Library, Web of Science, Scoups, Ovid, Proquest, China National Knowledge Infrastructure Database, Wan Fang Data, Traditional Chinese Medicine Database (Sinomed), VIP Database and Reading Showing Database for articles on nucleic acid diagnostic techniques, such as RT-PCR and RT-LAMP, used to diagnose SFTS. Statistical analysis was performed using STATA 14.0 and Meta-Disc 1.4.

RESULTS: Sixteen articles involving 2942 clinical blood samples were included in the analysis. RT-PCR and RT-LAMP were used as index tests, whereas RT-PCR or other detection methods were used as reference standards. The pooled values for the sensitivity, specificity, positive and negative likelihood ratios of the RT-PCR test were 0.97 (95% CI: 0.92, 0.99), 1.00 (95% CI: 0.98, 1.00), 483.87 (95% CI: 58.04, 4033.76), and 0.03 (95% CI:0.01, 0.08) respectively. Those for the RT-LAMP test were 0.95 (95% CI: 0.91, 0.97), 0.99 (95% CI: 0.93, 1.00), 111.18 (95% CI: 13.96, 885.27), and 0.05 (95% CI: 0.03, 0.09), respectively.

CONCLUSION: Both RT-PCR and RT-LAMP have high diagnostic value in SFTS and can be applied in different scenarios for laboratory confirmation or on-site screening. This article is protected by copyright. All rights reserved.

PMID:35968756 | DOI:10.1002/jmv.28068

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Nevin Manimala Statistics

Effect of Palmar Grasp Reflex Stimulation on Physiological Parameters and Crying Time During Neonatal Bath: A Randomized Controlled Trial

Biol Res Nurs. 2022 Aug 13:10998004221113765. doi: 10.1177/10998004221113765. Online ahead of print.

ABSTRACT

OBJECTIVE: This study aimed to determine the effect of palmar grasp reflex stimulation during a neonatal bath on the physiological parameters and crying time of the newborn.

DESIGN, SETTING, AND PARTICIPANTS: This study was designed as a parallel randomized clinical trial. Parents fully understood the study procedure at the Neonatal Intensive Care Unit in Turkey (N = 82). Both written and verbal consent was obtained from the parents. Newborns who were ineligible for tub bathing were excluded from the study. The babies in the control group were given baths according to the tub bathing standards. Babies in the experimental group were given palmar grasp reflex stimulation during the baths. The variables examined included body temperature, respiratory rate, pulse, oxygen saturation levels, and crying time. In all analyses, p < 0.05 was accepted as statistically significant.

RESULTS: The heart rate of the experimental group was 5.2 beats per minute slower than the control group (χ2 = 12.272; p < 0.001). The respiratory rate of the experimental group was 1.3 lower per minute compared to the control group (χ2 = 43.219; p < 0.001). In addition, the oxygen saturation level (%) of the experimental group was 0.4 higher than the control group (χ2 = 5.793; p < 0.016). Crying time was higher in the control group during bathing (p < 0.001).

CONCLUSION: The results showed that the palmar grasp reflex in newborn bathing helps to maintain the stability of physiological parameters and shortens the crying time of babies. Palmar grasp reflex stimulation is recommended in interventions that may cause stress.

PMID:35968725 | DOI:10.1177/10998004221113765