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Risk factors for presence of cystoid macular edema following rhegmatogenous retinal detachment surgery

Curr Eye Res. 2021 May 12. doi: 10.1080/02713683.2021.1929330. Online ahead of print.

ABSTRACT

PURPOSE: Cystoid macular edema (CME) following cataract surgery is a well-known entity. Less is known regarding the risk factors of developing CME following repair of rhegmatogenous retinal detachments (RRD).

METHODS: This was a multi-institutional study of primary RRD surgeries from 1/1/2015 through 12/31/2015. The primary outcome was development of post-operative CME following RRD surgery. Post-operative optical coherence tomography imaging and 3 months of follow up following RRD repair were required.

RESULTS: There were 1,466 eyes that met the inclusion criteria, and 140 (9.6%) developed post-operative CME following primary RRD repair. On multivariate analysis the statistically significant metrics were older patient age (OR 1.03 per year, 95% CI 1.01 to 1.05), pre-operative proliferative vitreoretinopathy (PVR, OR 1.74, 95% 1.03 to 2.95), and cataract surgery following RRD repair (OR 2.18, 95% CI 1.47 to 3.25). Single surgery success was protective against CME (OR 0.20 (95% CI 0.14 – 0.30). Seventy-six (9.0%) of the phakic eyes and 60 (9.9%) of the pseudophakic eyes, developed post-operative CME. Multivariate analysis showed that cataract surgery following RRD repair (p < 0.0001) for phakic eyes and older age (p = 0.0075) for pseudophakic eyes were risk factors. In eyes that underwent successful retinal re-attachment with one surgery, post-operative cataract surgery (p = 0.0005) and pre-operative PVR (p = 0.0011) were risk factors for CME in this subgroup.

CONCLUSION: CME occurred in nearly 10% of eyes following RRD repair. The biggest risk factors were recurrent RRD, preexisting PVR, older age, and cataract surgery following RRD repair.

PMID:33979556 | DOI:10.1080/02713683.2021.1929330

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