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Analysis of inhalation allergen of patients with allergic rhinitis in Shenzhen

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Jun;36(6):467-472. doi: 10.13201/j.issn.2096-7993.2022.06.012.

ABSTRACT

Objective:To analyzed allergens and screen for common airborne allergens in patients with allergic rhinitis (AR) in Shenzhen, and identified the distribution pattern of allergens in this region. We aimed to provide scientific and feasible statistical and clinical basis for prevention and treatment of allergenic rhinitis. Methods:For 3351 suspected cases of allergenic rhinitis, 18 kinds of airborne allergen serum-specific IgE were determined using a detection system of BioSciTec GmbH company, and statistical analysis was carried out according to sex, age, severity and seasonal allergen. Results:A total of 3,351 cases with allergic rhinitis were positive for airborne allergens. The top five inhalation allergens were Blomia tropicalis (2231, 66.6%), Dermatophagoides pterronyssinus (2212, 66.0%), Dermatophagoides farinae (1986, 59.3%), Cockroach (967, 28.9%), and Short ragweed (844, 25.2%). For the severity of the allergen, Dermatophagoides pterronyssinus ≥ level 3 accounted for 41.3% (1385/3351 cases) and Dermatophagoides farinae ≥level 3 accounted for 40.6% (1360/3351 cases). Blomia tropicalis were classified as level 2, and other allergens were mainly classified as level 1 or 2. The detection rate among different age groups and gender is significantly different. Conclusion:The main airborne allergens in Shenzhen were Blomia tropicalis, Dermatophagoides pterronyssinus, Dermatophagoides farinae, Cockroach, as well as Short ragweed. The distribution of allergens was affected by sex, age and season.

PMID:35822367 | DOI:10.13201/j.issn.2096-7993.2022.06.012

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