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Nevin Manimala Statistics

Human-Altered Landscapes and Climate to Predict Human Infectious Disease Hotspots

Trop Med Infect Dis. 2022 Jul 1;7(7):124. doi: 10.3390/tropicalmed7070124.

ABSTRACT

BACKGROUND: Zoonotic diseases account for more than 70% of emerging infectious diseases (EIDs). Due to their increasing incidence and impact on global health and the economy, the emergence of zoonoses is a major public health challenge. Here, we use a biogeographic approach to predict future hotspots and determine the factors influencing disease emergence. We have focused on the following three viral disease groups of concern: Filoviridae, Coronaviridae, and Henipaviruses.

METHODS: We modelled presence-absence data in spatially explicit binomial and zero-inflation binomial logistic regressions with and without autoregression. Presence data were extracted from published studies for the three EID groups. Various environmental and demographical rasters were used to explain the distribution of the EIDs. True Skill Statistic and deviance parameters were used to compare the accuracy of the different models.

RESULTS: For each group of viruses, we were able to identify and map areas at high risk of disease emergence based on the spatial distribution of the disease reservoirs and hosts of the three viral groups. Common influencing factors of disease emergence were climatic covariates (minimum temperature and rainfall) and human-induced land modifications.

CONCLUSIONS: Using topographical, climatic, and previous disease outbreak reports, we can identify and predict future high-risk areas for disease emergence and their specific underlying human and environmental drivers. We suggest that such a predictive approach to EIDs should be carefully considered in the development of active surveillance systems for pathogen emergence and epidemics at local and global scales.

PMID:35878136 | DOI:10.3390/tropicalmed7070124

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Nevin Manimala Statistics

The Prevalence and Implications of Olfactory/Gustatory Dysfunctions among Adult COVID-19 Patients: A Retrospective Cohort Multiethnic Populations Study

Trop Med Infect Dis. 2022 Jun 23;7(7):115. doi: 10.3390/tropicalmed7070115.

ABSTRACT

(1) Background: Olfactory and gustatory dysfunctions (OGDs) was found in COVID-19 patients. Only a few studies looked into the prevalence of OGDs in the United Arab Emirates (UAE). The purpose of this study was to estimate the prevalence OGDs among multiethnic COVID-19 patients in the UAE, and its association to patients’ characteristics and disease outcomes; (2) Methods: There were 1785 COVID-19 patients included in our cohort; (3) Results: Males made up most of the study participants (86.3%). A total of 11.7% of the participants reported OGDs. Female gender and ethnicity had significantly higher symptom prevalence (p < 0.001). COVID-19 severity had a strong inverse association with OGDs (p = 0.007). Other illness outcomes, such as ICU admission, pneumonia development, and mortality, showed no correlation. Males, Asians, and patients with comorbidities all had statistically significantly lower prevalence odds. On the other hand, Emirati, Arab, and Iranian patients had a higher prevalence. COVID-19 patients with OGDs had a considerably shorter time until viral clearance than those without the symptom; (4) Conclusions: in nonsevere COVID-19, olfactory/gustatory dysfunction is common. As a result, it could be applied as a predictive sign for early disease diagnosis and prognosis.

PMID:35878127 | DOI:10.3390/tropicalmed7070115

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Nevin Manimala Statistics

Bayesian Network Analysis of Lymphatic Filariasis Serology from Myanmar Shows Benefit of Adding Antibody Testing to Post-MDA Surveillance

Trop Med Infect Dis. 2022 Jun 21;7(7):113. doi: 10.3390/tropicalmed7070113.

ABSTRACT

The elimination of lymphatic filariasis (LF) is achieved through repeated mass drug administration (MDA) of anti-filarial medications, which interrupts transmission and prevents new infections. Accurate transmission assessments are critical to deciding when to stop MDA. Current methods for evaluating transmission may be insufficiently sensitive, resulting in post-MDA resurgence. We, therefore, evaluated potential diagnostic testing scenarios for post-MDA surveillance. Data were used from two surveys (a household cluster and a cohort) conducted in an area of Mandalay Region, Myanmar, with ongoing transmission following several rounds of MDA. First, age- and sex-adjusted seroprevalence were estimated for the area using the household survey. Next, three Bayesian networks were built from the combined datasets to compare antigens by immunochromatic testing (ICT) and/or Og4C3 enzyme-linked immunosorbent assay (ELISA) and antibody (Ab) detection methods (Wb123 or Bm14 Ab ELISA). The networks were checked for validity and then used to compare diagnostic testing scenarios. The adjusted prevalence from the household survey for antigen, Wb123 Ab and Bm14 Ab were 4.4% (95% CI 2.6-7.3%), 8.7% (5.96-12.5%) and 20.8% (16.0-26.6%), respectively. For the three networks, the True Skill Statistic and Area Under the Receiver Operating Characteristic Curve for antigen, Wb123 and Bm14 Ab were 0.79, 0.68 and 0.55; and 0.97, 0.92 and 0.80, respectively. In the Bayesian network analysis, a positive case was defined as testing positive to one or more infection markers. A missed result was therefore the probability of a positive case having a negative test result to an alternate marker. The probability of a positive case prior to any testing scenario was 17.4%, 16.8% and 26.6% for antigen, Wb123 Ab and Bm14 Ab, respectively. In the antigen-only testing scenario, the probability of a missed positive LF result was 5.2% for Wb123 and 15.6% for Bm14 Ab. The combination of antigen plus Bm14 Ab testing reduced the probability of missing a positive LF case as measured by Wb123 Ab to 0.88%. The combination of antigen plus Wb123 Ab was less successful and yielded an 11.5% probability of a missed positive result by Bm14 Ab testing. Across scenarios, there was a greater discordance between Bm14 and both antigen and Wb123 Ab in the 1-10 age group compared to older ages. These findings suggest that the addition of Bm14 Ab improves the sensitivity of LF testing for current or past infection. The combination of antigen plus Bm14 Ab should therefore be considered for inclusion in post-MDA surveillance to improve the sensitivity of transmission surveys and prevent the premature cessation of MDA.

PMID:35878125 | DOI:10.3390/tropicalmed7070113

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Nevin Manimala Statistics

Morphological Characteristics and Situational Precision of U15 and U16 Elite Male Players from Al-Ahli Handball Club (Bahrein)

Sports (Basel). 2022 Jul 6;10(7):108. doi: 10.3390/sports10070108.

ABSTRACT

The aim of this cross-sectional study was to determine the differences in the morphological characteristics and situational precision among younger and older groups of handball players. The sample of participants consisted of 30 handball players, members of the younger category of the Al-Ahli handball club (Bahrein), divided into two groups: older (U16, n = 18) and younger (U15, n = 12). To evaluate their morphological characteristics, eight variables were measured, while two standardized tests were used to evaluate their situational precision. The results indicate that a statistically significant difference between the groups was noticeable for nine variables in total, seven in morphology (body height, p = 0.010; body mass index, p = 0.049; arm length, p = 0.009; upper arm length, p = 0.016; lower arm length, p = 0.040; the planimetric parameter of the hand, p = 0.005; hand length p = 0.004) and two in situational precision (the standing shot, p = 0.003; the jump shot, p = 0.17), and that the achieved difference ranges from a medium to a large effect. For only one variable (body mass, p = 0.734), significant difference was not determined between the groups. It was also determined (by Cohen’s criterion) that handball players with higher longitudinal dimensionality achieve better results for specific precision. Therefore, when selecting young handball players, the aforementioned dimensions should be taken into consideration as predictors of success.

PMID:35878119 | DOI:10.3390/sports10070108

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Nevin Manimala Statistics

Does Physical Activity in Natural Outdoor Environments Improve Wellbeing? A Meta-Analysis

Sports (Basel). 2022 Jun 29;10(7):103. doi: 10.3390/sports10070103.

ABSTRACT

Organizational initiatives and researchers have argued for the importance of the natural outdoor environment (NOE) for promoting wellbeing. The main aim of this meta-analysis was to synthesize the existing literature to examine the effects of physical activity (PA) in the NOE on wellbeing in adults. The secondary aim was to explore whether wellbeing reported by adults differs as a function of PA context. Electronic databases (PubMed, ProQuest Nursing and Allied Health, PsycINFO, SPORTDiscus and Embase) were searched for English peer-reviewed articles published before January 2019. Inclusion criteria were: (1) healthy adults; (2) PA in the NOE; (3) the measurement of wellbeing; and (4) randomized control trials, quasi-experimental designs, matched group designs. To address the secondary aim, PA in the NOE was compared with that performed indoors. Risk of bias was assessed through the Effective Public Health Practice Project (EHPP) Quality Assessment Tool for Quantitative Studies. Primary studies meeting inclusion criteria for the main (nstudies = 19) and secondary (nstudies = 5) aims were analyzed and interpreted. The overall effect size for the main analysis was moderate (d = 0.49, p < 0.001; 95% CI = 0.33, 0.66), with the magnitude of effect varying depending on wellbeing dimension. Wellbeing was greater in PA in the NOE subgroup (d = 0.53) when compared with the indoor subgroup (d = 0.28), albeit not statistically significant (p = 0.15). Although physical activity in the NOE was associated with higher wellbeing, there is limited evidence to support that it confers superior benefits to that engaged indoors. Researchers are encouraged to include study designs that measure markers of wellbeing at multiple time points, greater consideration to diverse wellbeing dimensions and justify decisions linked to PA and NOE types.

PMID:35878114 | DOI:10.3390/sports10070103

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Nevin Manimala Statistics

The Relative Age Effect in the Best Track and Field Athletes Aged 10 to 15 Years Old

Sports (Basel). 2022 Jun 28;10(7):101. doi: 10.3390/sports10070101.

ABSTRACT

(1) The purpose of this study was to examine the prevalence of the relative age effect (RAE) in the best young (10 to 15 years old) track and field athletes. (2) Hypothesis: The prevalence of the RAE in the best young track and field athletes of both genders will be evident in all age groups from 10 to 15 years old, which may be associated with the significant relationship between biological maturity, chronological age, and the development of physical qualities. (3) Materials and methods: In total, 1778 athletes volunteered for this study. The sample was based on the results of the best young athletes who participated in the final tournaments of the national competition “Shipovka Yunykh”(“Running spikes for young athletes”), which have been held since 1981. The sample group consisted of male and female athletes classified into specific age groups: 10 to 11 years old (n = 579), 12 to 13 years old (n = 600), and 14 to 15 years old (n = 599). Analysis was performed using Jamovi 1.8.1. The Chi-square test was used to compare the RAE between different groups. (4) Results: A wide distribution of the RAE was revealed both in the general sample and in boys and girls. The percentage of “early-born” athletes was 37.6% while only 12.3% were “late-born” athletes. The difference in the severity of the RAE may reflect the small sample of athletes from the fourth quartile, which was significantly less than the sample of boys from the fourth quartile (p = 0.04, OR 1.68, 95% CI 1.02-2.78). The RAE was also evident in all age groups of boys and girls, without any statistically significant differences in the severity (p > 0.05, Chi = 2.135, V = 0.02). In the 14- to 15-year-old male athletes group, the number of early-born compared to late-born athletes peaked. The RAE was most common amongst the most successful track and field athletes. Among the competition medalists during the analyzed time period, more than 50% of athletes were born in the first quarter and no athletes were born in the fourth quarter.

PMID:35878112 | DOI:10.3390/sports10070101

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Nevin Manimala Statistics

The effect of changing the military’s sexual assault laws on law enforcement investigative findings in the U.S. Army

Law Hum Behav. 2022 Aug;46(4):313-323. doi: 10.1037/lhb0000489.

ABSTRACT

OBJECTIVE: In 2007, Congress changed the military’s sexual assault laws as part of an effort to improve sexual assault case processing. This study looked at the U.S. Army law enforcement investigative finding for every sexual assault reported to the Army from 2004 through June 2012, along with every nonsexual assault. Our objective was to measure whether the legal intervention affected the investigative findings made by Army law enforcement officers in sexual assault cases (penetrative, nonpenetrative, and combined) as compared to assault cases (aggravated, simple, and combined).

HYPOTHESES: We hypothesized that we would not find evidence that the legal intervention affected the rate of sexual assault cases labeled as “founded” by Army law enforcement, such that for the best-fitting time-series models, any difference in the residuals of the means before and after the intervention would not be statistically significant.

METHOD: We received data from the U.S. Army on all sexual assaults and nonsexual assaults from 2004 through June 2012. The data comprised 47,058 observations. We used time-series analysis with autoregressive integrated moving average modeling. The variable tracked over time was the ratio of the proportion of founded sexual assault cases to the proportion of founded nonsexual assault cases. We then conducted t tests of the means of the residuals before and after the legal intervention.

RESULTS: The difference in the means of the residuals before and after the intervention was not statistically significant for combined sexual assaults versus combined assaults, penetrative sexual assaults versus aggravated assaults, or nonpenetrative sexual assaults versus simple assaults.

CONCLUSIONS: This reform to sexual assault laws does not appear to have affected sexual assault case processing by U.S. Army law enforcement. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

PMID:35878107 | DOI:10.1037/lhb0000489

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Nevin Manimala Statistics

Evaluation of the Adsorption Efficiency of Graphene Oxide Hydrogels in Wastewater Dye Removal: Application of Principal Component Analysis

Gels. 2022 Jul 18;8(7):447. doi: 10.3390/gels8070447.

ABSTRACT

Industrial dye wastewater is one of the major water pollution problems. Adsorbent materials are promising strategies for the removal of water dye contaminants. Herein, we provide a statistical and artificial intelligence study to evaluate the adsorption efficiency of graphene oxide-based hydrogels in wastewater dye removal by applying Principal Component Analysis (PCA). This study aims to assess the adsorption quality of 35 different hydrogels. We adopted different approaches and showed the pros and cons of each one of them. PCA showed that alginate graphene oxide-based hydrogel (without polyvinyl alcohol) had better tolerance in a basic medium and provided higher adsorption capacity. Polyvinyl alcohol sulfonated graphene oxide-based hydrogels are suitable when higher adsorbent doses are required. In conclusion, PCA represents a robust way to delineate factors affecting hydrogel selection for pollutant removal from aqueous solutions.

PMID:35877532 | DOI:10.3390/gels8070447

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Nevin Manimala Statistics

Risk factors for increased length of hospital stay among young pediatric patients who suffer facial fractures

Dent Traumatol. 2022 Jul 25. doi: 10.1111/edt.12776. Online ahead of print.

ABSTRACT

BACKGROUND/AIM: It is not known whether the mechanism of facial trauma influences the associated length of hospitalization. The aim of this study was to determine whether the mechanism of injury influenced the length of hospital stay (LOS) among pediatric patients who sustained facial fractures.

MATERIALS AND METHODS: This retrospective cohort study was completed using the Kids’ Inpatient Database (KID). The primary predictor variable was the mechanism of injury. The primary outcome variable was LOS. Linear regression was used to determine independent predictors of increased/decreased length of stay. A p-value of less than .05 was considered statistically significant.

RESULTS: The final sample consisted of 2865 subjects aged 12 years or younger who had suffered facial fractures. The most common mechanism of injury was motor vehicle accidents (MVA) (58.6%). Facial fractures due to MVA added 1.20 days (95% CI, 0.02, 2.38; p < .05) when compared to those due to a fall.

CONCLUSIONS: MVA significantly prolonged the LOS among young pediatric patients who sustained facial fractures, reflecting the exceptional amount of force involved. Having a chronic condition was also a significant factor for longer LOS. Four or more fractures also led to a longer LOS.

PMID:35877474 | DOI:10.1111/edt.12776

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Nevin Manimala Statistics

Analysis of Spanish Parents’ Knowledge about ASD and Their Attitudes towards Inclusive Education

Eur J Investig Health Psychol Educ. 2022 Jul 21;12(7):870-881. doi: 10.3390/ejihpe12070063.

ABSTRACT

To make possible the inclusion of children with autism spectrum disorder (ASD) in mainstream settings, parental knowledge and attitudes towards the disorder play a key role between the home and the school setting. However, prior literature has not carried out an in-depth analysis of parents’ knowledge about ASD and their attitudes toward the inclusion of children with this diagnosis. This study examined the parental attitudes towards inclusion and knowledge about ASD. Participants were parents of children with ASD (n = 75), parents of children without ASD whose children had prior or current contact with peers with ASD (n = 44), and parents of children with no previous interactions with a peer with ASD (n = 51). The Attitudes of Regular Educators Towards Inclusion for Students with Autism Survey and the Autism Knowledge Questionnaire were filled out. Nonparametric statistical tests were used. Results showed that parents of children with ASD have better knowledge about this disorder and hold more favorable attitudes towards the inclusion of children with ASD than the other parents. These findings suggest that the benefits of inclusive schooling are limited to the school setting and do not appear to affect families of children without ASD.

PMID:35877463 | DOI:10.3390/ejihpe12070063