J Occup Environ Med. 2022 Jun 9. doi: 10.1097/JOM.0000000000002588. Online ahead of print.
OBJECTIVES: To examine the association and potential mediators between rotating night shift work and serum lipid profiles in Chinese steelworkers.
METHODS: Different exposure metrics of night shifts collected through face-to-face personal interviews. Serum lipid profiles were measured using an automatic biochemical analyzer. Generalized linear models and mediation analyses were used to analyze the main associations.
RESULTS: Compared with day workers, the total cholesterol level in night shift workers increased in those with 13-20 years of night shifts and in those with ≥4 nights/month average frequency of night shifts. The association between the duration of night shifts and the total cholesterol level was mediated by systolic and diastolic blood pressure and BMI.
CONCLUSIONS: Rotating night shift work for 13-20 years was associated with an increase in the total cholesterol levels in steelworkers, and blood pressure and BMI may be involved in the causal pathway.