Nevin Manimala Statistics

Inconsistency between overall and subgroup analyses

Gen Psychiatr. 2022 May 16;35(3):e100732. doi: 10.1136/gpsych-2021-100732. eCollection 2022.


Suppose we have a sample of subjects in two treatment groups. To study the difference of the treatment effects, we can analyse the data using all subjects (overall analysis). We may also divide the subjects into several subgroups based on some covariates of interest (eg, gender), and study the treatment effects within each subgroup. The results of these two analyses may be different or even in opposite directions. In this paper, we give a general sufficient condition of consistency between the overall and subgroup analyses.

PMID:35677850 | PMC:PMC9114839 | DOI:10.1136/gpsych-2021-100732

By Nevin Manimala

Portfolio Website for Nevin Manimala