The examination of Haplotypes makes it possible to understand the heritability of certain complex traits. However, genome analysis of family members is usually necessary, a tedious and expensive process. Researchers have developed SHAPEIT4, a powerful computer algorithm that allows the haplotypes of hundreds of thousands of unrelated individuals to be identified very quickly. Results are as detailed as when family analysis is performed. Their tool is available online under an open source license.
Tag: statistics
Mathematicians have developed a new model to explore what the impact of changes to Luftwaffe tactics would actually have been. Their approach uses statistical modelling to calculate how the Battle might have played out if history had followed one of several alternative courses.
What rules shaped humanity’s original social networks? The earliest social networks were tightly knit cultural groups made of multiple biologically related families. That single group would then develop relationships with other cultural groups in their local area. Researchers used statistical physics and computer models common in evolutionary biology to explain the origin of common community structures documented by cultural anthropologists around the world.
Theoretical physicists have found a deep link between one of the most striking features of quantum mechanics — quantum entanglement — and thermalization, which is the process in which something comes into thermal equilibrium with its surroundings.
With some reports predicting the precision agriculture market will reach $12.9 billion by 2027, there is an increasing need to develop sophisticated data-analysis solutions that can guide management decisions in real time. A new study offers a promising approach to efficiently and accurately process precision agricultural data.
Psychiatrists have used a computer-based approach to assign psychotic patients diagnosed as bipolar or schizophrenic to five different subgroups. The method could lead to better therapies for psychoses.
Despite the near-universal assumption of individuality in biology, there is little agreement about what individuals are and few rigorous quantitative methods for their identification. A new approach may solve the problem by defining individuals in terms of informational processes.
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| Related Articles |
Fracture Toughness Comparison of Three Indirect Composite Resins Using 4-Point Flexural Strength Method.
Eur J Dent. 2020 Apr 13;:
Authors: Moradi Z, Abbasi M, Khalesi R, Tabatabaei MH, Shahidi Z
Abstract
OBJECTIVES: The advantages of indirect composite restorations such as less crack formation during their computer-aided design/computer-aided manufacturing process, compared with ceramic restorations, have resulted in their growing popularity. However, restoration failure is a major concern with regard to the long-term clinical success of restorations and may occur as the result of propagation of a crack originated from an internal flaw in the restoration. This study aimed to compare the fracture toughness of three indirect composite resins.
MATERIALS AND METHODS: In this in vitro experimental study, 10 specimens measuring 3 × 3 × 18 mm were fabricated of Gradia, Crios, and high impact polymer composite indirect composites. A single edge notch with a diameter < 0.3 mm and 0.3 mm length was created in the 9 mm longitudinal dimension of specimens using a no. 11 surgical scalpel. The specimens were then subjected to 4-point flexural strength test in a universal testing machine with a crosshead speed of 0.1 mm/s until failure.
STATISTICAL ANALYSIS: Data were analyzed using IBM SPSS Statistics via one-way analysis of variance (ANOVA) and Tukey’s HSD (honestly significant difference) test. The statistical power was set at p ˂ 0.05.
RESULTS: One-way ANOVA showed a significant difference in fracture toughness of the three composite groups (p = 0.000). According to the Tukey HSD analysis, the fracture toughness of HIPC was significantly higher than that of the other two composites. The fracture toughness of Gradia was significantly lower among all.
CONCLUSIONS: Within the limitations of this study, the results showed that high temperature-pressure polymerization can increase resistance to crack propagation and subsequently improve the clinical service of indirect composite restorations. Although we do not know the filler volume percentage of HIPC, it seems that filler volume percentage of the composite is inversely correlated with fracture toughness.
PMID: 32283561 [PubMed – as supplied by publisher]