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Do neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) have a role in determining mortality in intensive care patients undergoing plasmapheresis? Single-Center Experience

Ther Apher Dial. 2022 Jun 22. doi: 10.1111/1744-9987.13900. Online ahead of print.


INTRODUCTION: Plasmapheresis is a frequently used procedure that removes the pathogenic components from circulation. We aimed to evaluate the relationship between plasmapheresis, neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and mortality in the intensive care unit (ICU) between 2014 and 2021.

METHODS: 49 patients (27 females and 22 males) were included. Demographic characteristics, laboratory values of the day of admittance to the ICU, APACHE II scores, and length of stay were recorded.

RESULTS: The mean age was 52.73±16.93. APACHE II value (p=0.003; p<0.01), NLR ratio (p=0.001; p<0.01) and PLR ratio (p=0.001; p<0.01) of the surviving group were lower than those of the deceased group, which was statistically significant.

CONCLUSION: As high PLR and NLR levels suggest increased mortality in the ICU population, attention should be paid for increased NLR and PLR when plasmapheresis is decided on in the ICU.

PMID:35730341 | DOI:10.1111/1744-9987.13900

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