Mycoses. 2022 Aug 3. doi: 10.1111/myc.13511. Online ahead of print.
BACKGROUND: Malassezia folliculitis (MF) is a humid-favored fungal skin disease caused by Malassezia species. Inaccurate treatments, changes in skin flora, and disease exacerbation are often occurred due to oversights in the diagnosis. Several diagnostic methods are established for MF.
OBJECTIVE: To identify clinico-laboratory findings of Malassezia folliculitis in Indonesia.
METHODS: The study was conducted from January 2014 to December 2018 in seven referral teaching hospitals. Medical records of MF-diagnosed patients were obtained and analyzed using the binomial test, chi-square test, and Cohen’s Kappa coefficient in SPSS 26.0.
RESULTS: A total of 353 cases of MF were identified in seven referral teaching hospitals in Indonesia, 66.3% of which were males and 33.7% were females, dominated by the 17-25 years old group (44.5%). Itchy sensation (83.9%) was a major subjective complaint. Lesions were majorly found on the trunk-chest, back, and shoulder (68.3%), while the clinical manifestation are mostly follicular papule-pustular lesions (62.1%). Patients were 87.4% positive by KOH examination (modified Jacinto Jamora’s criteria) and 69.1% positive by Wood’s lamp. Generally, sex, age, subjective complaint, lesion location, clinical manifestation, and both examinations were statistically significant (p<0.001). A significant relationship between all the clinical criteria of the patients in the KOH; especially the clinical manifestation was significantly related to the Wood’s lamp. The Cohen’s Kappa assessment suggested that there was an agreement between KOH and Wood’s lamp (κ = -0,272, p<0.001).
CONCLUSION: The clinical symptoms of Malassezia folliculitis are dominated by pruritus, papulopustular follicular lesions on the trunk, and the presence of spore load.