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A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana

AIDS Res Ther. 2022 Jun 23;19(1):26. doi: 10.1186/s12981-022-00454-3.

ABSTRACT

We conducted a pilot trial of an intervention targeting intersectional stigma related to being pregnant and living with HIV while promoting capabilities for achieving ‘respected motherhood’ (‘what matters most’) in Botswana. A pragmatic design allocated participants to the intervention (N = 44) group and the treatment-as-usual (N = 15) group. An intent-to-treat, difference-in-difference analysis found the intervention group had significant decreases in HIV stigma (d = – 1.20; 95% CI – 1.99, – 0.39) and depressive symptoms (d = – 1.96; 95% CI – 2.89, – 1.02) from baseline to 4-months postpartum. Some, albeit less pronounced, changes in intersectional stigma were observed, suggesting the importance of structural-level intervention components to reduce intersectional stigma.

PMID:35739534 | DOI:10.1186/s12981-022-00454-3

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