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Trends of Severe Hypoglycemia in Patients with Type 2 Diabetes in Korea: A Longitudinal Nationwide Cohort Study

J Diabetes Investig. 2022 Mar 9. doi: 10.1111/jdi.13786. Online ahead of print.

ABSTRACT

To estimate the trends in the prevalence of severe hypoglycemia (SH) in patients with type 2 diabetes (T2D) in Korea, we investigated the total number of SH episodes among T2D patients aged ≥30 years who visited the emergency department between 2002 and 2019, using the Korean National Health Insurance Service database. The prevalence of SH events increased from 2002 to 2012; however, it has decreased gradually since 2012. In 2019, the prevalence of SH was 0.6%, with an incidence rate of 4.43 per 1,000 person-years. Approximately 23,000 SH events occur every year in Korea. Although the incidence is steadily decreasing, there are a considerable number of SH events in T2D patients. The decline in the incidence of SH seems to most likely be due to the increased prescription rate of hypoglycemic agents without hypoglycemia risk, less strict treatment goals, and the individualization of therapy.

PMID:35263509 | DOI:10.1111/jdi.13786

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