Nevin Manimala Statistics

Supervised Physical Activity Quickly Improves Social Dimension of Quality of Life in Breast Cancer Patients

Med Sci Sports Exerc. 2022 Jul 19. doi: 10.1249/MSS.0000000000003005. Online ahead of print.


PURPOSE: The objective of the present study was to evaluate the implementation of the program in real life and the evolution of the QoL in breast cancer patients after 3 months of supervised PA in real-life and to determine the factors associated with changes in various QoL dimensions.

METHODS: This prospective cohort study was carried out in female patients with breast cancer diagnosed within a maximum of 3 years. QoL and physical exertion intensity during the supervised PA sessions were assessed by the QLQ-C30 and Borg scale, respectively. Statistical analyzes comparing QoL scores between the start and the end of supervised PA program were assessed using paired Student’s t tests. Multivariate analysis was performed by linear regression with only variables with a p-value <0.15 in univariate model.

RESULTS: A total of 93 patients were included in the analyzes. There was a significant improvement of social functioning at T3 (∆ = 11.5; p < 0.001). The improvement of social functioning was significantly and independently associated to the BORG improvement (β = 2.66 ± 1.31, p = 0.046), chemotherapy (β = 11.03 ± 5.45, p = 0.046), hormone therapy (β = -13.91 ± 5.51, p = 0.013), social isolation (β = -14.81 ± 6.55, p = 0.026) and comorbidities (β = -15.32 ± 5.59, p = 0.007).

CONCLUSIONS: We observed a real enthusiasm and need among patients for practicing physical activity supervised by a sport trainer near their home. The increase in the intensity of exercise over time contributes to the improvement of the QoL, especially on the social functioning. These results, consistent with previous literature, reinforce the importance of exercise intensity on many dimensions of QoL. In addition, patients expressed great satisfaction with the supervised program, resulting in a strong desire to maintain long-term physical activity.

PMID:35881932 | DOI:10.1249/MSS.0000000000003005

By Nevin Manimala

Portfolio Website for Nevin Manimala