Clin Oral Implants Res. 2021 Mar 13. doi: 10.1111/clr.13745. Online ahead of print.
ABSTRACT
OBJECTIVES: To analyze the long-term effect of plaque formation on implant abutments with an antibacterial coating and the ensuing host response in peri-implant tissues.
MATERIALS & METHODS: Four implants were installed in each mandibular premolar region following tooth extraction in 6 dogs. Three months later 2 test abutments with a Titanium-Bismuth-Gallium (Ti-Bi-Ga) coating and 2 control titanium abutments were connected to the implants on each side of the mandible. After 2 months ligatures were placed around the implants in one side of the mandible and plaque formation was allowed until the end of the experiment. The ligatures were removed after 4 weeks. Radiographs and microbiological samples were obtained from each implant site during the plaque formation period. Biopsies were obtained 8 months after abutment connection and prepared for histological analysis.
RESULTS: The analysis did not reveal any statistically significant differences in bone loss, bacterial growth and size of inflammatory lesions between implant units with and without the Ti-Bi-Ga coating. Implant sites exposed to the short period of ligature induced breakdown demonstrated more pronounced bone loss and bacterial growth than non-ligature sites.
CONCLUSIONS: It is suggested that a Ti-Bi-Ga coating does not prevent biofilm formation on the implant device and does not influence the ensuing host response in the adjacent peri-implant mucosa.
PMID:33715254 | DOI:10.1111/clr.13745
